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Cumberledge

Michael D. Cumberledge, Gainesville, VA US

Patent application numberDescriptionPublished
20090044011Systems, Devices and Methods for Managing Cryptographic Authorizations - Certain exemplary embodiments can provide a method that includes a proof of authorization for any number of activities within an organization, where the proof of authorization associates a specific set of rights, privileges, permissions and/or powers with a collection of entities, each of which has a distinct digital identity. The proof of authorization allows any entity within the collection of entities to interface with or access one or more specific categories of information and/or one or more physical resources within an organization, according to the set of rights privileges, permissions and/or powers established by the authorization proof. The authorization proof may further include references to authorization proofs issued by other organizations in a federation of organizations.02-12-2009

Susan Cumberledge, Amherst, MA US

Patent application numberDescriptionPublished
20080207504SECRETED FRIZZLED RELATED PROTEIN, sFRP, FRAGMENTS AND METHODS OF USE THEREOF - The invention stems from the discovery that sFRP and fragments thereof can bind to members of the Wnt family of proteins and cause an increase in Wnt biological activity. Furthermore, fragments of sFRP that do not contain the CRD domain are shown to bind to Wnt proteins and modulate Wnt biological activity. Accordingly, the invention provides these sFRP fragments and variants of these fragments, as well as vectors and host cells containing nucleic acid sequences encoding the sFRP fragments and variants.08-28-2008

Susan Cumberledge, Belchertown, MA US

Patent application numberDescriptionPublished
20110177554SECRETED FRIZZLED RELATED PROTEIN, SFRP, FRAGMENTS AND METHODS OF USE THEREOF - The invention stems from the discovery that sFRP and fragments thereof can bind to members of the Wnt family of proteins and cause an increase in Wnt biological activity. Furthermore, fragments of sFRP that do not contain the CRD domain are shown to bind to Wnt proteins and modulate Wnt biological activity. Accordingly, the invention provides these sFRP fragments and variants of these fragments, as well as vectors and host cells containing nucleic acid sequences encoding the sFRP fragments and variants.07-21-2011