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Cui, US
Baozhi Cui, Tallahassee, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20080232997 | Method of producing cobalt-platinum magnetic alloys with improved magnetic properties - A method for processing CoPt alloys with improved magnetic properties. The method includes sealing a sample of a CoPt alloy in an evacuated quartz tube, and heating the alloy to a temperature of approximately 1000 degrees C. to homogenize the alloy for approximately 3 hours. The sample is then cooled at a controlled cooling rate of 120-150 degrees C. per minute to 600 degrees C. The sample is then held at 600 degrees C. for 10 hours to promote isothermal ordering. Finally, the sample is quenched in mineral oil. | 09-25-2008 |
| 20120019341 | COMPOSITE PERMANENT MAGNETS MADE FROM NANOFLAKES AND POWDERS - Composite RE-TM permanent magnets fabricated by using powders and nanoflakes produced by surfactant-assisted, wet, high energy, ball milling, with or without prior dry, high energy, ball milling; where RE represents rare earth elements and TM represents transition metals and where the powders include Fe nanoparticles, Fe—Co nanoparticles, B | 01-26-2012 |
| 20120019342 | Magnets made from nanoflake precursors - RE-TM based permanent magnets (single phase, hybrid, laminated or polymer bonded magnets) fabricated by using nanoflakes produced by surfactant assisted, wet, high energy ball-milling, with or without prior dry high energy ball-milling, where RE represents rare earth elements and TM represents transition metals. | 01-26-2012 |
| 20120021219 | MAGNETIC NANOFLAKES - Magnetic nanoflakes fabricated by surfactant assisted, wet, high energy ball milling of bulk precursors, with or without preceding dry, high energy ball milling, wherein certain nanoflakes indicate hard magnetic properties, crystallographic texture and magnetic anisotropy. | 01-26-2012 |
Bentao Cui, Eden Prairie, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20100090311 | Growth of low dislocation density group-III nitrides and related thin-film structures - Methods of growing Group-III nitride thin-film structures having reduced dislocation density are provided. Methods in accordance with the present invention comprise growing a Group-III nitride thin-film material while applying an ion flux and preferably while the substrate is stationary or non-rotating substrate. The ion flux is preferably applied as an ion beam at a glancing angle of incidence. Growth under these conditions creates a nanoscale surface corrugation having a characteristic features size, such as can be measured as a wavelength or surface roughness. After the surface corrugation is created, and preferably in the same growth reactor, the substrate is rotated in an ion flux which cause the surface corrugation to be reduced. The result of forming a surface corrugation and then subsequently reducing or removing the surface corrugation is the formation of a nanosculpted region and polished transition region that effectively filter dislocations. Repeating such nanosculpted and polished regions advantageously provide significant reduction in dislocation density in thin-film structures. | 04-15-2010 |
Cai-Bin Cui, Chapel Hill, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20110135610 | Multipotent stem cells from the extrahepatic biliary tree and methods of isolating same - The present invention relates to a multipotent stem cell, multipotent cell populations, and an enriched multipotent cell population, each found in fetal, neonatal, pediatric, and adult biliary tree tissue and up to 72 hours post mortem (although preferentially, within 10 hours post mortem) and capable of maturing into multiple endodermal tissues that include liver, biliary and pancreatic tissues. The multipotent stem/progenitor cell and cell populations are found in peribiliary glands, and progenitors descending from them are present throughout the biliary tree including in the gallbladder. High numbers of the peribiliary glands are found in the branching locations of the biliary tree such as hilum, common hepatic duct, cystic duct, common duct, common hepato-pancreatic duct and gallbladder. Related multipotent cells, multipotent cell populations and their descendent progenitors are found throughout the biliary tree including in the gall bladder, which does not have peribiliary glands. Compositions comprising same, methods of identifying and isolating same, maintaining same in culture, expanding same in culture and differentiating or lineage restricting the same in vitro or in vivo to hepatic, biliary or pancreatic fates (e.g., as hepatocytes, cholangiocytes, and/or pancreatic islet cells) are also provided. Methods of using the multipotent cells and/or multipotent cell populations are also provided. | 06-09-2011 |
Chi Cui, College Park, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090096895 | MULTI-SPECTRAL IMAGING - Multi-spectral imaging technique embodiments are presented which involve an active imaging approach that uses wide band illumination of known spectral distributions to obtain multi-spectral reflectance information in the presence of unknown ambient illumination. In general, a reflectance spectral distribution of a captured scene is computed by selecting a number of different illumination spectra and capturing multiple images of the scene. Each of these images is captured when the scene is illuminated by a different one of the selected illumination spectra in addition to the ambient light. The reflectance spectral distribution of the scene is computed for each pixel location based on the relative response between pairs of the radiometric responses of the corresponding pixels in the captured images, given a set of parameters including the added illumination spectra used to capture each of the images and the response function and spectral sensitivity of the camera used to capture the images | 04-16-2009 |
