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Cool

Barry Cool, White Bear Lake, MN US

Patent application numberDescriptionPublished
20110282436Endoprosthesis - A stent includes a MOF which adjusts pore size upon desorption or adsorption of organic molecules.11-17-2011

David Joseph Cool, Florissant, MO US

Patent application numberDescriptionPublished
20120272955Automatic Tracheostomy Suctioning and Nebulizer Medication Delivery System - Computer automated systems for suctioning tracheostomy patients, monitoring the physiological signs of a patient and administering a prescribed dose of medication to the tracheostomy patient.11-01-2012

Derek Cool, London CA

Patent application numberDescriptionPublished
201102997503D TISSUE MODEL FORMATION FROM NON-PARALLEL 2D IMAGES - Biopsy of the prostate using 2D transrectal ultrasound (TRUS) guidance is the current gold standard for diagnosis of prostate cancer; however, the current procedure is limited by using 2D biopsy tools to target 3D biopsy locations. We have discovered a technique for patient-specific 3D prostate model reconstruction from a sparse collection of non-parallel 2D TRUS biopsy images. Our method can be easily integrated with current TRUS biopsy equipment and could be incorporated into current clinical biopsy procedures for needle guidance without the need for expensive hardware additions. We have demonstrated the model reconstruction technique using simulated biopsy images from 3D TRUS prostate images of 10 biopsy patients. This technique of model reconstruction is not limited to the prostate, but can be applied to the reconstruction of any tissue acquired with non-parallel 2-dimensional ultrasound images.12-08-2011

John Cool, Parkville, MO US

Kelli M. Cool, Lawrence, KS US

Patent application numberDescriptionPublished
20080286245PREPARATION OF REGULATORY T CELLS USING ICAM-1 CO-STIMULATION - A method for generating a purified regulatory T cell composition having a CD411-20-2008

Kenneth J. Cool, Castle Rock, CO US

Patent application numberDescriptionPublished
20090245490INTEGRATED TELEPHONY AND VIDEO SYSTEM - An integrated telephony and video system allows a viewer of a program to selectively accept a telephone call based on caller identification information and automatically buffer the program upon acceptance of the call. When the call is terminated, the buffered program is played from the point of interruption until the buffered program is the same as the real-time program. The system may store data about the call, such as the caller identification information and length of the call. Such data may be used to determine a compression format for the buffered program. Such data may also be used to generate a list of callers for whom the user desires to be interrupted while viewing the program.10-01-2009
20100211326ELECTRONIC HYBRIDIZATION ASSAY AND SEQUENCE ANALYSIS - An electronic hybridization assay implements a hybridization reaction, or a sequence analysis, on sequences representative of the sequences of the molecules under examination to provide an output representative of a chemical hybridization reaction. An electronic hybridization machine implements a correlation algorithm where the correlation output provides information regarding the relationship between the molecules under examination. In one aspect, the degree of similarity between the molecules is indicated by the correlation output value. In another aspect, a locus of similarity between the molecules is indicated by a maximum value in the correlation output sequence. In a particular aspect, the sequences are encoded in an optimized format to optimize the operation of the operation of the electronic hybridization machine.08-19-2010

Patent applications by Kenneth J. Cool, Castle Rock, CO US

Kenneth Nicholas Cool, Florissant, MO US

Patent application numberDescriptionPublished
20120272955Automatic Tracheostomy Suctioning and Nebulizer Medication Delivery System - Computer automated systems for suctioning tracheostomy patients, monitoring the physiological signs of a patient and administering a prescribed dose of medication to the tracheostomy patient.11-01-2012

Lonnie F. Cool, North Olmsted, OH US

Patent application numberDescriptionPublished
20120247885Adaptive Torque Plates - An arrangement for securing a carrier for a brake to an axle housing of a vehicle includes a torque plate having an attachment portion securable to the carrier and an annular mounting section securable to a backing plate on the axle housing. The annular mounting section is provided with pluralities of alignment holes and mounting slots, permitting adjustment of a torque plate clocking angle. By way of a torque plate configured in accordance with this invention, clocking angle adjustments can be made in increments of under three degrees.10-04-2012

