Patent application number | Description | Published |
20100015614 | Chip-Based Device for Parallel Sorting, Amplification, Detection, and Identification of Nucleic Acid Subsequences - An apparatus for chip-based sorting, amplification, detection, and identification of a sample having a planar substrate. The planar substrate is divided into cells. The cells are arranged on the planar substrate in rows and columns. Electrodes are located in the cells. A micro-reactor maker produces micro-reactors containing the sample. The micro-reactor maker is positioned to deliver the micro-reactors to the planar substrate. A microprocessor is connected to the electrodes for manipulating the micro-reactors on the planar substrate. A detector is positioned to interrogate the sample contained in the micro-reactors. | 01-21-2010 |
20100055677 | Method for genetic identification of unknown organisms - A method of rapid, genome and proteome based identification of unknown pathogenic or non-pathogenic organisms in a complex sample. The entire sample is analyzed by creating millions of emulsion encapsulated microdroplets, each containing a single pathogenic or non-pathogenic organism sized particle and appropriate reagents for amplification. Following amplification, the amplified product is analyzed. | 03-04-2010 |
20110027781 | System for Autonomous Monitoring of Bioagents - An autonomous monitoring system for monitoring for bioagents. A collector gathers the air, water, soil, or substance being monitored. A sample preparation means for preparing a sample is operatively connected to the collector. A detector for detecting the bioagents in the sample is operatively connected to the sample preparation means. One embodiment of the present invention includes confirmation means for confirming the bioagents in the sample. | 02-03-2011 |
20110053798 | SYSTEM FOR MIXING FLUIDS BY COALESCENCE OF MULTIPLE EMULSIONS - System, including methods, apparatus, compositions, and kits, for the mixing of small volumes of fluid by coalescence of multiple emulsions. | 03-03-2011 |
20110212516 | FLOW-BASED THERMOCYCLING SYSTEM WITH THERMOELECTRIC COOLER - Thermocycling system, including methods and apparatus, for performing a flow-based reaction on a sample in fluid. The system may include a plurality of segments defining at least two temperature regions, and also may include a plurality of heating elements configured to maintain each temperature region at a different desired temperature. At least one of the heating elements may be a thermoelectric cooler operatively disposed to transfer heat to and/or from a temperature region The system further may include a fluid channel extending along a helical path that passes through the temperature regions multiple times such that fluid flowing in the channel is heated and cooled cyclically. | 09-01-2011 |
20130084572 | CALIBRATIONS AND CONTROLS FOR DROPLET-BASED ASSAYS - System, including methods and apparatus, for performing droplet-based assays that are controlled and/or calibrated using signals detected from droplets. | 04-04-2013 |
20130302792 | CALIBRATIONS AND CONTROLS FOR DROPLET-BASED ASSAYS - System, including methods and apparatus, for performing droplet-based assays that are controlled and/or calibrated using signals detected from droplets. | 11-14-2013 |
20140200164 | SYSTEM FOR DETECTION OF SPACED DROPLETS - System, including methods and apparatus, for detection of spaced droplets. | 07-17-2014 |
Patent application number | Description | Published |
20100173394 | Droplet-based assay system - Systems, including apparatus and methods, for performing assays. These systems may involve separating sample components by partitioning them into droplets or other partitions, amplifying or otherwise reacting the components within the droplets, detecting the amplified components, or characteristics thereof, and/or analyzing the resulting data, among others. | 07-08-2010 |
20110092373 | SYSTEM FOR TRANSPORTING EMULSIONS FROM AN ARRAY TO A DETECTOR - System, including apparatus and methods, for performing droplet-based assays. The system may comprise a droplet transporter configured to pick up droplets from each emulsion of an array of reacted emulsions and to drive flow of the droplets through a detection region. The system also may comprise a detector configured to collect data related to one or more analytes from individual droplets of the reacted emulsions as such individual droplets travel through the detection region. The system further may comprise a controller programmed to determine, based on the data collected, an aspect of the one or more analytes in one or more samples included in droplets of the emulsions. | 04-21-2011 |
20110092376 | SYSTEM FOR DROPLET-BASED ASSAYS USING AN ARRAY OF EMULSIONS - System, including method and apparatus, for performing droplet-based assays. In the method, an emulsion may be obtained that includes droplets packed closely together in a three-dimensional packing arrangement. Data related to an analyte may be collected from individual droplets of the reacted emulsion as such droplets travel serially through a detection region. | 04-21-2011 |
20110092392 | SYSTEM FOR FORMING AN ARRAY OF EMULSIONS - System, including apparatus and methods, for forming an array of emulsions. The system may comprise a plate including an array of emulsion production units. Each unit may include at least one first input well, a second input well, and an output well connected to the first and second input wells by channels that form a droplet generator. The system also may comprise a vacuum or pressure source configured to be connected operatively to wells of the plate to form a pressure drop between the input wells and the output well of each unit that is capable of driving a first fluid and a second fluid from respective first and second input wells of such unit and through the droplet generator, for collection as an emulsion in the output well of such unit. | 04-21-2011 |
20120021423 | CONTROLS AND CALIBRATORS FOR TESTS OF NUCLEIC ACID AMPLIFICATION PERFORMED IN DROPLETS - System, including methods and apparatus, for performing droplet-based tests of nucleic acid amplification that are controlled and/or calibrated using signals detected from droplets. | 01-26-2012 |
20120028311 | CARTRIDGE WITH LYSIS CHAMBER AND DROPLET GENERATOR - Systems, including apparatus, methods, compositions, kits, and software, for preparing, reacting, detecting, and/or analyzing samples in droplet-based assay systems, among others. The disclosure emphasizes, but is not limited to, a disposable cartridge with lysis chamber and droplet chamber, particularly for use in droplet-based assays. | 02-02-2012 |