Chongwu Cui, Lexington, KY US
| Patent application number | Description | Published |
|---|---|---|
| 20090153814 | SELF-CLEANING SCAN HEAD ASSEMBLY - A scan head assembly for use in an imaging device for scanning media that uses fluid particles from the atmosphere for cooling an optical system, cleaning existing contamination particles in the scan head assembly and preventing contamination particles from accruing in the scan head assembly. The scan head assembly is enclosed in a chamber housing having an inlet in fluid communication with the scan head assembly and atmosphere. The scan head assembly has an optical system and a cooling mechanism located adjacent to the inlet. During use, the cooling mechanism directs fluid particles from the atmosphere through the inlet across the scan head assembly to provide cooling and cleaning to the scan head assembly, including the optical system. A negative pressure system is created within the scan head assembly to prevent contamination particles from accruing in the optical system. | 06-18-2009 |
Cory Cui, Carmel, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20100169999 | INDUCED CHROMOSOME DOUBLING IN PLANTS - Methods to generate doubled haploid plants and plant components using low mammalian toxicity chromosome doubling agents are disclosed. Chromosome doubling agents provide low mortality rates and higher chromosome doubling rate in plants. | 07-01-2010 |
Dehua Cui, Norhville, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20100253601 | FULL-WINDSHIELD HUD ENHANCEMENT: PIXELATED FIELD OF VIEW LIMITED ARCHITECTURE - A system projects graphics upon a transparent windscreen head-up display of a vehicle. The system includes a graphics projection system projecting light upon the transparent windscreen head-up display and the transparent windscreen head-up display emitting light in a limited field of view based upon the projected light. The transparent windscreen head-up display includes light emitting particles small enough that the transparent windscreen head-up display is substantially transparent. | 10-07-2010 |
Frank Cui, Round Lake, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20090111446 | CellPhone Answering System Without Button or Flip Event - A method and apparatus for operating a cellular telephone are provided. The method includes the steps of detecting a call, monitoring a sensor that detects performance of a predetermined act by a user and activating the cellular telephone to accept the detected call when the monitored sensor changes state in response to performance of the predetermined act. | 04-30-2009 |
Haifeng Cui, King Of Prussia, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080234261 | Preparation of 1,6-Disubstituted Azabenzimidazoles as Kinase Inhibitors - Novel inhibitors of Rho-kinases are disclosed. | 09-25-2008 |
Hao Cui, Gresham, OR US
| Patent application number | Description | Published |
|---|---|---|
| 20100200993 | DIELECTRIC BARRIER LAYER FOR INCREASING ELECTROMIGRATION LIFETIMES IN COPPER INTERCONNECT STRUCTURES - Embodiments of the invention include a copper interconnect structure having increased electromigration lifetime. Such structures can include a semiconductor substrate having a copper layer formed thereon. A dielectric barrier stack is formed on the copper layer. The dielectric barrier stack includes a first portion formed adjacent to the copper layer and a second portion formed on the first portion, the first portion having improved adhesion to copper relative to the second portion and both portions are formed having resistance to copper diffusion. The invention also includes several embodiments for constructing such structures. Adhesion of the dielectric barrier stack to copper can be increased by plasma treating or ion implanting selected portions of the dielectric barrier stack with adhesion enhancing materials to increase the concentration of such materials in the stack. | 08-12-2010 |
Hongliang Cui, West Hartford, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20080257096 | Flexible Parallel Manipulator For Nano-, Meso- or Macro-Positioning With Multi-Degrees of Freedom - The present invention is a friction- and backlash-fee flexible parallel manipulator device. The device is composed of multiple elastic fiber legs with various physical properties, a top platform, and a bottom platform. With multiple degrees of freedom, the motion of the top platform is controlled by the multiple elastic fiber legs whose lengths or curvatures between the top and bottom platforms are controlled based on the required motion of the top platform. The device can be used for nano-, micro-, or meso-manipulation. | 10-23-2008 |
Jian-Guo Cui, New Orleans, LA US
| Patent application number | Description | Published |
|---|---|---|
| 20100004171 | Therapeutic Methods for Neuropathic Pain - The agrin protein was shown to be important in preventing the development of neuropathic pain, as well as in treating neuropathic pain. Both agrin protein and gene expression were shown to be down-regulated in mammals with neuropathic pain. Increasing either agrin gene expression or protein resulted in a decrease in the development of neuropathic pain. Agrin protein or the C-terminal agrin fragments can be administered in a number of ways, preferably by intrathecal injection. In addition, agrin can be increased by administering a compound shown to affect agrin gene expression or agrin protein concentration, e.g., SCP-I and SCP-M1 (also known as JMM). Agrin protein decrease was shown to be prevented by administering an NMDA receptor antagonist, e.g., MK801. Agrin and a C-terminal agrin fragment also induced phosphorylation of the NMDA receptor subunit NR1 at the serine residue site which led to suppression of neuropathic pain. | 01-07-2010 |
