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Coombes
Allan Gerald Arthur Coombes, Surrey GB
| Patent application number | Description | Published |
|---|---|---|
| 20100062041 | SKIN SUNSTITUTES, PREPARATION METHODS AND USES THEREOF - Provided herein are skin substitutes suitable for use in a living subject for purpose of repairing damaged tissues, methods of producing the skin substitutes and their uses. A biocomposite membrane comprising poly(ε-caprolactone) (PCL) and at least one material selected from collagen and gelatin is provided. In one embodiment, the biocomposite is a 2-component membrane of PCL and gelatin. In another embodiment, the biocomposite is a 3-component membrane of PCL, collagen and gelatin. The bio-composite membrane may be used directly in vivo as a wound dressing, or as a support for cell growth on each side of the membrane to produce an in vitro cultivated artificial skin for future in vivo and/or in vitro applications. | 03-11-2010 |
Anthony C. Coombes, Toronto CA
| Patent application number | Description | Published |
|---|---|---|
| 20110074783 | System, Apparatus and Method for Mapping - The present invention provides a novel apparatus and method for mapping of urban regions. An apparatus includes the remote sensing equipment that is connected to a computer processor. The remote sensing equipment gathers imaging data about an urban region. The computer processor interprets the imaging data to generate a map of the urban region comprising representations that identify a first set of indicia representing physiographic characteristics, a second set of indicia representing different types of built forms, and a third set of indicia representing patterns of human activity associated with both the physiographic characteristics and the built forms. The map can also include a fourth set of indicia representing an intensity level that at least one of the other types of indicia occurs. | 03-31-2011 |
| 20110267355 | System, Apparatus and Method for Mapping - The present invention provides a novel apparatus and method for mapping of urban regions. An apparatus includes the remote sensing equipment that is connected to a computer processor. The remote sensing equipment gathers imaging data about an urban region. The computer processor interprets the imaging data to generate a map of the urban region comprising representations that identify a first set of indicia representing physiographic characteristics, a second set of indicia representing different types of built forms, and a third set of indicia representing patterns of human activity associated with both the physiographic characteristics and the built forms. The map can also include a fourth set of indicia representing an intensity level that at least one of the other types of indicia occurs. | 11-03-2011 |
Brian Coombes, Dundas CA
| Patent application number | Description | Published |
|---|---|---|
| 20110159593 | METHOD OF REDUCING MOTILITY IN BACTERIA BY OVEREXPRESSION OF A GENE OF OI-1 GENOMIC ISLAND - Z0021 was identified as a gene within the O-Island 1 (OI-1) genomic island of verocyto-toxin-producing | 06-30-2011 |
Christine Evelyn Coombes, Eymet FR
| Patent application number | Description | Published |
|---|---|---|
| 20120067749 | Container - A container ( | 03-22-2012 |
Daniel J. Coombes, Glen Ellyn, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20080219213 | DYNAMIC SHARING OF WIRELESS RESOURCES AMONG DIFFERENT COMMUNICATION NETWORKS - Various embodiments are described to enable multiple, independent communication networks to share in an autonomous and dynamic manner unlicensed wireless resources. Generally, this involves determining that a first network node ( | 09-11-2008 |
Heather Madeleine Coombes, Pretoria ZA
| Patent application number | Description | Published |
|---|---|---|
| 20120100503 | DENTAL IMPLANT ASSEMBLY AND COMPONENT - The invention concerns a dental implant assembly including an implant component ( | 04-26-2012 |
John W. Coombes, Wlsa, MT US
| Patent application number | Description | Published |
|---|---|---|
| 20100237307 | Modular solar fence system - Exemplary embodiments include a solar and non-solar fence slat designs for use in a modular fence system. The fence slat comprises an elongated slat body having a front side wall, a back side wall, bottom side wall, top side wall, right side wall and left side wall. The slat first and second fasteners coupled to right and left sides of the elongated slat body and being configured to couple or interlock with adjacent slats. The slat also includes at least one chain-link interface coupler coupled to the back side wall to connect to at least one horizontal cross-bar of a chain-link fence. In an embodiment, the fence slat has a solar panel integrated therewith. | 09-23-2010 |
