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Connelly, PA

Bruce A. Connelly, Gibsonia, PA US

Patent application numberDescriptionPublished
20080305265METHODS AND SYSTEMS FOR COATING ARTICLES HAVING A PLASTIC SUBSTRATE - Methods for coating articles that include a plastic substrate are disclosed. Certain methods include the steps of (i) applying a composition that includes an adhesion promoting agent to at least a portion of the substrate by a first application technique, (ii) applying a composition that includes an adhesion promoting agent over at least a portion of the composition applied in step (i) by a second application technique that is different from the first application technique, and (iii) applying a protective and decorative coating system over at least a portion of the compositions applied in steps (i) and (ii). Systems for coating articles that include a plastic substrate are also disclosed.12-11-2008
20090188987MULTI-CHAMBERED COATING CARTRIDGE - A multiple chambered coating cartridge is disclosed. The coating cartridge may have a container with a first chamber and a second chamber, a removable barrier between the first and second chambers, a first component in the first chamber and a second component in the second chamber wherein at least one of the first component and second component has a low viscosity. Also disclosed are a method of filling a coating cartridge and a method of spray painting utilizing a multiple chambered coating cartridge. In addition, an apparatus for spray painting comprising a spray gun and a cartridge with a removable barrier is disclosed.07-30-2009
20090220795COMPOSITES COMPRISING A MULTI-LAYER COATING SYSTEM - Composites having a multi-layer coating system applied to at least a portion thereof are disclosed. Methods for repairing wind blades, such as the leading edge of the wind blade, are also disclosed.09-03-2009

Patent applications by Bruce A. Connelly, Gibsonia, PA US

Jerry Connelly, Pittsburgh, PA US

Patent application numberDescriptionPublished
20120056746MONITORING SYSTEMS, DEVICES AND METHODS - A system for monitoring wellness of a person, includes a local system in the vicinity of the person. The local system includes a plurality of sensor systems. Each of the plurality of sensor systems is associated with at least one monitored system to monitor changes in state of the monitored systems caused by activity or lack of activity of the person. The local system further includes a local data communication device in communicative connection with each of the plurality of sensor system to receive data from each of the plurality of sensor systems. The system further includes a remote system in communication with the local data communication device. The remote system includes a processing system to process data from the plurality of sensor system based upon predetermined rules. The local data communication device is programmed to transmit data to the remote system. The data transmitted to the remote system includes information on state history of the monitored systems. The data on state history may, for example, include at least a time of a change in from a first state to a second and data related to duration of the second state.03-08-2012

J. Michael Connelly, Manheim, PA US

Patent application numberDescriptionPublished
20110232766Apparatus for Harvesting Rainwater - A rainwater collection apparatus is formed with an outer sleeve member that is adapted to connect with upper and lower downspout portions, and with an internal colander that is operable to collect and filter the rainwater flowing through the upper downspout portion. The colander has an upper flanged edge that removes water flowing along the inside surface of the downspout, a filter area including a plurality of apertures for the passage of rainwater into a catch basin, and a support flange that rests on a base ledge formed on the outer sleeve to define the catch basin. A discharge spout drains the collected rainwater from the catch basin to a remote storage container. An internal opening in the colander allows the passage of debris and the overflow of rainwater from the catch basin through apertures in the colander for discharge through the lower downspout portion.09-29-2011

Margery A. Connelly, Lansdale, PA US

Patent application numberDescriptionPublished
20100189654ANIMAL MODEL FOR EVALUATING VASOMOTOR RESPONSE IN VIVO - A method for evaluating the effect of a compound on vasomotor response in vivo comprises the steps of administering said compound to a rabbit and measuring the diameter of the vessel lumen of a central ear artery of said rabbit in comparison with the baseline diameter of the vessel lumen of said central ear artery of said rabbit, said baseline diameter being measured prior to the administration of said compound.07-29-2010
20100196930CELL BASED ASSAYS FOR THE TRIGLYCERIDE SYNTHESIS PATHWAY - A method for identifying a compound which modulates the activity of acyl-coA: diacylglycerol acyltransferase comprises the steps of contacting a stable isotope labeled fatty acid with cells in either presence or absence of the compound, extracting the cells with isopropyl alcohol, and determining the level of a stable isotope labeled triglyceride in the presence or absence of the compound; wherein a change in the level of the stable isotope labeled triglyceride indicates that the compound modulates the DGAT activity.08-05-2010

Mark C. Connelly, Doylestown, PA US

Patent application numberDescriptionPublished
20110300551METHOD OF PREDICTING CLINICAL OUTCOMES FOR MELANOMA PATIENTS USING CIRCULATING MELANOMA CELLS IN BLOOD - The present invention provides an automated method for capturing and detecting circulating melanoma cells (CMC's) in the blood of patients with melanoma. The absolute number of circulating melanoma cells detected in the peripheral blood tumor load is, in part, a factor in prediction of survival, time to progression, and response to therapy.12-08-2011