Jianyi Cui, Roslindale, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100272997 | DENSIFICATION OF METAL OXIDES - The present invention relates to methods for manufacturing of fully densified nanocrystalline metal oxide ceramic materials at low sintering temperature. Methods of the invention involve dry compaction of a product resulting from hydrothermal treatment of metal ion suspensions and subsequent sintering. The present invention may produce ceramic bodies that exhibit nanocrystalline structural features with measured densities that are found to be extremely similar to the theoretical density. | 10-28-2010 |
Jiayue Cui, Chicago, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20100035892 | METHOD FOR ASSEMBLING HIGH-PURITY CHEMICAL LIBRARIES, COMPOUNDS SUPPRESSING ACETYL COENZYME A CARBOXYLASE ACTIVITIES DISCOVERED BY SAME - The present disclosure provides novel compounds of the formula (I): | 02-11-2010 |
John X. Cui, Rochester Hills, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20090204303 | Method for Determining Trailer Braking Output - A method for providing a trailer equipped with trailer brakes with an electronically controlled trailer braking output to help slow a vehicle/trailer combination as quickly as possible, but in a stable and balanced manner. In situations where a low friction environment is detected, such as a wet or icy road, the present method can brake the trailer in a more aggressive manner than a gain setting would normally allow. This gain-independent segment of the trailer braking output can result in a shorter stopping distance for the vehicle/trailer combination, without causing excessive trailer wheel lockup. | 08-13-2009 |
| 20100152969 | ACTIVE SUSPENSION SYSTEM FOR A VEHICLE AND METHOD OF OPERATING THE SAME - An active suspension system and method for controlling the height of a vehicle. In an exemplary embodiment, the active suspension system receives information from one or more input sources, including both internal and external vehicle inputs, and uses that information to actively control the vehicle height. By doing so, the active suspension system can reduce aerodynamic drag on the vehicle and improve the vehicle's fuel economy, ride comfort, handling, and other aspects of operation. Some examples of external vehicle inputs that may be used include: short-range road and vehicle information, as well as long-range traffic, road and route information. | 06-17-2010 |
| 20110093166 | Temperature Compensation Method for an Air Suspension After Engine Shut-Off - A method for temperature compensating an air spring of an air spring suspension of a motor vehicle after engine shut-off. A desired trim height is obtained. At engine shut-off, the ambient temperature is measured and the temperature of air in the air spring determined. After a wait time (for loading/unloading), a start trim height is measured. A predicted trim height is determined for when the air in the air spring is at the ambient temperature. Finally, the volume of the air in the air spring is selectively adjusted so that when the air in the air spring arrives at the ambient temperature, the trim height will be about the desired trim height. | 04-21-2011 |
Juan Cui, Athens, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20110224913 | METHODS AND SYSTEMS FOR PREDICTING PROTEINS THAT CAN BE SECRETED INTO BODILY FLUIDS - The present invention is directed to methods and systems for predicting protein secretion into bodily fluids. In an embodiment, a method uses a feature set comprising secretory properties of collected proteins to train a classifier, based on the feature set, to recognize protein features corresponding to proteins that are likely to be secreted into a biological fluid. Another method determines, using a trained classifier and identified features of a received protein sequence, the probability of the protein sequence being secreted into a biological fluid. In an embodiment, a system predicts the secretion of proteins into a biological fluid. The system comprises components configured to construct a protein feature set comprising properties of collected proteins, train a classifier to predict features of a protein that is likely to be secreted into the biological fluid, receive a protein sequence, and identify the received protein sequence as a secretory protein. | 09-15-2011 |
Jun Cui, Houston, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20110229560 | NLRC5 AS A TARGET FOR IMMUNE THERAPY - The present invention concerns the enhancement of immune response to microbial infection and/or inflammation-associated disease through at least partial inhibition of NLRC5. The inhibition may be of any suitable means, although in particular cases it is via siRNA agents. In specific embodiments, a particular domain of NLRC5 is targeted by the siRNA. | 09-22-2011 |
Kai Cui, Durham, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20120071417 | METHODS OF INHIBITING CANCER CELL GROWTH WITH HDAC INHIBITORS AND METHODS OF SCREENING FOR HDAC10 INHIBITORS - Methods of inhibiting cancer cell growth using HDAC10 inhibitors are provided. Methods of treating cancer in a subject using HDAC10 inhibitors are also provided. In certain embodiments, at least one second inhibitor selected from an autophagy inhibitor, an AMPK inhibitor, and methyl pyruvate is also used in the methods. Dose packs comprising HDAC10 inhibitors and at least one second inhibitor are provided. Methods of identifying HDAC10 inhibitors are also provided. | 03-22-2012 |
