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Couvreur, FR

Laurence Couvreur, Paris FR

Patent application numberDescriptionPublished
20090306276USE OF COMPOSITE MATERIALS BASED ON CARBON NANOTUBES AS THICKENING AGENTS FOR AQUEOUS SOLUTIONS - The present invention relates to the use of composites based on carbon nanotubes as viscosity enhancers for aqueous solutions, characterized in that said composite comprises carbon nanotubes (CNTs) and at least one hydrophilic (co) polymer.12-10-2009
20100069577COPOLYMERS BASED ON METHACRYLATE UNITS, PREPARATION METHOD THEREOF AND USE OF SAME - The invention relates to a method for preparing a copolymer having a backbone based on methacrylate units, comprising a step involving the polymerization of one or more precursor methacrylate monomers of said units in the presence of: a polymerization initiator; at least RAFT-type transfer agent which can generate a primary radical; and at least one comonomer selected from among styrene monomers and acrylate monomers. The invention also relates to the resulting copolymers capable of being obtained according to this process, in particular block copolymers, in particular block copolymers, and to the use thereof as additives for plastic materials.03-18-2010
20100255329COPOLYMERS(S) LATEX, METHOD FOR PREPARING SAME AND USE THEREOF FOR COATING PAPER AND CARTON - The invention relates to copolymer(s) latexes prepared from vinylic monomers, non-conjugated dienes and optionally comonomers, particularly acrylic ones, in the presence of at least one chain transfer agent of the following formula.10-07-2010
20110136963METHOD FOR SNYTHESIZING AMPHIPHILIC GRADIENT COPOLYMERS SOLUBLE IN AN ALKALINE MEDIUM - The present invention relates to a process for the preparation of amphiphilic gradient copolymers by Controlled Radical Polymerization in the presence of a RAFT (Reversible Addition Fragmentation Transfer) agent. The copolymers of the invention exhibit low polydispersity indices and low viscosities in solution and are readily soluble in an alkaline medium.06-09-2011
20110166282METHOD FOR PREPARING A POLYMER PARTICLE DISPERSION IN AN AQUEOUS MEDIUM - The invention relates to a process for the preparation of an aqueous dispersion of polymer particles in an aqueous medium employing a living macroinitiator requiring a reinitiation temperature of less than 100° C.07-07-2011

Patent applications by Laurence Couvreur, Paris FR

Laurence Couvreur, Pau FR

Patent application numberDescriptionPublished
20090176924PULVERULENT COMPOSITION BASED ON CARBON NANOTUBES, METHODS OF OBTAINING THEM AND ITS USES, ESPECIALLY IN POLYMERIC MATERIALS - The present invention relates to pulverulent compositions based on carbon nanotubes which exhibit an excellent dispersibility in polymer materials and can advantageously be used as reinforcing agents and/or modifiers of conducting and/or thermal properties; they can be easily incorporated in polymer matrices in the masterblend form.07-09-2009

Patrick Couvreur, Villebon Sur Yvette FR

Patent application numberDescriptionPublished
20080317666Colonic Delivery of Active Agents - Drug delivery devices that are orally administered, and that release active ingredients in the colon, are disclosed. In one embodiment, the active ingredients are those that inactivate antibiotics, such as macrolides, quinolones and beta-lactam containing antibiotics. One example of a suitable active agent is an enzyme such as beta-lactamases. In another embodiment, the active agents are those that specifically treat colonic disorders, such as Chrohn's Disease, irritable bowel syndrome, ulcerative colitis, colorectal cancer or constipation. The drug delivery devices are in the form of beads of pectin, crosslinked with calcium and reticulated with polyethyleneimine. The high crosslink density of the polyethyleneimine is believed to stabilize the pectin beads for a sufficient amount of time such that a substantial amount of the active ingredients can be administered directly to the colon. Advantageously, the amount of polyethyleneimine is sufficient to allow a substantial portion of the pectin beads to pass through the gastrointestinal tract to the colon without releasing the active agent, and is also sufficient such that the pectin beads are sufficiently degraded in the colon to release an effective amount of the active agent.12-25-2008
20090130214Gemcitabine derivatives nanoparticles - The invention concerns a 2′,2′-difluoro-2′-deoxycytidine derivative of general formula (I), wherein: R05-21-2009
20090162339GALENIC FORMULATION FOR COLON-TARGETED DELIVERY OF ACTIVE INGREDIENTS - The invention concerns multiparticulate galenic formulations for oral administration and designed for colon targeted delivery of active principles selected from the group comprising enzymes capable of inactivating macrolides and the like, enzymes capable of inactivating quinolones and β-lactamases.06-25-2009
20100160249NANOPARTICLE DERIVATIVES OF GEMCITABINE - The use of squalenic acid or a derivative thereof in formulating at least one polar active principle with a molecular weight of 100 Da or more, in the form of nanoparticles, and pharmaceutical compositions thereof.06-24-2010
20100226991SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE - The invention relates to solid organometallic hybrids with modified surface. Said solid may be used for example for the encapsulation and vectoring of molecules of interest such as active pharmaceutical agents, compounds of interest in cosmetics and markers, for example, contrast agents. Said solids show good results in terms of loading capacity in medicament agents and in biocompatibility.09-09-2010
20100305030NANOPARTICLES OF THERAPEUTIC AGENTS HAVING LOW WATER SOLUBILITY - The invention relates to a water-dispersible derivative of a therapeutic agent having a low water solubility that comprises at least one molecule of said agent covalently bonded to at least one molecule of a hydrocarbon derivative having a squalenic structure or the like. The invention further relates to corresponding nanoparticles.12-02-2010

Patent applications by Patrick Couvreur, Villebon Sur Yvette FR