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Craig, GB
Andrew Craig, Letchworth Garden City GB
| Patent application number | Description | Published |
|---|---|---|
| 20100113289 | Method and system for non-competitive copy number determination by genomic hybridization DGH - A method and system for determining a copy number of one or more nucleic acid sequences in a test sample are provided. A solid surface with a plurality of probe sets labeled with a first detectable label material bound to the solid surface is provided. The labeled probes are contacted with one or more nucleic acid molecules of the test sample, under conditions suitable for hybridization, so as to form a modified solid surface. The one or more nucleic acid molecules is/are labeled with a second detectable label material. The modified solid surface is scanned to obtain first and second data, which is then mathematically transformed so as to determine the copy number of one or more nucleic acid sequences in the test sample relative to the copy number of the one or more different nucleic acid sequences in the test sample or a reference genome. | 05-06-2010 |
| 20110230362 | COMPARATIVE GENOMIC HYBRIDIZATION ARRAY METHOD FOR PREIMPLANTATION GENETIC SCREENING - A method for determining the presence of a copy number imbalance in genomic DNA of a test sample is provided. The method can separately measure hybridization of a single test sample to a first hybridization array and hybridization of a plurality of reference samples to a plurality of other, respective test arrays. A determination of copy number can be based on the best fit reference array, relative to the test array. The best fit can be determined based on the closest or most similar signal-to-noise ratio of the measured signals. | 09-22-2011 |
Andrew Simon Craig, Kent GB
| Patent application number | Description | Published |
|---|---|---|
| 20110245496 | Quinazoline Salt Compounds - Salts of 4-quinazolineamines are described as well as methods of using the same in the treatment of disorders characterized by aberrant erbB family PTK activity. | 10-06-2011 |
Anthony Duncan Craig, Hertfordshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20110110401 | MODULAR DIGITAL PROCESSING SYSTEM FOR TELECOMMUNICATIONS SATELLITE PAYLOADS - A telecommunications satellite payload processing system having one or more identical generic integrated processor modules is provided. The number of integrated processor modules can be selected in accordance with the antenna and bandwidth characteristics of a specified mission uplink and downlink in relation to the characteristics of the integrated processor module. | 05-12-2011 |
Anthony Duncan Craig, Hitchin GB
| Patent application number | Description | Published |
|---|---|---|
| 20100172437 | Signal pre-processor for an amplifying system - A signal pre-processor, for at least partially correcting non-linear performance of a high power amplifier (“HPA”), operates on an over-sampled signal in complex form in the digital domain. By converting the over-sampled signal to amplitude values, the pre-processor is enabled to apply correction values, based on the amplitude values, which correction values incorporate both amplitude and phase correction in respect of distortion generated in the HPA. The use of an over-sampled signal allows out-of-band correction values to be applied to correct out-of-band distortion arising in the signal processing path, for instance in the linearization process itself. The out-of-band distortion can otherwise alias back in-band, creating noise at the HPA. | 07-08-2010 |
| 20100220646 | COMPENSATION APPARATUS - There is provided an apparatus for a satellite communication system comprising: a processor to determine at least one out of a phase offset for a frequency channel of a plurality of frequency channels demultiplexed from a carrier to compensate for group delay variation within the carrier and a gain offset for the frequency channel to compensate for gain variation within the carrier, wherein the processor is further configured to apply the at least one out of the determined phase offset and gain offset to the frequency channel before the carrier is reformed from said plurality of frequency channels. The invention therefore provides a way of digitally compensating for any undesired gain and group delay introduced by, for example, analogue components such as filters in the satellite communication system. | 09-02-2010 |
| 20100231442 | SATELLITE BEAM-POINTING ERROR CORRECTION IN DIGITAL BEAM-FORMING ARCHITECTURE - A digital method of determining and correcting beam-pointing for a communications spacecraft that has a digital beam-forming architecture for defining multiple spot transmit and receive beams, the antenna system of the spacecraft including a receive antenna (DRA, AFR) having antenna elements providing respective antenna element signals, and wherein at least one of the uplink signals to the spacecraft includes a beacon signal, | 09-16-2010 |
