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Collinson
Albert Collinson, Marlborough, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120271033 | HIGH AFFINITY ADAPTOR MOLECULES FOR REDIRECTING ANTIBODY SPECIFITY - Disclosed are methods for identifying high affinity adaptor molecules that bind to both a circulating antibody and a target molecule and redirect the specificity of the circulating antibody to the target molecule. Exemplary high affinity adaptor molecules are also provided. | 10-25-2012 |
Albert Collinson, Marlboro, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090232736 | Dual specificity antibodies and methods of making and using - Antibodies having dual specificity for two different but structurally related antigens are provided. The antibodies can be, for example, entirely human antibodies, recombinant antibodies, or monoclonal antibodies. Preferred antibodies have dual specificity for IL-1α and IL-1β and neutralize IL-1α and IL-1β activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Methods of making and methods of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting two different but structurally related antigens (e.g., IL-1α and IL-1β) and for inhibiting the activity of the antigens, e.g., in a human subject suffering from a disorder in which IL-1α and/or IL-1β activity is detrimental. | 09-17-2009 |
Donald L. Collinson, Lafayette, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100309089 | PLANAR ARRAY ANTENNA HAVING RADOME OVER PROTRUDING ANTENNA ELEMENTS - A subarray of a planar array antenna has a ground plane having a rear face and a front face, radiating elements, each of the radiating elements protruding forward of the front face and physically mounted to the ground plane; circuit elements electrically coupled to the radiating elements, and physically mounted to the ground plane and positioned rearward of the rear face of the ground plane; and a dielectric radome supported on the ground plane defining a continuous surface sealed to the ground plane. The continuous surface includes a forward wall positioned forward of each of the radiating elements to form an environmental seal around the radiating elements. The radome has an intermediate wall intermediate at least one pair of adjacent ones of the antenna elements. | 12-09-2010 |
John P. Collinson, Newcastle Upon Tyne GB
| Patent application number | Description | Published |
|---|---|---|
| 20120324420 | PROCESS FOR DEVELOPMENT OF MONITORING TOOLS - A process for creation of an equipment health monitoring (EHM) tool, including defining functional requirements for a proposed EHM tool in a structured hierarchical format. The functional requirements definition is used to generate an outline model for a plurality of functions of the proposed EHM tool according to a model template, wherein the outline model is captured as one or more graphical representations. Each graphical representation includes at least one component representative of a defined EHM functional requirement. Source code for the proposed EHM tool is automatically generated based upon the graphically represented model and then compiled to create a deployable EHM tool from the source code by applying a compilation strategy dependent on an intended mode of operation for said EHM tool. An EHM generation tool and associated data carrier are also recited. | 12-20-2012 |
Marc Gibson Collinson, Lonan GB
| Patent application number | Description | Published |
|---|---|---|
| 20120039586 | ELECTRIC STEAM GENERATION - A steam generator e.g. for a hand-held portable appliance such as a domestic iron or steam cleaner comprises a water inlet, a boiler, a valve for controlling the entry of water into the boiler and means for delivering a surge of water to the boiler when the valve is opened. Also disclosed is an adaptor for supplying electrical power to a mobile electrical appliance. The adaptor is operable in a corded mode when secured to the appliance for supplying electrical power and water while the appliance is being used; or a cordless mode when secured to a base unit such that electrical and water connection can be made by placing the appliance on or against the base unit; and broken by lifting or moving the appliance away from the base unit. | 02-16-2012 |
| 20120060396 | HAND-HELD STEAM APPLIANCES - A steam generating appliance such as an electric iron comprises a base unit and a hand-held mobile unit which can be releasably coupled to the base unit. The base unit comprises a reservoir for water and a pump for pumping water from the reservoir into the mobile unit when the mobile unit is coupled to the base unit. The mobile unit comprises a boiler and an on-board reservoir for water, wherein the on-board reservoir is adapted to store water received from the base unit under pressure and to deliver the water to the boiler under the control of a user-operable valve. | 03-15-2012 |
Michael Collinson, Camarillo, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20120143006 | ENDOSCOPIC SHEATH ASSEMBLY - A sheath assembly for an endoscope includes an elongate tubular body and a plug. The endoscope has a handle portion and a scope portion extending therefrom to a tip. The body includes first and second wall sections and extends along a longitudinal axis between first and second distal openings located at distal and proximal ends thereof, respectively. The first wall section extends radially about the longitudinal axis to define a scope lumen. The scope portion is receivable in the scope lumen with the distal and proximal ends. The second wall section extends radially about a portion of the first wall section and longitudinally between second distal and proximal end openings. The first and second wall sections define an integral suction lumen in fluid communication with a first source of negative pressure. The plug is mated with the distal end opening and includes a lens surface through which energy is transmissible. | 06-07-2012 |
