| Patent application number | Description | Published |
| 20090012053 | Use of LXR agonists for the treatment of osteoarthritis - Disclosed herein are methods of preventing and treating osteoarthritis through the use of LXR agonists. | 01-08-2009 |
| 20090209601 | USE OF RXR AGONISTS FOR THE TREATMENT OF OSTEOARTHRITIS - Disclosed herein are methods of preventing and treating osteoarthritis through the use of RXR agonists. | 08-20-2009 |
| 20100062448 | PROTEIN KINASE C ZETA AS A DRUG TARGET FOR ARTHRITIS AND OTHER INFLAMMATORY DISEASES - The present invention is based on the discovery that ζPKC expression is increased in the tissues of arthritis patients as compared to normal individuals. Accordingly, the present invention provides methods of diagnosing, prognosing, and monitoring the course of arthritis in a patient based on increased ζPKC gene expression in arthritic tissue. The present invention further provides compounds that inhibit the expression of ζPKC for use as remedies in the treatment of arthritis, including, but not limited to, inhibitory polynucleotides and polypeptides, small molecules, and peptide inhibitors. In addition, the present invention provides pharmaceutical formulations and routes of administration for such remedies, as well as methods for assessing their efficacy. | 03-11-2010 |
| 20100074935 | RECOMBINANT LUBRICIN MOLECULES AND USES THEREOF - Recombinant lubricin molecules and uses thereof. Novel recombinant lubricin molecules and their uses as lubricants, anti-adhesive agents and/or intra-articular supplements for, e.g., synovial joints, meniscus, tendon, peritoneum, pericardium and pleura, are provided. | 03-25-2010 |
| 20100080848 | Recombinant Lubricin Molecules and Uses Thereof - Recombinant lubricin molecules and uses thereof. Novel recombinant lubricin molecules and their uses as lubricants, anti-adhesive agents and/or intra-articular supplements for, e.g., synovial joints, meniscus, tendon, peritoneum, pericardium and pleura, are provided. | 04-01-2010 |