Lijun Cui, Arlington, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100230689 | Novel Metal Core Multi-LED SMD Package and Method of Producing the Same - A new SMD (surface mount devices) package design for efficiently removing heat from LED Chip(s) is involved in this invention. Different from the regular SMD package, which electrical isolated materials like Alumina or AlN are used, the substrate material here is metal like Copper, Aluminum and so on. Also, different from regular design, which most time only has one LED chip inside, current design will at least have two or more LED chips (or chip groups) in one package. All chips are electrical connected via metal blocks, traces or wire-bond. This type of structure is generally fabricated via chemical etching and then filled with dielectric material inside to form a strong package. Because the thermal conductivity of the metal is much higher than the ceramics, the package thermal resistance is much lower than the ceramics based package. Also, the cost of the package is much lower than ceramics package. Moreover, emitting area in one package is much larger than the current arts. | 09-16-2010 |
Meng Cui, Ashburn, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20110108707 | ACOUSTIC ASSISTED PHASE CONJUGATE OPTICAL TOMOGRAPHY - A light microscope for imaging a sample containing one or more fluorescent agents, comprising a source for generating acoustic waves that are focused at a focus in the sample, wherein the acoustic waves frequency shift a frequency of light passing through the focus, thereby creating a frequency shifted light beam; at least one spatial light modulator (SLM) positioned to illuminate the sample with an output beam that is an optical phase conjugate of the frequency shifted light beam, wherein the output beam is a reflection of a first reference beam off one or more pixels of the SLM, and the pixels are for modulating the first reference beam to create the output beam; and a detector positioned to detect fluorescence generated by the output beam exciting the fluorescent agents at the focus in the sample, thereby imaging the sample. | 05-12-2011 |
| 20110109962 | OPTICAL PHASE CONJUGATION 4 PI MICROSCOPE - A 4-Pi microscope for imaging a sample, comprising a first objective for focusing a first light beam on the sample at a spatial point one or more Digital Optical Phase Conjugation (DOPC) devices, wherein the DOPC devices include a sensor for detecting the first light beam that has been transmitted through the sample and inputted on the sensor; and a spatial light modulator (SLM) for outputting, in response to the first light beam detected by the sensor, a second light beam that is an optical phase conjugate of the first light beam; and a second objective positioned to transmit the first light beam to the sensor and focus the second light beam on the sample at the spatial point, so that the first light beam and the second light beam are counter-propagating and both focused to the spatial point. | 05-12-2011 |
| 20110122416 | TURBIDITY SUPPRESSION BY OPTICAL PHASE CONJUGATION USING A SPATIAL LIGHT MODULATOR - A detector of light transmitted through a turbid medium, comprising: one or more Digital Optical Phase Conjugation (DOPC) devices, wherein the DOPC devices include (1) a sensor for detecting input light that has been transmitted through the turbid medium and inputted on the sensor; and (2) a spatial light modulator (SLM) for outputting, in response to the input light detected by the sensor, output light that is an optical phase conjugate of the input light. | 05-26-2011 |
| 20110309267 | ITERATIVE TIME-REVERSAL ENHANCED TRANSMISSION SOLVING APPROACH - A method, apparatus, and article of manufacture for irradiating a sample with electromagnetic (EM) radiation. A number of passes of EM radiation through a sample are formed and/or selected, wherein the EM radiation in each of the passes comprises (1) input EM radiation incident on the sample, and (2) transmitted EM radiation exiting the sample formed from the input EM radiation that is transmitted through the sample. A phase conjugate of the transmitted EM radiation is used as the input EM radiation in a next pass of the EM radiation. The number of passes results in one or more EM fields of the input EM radiation having at least a threshold transmittance through the sample. | 12-22-2011 |
Mingwu Cui, Lexington, KY US
| Patent application number | Description | Published |
|---|---|---|
| 20110289836 | USE OF CHLORATE, SULFUR OR OZONE TO REDUCE TOBACCO SPECIFIC NITROSAMINES - A method is provided for reducing levels of tobacco specific nitrosamines (TSNA) in tobacco during barn curing. The method includes contacting tobacco with chlorate, sulfur, ozone or combinations thereof in amounts effective for controlling or reducing bacterial an/or fungal populations on or in tobacco. | 12-01-2011 |
Ning Cui, Lyndhurst, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20080241678 | ELECTROCHEMICAL CELL HAVING LOW VOLUME COLLECTOR ASSEMBLY - A low volume collector assembly and an electrochemical cell employing a collector assembly are provided. The electrochemical cell includes an electrically conductive can having inner and outer electrodes disposed therein. The cell also includes a collector assembly assembled to an open end of the can to provide closure to the open end of the can. The collector assembly includes a seal and a cover assembled to the seal to provide a sealed closure to the open end of the can. The cover includes an integrally formed current collector portion that contacts one end of the inner electrode. The cover serves as a current collector and also serves as a contact terminal of the cell. | 10-02-2008 |
Qingzhou Cui, Lowell, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120015211 | METHODS FOR THE FABRICATION OF NANOSTRUCTURES - The present invention relates to methods of fabricating nanostructures using a replacement reaction. In a preferred embodiment, metal particles in an inert atmosphere undergo a replacement reaction to form a layer on the metal particle which is removed to form a high surface area nanostructure. A preferred embodiment includes the fabrication of heater elements, powders and heater assemblies using the nanostructures. | 01-19-2012 |
