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Danenberg

Haim Danenberg, Jerusalem IL

Patent application numberDescriptionPublished
20090238876BISPHOSPHONATES FOR TREATING ENDOMETRIOSIS - A novel method of treating endometriosis is disclosed. The method comprises administering to a female subject in need thereof a therapeutically effective amount of particles comprising an agent capable of inhibiting phagocytic cells of the female subject.09-24-2009
20110082483Cutting balloon assembly and method of manufacturing thereof - A cutting balloon assembly and a method for fabrication of the assembly is described. The cutting balloon assembly comprises a delivery catheter, an expandable balloon mounted on the catheter distal end, and a scoring mesh disposed around the expandable balloon. The scoring mesh comprises interlacing filaments that extend from a mesh proximal end towards a mesh distal end, form distal filament loops at said mesh distal end, and then return to the mesh proximal end. At least a part of the interlacing filaments forms one or more permanent links with neighboring filaments between the mesh proximal end and the mesh distal end.04-07-2011

Kathleen Danenberg, Los Angeles, CA US

Patent application numberDescriptionPublished
20090092979METHODS FOR ISOLATING LONG FRAGMENT RNA FROM FIXED SAMPLES - The present invention relates to methods for the extraction of long fragment RNA from fixed tissue specimens. In particular, the present invention relates to methods for the extraction of RNA from formalin-fixed paraffin-embedded tissue specimens for use in biologic applications, including assays based on oligonucleotide hybridization.04-09-2009

Kathleen Danenberg, Altadena, CA US

Patent application numberDescriptionPublished
20090035761Method for isolation of DNA, RNA and proteins from formalin-fixed paraffin-embedded tissue specimens - Methods are disclosed for rapid, reliable and simple isolation of RNA from formalin-fixed paraffin-embedded tissue samples. RNA purified in this manner can be used to monitor gene expression levels. The tissue sample can be a tumor or other pathological tissue.02-05-2009

Kathleen D. Danenberg, Altadena, CA US

Patent application numberDescriptionPublished
20090311708METHOD OF DETERMINING A CHEMOTHERAPEUTIC REGIMEN BASED ON ERCC1 AND TS EXPRESSION - The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a method for assessing TS and/or ERCC1 expression levels in fixed or fixed and paraffin embedded tissues and prognosticate the probable resistance of a patient's tumor to treatment with 5-FU and oxaliplatin-based therapies by examination of the amount of TS and/or ERCC1 mRNA in a patient's tumor cells and comparing it to a predetermined threshold expression level for those genes. More specifically, the invention provides to oligonucleotide primer pairs ERCC1 and TS and methods comprising their use for detecting levels of ERCC1 and TS mRNA, respectively.12-17-2009
20100009365PROCESS FOR HIGH-THROUGHPUT DNA METHYLATION ANALYSIS - There is disclosed an improved high-throughput and quantitative process for determining methylation patterns in genomic DNA samples based on amplifying modified nucleic acid, and detecting methylated nucleic acid based on amplification-dependent displacement of specifically annealed hybridization probes. Specifically, the inventive process provides for treating genomic DNA samples with sodium bisulfite to create methylation-dependent sequence differences, followed by detection with fluorescence-based quantitative PCR techniques. The process is particularly well suited for the rapid analysis of a large number of nucleic acid samples, such as those from collections of tumor tissues01-14-2010

Patent applications by Kathleen D. Danenberg, Altadena, CA US

Noam Danenberg, Hod Hasharon IL

Patent application numberDescriptionPublished
20080221548Eradication of Pigmentation and Scar Tissue - The invention is a non-surgical method for the eradication of pigmentation and scar tissue from an area of skin. The method comprises repeatedly puncturing the area of skin with an array of needles. As the needles are inserted into the skin, the needles and surface of the skin are washed with a clean solution. As the needles are withdrawn from the skin, the flow of clean solution ceases and the dirty solution, which contains cellular fluids and pigments released by the action of the needles, is removed from the surface. The invention is also a solution, which is used to clean the needles and to aid in destroying the pigment containing cells, and an apparatus, which is especially designed to move the needles into and out of the surface of the skin and to provide synchronization of the motion of the needles and flow of the solution such as to maximize the effectiveness of the method.09-11-2008
20100286951FOOT MEASURING DEVICE - The invention presents an apparatus for measuring the dimensions of human feet. The apparatus is comprised of a base (11-11-2010
20110100406SPLIT THERMO-ELECTRIC STRUCTURE AND DEVICES AND SYSTEMS THAT UTILIZE SAID STRUCTURE - The invention is a Split-Thermo-Electric Structure (STES) and devices and systems that utilize said structure. The STES comprises a first thermo-electric element at an elevated temperature and a second thermo-electric element at a low (cold) temperature. The first thermo-electric element and the second thermo-electric element are connected by either an intermediate connection that conducts both electric current and heat or by a thermo-electric chain comprised of one or more thermo-electric elements. Each pair of the thermo-electric elements in the chain are connected by an intermediate connection that conducts both electric current and heat. Each of the thermo-electric elements and each of the intermediate connections in the STES exhibit a temperature-gradient. The STESs can be utilized in Seebeck or Peltier devices. The STESs can be utilized to construct devices comprised a plurality of n-type and p-type pairs of STESs, wherein each of the STESs in the device are connected at each end to a support layer. One of the support layers can be thermally connected to a heat source and the second support layer thermally connected to a heat sink in order to create a thermo-electric system. The heat source or the heat sink or both can be located at a distance from their respective support layer.05-05-2011

Patent applications by Noam Danenberg, Hod Hasharon IL

Peter V. Danenberg, Altadena, CA US

Patent application numberDescriptionPublished
20090035761Method for isolation of DNA, RNA and proteins from formalin-fixed paraffin-embedded tissue specimens - Methods are disclosed for rapid, reliable and simple isolation of RNA from formalin-fixed paraffin-embedded tissue samples. RNA purified in this manner can be used to monitor gene expression levels. The tissue sample can be a tumor or other pathological tissue.02-05-2009