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Coquerel

Gerard Coquerel, Notre Dame De Bondeville FR

Patent application numberDescriptionPublished
20090124811Method for resolving omeprazole salts - The present invention relates to the resolution by preferential crystallization of potassium salts of racemic omeprazole which is a solvate of ethanol and/or of ethylene glycol, which consists in converting the omeprazole to the potassium salt in the form of a solvate or of a mixture of these solvates in the presence of an excess of inorganic base which is a source of potassium, the said potassium salts existing in the form of conglomerates, and in then resolving the said conglomerates, independently or simultaneously, by preferential crystallization in order to separate the two (S) and (R) enantiomers of these potassium salts of omeprazole.05-14-2009

Gerard Coquerel, Paris FR

Patent application numberDescriptionPublished
20090048449RIMONABANT MONOHYDRATE, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME - The present invention relates to rimonabant monohydrate, to the process for preparing it and to the pharmaceutical compositions containing it.02-19-2009

Gerard Coquerel, Mont Saint Aignan FR

Patent application numberDescriptionPublished
20110269798PRECURSOR PHASE AND USE THEREOF FOR PREPARING THE MAGNESIUM TETRAHYDRATE SALT OF AN OMEPRAZOLE ENANTIOMER - A precursor phase of the magnesium tetrahydrate salt of an omeprazole enantiomer, and also processes for preparing it and its use for the preparation of the magnesium tetrahydrate salt are described. Crystals of the magnesium tetrahydrate salt thus obtained, and their uses, especially in the synthesis of the dihydrate form A of the magnesium salt of the enantiomer or as medicament are also disclosed.11-03-2011

Gérard Coquerel, Boss FR

Patent application numberDescriptionPublished
20120071655PROCESS FOR ENANTIOMERIC SEPARATION OF RACEMIC DIHYDRO-1,3,5, TRIAZINES VIA PREFERENTIAL CRYSTALLIZATION - A new process for the enantiomeric separation of racemic 3,6-dihydro-1,3,5-triazine derivatives for the treatment of disorders associated with insulin-resistance syndrome, by preferential crystallization.03-22-2012

Gérard Francois Coquerel, Boos FR

Patent application numberDescriptionPublished
20090281192Process for the Preparation of and Crystalline Forms of Optical Enantiomers of Modafinil - The invention relates to a polymorphic form of (−)-modafinil that produces a powder X-ray diffraction spectrum comprising intensity peaks corresponding to interplanar spacings of about 12.38, 8.58, 7.34, 5.00 and 4.09 Å, and a process for the preparation thereof.11-12-2009
20100022653Process for the Preparation of and Crystalline Forms of Optical Enantiomers of Modafinil - The invention relates to a polymorphic form of (−)-modafinil that produces a powder X-ray diffraction spectrum comprising intensity peaks corresponding to interplanar spacings of about 8.54, 4.56, and 3.78 Å, and a process for the preparation thereof.01-28-2010