Lyle Cool, Beaverton, OR US

Patent application numberDescriptionPublished
20100131746Method and apparatus to support separate operating systems in partitions of a processing system - A processing system with multiple processing units may support separate operating systems (OSs) in separate partitions. During an initialization process, a preboot manager in the processing system may copy software to a sequestered area of memory in the processing system. The preboot manager may also configure the processing system to hide the sequestered area of memory from a first partition of the processing system. Also, the preboot manager may use a first processing unit in the processing system to boot an OS on the first partition, and the preboot manager may transmit a boot trigger from the first processing unit to a second processing unit in the processing system. The boot trigger may cause the second processing unit to use the software in the sequestered area of memory to boot a second partition of the processing system. Other embodiments are described and claimed.05-27-2010

Patent applications by Lyle Cool, Beaverton, OR US

Marc W. Cool, Rancho Domingues, CA US

Patent application numberDescriptionPublished
20110247269PLANT STARTER KIT AND METHOD - Kits are disclosed for starting plant seedlings from seeds. The kits can employ self-watering structures and can create microenvironments that foster seed germination and seedling growth. The kits can include structures that minimize the transplanting stress to transplanted seedlings. Methods for growing seedlings from seeds also are disclosed.10-13-2011

Pegie Cool, Keerbergen BE

Patent application numberDescriptionPublished
20120012528SURFACE MODIFIED INORGANIC MATRIX AND METHOD FOR PREPARATION THEREOF - The present invention relates to a method for the modification of metal hydroxide and/or metal oxide surfaces of an inorganic matrix with an organometallic reagent for obtaining an organic functionalized matrix suitable for filtration processes. The method involves the direct covalent binding of organic functional groups by allowing a pre-treated matrix to react with organometallic reagents in the present of a suitable solvent. The present invention further relates to an organic functionalized matrix obtainable or obtained by carrying out a method according to the invention. The invention also provides various uses of a surface-modified matrices as described herein in various industrial applications, including for instance in filtration and/or adsorption and/or separation processes, or as support, e.g. for catalyst systems or for enzyme systems.01-19-2012

Peter Jan Cool, Lochem NL

Patent application numberDescriptionPublished
20110108253Heat Exchanger - A heat exchanger (05-12-2011

Robbert Hans Cool, Groningen NL

Patent application numberDescriptionPublished
20110200552CYTOKINE DESIGN - The present invention relates to novel cytokines, which have a modified selectivity/specificity for their cognate receptors. In particular, the invention relates to a variant TRAIL protein, which has superior selectivity for the death receptor 4 (TRAIL-RI) over the death receptor 5 (TRAIL-R2). In addition, the invention relates to a variant TRAIL protein which exhibits superior selectivity for the death receptor 4 (TRAIL-R1) over the decoy receptors DcR1 (TRAIL-R3) and DcR2 (TRAIL-R4).08-18-2011

Robert A. Cool, Alpharetta, GA US

Patent application numberDescriptionPublished
20090162258LIQUID TREATMENT SYSTEM - A liquid treatment system has a housing defining an interior space. The housing has an inlet port for receiving liquid into the interior space of the housing and an outlet port for allowing liquid to exit the interior space of the housing. The outlet port is spaced from the inlet port so that liquid flows through the interior space of the housing from the inlet port to the outlet port. An ultrasonic waveguide assembly is disposed within the interior space of the housing and includes an ultrasonic horn disposed at least in part intermediate the inlet port and the outlet port of the housing. The ultrasonic horn is operable at an ultrasonic frequency to ultrasonically energize liquid flowing within the housing. An ultraviolet light source emits ultraviolet light into the interior space of the housing to treat liquid flowing therein.06-25-2009