| 20100232350 | INTERFERENCE REMOVAL - Apparatus for a satellite communication system, comprising: a processor arrangement to monitor a plurality of frequency channels demultiplexed from a signal comprising one or more carriers, identify at least one frequency channel of the plurality of frequency channels comprising interference and remove the at least one identified frequency channel before the one or more carriers are reformed. By removing the frequency channels comprising interference, the signal-to-noise ratio of a carrier can be improved. Also, if the interference occurs within a carrier, the carrier is usable as long as the removed frequency channels are considerably narrower than the carrier. | 09-16-2010 |
Antony Duncan Craig, Hitchin GB
| Patent application number | Description | Published |
|---|---|---|
| 20100123621 | Active interference suppression in a satellite communication system - The invention relates to active interference suppression in a satellite communication system, particularly but not exclusively to an apparatus and method for using active interference suppression in order to suppress co-channel interference between user signals in the communication system. The communication system includes a receive or transmit antenna having a plurality of antenna elements, each antenna element associated with a respective antenna element signal. The method includes the steps of calculating complex weighting values for one or more of a plurality of beam signals, adjusting the beam signals in accordance with the calculated complex weighting values and cancelling co-channel interference in at least one of the beam signals using the one or more adjusted derived beam signals to provide an interference suppressed output signal. The complex weighting values can be calculated based on a constant modulus algorithm. | 05-20-2010 |
| 20100221997 | Active interference suppression in a satellite communication system - The invention relates to active interference suppression in a satellite communication system, particularly but not exclusively to an apparatus and method for using active interference suppression in order to suppress co-channel interference between user signals in the communication system. The communication system includes a receive or transmit antenna having a plurality of antenna elements, each antenna element associated with a respective antenna element signal. The method includes the steps of calculating complex weighting values for one or more of a plurality of beam signals, adjusting the beam signals in accordance with the calculated complex weighting values and cancelling co-channel interference in at least one of the beam signals using the one or more adjusted derived beam signals to provide an interference suppressed output signal. The complex weighting values can be calculated based on a constant modulus algorithm. | 09-02-2010 |
Antony Duncan Craig, Hertfordshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20100194629 | SYSTEM FOR SIMPLIFICATION OF RECONFIGURABLE BEAM-FORMING NETWORK PROCESSING WITHIN A PHASED ARRAY ANTENNA FOR A TELECOMMUNICATIONS SATELLITE - A telecommunications satellite having a phased array antenna, wherein the beam-forming function within the phased array is simplified by partitioning it into two stages, in which the sub-array stage relates to a fixed, or infrequently changed, set of overlapping sub-arrays and the main stage provides the main pattern reconfiguration, typically in the form of multiple reconfigurable spot beams within a defined coverage region. The key advantage lies in the significant reduction in number of second stage beam-forming control points (at which independent amplitude and phase is applied) when compared with a conventional phased array (where amplitude and phase control is applied for each element of the array). The sub-array stage beam-forming may be implemented in analogue technology. The main beam-former may be implemented in digital technology, where the key processing functions of A/D or D/A conversion, frequency (de)multiplexing and digital beam-forming all scale with the number of control points. | 08-05-2010 |
Beverley Craig, Culmore GB
| Patent application number | Description | Published |
|---|---|---|