Qiu Cui, Madison, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20090192725 | METHOD AND SYSTEM FOR DETERMINING COMPOUND CONCENTRATIONS IN A MIXTURE - A method of determining a concentration level of a compound in a mixture is provided. A plurality of compounds are identified in the mixture based on intensity peaks identified from NMR data generated from the mixture. A compound is selected from the identified plurality of compounds for a concentration determination. A concentration equation associated with the selected compound is determined. A first peak associated with the selected compound is selected from the NMR data. The selected first peak does not overlap with a peak associated with another compound of the identified plurality of compounds. An intensity value associated with the selected first peak is determined. A concentration of the selected compound in the mixture is calculated using the determined concentration equation and the determined intensity value. | 07-30-2009 |
Tao Cui, Durham, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100067396 | OPTIMIZING THROUGHPUT IN A WIRELESS COMMUNICATION SYSTEM - A method for optimizing throughput in a wireless communication system is disclosed. A target metric is estimated based on previous acknowledgment data. A channel quality indicator offset is determined based on the target metric. A channel quality indicator is adjusted based on the channel quality indicator offset. The channel quality indicator indicates the quality of a wireless transmission channel. | 03-18-2010 |
| 20110051831 | UNIFIED ITERATIVE DECODING ARCHITECTURE USING JOINT LLR EXTRACTION AND A PRIORI PROBABILITY - Certain aspects of the present disclosure relate to a method and an apparatus for unified iterative demodulation-decoding that can be employed in both multiple-input multiple-output (MIMO) and non-MIMO wireless systems. | 03-03-2011 |
| 20110051860 | ITERATIVE DECODING ARCHITECTURE WITH HARQ COMBINING AND SOFT DECISION DIRECTED CHANNEL ESTIMATION - Certain aspects of the present disclosure relate to a method for iterative decoding with re-transmissions of data and to a method for iterative decoding with soft decision directed channel estimation. | 03-03-2011 |
Wanxing Cui, Norcross, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20080268013 | Polyethylene Oxide Polymers Including Anti-Inflammatory Glycodendrons - Poly(ethylene oxide) (PEO) glycodendrimers can serve as multivalent inhibitors of selectin-mediated leukocyte recruitment regulating inflammatory response. Disclosed are compounds and methods relating to functionalized branched glycopolymers. In embodiments, the compounds are capable of modifying cell adhesion events and inflammatory conditions. In a particular embodiment, a multi-arm PEO polymer with sulfated lactose end groups can specifically inhibit interactions involving L-selectin. Also disclosed are methods of synthetic preparation and use. | 10-30-2008 |
Weihong Cui, Northampton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100180940 | Photovoltaic Module With Stabilized Polymer - The present invention provides a photovoltaic device comprising metal and a poly(vinyl butyral) layer that incorporates a suitable amount of 1H-benzotriazole. When electrical bias is applied to the photovoltaic device, 1H-benzotriazole forms a barrier layer at the metal/poly(vinyl butyral) interface, which, for example, unexpectedly virtually eliminated the yellowing of poly(vinyl butyral) in photovoltaic devices comprising silver components. | 07-22-2010 |
Xiaojiang Cui, Pearland, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20110150979 | METHODS FOR DIAGNOSIS, PROGNOSIS AND TREATMENT OF PRIMARY AND METASTATIC BASAL-LIKE BREAST CANCER AND OTHER CANCER TYPES - In one embodiment, a method of theranostic classification of a breast cancer tumor is provided, comprising obtaining a breast cancer tumor sample from a subject, detecting an expression level of FOXC1, comparing the expression level of FOXC1 to a predetermined cutoff level, and classifying the breast cancer tumor sample as belonging to a theranostic basal-like breast cancer tumor subtype or a theranostic hybrid basal-like breast cancer tumor subtype when the expression level of FOXC1 is higher than the predetermined cutoff level. In other embodiments, methods for predicting a prognosis of a basal-like breast cancer and methods of treating a basal-like breast cancer are provided, | 06-23-2011 |
Xiaoli Cui, Memphis, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20110256546 | METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF CANCER RESISTANT TO ANAPLASTIC LYMPHOMA KINASE (ALK) KINASE INHIBITORS - Compositions and methods for the diagnosis and treatment of a cancer that is resistant to at least one anaplastic lymphoma kinase (ALK) kinase inhibitor are provided herein. The present invention is based on the discovery of mutations within ALK that confer resistance to at least one ALK kinase inhibitor. Polynucleotides and polypeptides having at least one ALK inhibitor resistance mutation are provided and find use in methods and compositions useful in the diagnosis, prognosis, and/or treatment of diseases associated with aberrant ALK activity, more particularly, those that are resistant to at least one ALK kinase inhibitors. Methods and compositions are also provided for the identification of agents that can inhibit the kinase activity and/or reduce the expression level of the ALK resistance mutants. | 10-20-2011 |
Xiaoxia Cui, Saint Louis, MO US
| Patent application number | Description | Published |
|---|---|---|