Robert Alan Cool, Alpharetta, GA US

Patent application numberDescriptionPublished
20100067321ULTRASONIC TREATMENT SYSTEM AND METHOD OF USING THE SYSTEM - In an ultrasonic treatment system for ultrasonically treating a substance, an elongate ultrasonic horn is positionable within the substance and excitable to vibrate ultrasonically to energize the substance. The horn has a longitudinal axis and an outer surface for contact with the substance. An agitating member of the system is disposed on the ultrasonic horn and is rotatable about the longitudinal axis of the horn during ultrasonic vibration of the horn to agitate the substance.03-18-2010

Simon Cool, Immunos SG

Patent application numberDescriptionPublished
20120301442TREATMENT OF BONE FRACTURE - The use of mesenchymal stem cells cultured in the presence of HS-2 for the treatment of bone fracture. Repair of bone fracture using such cells is enhanced compared with the treatment of bone fracture using mesenchymal cells cultured without HS-2. These mesenchymal stem cells may be formulated in a pharmaceutical composition and injected directly into tissues surrounding the fracture or used in a biocompatible implant or prosthesis.11-29-2012

Simon Cool, Proteos SG

Patent application numberDescriptionPublished
20080274156Composition forstimulating bone growth and differentiation and method for isolating same - This invention relates to isolated heparan sulphate and use thereof to stimulate bone cell growth and differentiation. The invention also relates to use of heparan sulphate with implants, prosthesis and bioscaffolds to repair and regenerate bone. Such use may be for repair of damaged tissue including bone tissue, for example damage resulting from injury or defect.11-06-2008
20090137038METHODS OF PROLIFERATING STEM CELLS - The invention relates to methods of proliferating stem cells. More particularly, the invention relates to the use of glycosaminoglycans or proteoglycans to promote the growth of stem cells in ex vivo culture, while preserving their multipotentiality.05-28-2009
20090148422METHODS OF PROLIFERATING STEM CELLS - The invention relates to methods of proliferating stem cells. More particularly, the invention relates to the use of glycosaminoglycans or proteoglycans to promote the growth of stem cells in ex vivo culture, while preserving their multipotentiality.06-11-2009

Patent applications by Simon Cool, Proteos SG

Simon Cool, Singapore SG

Patent application numberDescriptionPublished
20120087899Heparan Sulphate - Heparan sulphate from bone marrow stroma is disclosed together with the use of heparan sulphate from bone marrow stroma in the differentiation and/or lineage commitment of stem cells.04-12-2012
20120230964THE ISOLATION AND CHARACTERISATION OF HEPARAN SULPHATES AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT AND STEM CELL CULTURE MEDIA SUITABLE FOR CONDITIONS ASSOCIATED WITH BONE REPAIR - Heparan sulphates isolated from male and female murine liver, their characterisation and use in pharmaceutical compositions, methods of treatment and in stem cell culture media suitable for conditions associated with bone repair.09-13-2012
20120238523GLYCOSAMINOGLYCAN MIXTURES - The present invention relates to osteoblast derived glycosaminoglycan mixtures and to their use in one or more of: inhibition of osteoclastogenesis, enhancement of proliferation of osteoblasts, and/or the treatment or prevention of bone fracture or bone deterioration.09-20-2012

Simon Mckenzie Cool, Singapore SG

Patent application numberDescriptionPublished
20090148420STEM CELLS - Stem cells obtained through in vitro culture with heparan sulphate are described.06-11-2009
20110159071Isolation and Identification of Glycosaminoglycans - The isolation and identification of glycosaminoglycans capable of binding to proteins having a heparin-binding domain is disclosed, as well as the use of the glycosaminoglycans isolated in the growth and/or development of tissue.06-30-2011
20110165132Heparan Sulphate Which Binds BMP2 - The invention relates to heparan sulphate GAGs obtained by affinity chromatography using the heparin-binding domain of BMP2. The GAGs were obtained from osteoblast extracellular matrix and from a commercially available heparan sulfate (Celsus HS).07-07-2011
20110165218Therapeutic Bone Growth and Regeneration - The use of Herapan Sulphate 2 (HS-2) in therapeutic bone growth and regeneration is described. Herapan Sulphate 2 was identified as a variant of Heparan Sulphate purified from embryonic day (E10) of murine neuroepithelia.07-07-2011