Patent application number | Description | Published |
20110162753 | VAPOR RECOVERY PUMP REGULATION OF PRESSURE TO MAINTAIN AIR TO LIQUID RATIO - A method of operating a vapor recovery system that recovers vapors expelled from a vehicle during refueling at a fuel dispensing point and returns the vapors to an underground storage tank through a vapor flow path that is in fluid communication with an air to liquid regulator valve and a vapor pump. The method includes dispensing fuel into the vehicle through the fuel dispensing point, regulating an amount of vapor that is recovered through the fuel dispensing point with the air to liquid regulator valve in proportion to the fuel dispensed into the vehicle, detecting a parameter of the vapor recovery system, and maintaining a substantially constant pressure level in a first portion of the vapor return path that is disposed between the vapor pump and the air to liquid regulator valve. | 07-07-2011 |
20110200474 | INTEGRATED PUMP FOR COMPRESSIBLE FLUIDS - A swash pump for compressible fluids uses sealing contacts made between the nutatable swash plate and the fixed cone plates to centre and locate the inner swash sphere which slides against two resiliently mounted ring seals only, minimising pump friction. A slanted end of a common drive shaft supporting and turned by the rotor of an integrated, variable speed motor causes nutation of the sphere. All bearings, especially axially slidable roller bearings inside the sphere, may settle in position with respect to the common shaft for least frictional loss. This pump is also adapted for pumping explosive gases. | 08-18-2011 |
20130011287 | PUMP OR TURBINE FOR INCOMPRESSIBLE FLUIDS - A rotatable drive shaft in the swash pump or turbine for liquids is supported by one bearing at each end. An integrated motor or dynamo uses the same two bearings. The compound first bearing supports a slanted section of the drive shaft placed inside the inner swash sphere, and transfers rotational power to the attached nutatable swash plate. The second bearing confines rotation of the drive shaft in a defined axis. Either one of the bearings is made to prevent axial movement of the drive shaft, preventing swash pump misalignment. A resilient drive, and an immersed pump are described. | 01-10-2013 |
Patent application number | Description | Published |
20080207676 | Crystalline forms of an 8-Azabicyclo(3.2.1)octane compound - The invention provides a crystalline sulfate salt of 3-endo-(8-{2-[cyclohexylmethyl-((S)-2,3-dihydroxy-propionyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)benzamide or a solvate thereof. The invention also provides pharmaceutical compositions comprising such crystalline salt forms, methods of using such crystalline salt forms to treat diseases associated with mu opioid receptor activity, and processes useful for preparing such crystalline salt forms. | 08-28-2008 |
20090209582 | Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists - The invention relates to benzimidazole-carboxamide 5-HT | 08-20-2009 |
20110184008 | CRYSTALLINE FORMS OF AN 8-AZABICYCLO[3.2.1]OCTANE COMPOUND - The invention provides a crystalline sulfate salt of 3-endo-(8-{2-[cyclohexylmethyl-((S)-2,3-dihydroxy-propionyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)benzamide or a solvate thereof. The invention also provides pharmaceutical compositions comprising such crystalline salt forms, methods of using such crystalline salt forms to treat diseases associated with mu opioid receptor activity, and processes useful for preparing such crystalline salt forms. | 07-28-2011 |
20130303465 | Cylodextrin Complexation Methods for Formulating Peptide Proteasome Inhibitors - This disclosure provides methods for formulating compositions comprising one or more peptide proteasome inhibitors and a cyclodextrin, particularly a substituted cyclodextrin. Such methods substantially increase the solubility and stability of these proteasome inhibitors and facilitate both their manufacture and administration. | 11-14-2013 |
20130303482 | Cylodextrin Complexation Methods for Formulating Peptide Proteasome Inhibitors - This disclosure provides methods for formulating compositions comprising one or more peptide proteasome inhibitors and a cyclodextrin, particularly a substituted cyclodextrin. Such methods substantially increase the solubility and stability of these proteasome inhibitors and facilitate both their manufacture and administration. | 11-14-2013 |
