| Patent application number | Description | Published |
| 20080289140 | Cyclonic Separating Apparatus - A cyclonic separating apparatus includes a first cyclonic separating unit including at least one first cyclone, a second cyclonic separating unit located downstream of the first cyclonic separating unit and including at least one second cyclone, and a third cyclonic separating unit located downstream of the second cyclonic separating unit and including a plurality of third cyclones arranged in parallel. The separation efficiency of the first cyclonic separating unit is lower than the separation efficiency of the second cyclonic separating unit and the separation efficiency of the second cyclonic separating unit is lower than the separation efficiency of the third separating unit, thus achieving a higher separation efficiency than known separation apparatus. | 11-27-2008 |
| 20090031524 | Multistage Cyclonic Separating Apparatus - A cyclonic separating apparatus includes a first cyclonic separating unit including at least one first cyclone, a second cyclonic separating unit located downstream of the first cyclonic separating unit and including a plurality of second cyclones arranged in parallel, and a third cyclonic separating unit located downstream of the second cyclonic separating unit and including a plurality of third cyclones arranged in parallel. The number of second cyclones is higher than the number of first cyclones and the number of third cyclones is higher than the number of second cyclones, providing an apparatus which achieves a higher separation efficiency than known separation apparatus. | 02-05-2009 |
| 20090288268 | SURFACE TREATING APPLIANCE - A surface treating appliance, such as a vacuum cleaner, includes a main body, a surface treating head and a support assembly. The support assembly is rotatably mounted to the main body for allowing the main body to be rolled along a surface. The support assembly also houses a component of the appliance, such as a motor for driving a surface-agitating device. Alternatively, or additionally, the support assembly may accommodate a fluid inlet for receiving fluid flow, a fluid outlet for exhausting fluid and a device for acting on the fluid flow received by the inlet such as a filter or suction apparatus. | 11-26-2009 |
| 20110061351 | MULTISTAGE CYCLONIC SEPARATING APPARATUS - A cyclonic separating apparatus includes a first cyclonic separating unit including at least one first cyclone and an annular dust collecting chamber, a second cyclonic separating unit located downstream of the first cyclonic separating unit and including at least one second cyclone and a dust collecting chamber, and a third cyclonic separating unit located downstream of the second cyclonic separating unit and including a plurality of third cyclones arranged in parallel and a dust collecting chamber. The number of third cyclones is higher than the number of second cyclones, and the dust collecting chambers of the second and third cyclonic separating units are located inside of the annular dust collecting chamber of the first cyclonic separating unit. | 03-17-2011 |
| Patent application number | Description | Published |
| 20090163487 | N-HYDROXYLSULFONAMIDE DERIVATIVES AS NEW PHYSIOLOGICALLY USEFUL NITROXYL DONORS - The invention relates to N-hydroxylsulfonamide derivatives that donate nitroxyl (HNO) under physiological conditions and are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure and ischemia/reperfusion injury. Novel N-hydroxylsulfonamide derivatives release NHO at a controlled rate under physiological conditions, and the rate of HNO release is modulated by varying the nature and location of functional groups on the N-hydroxylsulfonamide derivatives. | 06-25-2009 |
| 20110136827 | Bis-Acylated Hydroxylamine Derivatives - The invention provides certain bis-acylated hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the invention provides methods of using such compounds or pharmaceutical compositions for treating, preventing, or delaying the onset and/or develop of a disease or condition. In some embodiments, the disease or condition is selected from cardiovascular diseases, ischemia, reperfusion injury, cancerous disease, pulmonary hypertension and conditions responsive to nitroxyl therapy. | 06-09-2011 |
| 20110144067 | N-Acyloxysulfonamide and N-Hydroxy-N-Acylsulfonamide Derivatives - The invention provides certain N-acyloxysulfonamide and N-hydroxy-N-acylsulfonamide derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the invention provides methods of using such compounds or pharmaceutical compositions for treating, preventing, or delaying the onset and/or develop of a disease or condition. In some embodiments, the disease or condition is selected from cardiovascular diseases, ischemia, reperfusion injury, cancerous disease, pulmonary hypertension and conditions responsive to nitroxyl therapy. | 06-16-2011 |
| Patent application number | Description | Published |
| 20100099736 | PHENYL SUBSTITUTED MALEIMIDES AS MEDICAMENTS FOR BLOCKING DEGENERATIVE TISSUE DAMAGES BY INHIBITING MPT - The invention discloses the use of a compound of formula (I), wherein R | 04-22-2010 |
| 20110118258 | QUINAZOLIN-OXIME DERIVATIVES AS HSP90 INHIBITORS - Compounds of general formula (I); or a stereoisomers, tautomers, pharmaceutically acceptable salts, or prodrugs thereof, wherein R1, R2, R3, R4, R5, R6, R8 and R9 are as defined herein, are useful for the treatment of diseases and conditions which are mediated by excessive or inappropriate Hsp90 activity such as cancers, viral infection and inflammatory diseases or conditions. | 05-19-2011 |
| 20110183957 | CERTAIN KYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF - Certain chemical entities are provided herein. Also provided are pharmaceutical compositions comprising at least one chemical entity and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of KMO activity are described, which comprise administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include neurodegenerative disorders such as Huntington's disease. Also described are methods of treatment include administering at least one chemical entity as a single active agent or administering at least one chemical entity in combination with one or more other therapeutic agents. Also provided are methods for screening compounds capable of inhibiting KMO activity. | 07-28-2011 |
| 20110230428 | CERTAIN KYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF - Certain chemical entities are provided herein. Pharmaceutical compositions comprising at least one chemical entity and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of KMO activity are described, which comprise administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include neurodegenerative disorders such as Huntington's disease. Methods of treatment include administering at least one chemical entity as a single active agent or administering at least one chemical entity in combination with one or more other therapeutic agents. Also provided are methods for screening compounds capable of inhibiting KMO activity. | 09-22-2011 |