Inventors list |
Assignees list |
Classification tree browser |
Top 100 Inventors |
Top 100 Assignees |
Dai, WA
Dao-Fu Dai, Seattle, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20110082084 | METHODS FOR THE PREVENTION OR TREATMENT OF HEART FAILURE - The disclosure provides methods of preventing or treating heart failure in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof. | 04-07-2011 |
Fei Dai, Seattle, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20110184913 | DISTRIBUTED DATA BACKUP - One or more techniques and/or systems are disclosed herein for backing up in-memory working store data. A first server in a plurality of connected servers detects a data change for a key-value pair the distributed in-memory working store. The first server determines a backup location for storing a copy of the key-value pair, which is comprised on a backup location server from the plurality of connected servers, by using a key from the key-value pair to identify the backup location server, and determine if the backup location server is available to store the backup copy. The first server sends the backup copy to the backup location server without prior permission from the backup location server and without subsequent feedback from the backup location server concerning the sending of the backup copy. | 07-28-2011 |
Honghua Dai, Redmond, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20090248663 | ONLINE TARGET LOCATION DETECTION - Documents are provided that are geographically relevant to a user or a request. Information describing the online activity of a user is received and location identifiers are obtained. The plurality of location identifiers provide geographic location information defining the geographic intent of the information describing the online activity of the user, the location of the computing device utilized by the user, or the user's registered geographic location. Sets of predefined rules are then applied to the received information and the plurality of location identifiers to select at least one geographic location. Documents are then returned to the user that are geographically relevant based on the selected geographic location. The received information may include search queries, and the documents may include search results and/or advertisements. | 10-01-2009 |
Honghua (kathy) Dai, Redmond, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20080222119 | Detecting a user's location, local intent and travel intent from search queries - A search query history for a user is analyzed to determine a home location of the user. Subsequent search queries are analyzed to discern whether the search query contains local intent, meaning that the search query requests information having an area of geographic relevance. In cases where a search query has local intent, the area of geographic relevance for that search query is compared to the home location of the user to determine whether the search query suggests an intent to travel. | 09-11-2008 |
| 20100049609 | GEOGRAPHICALLY TARGETED ADVERTISING - Methods and computer storage media for geographically targeting online advertisements. A search query is received from a searcher. A geographic location that is associated with the search query is identified and converted to a geographic identifier. A geographic tolerance associated with the search query is determined. An advertisement is matched to the search query based, in part, on the geographic identifier and the geographic tolerance of the search query. The matched advertisement is presented to the searcher. In some embodiments, the advertisement includes an associated geographic tolerance that is utilized for ranking the advertisement. In some embodiments, the direction of travel associated with the searcher is utilized, in part, to rank the advertisement. | 02-25-2010 |
Hongyue Dai, Bothell, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20090157326 | Diagnosis and prognosis of breast cancer patients - The present invention relates to genetic markers whose expression is correlated with breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. The invention relates to methods of using these markers to distinguish these conditions. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the statistical methods disclosed herein. | 06-18-2009 |
| 20110301048 | DIAGNOSIS AND PROGNOSIS OF BREAST CANCER PATIENTS - The present invention relates to genetic markers whose expression is correlated with breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate clinical conditions associated with breast cancer, such as the presence or absence of the estrogen receptor ESR1, and BRCA1 and sporadic tumors, and to provide information on the likelihood of tumor distant metastases within five years of initial diagnosis. The invention relates to methods of using these markers to distinguish these conditions. The invention also relates to kits containing ready-to-use microarrays and computer software for data analysis using the statistical methods disclosed herein. | 12-08-2011 |
Hongyue Dai, Kenmore, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20090004645 | Methods for Identifying Genes that Mediate a Response of a Living Cell to an Agent - In one aspect, the present invention provides methods for determining whether a gene mediates the response of a living cell to an agent. In another aspect, the present invention provides methods to identify a mammalian subject responsive to a KSP inhibitor. | 01-01-2009 |
| 20090239214 | Prognosis of breast cancer patients - The present invention relates to sets of genetic markers whose expression is correlated with prognosis of breast cancer in individuals having breast cancer. Specifically, the invention provides sets of markers whose expression patterns can be used to differentiate individuals having a good prognosis, e.g., no reoccurrence or metastasis within five years of initial diagnosis, and individuals having a poor prognosis, e.g., reoccurrence or metastasis within five years of initial diagnosis. The invention relates to methods of prognosis using these markers. The invention also relates to microarrays containing probes to these markers, and to kits containing ready-to-use microarrays and computer software for data analysis using the prognostic and statistical methods disclosed herein. | 09-24-2009 |
