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Colman

Alan Colman, Edinburgh GB

Patent application numberDescriptionPublished
20080250517Methods - The production of genetically modified animals, in which the genetic modifications are engineered in somatic cells cultured in vitro by gene targeting, is described. Genetically modified cells may then used as nuclear donors to produce, inter alia, live animals. The methods described can also be used to validate loci in animal chromosomes which are suitable sites for transgene addition to cells.10-09-2008

Arne Benjamin Colman, Balham GB

Patent application numberDescriptionPublished
20100032443Dispenser for providing warm wipes - A wipes dispenser enabling the dispensing on-demand of one or more warm wet wipes. The dispenser may comprise three containers, at least one dosing device, and dispensing devices.02-11-2010

Arne Benjamin Colman, Newark GB

Patent application numberDescriptionPublished
20090152281Container with a device to prevent clogging of a dispensing device of the container - For a container (06-18-2009

Patent applications by Arne Benjamin Colman, Newark GB

David R. Colman, Westmount CA

Patent application numberDescriptionPublished
20100310451ALTERED N-CADHERIN PROCESSING IN TUMOR CELLS BY FURIN AND PROPROTEIN CONVERTASE 5A (PC5A) - The present invention relates to a method for diagnosis and/or prognosis of cancer and for monitoring the progression of cancer and/or the therapeutic efficacy of an anti-cancer treatment in a subject by determining the molecular form of cadherin at the cell surface of cancer cells in the subject. The invention also relates to a method for preventing, inhibiting or treating cancer or its metastasis in a subject by increasing the adhesive forms of cadherin and/or decreasing the non-adhesive forms of cadherin at the cell surface. The invention also relates to a method step of determining the expression level of furin and proprotein convertase 5A (PC5A).12-09-2010

Derek Colman, Bedfordshire GB

Patent application numberDescriptionPublished
20080212607Data Transfer Circuit - A data transfer circuit is provided for sending digital data at high rates across short but significant distances within an integrated circuit. The data is sent on parallel conductors that are divided into a number of groups. At the receiving end, a multiplexer selects each of the groups in turn and presents them at a set of conductors that are the same in number as one of the groups. At the transmitting end, a data marshalling circuit takes the bitstream to be transmitted and places it on the conductors in a particular redundant fashion so that the bitstream appears to advance across the set of outputs of the multiplexer. That is particularly useful where those outputs are presented to a pre-emphasis filter and line driver. The apparent data rate can be changed by making two or more of the groups of conductors have identical data.09-04-2008

Derek Alan Colman, Hampshire GB

Patent application numberDescriptionPublished
20090053117Quench Tube, Apparatus and Process For Catalytic Gas Phase Reactions - The present invention relates to a quench tube, having a length (L), a diameter (D) and at least one guenchant inlet per tube which inlet passes guenchant into the tube from the side of said tube, and wherein, D is between 0.04 and 0.10 m and L/D is at least 5. The present invention also relates to an apparatus with one or more of said quench tubes wherein said apparatus comprises a catalyst zone which may have a cross sectional area of at least 0, 01 m2. In processes using said tubes and/or said apparatuses a first gaseous reactant stream and a second reactant stream are contacted with a catalyst to produce a product stream which is quenched on exiting the catalyst. A process for producing olefins by autothermal cracking is also claimed.02-26-2009

Patent applications by Derek Alan Colman, Hampshire GB

Peter Colman, East Melbourne AU

Patent application numberDescriptionPublished
20100190782COMPOUNDS AND METHODS OF USE - In one aspect, the present invention provides for a compound of Formula I07-29-2010
20100210622HETEROCYCLIC COMPOUNDS AND METHODS OF USE - In one aspect, the present invention provides for a compound of Formula I08-19-2010

Peter Malcolm Colman, Victoria AU

Patent application numberDescriptionPublished
20100197711BENZOTHIAZOLE COMPOUNDS - The present invention relates to benzothiazole compounds that mimic the activity of BH3 only proteins and are capable of binding to and neutralizing pro survival Bcl 2 proteins. The invention also relates to the use of such compounds in the regulation of cell death or cell survival and the treatment and/or prophylaxis of diseases or conditions associated with the deregulation of cell death or cell survival.08-05-2010

Peter Malcolm Colman, East Melbourne AU

Patent application numberDescriptionPublished
20090048164THERAPEUTIC PRO-APOPTOTIC BH3-LIKE MOLECULES AND METHODS FOR GENERATING AND/OR SELECTING THE SAME - The present invention relates generally to therapeutic molecules which are useful for modulating apoptosis in a target cell or cell population. More particularly, the present invention provides therapeutic agents which inhibit pro-survival molecules and which are capable of inducing or facilitating apoptosis of a target cell or cell population such as cancer cells. The present invention further provides methods for generating or selecting the therapeutic molecules and pharmaceutical compositions comprising the therapeutic molecules.02-19-2009