20140080856 | CRYSTALLINE FORMS OF AN 8-AZABICYCLO[3.2.1]OCTANE COMPOUND - The invention provides a crystalline sulfate salt of 3-endo-(8-{2-[cyclohexylmethyl-((S)-2,3-dihydroxy-propionyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)benzamide or a solvate thereof. The invention also provides pharmaceutical compositions comprising such crystalline salt forms, methods of using such crystalline salt forms to treat diseases associated with mu opioid receptor activity, and processes useful for preparing such crystalline salt forms. | 03-20-2014 |
20150111838 | CYCLODEXTRIN COMPLEXATION METHODS FOR FORMULATING PEPTIDE PROTEASOME INHIBITORS - This disclosure provides methods for formulating compositions comprising one or more peptide proteasome inhibitors and a cyclodextrin, particularly a substituted cyclodextrin. As well as cyclodextrin complexation methods of formulating a peptide proteasome inhibitor (e.g., a compound of formula (1)-(5) or a pharmaceutically acceptable salt thereof) with one or more cyclodextrins. Such methods substantially increase the solubility and stability of these proteasome inhibitors and facilitate both their manufacture and administration. For example, homogenous solutions of a compound of formula (5) (carfilzomib) can be obtained at a pharmaceutically useful pH (e.g., about 3.5) and at higher concentrations (e.g., about 5 mg/mL) than could be obtained without one or more cyclodextrins and the processes of complexation between the compound and one or more cyclodextrins provided herein. | 04-23-2015 |
Patent application number | Description | Published |
20100029946 | CRYSTALLINE FORM OF A BENZIMIDAZOLE-CARBOXAMIDE MEDICINAL COMPOUND - The invention provides crystalline forms of the novel benzimidazole-carboxamide 5-HT | 02-04-2010 |
20100144881 | CRYSTALLINE FORMS OF A 3-CARBOXYPROPYL-AMINOTETRALIN COMPOUND - The invention provides crystalline solid forms of (S)-4-((2S,3S)-7-carbamoyl-1,1-diethyl-3-methoxy-1,2,3,4-tetrahydronaphthalen-2-ylamino)-2-cyclohexylmethyl-butyric acid. The invention also provides pharmaceutical compositions comprising such crystalline solid forms, methods of using such crystalline solid forms to treat diseases associated with mu opioid receptor activity, and processes useful for preparing such crystalline solid forms. | 06-10-2010 |
20110201644 | CRYSTALLINE FORM OF A BENZIMIDAZOLE-CARBOXAMIDE MEDICINAL COMPOUND - The invention provides crystalline forms of the novel benzimidazole-carboxamide 5-HT | 08-18-2011 |
20120088834 | CRYSTALLINE FORMS OF A 3-CARBOXYPROPYL-AMINOTETRALIN COMPOUND - The invention provides crystalline solid forms of (S)-4-((2S,3S)-7-carbamoyl-1,1-diethyl-3-methoxy-1,2,3,4-tetrahydronaphthalen-2-ylamino)-2-cyclohexylmethyl-butyric acid. The invention also provides pharmaceutical compositions comprising such crystalline solid forms, methods of using such crystalline solid forms to treat diseases associated with mu opioid receptor activity, and processes useful for preparing such crystalline solid forms. | 04-12-2012 |
20130065916 | CRYSTALLINE FORMS OF A 3-CARBOXYPROPYL-AMINOTETRALIN COMPOUND - The invention provides crystalline solid forms of (S)-4-((2S,3S)-7-carbamoyl-1,1-diethyl-3-methoxy-1,2,3,4-tetrahydronaphthalen-2-ylamino)-2-cyclohexylmethyl-butyric acid. The invention also provides pharmaceutical compositions comprising such crystalline solid forms, methods of using such crystalline solid forms to treat diseases associated with mu opioid receptor activity, and processes useful for preparing such crystalline solid forms. | 03-14-2013 |
20130072515 | CRYSTALLINE FORMS OF AN 8-AZABICYCLO[3.2.1]OCTANE COMPOUND - The invention provides a crystalline sulfate salt of 3-endo-(8-{2-[cyclohexylmethyl-((S)-2,3-dihydroxy-propionypamino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl) benzamide or a solvate thereof. The invention also provides pharmaceutical compositions comprising such crystalline salt forms, methods of using such crystalline salt forms to treat diseases associated with mu opioid receptor activity, and processes useful for preparing such crystalline salt forms. | 03-21-2013 |
20130345466 | CRYSTALLINE FORMS OF A 3-CARBOXYPROPYL-AMINOTETRALIN COMPOUND - The invention provides crystalline solid forms of (S)-4-((2S,3S)-7-carbamoyl-1,1-diethyl-3-methoxy-1,2,3,4-tetrahydronaphthalen-2-ylamino)-2-cyclohexylmethyl-butyric acid. The invention also provides pharmaceutical compositions comprising such crystalline solid forms, methods of using such crystalline solid forms to treat diseases associated with mu opioid receptor activity, and processes useful for preparing such crystalline solid forms. | 12-26-2013 |