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Damaj, US

Bassam Damaj, San Diego, CA US

Patent application numberDescriptionPublished
20090280202Extracts of Aristolochia Longa pomer and uses thereof - Methods of extracting from a part of a variety of the species 11-12-2009
20090311343Thiazole Compounds, and Compositions and Methods Using Same - The present invention provides, in part, compounds and compositions including a thiazole moiety, that may be useful, for example, for treating cancers, for example kidney cancer.12-17-2009
20100112108Extracts of Aristolochia Longa pomer and uses thereof - Methods of extracting from a part of a variety of the species 05-06-2010
20100184807Methods to inhibit tumor cell growth by using proton pump inhibitors - Methods of treating one or more growth deregulated cells are disclosed: An effective amount of a pharmaceutical composition including a proton pump inhibitor is administered thereby treating a growth deregulated cell outside of the gastric lumen of a subject.07-22-2010

Bassam B. Damaj, San Diego, CA US

Patent application numberDescriptionPublished
20110053864Compositions and methods for modulation of cell migration - A peptide includes SEQ ID NO:3, substitution and addition variants thereof which maintain the ability to activate CD44. A complex includes this peptide or an Å6 polypeptide with a CD44 polypeptide. An isolated polypeptide includes the Link region sequence of human CD44, functionally active fragments thereof, substitution variants, and addition variants. A method of treating a disease characterized by aberrant cell migration and/or invasion includes administering to a subject an effective amount of the peptide of SEQ ID NO:3 or an Å6 polypeptide to bind to a CD44 polypeptide and modulate signal transduction activity for a sufficient period of time to treat the disease. Other methods include using the peptide of SEQ ID NO:3 or an Å6 polypeptide for diagnosing, identifying a subpopulation of subjects responsive to treatment, and screening for compounds that bind a CD44 polypeptide.03-03-2011

Mona B. Damaj, College Station, TX US

Patent application numberDescriptionPublished
20080244794Stem-Regulated, Plant Defense Promoter and Uses Thereof in Tissue-Specific Expression in Monocots - The invention is directed to isolated promoters from stem-regulated, defense-inducible genes, such as OMT promoters. The promoters are useful in expression cassettes and expression vectors for the transformation of plants. Particularly, the invention provides transgenic plants of rice and sugarcane that have been modified such that expression of a heterologous coding sequence is directed by an OMT promoter and is limited to stem tissues or may be upregulated by the presence of a defense-inducing agent. The invention also discloses methods for producing the expression vectors and transgenic plants.10-02-2008
20100011460STEM-REGULATED, PLANT DEFENSE PROMOTER AND USES THEREOF IN TISSUE-SPECIFIC EXPRESSION IN MONOCOTS - The invention is directed to isolated promoters from stem-regulated, defense-inducible genes, such as JAS promoters. The promoters are useful in expression cassettes and expression vectors for the transformation of plants. Particularly, the invention provides transgenic plants of rice and sugarcane that have been modified such that expression of a heterologous coding sequence is directed by an JAS promoter and is limited to stem tissues or may be upregulated by the presence of a defense-inducing agent. The invention also discloses methods for producing the expression vectors and transgenic plants.01-14-2010

Patent applications by Mona B. Damaj, College Station, TX US