| 20110007426 | TRAPEZOIDAL BACK BIAS AND TRILAYER READER GEOMETRY TO ENHANCE DEVICE PERFORMANCE - A magnetoresistive sensor having a trilayer sensor stack with two ferromagnetic freelayers separated by a nonmagnetic spacer layer is disclosed. The sensor is biased with a back biasing magnet adjacent a back of the trilayer sensor. The back biasing magnet, the trilayer sensor stack, or both have substantially trapezoidal shapes to enhance the biasing field and to minimize noise. In some embodiments, the trilayer sensor or back bias magnet have a shape designed to stabilize a micromagnetic “C” shape or concentrate magnetic flux in the trilayer sensor stack. | 01-13-2011 |
Duncan Craig, Norfolk GB
| Patent application number | Description | Published |
|---|---|---|
| 20110111108 | COMPOSITIONS AND METHOD FOR ASSISTING SWALLOWING - A method of assisting a subject to swallow an object such as a solid pharmaceutical dosage form comprises providing on the object an at least partial surface covering comprising a lubricating edible gel composition. | 05-12-2011 |
Eona Hunter Craig, Glasgow GB
| Patent application number | Description | Published |
|---|---|---|
| 20090071052 | Slot sided picture frame for display of 2D and 3D pictures and artwork - This is a picture frame with one open side, a vision panel in front and hanging system at the back. This frame displays 2 and 3 dimensional pictures and artwork. The design includes a slot feature for receiving paper and card without the need for opening the frame front or back. The range of frames can display single and multiple artworks at the same time, in portrait or landscape orientations. | 03-19-2009 |
Iain Craig, London GB
| Patent application number | Description | Published |
|---|---|---|
| 20080275750 | Method and system for processing and communicating corporate action events - Providing for processing and communicating corporate action events and any associated elections. These systems and methods enable straight through processing of corporate action events, including events requiring the election of optional events by a security holder. These systems and methods would receive and process data regarding corporate action events. These data would be processed and notifications sent to affected security holders. For events that require the security holder to make an election, the systems and methods may receive and process those elections. The elections would then be used to implement the resulting outcome. An exemplary embodiment of the present invention would employ XML messaging in the automation process. The systems and methods may also include a process that can identify and, if possible, fix an exception to a message or data stream. Also, an asset servicing portal may be used for communicating notifications and elections. | 11-06-2008 |
Ian Muir Craig, Broxbum GB
| Patent application number | Description | Published |
|---|---|---|
| 20120020840 | DETECTION SYSTEM - A system for detecting small quantities of agent such as DNA in a larger volume of substance is disclosed. The system includes a radiation emitter arranged so as to emit radiation on to a quantity of substance containing the agent. The incident radiation excites the agent causing it to emit radiation detectable by suitable detection means. The incident and emitted radiation are directed by a light guide that also acts so as to contain the substance being monitored. | 01-26-2012 |
James William Craig, Wakefield GB
| Patent application number | Description | Published |
|---|---|---|
| 20090108718 | KITCHEN UNIT ARRANGEMENT - A kitchen unit arrangement ( | 04-30-2009 |
Roger K. Craig, Cheshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20080255002 | Genetic manipulation method - A method of inducing transposition in a transgenic embryo, sperm and egg is described, comprising the steps of (a) generating a first adult transgenic organism comprising within its genome one or more copies of a transposon; (b) generating a second adult transgenic organism comprising within its genome one or more copies of a gene encoding a transposase cognate for the transposon and/or a sequence capable of regulating expression of the gene encoding the transposase; (c) crossing the first adult transgenic organism with the second transgenic adult organism to provide a progeny which comprises, in the genome of one or more of its cells, both (i) one or more copies of the transposon and (ii) a gene encoding a transposase cognate for the transposon, wherein the gene encoding the transposase is under the control of one or more inducible regulatory sequences which permit expression of the transposase, and (d) expressing the gene encoding the transposase in the embryo, sperm or egg to cause mobilisation of the transposon within a portion of the tissues or cells of the progeny. Using the method, mobilisation of a transposon can advantageously be induced at predetermined stages of development of an embryo, sperm or egg and the mutated gene of a single cell may be replicated in subsequent cell divisions, resulting in groups of cells which are essentially homogenous for the transposed gene. | 10-16-2008 |
