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Curie
Brooke M. Curie, Washington, DC US
| Patent application number | Description | Published |
|---|---|---|
| 20100168012 | HUMAN CANCER THERAPY USING ENGINEERED MATRIX METALLOPROTEINASE-ACTIVATED ANTHRAX LETHAL TOXIN THAT TARGETS TUMOR VASCULATUTURE - The present invention provides methods for inhibiting tumor associated angiogenesis by administering a mutant protective antigen protein comprising a matrix metalloproteinase-recognized cleavage site in place of the native protective antigen furin-recognized site in combination with a lethal factor polypeptide comprising a protective antigen binding site. Upon cleavage of the mutant protective antigen by a matrix metalloproteinase, the lethal factor polypeptide is translocated into cancer and endothelial cells and inhibits tumor associated angiogenesis. | 07-01-2010 |
Kevin J. Curie, Appleton, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20090233025 | Multi-Seal Method Capable Structures for Gusseted Flexible Containers - Flexible films, packages, and methods of making the same are provided where the film is capable of being sealed to itself or to other films by more than one sealing method, including thermal sealing and ultrasonic sealing. In particular, a package includes at least three multilayer films sealed together with an ultrasonic seal, where the outer layers remain intact and do not contain visible perforations at the ultrasonic seal. The multilayer films include at least a sealant layer and an outer layer, and may be separate pieces of multilayer films or one multilayer film that has been folded. A method for sealing a film includes the steps of providing a multilayer film having at least a sealant layer and an outer layer, folding the multilayer film to provide a folded film including at least three layers of multilayer film, and applying mechanical oscillations to seal the folded film. | 09-17-2009 |
| 20090297814 | Innerliner With Cross-Linked Eva - A multilayer film comprising, a cross-linked ethylene copolymer layer such as ethylene vinyl acetate layer, an HDPE layer, and a sealant layer, for use, for example, to form a package for dry food products. The multilayer film has a thickness of less than about 2.0 mils, such as between 1-1.5 mils and a tear strength in the machine direction of greater than 40 grams. | 12-03-2009 |
| 20100151218 | INNERLINER WITH NYLON SKIN LAYER - A multilayer film is provided that comprises a nylon skin layer, a buried high density polyethylene layer, and a sealant layer, for use, for example, to form a package for dry food products. The multilayer film has a thickness of less than about 2.0 mils, such as between 0.8-1.7 mils, a moisture vapor transmission rate of less than about 0.30 g/100 in | 06-17-2010 |
Kevin James Curie, Appleton, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20080284063 | Polypropylene container and process for making the same - A multilayer plastic container comprises a layer of a polypropylene and an intermediate layer directly adjacent the layer of polypropylene wherein at least one of the polypropylene and intermediate layers comprises an adhesive such as maleic anhydride incorporated therein to adhere the layer of polypropylene to the layer of EVOH. | 11-20-2008 |
| 20100044916 | Polypropylene Container and Process for Making the Same - A multilayer plastic container comprises a layer of a polypropylene and an intermediate layer directly adjacent the layer of polypropylene wherein at least one of the polypropylene and intermediate layers comprises an adhesive such as maleic anhydride incorporated therein to adhere the layer of polypropylene to the layer of EVOH. | 02-25-2010 |
Thomas Curie, Bouchenaine FR
| Patent application number | Description | Published |
|---|---|---|
| 20080282362 | Non-invasive real-time in vivo bioluminescence imaging of local Ca+ dynamics in living organisms - A method for bioluminescence imaging in an animal is provided. The method comprises providing a whole animal containing a transcriptionally active nucleic acid sequence encoding a Ca | 11-13-2008 |