Connaughton
Alex Connaughton, Graz AT
Patent application number | Description | Published |
---|---|---|
20150015072 | Power Converter Circuit and Method - A power converter circuit includes a converter series circuit that includes a number of converter units. The converter series circuit is configured to output a series circuit output current. A synchronization circuit is configured to generate at least one synchronization signal. At least one of the converter units is configured to generate an output current such that at least one of a frequency or a phase of the output current is dependent on the synchronization signal, and includes a converter stage with an inverting buck boost topology. | 01-15-2015 |
Cathie Connaughton, Conway, AR US
Patent application number | Description | Published |
---|---|---|
20120283421 | METHODS AND REAGENTS FOR DECREASING CLINICAL REACTION TO ALLERGY - It has been determined that allergens, which are characterized by both humoral (IgE) and cellular (T-cell) binding sites, can be modified to be less allergenic by modifying the IgE binding sites. The IgE binding sites can be converted to non-IgE binding sites by altering as little as a single amino acid within the protein, preferably a hydrophobic residue towards the center of the IgE epitope, to eliminate IgE binding. Additionally or alternatively a modified allergen with reduced IgE binding may be prepared by disrupting one or more of the disulfide bonds that are present in the natural allergen. The disulfide bonds may be disrupted chemically, e.g., by reduction and alkylation or by mutating one or more cysteine residues present in the primary amino acid sequence of the natural allergen. In certain embodiments, modified allergens are prepared by both altering one or more linear IgE epitopes and disrupting one or more disulfide bonds of the natural allergen. In certain embodiments, the methods of the present invention allow allergens to be modified while retaining the ability of the protein to activate T-cells, and, in some embodiments by not significantly altering or decreasing IgG binding capacity. The Examples provided herein use peanut allergens to illustrate applications of the invention. | 11-08-2012 |
Jerry T. Connaughton, Houston, TX US
Patent application number | Description | Published |
---|---|---|
20150075869 | CONTINUOUS GRAVITY FEED SYSTEM FOR FEEDING ADDITIVES TO A DRILLING MUD SYSTEM - An apparatus and a method is provided for feeding drilling fluid additives into drilling mud. The apparatus may have an additive containment device with a top and a bottom. The bottom of the additive containment device may be connected to an outlet. The other end of the outlet may be connected to a valve. A flow nozzle may be connected to the valve so that the flow rate of the additive from the flow nozzle into the drilling mud is substantially constant. | 03-19-2015 |
John F. Connaughton, Laytonsville, MD US
Patent application number | Description | Published |
---|---|---|
20110034682 | OLIGONUCLEOTIDE SEQUENCE FORMULA FOR LABELING OLIGNUCLEOTIDE PROBES AND PROTEINS FOR IN-SITU ANALYSIS - The present invention provides oligonucleotide probes and oligonucleotide probe collections and protein labeling for detecting or localizing a plurality nucleic acid target genes or antigens within a cell or tissue sample. Specifically, the invention provides collections of oligonucleotide probes for use in in situ hybridization analyses in which each probe has a label-domain with the sequence formulas of (CTATTTT) | 02-10-2011 |
20120309951 | OLIGONUCLEOTIDE SEQUENCE FORMULA FOR LABELING OLIGONUCLEOTIDE PROBES AND PROTEINS FOR IN-SITU ANALYSIS - The present invention provides oligonucleotide probes and oligonucleotide probe collections for detecting or localizing a plurality nucleic acid target genes within a cell or tissue sample. Specifically, the invention provides collections of oligonucleotide probes for use in in situ hybridization analyses in which each probe has a label-domain with the sequence formulas of (CTATTTT) | 12-06-2012 |
Michael Connaughton, Holly Springs, NC US
Patent application number | Description | Published |
---|---|---|
20160033726 | LOW LOSS FIBER OPTIC HARNESS - The present arrangement provides for a fiber optic arrangement having at least one light transmitting device, at least one light receiving device, and at least one light path between the light transmitting device and the light receiving device. The light path has first and second segments, each having first and second fiber optic element respectively, with the first segment being located proximate to the light transmitting device and where the second segment is located proximate to the light receiving device. A first fiber optic element of the first segment of the light path has a first dimension, and a second fiber optic element of the second segment of the light path has a second dimension larger than the dimension of the first fiber optic element of the first segment. | 02-04-2016 |
