| Patent application number | Description | Published |
|---|
| 20090054595 | Compounding Formulations for Producing Articles from Guayule Natural Rubber - The invention disclosed herein relates to a process for making elastomeric rubber articles, and in particular, the process of producing such articles from non- | 02-26-2009 |
| 20090099327 | RAPID EXPANDED SOLVENT EXTRACTION - The present disclosure provides for a method of rapid expanded solvent extraction of biopolymers, such as rubber, from plant materials, such as guayule, using an expanded hexane solvent. As is illustrated herein, the use of the expanded hexane solvent results in a markedly more efficient and rapid extraction process over other supercritical carbon dioxide extraction systems, including those systems using a hexane cosolvent. | 04-16-2009 |
| 20090107510 | TWO-LAYER ENDOTRACHEAL TUBE CUFF FOR PREVENTION OF PNEUMONIA - A novel two-layer endotracheal tube (ETT) cuff for the prevention of pneumonia is disclosed. The disclosed two-layer ETT comprises a standard HVLP cuff covered with a second layer of elastomeric material with a sterile gel inserted between the layers. The two-layer cuff forms no folds when inflated in the trachea and prevents leakage, substantially reducing the risk for pneumonia attributable to standard ETT cuffs. | 04-30-2009 |
| 20090163689 | GUAYULE NATURAL RUBBER LATEX THIN FILM ARTICLES - The present disclosure provides for a formula and process for making elastomeric rubber thin film articles. In particular, the formula and process is a system which produces non- | 06-25-2009 |
| 20110021743 | EXTRACTION AND FRACTIONATION OF BIOPOLYMERS AND RESINS FROM PLANT MATERIALS - A method for the extraction, separation, fractionation and purification of biopolymers from plant materials using supercritical and/or subcritical solvent extractions is disclosed. Specifically, the process can be used for the separation of resins and rubber from guayule shrub ( | 01-27-2011 |
| Patent application number | Description | Published |
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| 20090162858 | Orthogonal chemical inducer of dimerization - A method for identifying a molecule as being able to bind a protein target in a cell, comprising (a) covalently bonding the molecule to trimethoprim (TMP) to form a screening molecule, (b) introducing the screening molecule into the cell which (A) expresses (i) a first fusion protein comprising a binding domain capable of binding TMP, and (ii) a second fusion protein comprising the protein target, and (B) comprises a reporter gene, wherein one of the fusion proteins comprises a DNA-binding domain and the other fusion protein comprises a transcription activation domain and wherein expression of the reporter gene is conditioned on the proximity of the DNA-binding domain to the transcription activation domain; and (c) determining whether the screening molecule binds to the first fusion protein and to the second fusion protein by determining whether the cell expresses the reporter gene, wherein expression of the reporter gene indicates that the molecule binds the protein target and wherein lack of expression of the reporter gene indicates that the molecule does not bind the protein target. | 06-25-2009 |
| 20090209038 | Cell-Mediated Directed Evolution - The present invention relates to systems which harness the molecular biology of a living cell to direct evolution of biological entities of interest. According to the invention, a host cell is engineered to facilitate mutation of a nucleic acid target corresponding to that entity and select for desirable mutants. As applied to populations of host cells, the invention provides a means to generate and contemporaneously select mutants of interest, allowing for the production of extremely diverse libraries enriched in the most ‘fit’ mutants. | 08-20-2009 |
| 20100261167 | In vivo screen using chemical inducers of dimerization - A method for identifying a molecule that binds a known target in a cell from a pool of candidate molecules, comprising: (a) covalently bonding each molecule in the pool of candidate molecules to a methotrexate moiety to form a screening molecule; (b) introducing the screening molecule into a cell which expresses a first fusion-protein comprising a binding domain capable of binding methotrexate, a second fusion protein comprising the known target, and a reporter gene wherein expression of the reporter gene is conditioned on the proximity of the first fusion protein to the second fusion protein; (c) permitting the screening molecule to bind to the first fusion protein and to the second fusion protein so as to activate the expression of the reporter gene; (d) selecting which cell expresses the reporter gene; and (e) identifying the small molecule that binds the known target. | 10-14-2010 |