Roger Kingdon Craig, Cheshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20090169548 | BINDING MOLECULES - The present invention relates to the manufacture of mono, di and multivalent polypeptide binding complexes, also mono, di or multispecific polypeptide binding complexes and uses thereof. The invention also relates to the manufacture and use of a diverse repertoire of antigen specific VH binding domains derived from phage display libraries, transgenic animals or natural sources. Preferably the VH binding domains and the dimerisation domains comprise human sequences. The polypeptide binding complexes comprise homo or heterodimerisation domains with four antigen binding [VH] domains fused at the amino and carboxyl termini of the dimerisation domains preferably using natural hinge or linker peptides. Where the polypeptide binding complexes lack CH2-CH3 effector functions they are preferably less than 120 kDa in size. Routes of manufacture are described herein. | 07-02-2009 |
| 20090285805 | Binding molecules - The present invention relates to the manufacture of a diverse repertoire of functional heavy chain-only antibodies that undergo affinity maturation, and uses thereof. The invention also relates to the manufacture and use of a diverse repertoire of class-specific heavy chain-only antibodies and to the manufacture and use of multivalent polypeptide complexes with antibody heavy chain functionality, preferably antibody heavy chain binding functionality, constant region effector activity and, optionally, additional effector functions. The present invention also relates to a method of generation of fully functional heavy chain-only antibodies in transgenic mice in response to antigen challenge. In particular, the present invention relates to a method for the generation of human antigen-specific, high affinity, heavy chain-only antibodies of any class, or mixture of classes and the isolation and expression of fully functional VH antigen-binding domains. | 11-19-2009 |
| 20110314563 | ANTIBODY PRODUCTION - A non-human mammal containing an endogenous lambda light chain gene locus, an endogenous kappa light chain gene locus and an endogenous heavy chain gene locus, each of which can re-arrange so that immunoglobulin heavy and light chain genes are formed and expressed in B-cells following antigen challenge but said loci have been mutated so that the ability to form functional immunoglobulin tetramers comprising re-arranged heavy and light chains produced from said mutated loci has been substantially reduced or eliminated. | 12-22-2011 |
Roger Kingdon Craig, Sandbach GB
| Patent application number | Description | Published |
|---|---|---|
| 20100197897 | BINDING MOLECULES - The present invention relates to the manufacture of a diverse repertoire of functional heavy chain-only antibodies that undergo affinity maturation, and uses thereof. The invention also relates to the manufacture and use of a diverse repertoire of class-specific heavy chain-only antibodies and to the manufacture and use of multivalent polypeptide complexes with antibody heavy chain functionality, preferably antibody heavy chain binding functionality, constant region effector activity and, optionally, additional effector functions. | 08-05-2010 |
| 20100216974 | BINDING MOLECULES - The present invention relates to the manufacture of a diverse repertoire of functional heavy chain-only antibodies that undergo affinity maturation, and uses thereof. The invention also relates to the manufacture and use of a diverse repertoire of class-specific heavy chain-only antibodies and to the manufacture and use of multivalent polypeptide complexes with antibody heavy chain functionality, preferably antibody heavy chain binding functionality, constant region effector activity and, optionally, additional effector functions. | 08-26-2010 |
| 20110118444 | BINDING MOLECULES - The present invention relates to the manufacture of a diverse repertoire of functional heavy chain-only antibodies that undergo affinity maturation, and uses thereof. The invention also relates to the manufacture and use of a diverse repertoire of class-specific heavy chain-only antibodies and to the manufacture and use of multivalent polypeptide complexes with antibody heavy chain functionality, preferably antibody heavy chain binding functionality, constant region effector activity and, optionally, additional effector functions. | 05-19-2011 |
Stewart Craig, Falkirk GB
| Patent application number | Description | Published |
|---|---|---|
| 20100286570 | WEIGHT DISTRIBUTION DETERMINATION APPARATUS - An apparatus ( | 11-11-2010 |