Noel Connaughton, County Roscommon IE
Patent application number | Description | Published |
---|---|---|
20130299429 | WASTEWATER TREATMENT PROCESS - A method for processing fines materials generated as a by-product from the screening and washing of sand and gravel includes the steps of drying, pelletising and firing the fines materials to produce a ceramic material in the form of porous pellets which have enhanced properties for the removal of phosphorus and pathogens from wastewater. | 11-14-2013 |
Shane Connaughton, Daventry GB
Patent application number | Description | Published |
---|---|---|
20140033922 | Methods and Assemblies for Separating Liquid from a Gas-Liquid Stream - A two stage gas-liquid separator assembly includes a housing having an inlet for receiving a gas-liquid stream and an outlet for discharging a gas stream. A first plenum chamber includes a pre-separator that causes liquid to separate from the gas-liquid stream and to drain to a lower portion of the first plenum chamber. A second plenum chamber includes a main separator downstream of the pre-separator that further causes liquid to separate from the gas-liquid stream and to drain to a lower portion of the second plenum chamber. A first drain port drains liquid from the lower portion of the first plenum chamber and a second drain port drains liquid from the lower portion of the second plenum chamber. Liquid drains from the first and second plenum chambers regardless of a pressure difference between a pressure in the first plenum chamber and a pressure in the second plenum chamber. | 02-06-2014 |
Spencer James Connaughton, Palo Alto, CA US
Patent application number | Description | Published |
---|---|---|
20160062459 | SYSTEMS AND METHODS FOR BIOMECHANICALLY-BASED EYE SIGNALS FOR INTERACTING WITH REAL AND VIRTUAL OBJECTS - Systems and methods are provided for discerning the intent of a device wearer primarily based on movements of the eyes. The system can be included within unobtrusive headwear that performs eye tracking and controls screen display. The system can also utilize remote eye tracking camera(s), remote displays and/or other ancillary inputs. Screen layout is optimized to facilitate the formation and reliable detection of rapid eye signals. The detection of eye signals is based on tracking physiological movements of the eye that are under voluntary control by the device wearer. The detection of eye signals results in actions that are compatible with wearable computing and a wide range of display devices. | 03-03-2016 |
Stephanie F. Connaughton, Newton, MA US
Patent application number | Description | Published |
---|---|---|
20120076981 | YOGA MAT WITH SUPPORT AND TRACTION - The present disclosure provides a mat including a compressible first layer, openings formed through one or more first portions and columns disposed in/proximate to the openings. One or more second portions, or at least one column, or both may be configured to be depressed to provide support and traction. The present disclosure further provides a towel including an absorption layer and a compressible region of flexible fiber disposed on one or more first portions of a top surface of the absorption layer. The towel may further include one or more columns disposed either on one or more second portions or in/proximate to openings formed through the one or more second portions. The compressible region of flexible fiber may be configured to be depressed in a compressed configuration to provide support and traction. The mat or the towel may be further adapted to form a grip apparatus. | 03-29-2012 |
20140342118 | YOGA MAT WITH SUPPORT AND TRACTION - The present disclosure provides a layered structure including a top layer, a bottom layer, and a grip component disposed between the two layers such that columns from the grip component extend at least partially through openings in the top layer and/or bottom layer. Also provided are mats including the layered structure such that different grip characteristics are provided on the ends of the mat and/or the two sides of the mat by varying one ore more characteristics or components of the layered structure. | 11-20-2014 |
Stephanie F. Connaughton, Chestnut Hill, MA US
Patent application number | Description | Published |
---|---|---|
20160066648 | FOOTWEAR WITH SUPPORT AND TRACTION - A layered engagement structure includes a first layer with a multiple of openings, the first layer at least partially corresponds to a shape of a foot sole and a multiple of columns, each of the multiple of columns correspond with one of the multiple of openings in the first layer to extend at least partially therein. | 03-10-2016 |