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Cools
Jan Cools, Leuven BE
| Patent application number | Description | Published |
|---|---|---|
| 20090075972 | Use of Midostaurin for Treating Gastrointestinal Stromal Tumors - The present invention relates to the use of midostaurin, in free form or in pharmaceutically acceptable salt form in the manufacture of a pharmaceutical composition for the treatment of gastrointestinal stromal tumors, and to a method of treatment of warm-blooded animals, preferably humans, in which a therapeutically effective dose of midostaurin is administered to an animal suffering from said disease or condition. | 03-19-2009 |
| 20090076024 | Episomal Fusion Gene - The present invention relates to an episomal structure expressing a functional oncogene, whereby said oncogene is a fusion gene of two chromosomal gene fragments. More specifically, the invention relates to a NUP214-ABL1 fusion product, important in the development of T-cell acute lymphoblastic leukemia, to methods to detect the fusion and to methods to prevent the oncogenic activity of said fusion product. | 03-19-2009 |
| 20110033911 | Episomal fusion gene - The present invention relates to an episomal structure expressing a functional oncogene, whereby said oncogene is a fusion gene of two chromosomal gene fragments. More specifically, the invention relates to a NUP214-ABL1 fusion product, important in the development of T-cell acute lymphoblastic leukemia, to methods to detect the fusion and to methods to prevent the oncogenic activity of said fusion product. | 02-10-2011 |
Jan Cools, Herent BE
| Patent application number | Description | Published |
|---|---|---|
| 20100130586 | DIAGNOSIS AND TREATMENT OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA - The present invention relates to the field of biotechnological means to diagnose or treat T-cell acute lymphoblastic leukaemia. More particularly, the invention relates to methods to diagnose T-cell acute lymphoblastic leukaemia via determining the presence of a duplication of the MYB gene in cells taken from patients. The invention further relates to inhibitors capable of neutralizing the biological activity of MYB alone, or in combination with inhibitors capable of neutralizing the biological activity of NOTCH1, which can be used to treat T-cell acute lymphoblastic leukaemia. | 05-27-2010 |
Jan Jozef Cools, Balen BE
| Patent application number | Description | Published |
|---|---|---|
| 20080308535 | Atmospheric-Pressure Plasma Jet - A plasma jet apparatus for performing plasma processing of an article includes: an elongated central electrode ( | 12-18-2008 |
Marina Cools, Relie BE
| Patent application number | Description | Published |
|---|---|---|
| 20090298897 | Treatment of Inflammatory Disorders With Triazole Compounds - The present invention relates to the use of triazole compounds for reducing inflammation and treating inflammation-associated disorders. | 12-03-2009 |
Marina Lucie Louise Cools, Retie BE
| Patent application number | Description | Published |
|---|---|---|
| 20090192206 | MERCAPTOIMIDAZOLES AS CCR2 RECEPTOR ANTAGONISTS - The present invention relates to a compound of formula (I) | 07-30-2009 |