Kevin R. Coombes, Houston, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20100304993 | BIOMARKERS FOR THE DETECTION OF EARLY STAGE OVARIAN CANCER - The present invention provides methods and compositions for detecting early stage ovarian cancer in a patient. Also, methods for evaluating the ovarian cancer state of a patient are described herein. These methods involve the detection, analysis, and classification of biomarkers in biological samples. | 12-02-2010 |
Raoul C. Coombes, London GB
| Patent application number | Description | Published |
|---|---|---|
| 20090074665 | Diagnosis and treatment of cancer:I - A method of diagnosing cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of SCN5A (and optionally also SCN9A) voltage-gated Na+ channel nucleic acid or protein associated with cancer. A method of diagnosing breast cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of voltage-gated Na+ channel nucleic acid or protein, preferably SCN5A or SCN9A, associated with cancer. A method of treating cancer comprising the step of administering to the patient an agent which selectively prevents the function of SCN5A (and optionally also SCN9A) voltage-gated Na+ channel. A method of treating breast cancer comprising the step of administering to the patient an agent which selectively prevents the function of a voltage-gated Na+ channel, preferably SCN5A or SCN9A. Genetic constructs and molecules useful in such methods. The methods and compositions are particularly suited to breast cancer. | 03-19-2009 |
| 20100273866 | DIAGNOSIS AND TREATMENT OF CANCER: I - A method of diagnosing cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of SCN5A (and optionally also SCN9A) voltage-gated Na+ channel nucleic acid or protein associated with cancer. A method of diagnosing breast cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of voltage-gated Na+ channel nucleic acid or protein, preferably SCN5A or SCN9A, associated with cancer. A method of treating cancer comprising the step of administering to the patient an agent which selectively prevents the function of SCN5A (and optionally also SCN9A) voltage-gated Na+ channel. A method of treating breast cancer comprising the step of administering to the patient an agent which selectively prevents the function of a voltage-gated Na+ channel, preferably SCN5A or SCN9A. Genetic constructs and molecules useful in such methods. The methods and compositions are particularly suited to breast cancer. | 10-28-2010 |
Raoul Charles Coombes, London GB
| Patent application number | Description | Published |
|---|---|---|
| 20100266503 | Breast Cancer Methods, Medicaments and Agents - A method of combating breast cancer in a mammalian individual, the method comprising administering to the individual an agent which reduces the function of the gamma secretase (GS) complex. | 10-21-2010 |
Rcds Coombes, London GB
| Patent application number | Description | Published |
|---|---|---|
| 20100261683 | Selective Inhibitors for Cyclin-Dependent Kinases - This invention provides a class of compounds which are useful for specifically inhibiting cyclin-dependent kinases. This class of compounds finds use in treating diseases resulting from inappropriate activity of cyclin-dependent kinases, including cancer, viral infections (e.g., HIV) neurodegenerative disorders (e.g. Alzheimer's disease), and cardiovascular disorders (e.g. atherosclerosis). Moreover, certain members of this class are particularly useful for inhibiting cyclin-dependent kinase 7 and are especially useful for the treatment of breast cancer. | 10-14-2010 |
Robert J. Coombes, Longmont, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20080244327 | TRACE DEVICE FOR MONITORING ELECTRONIC DEVICE - A trace device for monitoring and storing trace data of a device under test (DUT) is provided. The trace device is coupled in situ with the DUT when the DUT is in its operating environment (e.g., when the DUT is located within a rack, housing, or enclosure including the DUT). The trace device comprises a trace data buffer for storing trace data received from the DUT during operation. | 10-02-2008 |