Colloca
Christopher Colloca, Chandler, AZ US
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20120130425 | Electromechanical Adjusting Instrument - A chiropractic adjusting instrument comprising a housing; thrust nose piece an impact head to contact a body, a preload switch plunger; a dampening spring; a solenoid having a core; a preload spring; a recoil spring; an electronic pulse system operatively connected to a power source to provide alternating current for energizing the solenoid to impart impulse energy from the core to the thrust nose piece which is reproducible and independent of the power source; and a trigger system for triggering the electronic pulse system comprising a switch activated by the preload switch plunger. Preferably, the chiropractic adjusting instrument includes one or more of the following: an intelligent universal AC power converter; optimized force-time waveform; pulse mode operation; a sensing device having a sense output and a suite of electromechanical components designed to promote reproducible dynamic force impulses and safe operation. | 05-24-2012 |
Christopher J. Colloca, Chandler, AZ US
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20140303670 | Method and Device for Spinal Analysis - A method for interpreting patient treatment results and data is described. The Method uses an electric chiropractic adjusting instrument and software program and preferably comprises the following steps of adjusting a spine of a patient using the electric chiropractic adjusting instrument; gathering electric chiropractic instrument adjustment thrust data, patient spine response to thrusts of the electric chiropractic adjustment instrument, and objective clinician findings; recording the electric chiropractic instrument adjustment thrust data, the patient spine response to the thrusts, and the objective clinician findings in a database; providing real time results and findings; and generating reports based on the thrust data, the patient spine response to the thrusts of the electric chiropractic adjustment instrument, and the objective clinician findings. | 10-09-2014 |
Stefano Colloca, Rome IT
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20090035277 | Hepatitis C Virus Nucleic Acid Vaccine - The present invention features nucleic acid constructs that can be used as a HCV nucleic acid vaccine, vaccine component, or in the production of a HCV vaccine. Described constructs include those: (1) encoding for a chimeric HCV polypeptide containing a NS3-4A region based on a first HCV strain and an NS3-NS4A-NS4B-NS5A or an NS3-NS4A-NS4B-NS5A-NS5B region based on a second strain; and (2) a chimpanzee based adenovector encoding an HCV polypeptide. | 02-05-2009 |
20110217332 | Chimpanzee Adenovirus Vaccine Carriers - The present invention provides recombinant replication-defective adenoviral vectors derived from chimpanzee adenoviruses and methods for generating recombinant adenoviruses in human E1-expressing cell lines. The invention also provides compositions and methods suitable for use for the delivery and expression of transgenes encoding immunogens against which a boosted immune response is desired. The invention further provides methods of generating clinical grade vector stocks suitable for use in humans. In a particular embodiment the invention contemplates the use of vectors comprising transgenes which encode tumor associated antigens in vaccines and pharmaceutical compositions for the prevention and treatment of cancer. | 09-08-2011 |
20120027788 | SIMIAN ADENOVIRUS NUCLEIC ACID- AND AMINO ACID-SEQUENCES, VECTORS CONTAINING SAME, AND USES THEREOF - The present invention relates to novel adenovirus strains with an improved sero-prevalence. In one aspect, the present invention relates to isolated polypeptides of adenoviral capsid proteins such as hexon, penton and fiber protein and fragments thereof and polynucleotides encoding the same. Also provided is a vector comprising the isolated polynucleotide according to the invention and adenoviruses comprising the isolated polynucleotides or polypeptides according to the invention and a pharmaceutical composition comprising said vector, adenovirus, polypeptide and/or polynucleotide. The invention also relates to the use of the isolated polynucleotides, the isolated polypeptides, the vector, the adenoviruses and/or the pharmaceutical composition for the therapy or prophylaxis of a disease. | 02-02-2012 |
20130101618 | CHIMPANZEE ADENOVIRAL VECTOR-BASED FILOVIRUS VACCINES - This invention provides vaccines for inducing an immune response and protection against filovirus infection for use as a preventative vaccine in humans. In particular, the invention provides chimpanzee adenoviral vectors expressing filovirus proteins from different strains of Ebolavirus (EBOV) or Marburg virus (MARV). | 04-25-2013 |
Stefano Colloca, Pomezia IT
Patent application number | Description | Published |
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20120328651 | CHIMPANZEE ADENOVIRUS VACCINE CARRIERS - The present invention provides recombinant replication-defective adenoviral vectors derived from chimpanzee adenoviruses and methods for generating recombinant adenoviruses in human E1-expressing cell lines. The invention also provides compositions and methods suitable for use for the delivery and expression of transgenes encoding immunogens against which a boosted immune response is desired. The invention further provides methods of generating clinical grade vector stocks suitable for use in humans. In a particular embodiment the invention contemplates the use of vectors comprising transgenes which encode tumor associated antigens in vaccines and pharmaceutical compositions for the prevention and treatment of cancer. | 12-27-2012 |