| 20090142838 | Methods for expressing rnp particles in eukaryotic cells - Provided herein are nucleic acid constructs and methods for producing or enhancing the production of group II intron RNP particles in eukaryotic cells. The present methods comprise introducing at least one nucleic acid construct comprising a nucleic acid encoding a modified or wild type group II intron RNA and a wild-type or modified group II intron-encoded protein into the eukaryotic cell, and maintaining the cell under conditions that allow for expression of the group II intron RNA and the group II intron-encoded protein in the cell. The nucleic acid encoding the group II intron RNA is operably linked to an RNA polymerase I, an RNA polymerase II, or an RNA polymerase III promoter, and the nucleic acid encoding the group II intron-encoded protein is operably linked to an RNA polymerase II promoter. In certain embodiments, a subcellular localization signal is attached to the group II intron-encoded protein. | 06-04-2009 |
Xinyan Cui, Wexford, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20090005667 | ELECTRODE SYSTEMS, DEVICES AND METHODS - An electrode system include a flowable and cohesive surface contact element comprising a hydrophilic polymer swollen with an electrolyte fluid, the contact element having a Q′ ratio of at least 5 as defined by the equation | 01-01-2009 |
| 20090012446 | DEVICES, SYSTEMS AND METHODS FOR RELEASE OF CHEMICAL AGENTS - An electrode system includes at least one electrically conductive element to effect at least one of (a) delivery an electrical signal to living cells in the vicinity of the electrically conductive element or (b) measurement of an electrical signal from living cells in the vicinity of the electrically conductive element. The electrically conductive element includes a first conductive polymer which includes at least a first chemical agent to affect activity of the living cells. The first chemical agent is associated with the conductive polymer and is releasable from the first conductive polymer to interact with the living cells upon application of a first electrical potential to the electrically conductive element. As used herein, reference to a first electrical potential includes reference to a range or electrical potentials suitable to effect release of the chemical agent | 01-08-2009 |
Xiuhua Cui, Pearland, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20110282018 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR - The present invention generally relates to a process that selectively polymerizes ethylene in the presence of an alpha-olefin, and to a metal-ligand complex (precatalyst) and catalyst useful in such processes, and to related compositions. The present invention also generally relates to ligands and intermediates useful for preparing the metal-ligand complex and to processes of their preparation. | 11-17-2011 |
Yan Cui, Greenville, SC US
| Patent application number | Description | Published |
|---|---|---|
| 20100059573 | PROCESS OF FILLING OPENINGS IN A COMPONENT - A process for filling openings, including blind holes, through-holes, and cavities, in high temperature components. The process entails forming a powder mixture by mixing particles of at least a base alloy and a second alloy that contains a sufficient amount of a melting point depressant to have a lower melting temperature than the base alloy. The powder mixture is combined with a binder and compacted to form a compacted preform, which is then heated to remove the binder and form a rigid sintered preform. The sintered preform is produced, or optionally is further shaped, to have a cross-sectional shape and dimensions to achieve a clearance of up to 200 micrometers with the opening, after which the preform is placed in the opening and diffusion bonded within the opening to form a brazement comprising the particles of the base alloy dispersed in a matrix formed by the second alloy. | 03-11-2010 |
| 20110076151 | METHOD AND SYSTEM FOR FOCUSED ENERGY BRAZING - A method and system that includes generation of an energy beam. The energy beam may be generated from a focused energy source. Additionally, the energy beam may be directed towards a pre-sintered preform. The pre-sintered preform may be made of a braze material and may seal a hole that may be located in a turbine component. | 03-31-2011 |
Yan Cui, Greer, SC US
| Patent application number | Description | Published |
|---|---|---|
| 20110024393 | PROCESS OF CLOSING AN OPENING IN A COMPONENT - A process for closing an opening in a surface of a component, and components formed thereby. The process entails forming a channel in the component surface so that the channel at least partially surrounds an opening at the component surface. An alloy is then deposited in the channel to form a crack-free deposit in the channel. A step is then machined that intersects the opening and is at least partially formed in the deposit. The step defines a recess that is at least partially surrounded by a peripheral portion of the deposit and has a surface recessed into the component surface. A cap is placed in the recess and welded to the peripheral portion of the deposit to define a weld joint that completely closes the opening. The surface of the weld joint is then machined to form a machined surface that is substantially flush with the component surface. | 02-03-2011 |