| 20120323175 | CATHETER ASSEMBLY - A catheter assembly comprises a first catheter including a wall with an inner surface at least partially defining a lumen. A second catheter is connected to the wall of the first catheter and is disposed outward of the inner surface of the wall. The second catheter is at least partially covered by a sheath portion of the first catheter. A first portion of the wall of the first catheter is made of a relatively low durometer elastomeric material and is relatively extensible. A second portion of the wall is formed of a relatively high durometer elastomeric material and is relatively inextensible. | 12-20-2012 |
Michael Collinson, Gelta, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110144425 | Apparatus and Method for Manipulating or Retracting Tissue and Anatomical Structure - Integrated systems and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchoring devices for such purposes. | 06-16-2011 |
| 20110152607 | Apparatus and Method for Manipulating or Retracting Tissue and Anatomical Structure - Integrated systems and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchoring devices for such purposes. | 06-23-2011 |
Mike Collinson, Goleta, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110251592 | DEVICES FOR MAINTAINING SURGICALLY CREATED OPENINGS - Devices and methods are directed to improving the gaseous exchange in a lung of an individual having, for instance, chronic obstructive pulmonary disease. More particularly, conduits may be deployed in the lung to maintain collateral openings (or channels) surgically created through airway walls. This tends to facilitate both the exchange of oxygen ultimately into the blood and decompress hyper-inflated lungs. The conduit includes a radially expandable center section having a first end, a second end, and a passageway extending from the first end to the second end. A control segment may be associated with the conduit to limit the degree of radial expansion. The conduit further includes a plurality of deflectable members extending from the ends of the center section. A tissue barrier may coaxially surround the conduit such that tissue ingrowth is prevented. The conduits may also include hold-down members and bioactive coatings that serve to prevent ejection of the conduit as well as prevent narrowing of the passageway due to tissue ingrowth. | 10-13-2011 |
Sarah Jenny Collinson, Hull GB
| Patent application number | Description | Published |
|---|---|---|
| 20110282309 | WOUND DRESSING AND METHOD OF USE - A system, method, and apparatus are disclosed for dressing a wound. The apparatus comprises a liquid and gas permeable transmission layer, an absorbent layer for absorbing wound exudate, the absorbent layer overlying the transmission layer, a gas impermeable cover layer overlying the absorbent layer and comprising a first orifice, wherein the cover layer is moisture vapor permeable. | 11-17-2011 |
| 20120136325 | SYSTEMS AND METHODS FOR CONTROLLING OPERATION OF A REDUCED PRESSURE THERAPY SYSTEM - Negative pressure wound therapy apparatuses and dressings, and systems and methods for operating such apparatuses for use with dressings are disclosed. In some embodiments, controlling the delivery of therapy can be based on monitoring and detecting various operating conditions. An apparatus can have a controller configured to monitor the duty cycle of a source of negative pressure and, based on the monitored duty cycle, determine whether a leak is present. The controller can be configured to provide an indication that a leak is present. For example, the controller can be configured to suspend and/or pause the delivery of therapy, and to restart the delivery of therapy due to a timeout, request from a user, etc. In addition, the controller can be configured to pause and/or restart the delivery of therapy upon a request from the user, such as in response to the user operating a switch. | 05-31-2012 |
| 20120165764 | SYSTEMS AND METHODS FOR CONTROLLING OPERATION OF A REDUCED PRESSURE THERAPY SYSTEM - Negative pressure wound therapy apparatuses and dressings, and systems and methods for operating such apparatuses for use with dressings are disclosed. In some embodiments, controlling the delivery of therapy can be based on monitoring and detecting various operating conditions. An apparatus can have a controller configured to monitor the duty cycle of a source of negative pressure and, based on the monitored duty cycle, determine whether a leak is present. The controller can be configured to provide an indication that a leak is present. For example, the controller can be configured to suspend and/or pause the delivery of therapy, and to restart the delivery of therapy due to a timeout, request from a user, etc. In addition, the controller can be configured to pause and/or restart the delivery of therapy upon a request from the user, such as in response to the user operating a switch. | 06-28-2012 |
Sarah T. Collinson, Woodland, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100287669 | MODULATION OF ACC SYNTHASE IMPROVES PLANT YIELD UNDER LOW NITROGEN CONDITIONS - The invention provides methods for improving plant yield, particularly under nitrogen limiting conditions. According to the invention, applicants have discovered that modulating ACC synthase activity in plants improves yield of plants, even when grown under low nitrogen conditions. The same plants, while demonstrating improved yield over non-modified plants, exhibited no deleterious effects under normal nitrogen conditions. The invention further provides methods using recombinant expression cassettes, host cells and transgenic plants. | 11-11-2010 |