Mark Carle Connelly, Doylestown, PA US

Patent application numberDescriptionPublished
20090029378High sensitivity multiparameter method for rare event analysis in a biological sample - A sample of blood containing CTCs, or other cells of interest, is stained with fluorescent markers for image analysis and scanned to identify the presence and location within the cartridge of target cells or subcellular elements. A sample containing desired target cells or subcellular elements is then further processed, in part by photobleaching the sample, so that those same targets may be re-analyzed with additional biomarkers conjugated to the same or different fluorochromes using the same imaging criteria that were used for the initial analysis. The present invention has applications with targets such as circulating epithelial, cells, circulating tumor cells, circulating endothelial cells, leukocytes, lymphocyte subsets, cells containing an organelle or receptor of interest, cellular debris, disrupted cells and their debris, or any other formed element that might be captured and imaged. The invention provides a means to further interrogate individual targets of interest, especially when coupled with genetic analysis such as FISH.01-29-2009
20090136946Automated Enumeration and Characterization of Circulating Melanoma Cells in Blood - The CellTracksĀ® System provides a system to enumerate circulating melanoma cells in blood. The system immunomagnetically concentrates epithelial cells, fluorescently labels the cells and identifies and quantifies circulating melanoma cells. The absolute number of circulating melanoma cells detected in the peripheral blood tumor load is, in part, a factor in prediction of survival, time to progression, and response to therapy. Diagnosis and monitoring of melanoma has been limited by the inability to monitor circulating melanoma cells. The present invention provides a method to enumerate circulating melanoma cells in blood samples. Accordingly, this technology provides a means and device for monitoring disease progression in patients with melanoma.05-28-2009
20090191535Method of assessing metastatic carcinomas from circulating endothelial cells and disseminated tumor cells - A method for assessing cancer in test subjects is described based upon enumeration of circulating endothelial cells and/or disseminated tumor cells in a test subject. This method is used to quantify disseminated tumor cells. Correlations with circulating tumor cells provides prognostic information with high accuracy in assessing the risk of recurrence in patients with primary breast cancer.07-30-2009
20100028915CIRCULATING TUMOR CELL ASSAY - Methods for the detection, enumeration and analysis of circulating tumor cells expressing insulin-like growth factor-1 receptors (IGF-1R) are disclosed. These methods are useful for cancer screening and staging, development of treatment regimens, and for monitoring for treatment responses, cancer recurrence or the like. Test kits that facilitate the detection, enumeration and analysis of such circulating tumor cells are also provided.02-04-2010

Patent applications by Mark Carle Connelly, Doylestown, PA US

Michael Connelly, Manheim, PA US

Patent application numberDescriptionPublished
20090139180WATER CHANNELING SYSTEM FOR GUTTERS - Embodiments of the present invention provide systems and methods for channeling water flowing off the roof of a structure. In one embodiment, the water channeling system includes a gutter, a gutter cover and a clip. The clip is configured to be positioned substantially within the channel defined by the gutter and to engage an inner surface of the gutter lip and a concave portion of the front wall of the gutter. The clip defines an upwardly directed groove that is configured to receive the front edge of the gutter cover.06-04-2009

Michael Connelly, Philadelphia, PA US

Patent application numberDescriptionPublished
20110026704Identity Management and Service Access for Local User Group Based on Network-Resident User Profiles - A profile-based system is employed to manage user identities and preferences, devices, content and/or other aspects of service delivery. The user profiles may be maintained in one or more servers or other elements located in an external network access via a customer premises equipment (CPE) gateway of a local network. The profiles can be used to map users to identities, devices, services, and other features that affect the manner in which a particular user communicates with (or through) the external network.02-03-2011
20110044304Wireless Gateway Supporting A Plurality of Networks - In accordance with various aspects of the disclosure, systems and methods are illustrated for an apparatus comprising a modem component, a wireless communications component, at least one processor, and at least one tangible electronic memory storing data and numerous computer-executable modules to enable wireless hotspots with multiple network identifiers. Examples of at least some of the computer-executable modules includes, but is not limited to an input module, network identifier module, session management module, network management module, automatic location management module, authentication module, bandwidth negotiation module, billing interface module, and activity-based location module.02-24-2011
20110044446Prioritized Call Sessions - A local network call handling device is configured to establish multiple concurrent call sessions between local network end devices and an external network. When a prioritized end device attempts to establish a call session, the call handling device may initially determine if a first call session identifier is available. If so, the call session can be established using that first identifier. If the first identifier is in use for a call session of another end device, the call handling device may either use a different call session identifier for the prioritized end device session or may drop a pre-existing call session to free an identifier for use in connection with the prioritized end device.02-24-2011
20110202956DISPOSITION OF VIDEO ALERTS AND INTEGRATION OF A MOBILE DEVICE INTO A LOCAL SERVICE DOMAIN - A handset or other end device in a local service domain receives video service notifications. The video service notifications can provide information to a user of the end device about a video service (e.g., a television program or a movie) available within a local network. The video service notification can include a request for a response to the notification, with the request having a corresponding URI or other type of link to cause a desired action (e.g., to commence recording or playing content associated with a particular video service). A mobile device configurable for direct communication in a wide area wireless network can join a local service domain and receive services through a gateway of that local service domain.08-18-2011
20110222549Home Gateway Expansion - As described herein, a gateway device may include one or more expansion ports to add functionality. The added functionality can be of any desired type, such as adding telephone call routing capabilities, or high-definition radio capabilities. The added functionality can include new wireless communication abilities, such as adding Bluetooth capability, and the combination may allow greater networked communication.09-15-2011
20110274029Wireless Range Extender - As described herein, Multimedia over Coax Alliance (MoCA) is used to connect a range extender to a base Wireless Access Point (WAP). The MoCA based range extender may be outside the wireless range of the base WAP. In an embodiment, the MoCA based range extender may be in a wireless dead zone of the WAP. The MoCA range extender may support at least the same wireless bands as that of the base WAP. The MoCA based range extender may be automatically discovered in the network and may receive the configuration without intervention. Firmware also may be upgraded from the service provider network through the WAP. The MoCA range extender and its clients may communicate with other devices in the local network as well as other devices in the Authorized Service Domain controlled by the service provider.11-10-2011