| 20100113287 | METHODS FOR ASSESSING THE REPRESENTATION OF NUCLEIC ACID MOLECULES IN A NUCLEIC ACID LIBRARY - The invention provides methods for evaluating the representation of expected nucleic acid molecules in a test population of nucleic acid molecules. The methods each comprise the steps of: (a) hybridizing a population of sample nucleic acid molecules obtained from a test population of nucleic acid molecules to a substrate comprising a population of target nucleic acid molecules, wherein (i) each target nucleic acid molecule comprises a predetermined sequence corresponding to an expected nucleic acid molecule, and (ii) each target nucleic acid molecule is localized to a defined area of the substrate; and (b) evaluating the representation of expected nucleic acid molecules in the test population of nucleic acid molecules by analyzing the pattern of hybridization of the sample population of nucleic acid molecules to the target nucleic acid molecules. | 05-06-2010 |
Hui Dai, Redmond, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20100192227 | OFFLINE EXTRACTION OF CONFIGURATION DATA - A configuration scanning system is described herein that scans a system configuration database for malware-related information with less impact on other operations that access the system configuration database. The system employs techniques to reduce the impact on other operations that access the configuration database, including parsing a file-based stored version of the configuration database, accessing the configuration database using opportunistic locking, and caching configuration information obtained by scanning the configuration database. In this way, the system is able to respond to requests antimalware programs using cached information without impacting other programs using the configuration database. Thus, the configuration scanning system protects a computer system against malware while reducing the burden on the configuration database and on other programs that access the configuration database. | 07-29-2010 |
James Dai, Redmond, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20080235204 | Using user feedback to improve search results - The invention discloses a system and method for managing feedback data that will be used for ranking search results. The invention can aggregate a plurality of user feedback data from more than one user into a search index. The user feedback data can be associated with one or more documents within the index such that the one or more documents can be ranked based on the type of feedback data that is aggregated. Once the documents have been ranked, the ranked documents can be provided to a requester. | 09-25-2008 |
Peng Dai, Seattle, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20110313933 | Decision-Theoretic Control of Crowd-Sourced Workflows - Systems and methods for the decision-theoretic control and optimization of crowd-sources workflows utilize a computing device to map a workflow to complete a directive. The directive includes a utility function, and the workflow comprises an ordered task set. Decision points precede and follow each task in the task set, and each decision point may require (a) posting a call for workers to complete instances of tasks in the task set; (b) adjusting parameters of tasks in the task set; or (c) submitting an artifact generated by a worker as output. The computing device accesses a plurality of workers having capability parameters that describe the workers' respective abilities to complete tasks. The computing device implements the workflow by optimizing and/or selecting user-preferred choices at decision points according to the utility function and submits an artifact as output. The computing device may also implement a training phase to ascertain worker capability parameters. | 12-22-2011 |
Xudong Dai, Kirkland, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20110166028 | METHODS FOR PREDICTING TREATMENT RESPONSE BASED ON THE EXPRESSION PROFILES OF BIOMARKER GENES IN NOTCH MEDIATED CANCERS - The invention relates to the identification and use of gene expression profiles with clinical relevance to the treatment of cellular proliferative disorders, especially those mediated by aberrant Notch signaling using a Notch signaling inhibitor. In particular, the invention provides the identities of genes, whose individual or cumulative expression patterns may be useful in various assays. The gene expression profiles, whether embodied in nucleic acid expression, protein expression, or other expression formats, may be used to select subjects afflicted with a Notch mediated cancer who will likely respond to treatment with a gamma-secretase inhibitor or another Notch inhibiting agent. The same markers may be used in the classification of patients being treated with other Notch inhibitors. The methods may further comprise providing diagnostic, prognostic, or predictive information based on the classifying step. The methods may further comprise selecting a treatment based on the classifying step. | 07-07-2011 |
| 20110166200 | METHODS OF USING MIR210 AS A BIOMARKER FOR HYPOXIA AND AS A THERAPEUTIC AGENT FOR TREATING CANCER - The present invention provides compositions and methods for predicting the hypoxia response in tumor cells, methods for predicting the likelihood of cancer metastasis, and methods for inhibiting tumor cell proliferation using a microRNA comprising miR-210. | 07-07-2011 |
Ziyu Dai, Richland, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20090042302 | Isolated Polynucleotides and Methods of Promoting a Morphology in a Fungus - The invention includes isolated polynucleotide molecules that are differentially expressed in a native fungus exhibiting a first morphology relative to the native fungus exhibiting a second morphology. The invention includes a method of enhancing a bioprocess utilizing a fungus. A transformed fungus is produced by transforming a fungus with a recombinant polynucleotide molecule. The recombinant polynucleotide molecule contains an isolated polynucleotide sequence linked operably to a promoter. The polynucleotide sequence is expressed to promote a first morphology. The first morphology of the transformed fungus enhances a bioprocess relative to the bioprocess utilizing a second morphology. | 02-12-2009 |
| 20090068723 | Isolated Fungal Promoters and Gene Transcription Terminators and Methods of Protein and Chemical Production in a Fungus - The present invention encompasses isolated gene regulatory elements and gene transcription terminators that are differentially expressed in a native fungus exhibiting a first morphology relative to the native fungus exhibiting a second morphology. The invention also encompasses a method of utilizing a fungus for protein or chemical production. A transformed fungus is produced by transforming a fungus with a recombinant polynucleotide molecule. The recombinant polynucleotide molecule contains an isolated polynucleotide sequence linked operably to another molecule comprising a coding region of a gene of interest. The gene regulatory element and gene transcription terminator may temporally and spatially regulate expression of particular genes for optimum production of compounds of interest in a transgenic fungus. | 03-12-2009 |