Yi Cui, Urbana, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20100115628 | DIGITAL RIGHTS MANAGEMENT SCHEME FOR AN ON-DEMAND DISTRIBUTED STREAMING SYSTEM - A DRM scheme that may be optionally invoked by the owner. With the DRM protection turned on, the media is encrypted before it is distributed in a P2P network, and is decrypted prior to its use (play back). The peers may still efficiently distribute and serve without authorization from the owner. Nevertheless, when the media is used (played back), the client node must seek proper authorization from the owner. The invention further provides a hierarchical DRM scheme wherein each packet of the media is associated with a different protection level. In the hierarchical DRM scheme of the invention there is usually an order of the protection level. As a result, in one embodiment of the invention, the decryption key of a lower protection layer is the hash of the decryption key at the higher protection level. That way, a user granted access to the high protection layer may simply hold a single license of that layer, and obtain decryption keys of that layer and below. The invention further provides for a process for managing digital rights to a scalable media file wherein a different encryption/decryption key is used to encrypt each truncatable media packet with a base layer without requiring additional storage space to store the key. | 05-06-2010 |
Yi Cui, Allston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100243990 | NANOSENSORS - Electrical devices comprised of nanowires are described, along with methods of their manufacture and use. The nanowires can be nanotubes and nanowires. The surface of the nanowires may be selectively functionalized. Nanodetector devices are described. | 09-30-2010 |
Yunxing Cui, Carmel, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20110289620 | AAD-1 EVENT DAS-40278-9, RELATED TRANSGENIC CORN LINES, EVENT-SPECIFIC IDENTIFICATION THEREOF, AND METHODS OF WEED CONTROL INVOLVING AAD-1 - This invention relates in part to plant breeding and herbicide tolerant plants. This invention includes a novel aad-1 transformation event in corn plants comprising a polynucleotide sequence, as described herein, inserted into a specific site within the genome of a corn cell. In some embodiments, said event/polynucleotide sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. Additionally, the subject invention provides assays for detecting the presence of the subject event in a sample (of corn grain, for example). The assays can be based on the DNA sequence of the recombinant construct, inserted into the corn genome, and on the genomic sequences flanking the insertion site. Kits and conditions useful in conducting the assays are also provided. The subject invention also includes related methods of controlling weeds. | 11-24-2011 |
Yunxing C. Cui, Carmel, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20110154529 | INDUCED CHROMOSOME DOUBLING IN PLANTS - Methods to generate doubled haploid plants and plant components using low mammalian toxicity chromosome doubling agents are disclosed. Chromosome doubling agents provide low mortality rates and higher chromosome doubling rate in plants. | 06-23-2011 |
| 20120110688 | AAD-12 EVENT 1606 AND RELATED TRANSGENIC SOYBEAN LINES - This invention relates to soybean event pDAB4472-1606 (Event 1606). This invention includes a novel aad-12 transformation event in soybean plants comprising a polynucleotide sequence, as described herein, inserted into a specific site within the genome of a soybean cell. This invention also relates in part to plant breeding and herbicide tolerant plants. In some embodiments, said event/polynucleotide sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. | 05-03-2012 |
Yushun Cui, Ann Arbor, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20110117309 | BIOMIMETIC TENDON-REINFORCED (BTR) COMPOSITE MATERIALS - Biomimetic tendon-reinforced” (BTR) composite structures feature improved properties including a very high strength-to-weight ratio. A basic structure comprises a plurality of spaced-apart stuffer members, each having a first end and a second end defining a length. A plurality of tendon elements interconnect with the first and second ends of the stuffer members in alternating fashion, such that the tendon elements criss-cross each other between the stuffer members. A first panel is bonded or attached to the first ends of the stuffer members, and a second panel is bonded or attached to the second ends of the stuffer members. In the preferred embodiments, the first panel, the second panel, or both the first and second panels are curved. An efficient manufacturing process based upon hollow stuffers and tendon elements in the form of bent wires is also disclosed. | 05-19-2011 |
| 20110168313 | ULTRALIGHTWEIGHT RUNFLAT TIRES BASED UPON NEGATIVE POISSON RATIO (NPR) AUXETIC STRUCTURES - Negative Poisson's ratio (NPR) or auxetic are used to make lightweight wheels and runflat tires. The NPR tires can be tailored and functionally-designed to optimally meet the runflat requirements for both military and commercial vehicles. NPR-runflat tires may be fabricated using standard materials and simple manufacturing processes, resulting in low-cost and high-volume production. In preferred embodiments the runflat tire designs are fully compatible with Central Tire Inflation Systems (CTIS), while providing a performance equivalent to current military vehicle solutions but at half the weight. An auxetic wheel according to the invention comprises a line defining an axis of rotation; and a plurality of concentric rings of unit cells surrounding the axis, each unit cell being constructed of a plurality of members defining a Negative Poisson's Ratio (NPR) structure. The outermost ring of unit cells is arranged to facilitate rolling terrain contact, such that the stiffness of the structure in the localized region of loading due to terrain contact increases as the wheel rotates. A layer of material may be disposed between the concentric rings of unit cells which in preferred embodiments comprise a plurality of nested-V shapes. A cover may be provided over the outermost ring of unit cells forming a tire which may, or may not, be inflated. | 07-14-2011 |
