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Contreras
Jean-Marie Contreras, Benfeld FR
| Patent application number | Description | Published |
|---|---|---|
| 20100168163 | CYCLIC-ALKYLAMINE DERIVATIVES AS INHIBITORS OF THE INTERACTION BETWEEN MDM2 AND P53 - The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds of formula (I) wherein n, m, p, t, R | 07-01-2010 |
| 20110053937 | Inhibitors of the Interaction Between MDM2 and P53 - The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds of formula (I) | 03-03-2011 |
Jean-Marie Contreras, Benfield FR
| Patent application number | Description | Published |
|---|---|---|
| 20120071508 | CYCLIC-ALKYLAMINE DERIVATIVES AS INHIBITORS OF THE INTERACTION BETWEEN MDM2 AND P53 - The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds of formula (I) | 03-22-2012 |
Juan Contreras, Celra ES
| Patent application number | Description | Published |
|---|---|---|
| 20090023922 | PROCESS FOR PREPARING VORICONAZOLE, NEW POLYMORPHIC FORM OF INTERMEDIATE THEREOF, AND USES THEREOF - The present invention relates to an improved process for preparation of Voriconazole and Voriconazole (1R)-(−)-10-camphorsulfonate. | 01-22-2009 |
Leonel Ruiz Contreras, Bogota CO
| Patent application number | Description | Published |
|---|---|---|
| 20100119380 | SUBSEA PUMPING SYSTEM - A technique is provided for pumping fluid in subsea applications. A self-contained pumping module is created by mounting a pumping unit on a skid that can be lowered to a sea floor. The skid comprises a support structure designed to hold the pumping unit in a desired orientation, such as an inclined orientation with respect to a base of the skid. The self-contained nature of the pumping module facilitates deployment to a sea floor/retrieval from the sea floor to enable use of the pumping module in a variety of subsea applications with reduced complexity and cost. | 05-13-2010 |
Lionel Fernel Gamarra Contreras, Sao Paulo BR
| Patent application number | Description | Published |
|---|---|---|
| 20120070858 | METHOD FOR ISOLATING EXOSOMES FROM BIOLOGICAL SOLUTIONS USING IRON OXIDE NANOPARTICLES - A method for isolating exosomes from blood platelets using superparamagnetic nanoparticles of iron oxide (Fe | 03-22-2012 |
Pablo Contreras, Edmonton CA
| Patent application number | Description | Published |
|---|---|---|
| 20110135797 | FLOCCULATION METHOD - A method is taught for producing freely draining flocculated sediment from a suspension comprising finely divided solids in water. The method comprises dispersing, at increasing concentrations, a charged particle hybrid polymer (CPHP) flocculant into the suspension to determine a minimum concentration of CPHP flocculant above which a freely draining flocculated sediment is produced that has a minimum permeability of 1 Darcy. Then, the concentration of dispersed CPHP flocculant in the suspension is maintained at or above the minimum concentration. | 06-09-2011 |
Roberto Contreras, Guadalupe MX
| Patent application number | Description | Published |
|---|---|---|
| 20100080881 | METHOD FOR THE PRODUCTION OF WHOLE NIXTAMALIZED CORN FLOUR, USING A VACUUM CLASSIFIER COOLER - A process and apparatus for the continuous production of whole nixtamalized corn flour, includes a whole clean corn precooking with a lime solution to effect a partial hydrolysis of pericarp and bran with reduced soluble corn loss in Nejayote wastewater. Moisture content is then stabilized, followed by milling and drying preconditioned corn for further endosperm gelatinization in the whole ground kernel, venting and separating the dry-milled fractions. Adiabatic cooling under a partial vacuum of the vented dry-grind fractions and classifying with an upwardly airstream to strip the fine-grind from the coarse grind while the latter is separated downwardly as a moving bed. Venting and separating the classified fine grind fraction; sifting and recovering the cooled and classified fine grind so segregated from the coarse grind, remilling and further screening the coarse grind produces a whole nixtamalized corn flour for tortilla and whole grain corn-based foods. | 04-01-2010 |
Roland Contreras, Gent BE
| Patent application number | Description | Published |
|---|---|---|
| 20090263863 | MODIFICATION OF PROTEIN GLYCOSYLATION IN METHYLOTROPHIC YEAST - The present invention relates to methods and genetically engineered methylotrophic yeast strains for producing glycoproteins with mammalian-like glycosylation. The present invention also relates to vectors useful for generating methylotrophic yeast strains capable of producing glycoproteins with mammalian-like glycosylation. Glycoproteins produced from the genetically engineered methylotrophic yeast strains are also provided. | 10-22-2009 |
Roland Contreras, Merelbeke BE
| Patent application number | Description | Published |
|---|---|---|
| 20090087882 | Protein secretion in eukaryotic cells - The invention relates to the use of a glucosidase II mutation to increase protein secretion in yeast cells. The invention relates further to the use of yeast cells, comprising a mutant glucosidase II gene, possibly in combination with the expression of a recombinant α-1,2-mannosidase gene and/or a recombinant N-acetylglucosaminyl-transferase gene, as a host for protein secretion. | 04-02-2009 |
| 20090098243 | OVEREXPRESSED AND PURIFIED ASPERGILLUS FICUUM OXIDASE AND NUCLEIC ACID ENCODING THE SAME - The present invention relates to a new isolated nucleic acid sequence comprising a gene that encodes a new fungal oxidase enzyme, and nucleic acid fragments thereof. | 04-16-2009 |
| 20100267084 | PROTEIN GLYCOSYLATION MODIFICATION IN METHYLOTROPHIC YEAST - The present invention provides genetically engineered strains of | 10-21-2010 |
| 20110038887 | Novel Vaccine Against Trypanosoma Cruzi Infection - The present invention relates to a vaccine against | 02-17-2011 |
| 20110104750 | Filamentous Fungi Having Reduced UDP-Galactofuranose Content - A filamentous fungal cell having reduced UDP-galactofuranose is provided. The fungal cell may, in certain embodiments, contain a nuclear genome comprising an inactivated UDP-galactopyranose mutase (UDP-galp mutase) gene and a recombinant nucleic acid for expression of a protein. Also provided are methods of producing a protein using the subject fungal cell, as well as methods of producing the subject fungal cell. | 05-05-2011 |
Roland H. Contreras, Merelbeke BE
| Patent application number | Description | Published |
|---|---|---|
| 20100203644 | DIAGNOSTIC TEST FOR THE DETECTION OF EARLY STAGE LIVER CANCER - The invention provides methods and kits to detect early stage hepatocellular carcinoma or a change in the gradation of hepatocellular carcinoma in mammals. The diagnostic marker is based on the profiling and identification of diagnostic carbohydrates present in a body fluid such as blood serum. | 08-12-2010 |
| 20110136240 | DIAGNOSTIC TEST FOR THE DETECTION OF EARLY STAGE LIVER CANCER - The invention provides methods and kits to detect early stage hepatocellular carcinoma or a change in the gradation of hepatocellular carcinoma in mammals. The diagnostic marker is based on the profiling and identification of diagnostic carbohydrates present in a body fluid such as blood serum. | 06-09-2011 |