Zheng Cui, Winston-Salem, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20120107293 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER - A method of treating cancer comprises: (a) providing allogenic or autologous white blood cells from a suitable donor; and then (b) administering the white blood cells to the subject in an amount effective to treat the cancer. Preferably the white blood cells comprise innate immune cells. Preferably the white blood cells comprise less than 10% by number of cytotoxic T lymphocytes. Preferably the white blood cells, or more particularly the innate immune cells, are preselected in vitro to kill cancer cells in vitro (for example, by collecting white blood cells from the patient and determining that the white blood cells kill cancer cells in vitro before and thereby pre-selecting the donor, before collecting a subsequent population of cells from the donor for administration). | 05-03-2012 |
Zhi Cui, Marieta, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20110093732 | APPARATUS AND METHOD FOR PROVIDING NETWORK COMMUNICATIONS - A system that incorporates teachings of the present disclosure may include, for example, a Power Over Ethernet (PoE) device (PD) having a controller to receive signals over a first cable having twisted pair wires from at least one of a network element and a gateway where the network element is associated with a service provider where the gateway is associated with a premises and where the service provider provides network communications to the premises, adjust the signals, transmit the adjusted signals over a second cable having twisted pair wires to at least one of the network element and the gateway, and receive power from at least one of the network element and the gateway, where the power is received over at least one of the first and second cables, where the power is received according to PoE protocol, and where the PD is positioned between the network element and the gateway. Other embodiments are disclosed. | 04-21-2011 |
Zhi Cui, Marietta, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20090103545 | METHODS, SYSTEMS, AND COMPUTER PROGRAM PRODUCTS FOR MANAGING QUALITY OF SERVICE IN A PASSIVE OPTICAL NETWORK - Quality of Service (QoS) can be managed in a network that uses time division access, such as a Passive Optical Network (PON), by supporting provisioning of at least two scheduling precedence levels in the PON, none of the at least two precedence levels being associated with a fixed or assured bandwidth traffic type in the PON, but having a bandwidth precedence and/or proportion relationship to each other. | 04-23-2009 |
| 20100103947 | DISTRIBUTED DIGITAL SUBSCRIBER LINE ACCESS MULTIPLEXERS TO INCREASE BANDWIDTH IN ACCESS NETWORKS - Example distributed DSLAMs to increase bandwidth in access networks are disclosed. An example DSLAM comprises a first distribution cable segment to couple an SAI to a first pedestal and to transport user data, a second distribution cable segment to couple the first pedestal to a second pedestal and to transport a first portion of the user data from the first pedestal to the second pedestal, the second cable segment comprising a pair of DSL-based signals bonded together, a drop cable to couple the first pedestal to a customer premises and to transport a second portion of the user data to the customer premises, and a switch at the first pedestal to route the first portion of the user data between the first and second cable segments and to route the second portion of the user data between the first cable segment and the drop cable. | 04-29-2010 |
| 20100119235 | METHODS AND APPARATUS TO DEPLOY FIBER OPTIC BASED ACCESS NETWORKS - Methods and apparatus to deploy fiber optic based access networks are disclosed. An example access network comprises a first fiber optic cable segment to couple an optical access head-end to a first pedestal and to transport user data, a second fiber optic cable segment to couple the first pedestal to a second pedestal and to transport a first portion of the user data to the second pedestal, a drop cable segment to couple the first pedestal to a customer premises and to transport a second portion of the user data to the customer premises, and a switch at the first pedestal to route the first portion of the user data between the first and second fiber optic cable segments and to route the second portion of the user data between the first fiber optic cable segment and the drop cable segment. | 05-13-2010 |
| 20110026930 | METHODS AND APPARATUS TO UPGRADE COMMUNICATION SERVICES IN SUBSCRIBER DISTRIBUTION AREAS - Example methods and apparatus to upgrade communication services in subscriber distribution areas are disclosed. A disclosed example method involves installing an optical network unit communicatively coupled to an optical line terminal serving a subscriber distribution area communicatively coupled to the optical line terminal. The optical network unit includes a first subscriber downlink interface to serve a first subscriber premises and a second subscriber downlink interface to serve a second subscriber premises. A first communication service is provided to the first subscriber premises via a first electrically conductive medium communicatively coupled to the first subscriber downlink interface via a first removably attachable subscriber downlink module. A second communication service is provided to the second subscriber premises via a second electrically conductive medium communicatively coupled to the second subscriber downlink interface via a second removably attachable subscriber downlink module. In response to receiving a request to upgrade the first communication service, the first removably attachable subscriber downlink module is replaced with a third removably attachable subscriber downlink module, an optical transmission medium is connected between the third removably attachable subscriber downlink module and the first subscriber premises while retaining the second electrically conductive medium communicatively coupled to the second subscriber downlink interface to provide the second communication service to the second subscriber premises. | 02-03-2011 |