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Collingwood
David Collingwood, North Woodchester GB
| Patent application number | Description | Published |
|---|---|---|
| 20100156056 | Machine adaptation - The invention relates to the transmission of power and/or data from/to a stationary part of a machine tool | 06-24-2010 |
David Collingwood, Gloucestershire GB
| Patent application number | Description | Published |
|---|---|---|
| 20090140873 | Machine tool probe - A probe has internal circuitry capable of operating in a plurality of different modes, for example a variety of filter modes and turn off modes. A switch on the probe sends an input to a controller which is arranged to set the mode in response to operation of the switch. The switch may be a push button which is operated externally of the probe by means of an actuator in the form of a plunger. The probe has a workpiece-contacting stylus mounted on a seat from which it is deflectable. The stylus and the seat may comprise the switch. An indicator, e.g., an LED, indicates the mode in response to an output from the controller. The controller outputs a plurality of indications of different modes in a sequence and a mode is selected by operating the switch once the desired mode is indicated. | 06-04-2009 |
Stephen P. Collingwood, West Sussex GB
| Patent application number | Description | Published |
|---|---|---|
| 20100166671 | ORGANIC COMPOUNDS - Medicaments comprising (A) an antimuscarinic agent, (B) a beta-2 adrenoreceptor agonist and (C) a corticosteroid for the treatment of inflammatory or obstructive airways diseases. | 07-01-2010 |
Stephen Paul Collingwood, Horsham GB
| Patent application number | Description | Published |
|---|---|---|
| 20100041887 | QUINUCLIDINE DERIVATIVES BINDING TO MUCARINIC M3 RECEPTORS - Compounds of formula I | 02-18-2010 |
| 20100130506 | Organic Compounds - A compound of Formula I | 05-27-2010 |
| 20100168132 | QUINUCLIDINE DERIVATIVES AND THEIR USE AS MUSCARINIC M3 RECEPTOR ANTAGONISTS - Compounds of Formula (I) ; in salt or zwitterionic form wherein R | 07-01-2010 |
| 20110237572 | Treating diseases mediated by blockade of the epithelial sodium channel with pyrazine-2-carboxamide derivatives - A compound of Formula I | 09-29-2011 |
Trevor Collingwood, Novato, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080233641 | Simultaneous modulation of multiple genes - Disclosed herein are compositions and methods that regulate expression of two or more endogenous genes. | 09-25-2008 |
| 20090042250 | Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression - Disclosed herein are methods and compositions for inactivating a FUT8 gene, using fusion proteins comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins. | 02-12-2009 |
| 20090069259 | Treatment of neuropathic pain with zinc finger proteins - A variety of zinc finger proteins (ZFPs) and methods utilizing such proteins are provided for use in treating neuropathic pain. ZFPs that bind to a target site in genes that are aberrantly expressed in subjects having neuropathic pain are described. In addition, ZFPs that bind to a target site in genes expressed at normal levels in subjects experiencing neuropathic pain, modulation of whose expression results in decreased pain perception, are also provided. For example, genes that are over-expressed in the dorsal root ganglia (DRG) of pain patients (e.g., VR1, TRKA and/or Nav1.8) can be repressed, whereas genes that are under-expressed in the same populations can be activated. | 03-12-2009 |
| 20100003756 | Methods and compositions for generation of Bax-and Bak-deficient cell lines - Disclosed herein are methods and compositions for generation of Bak- and/or Bax-deficient cell lines using engineered nucleases. | 01-07-2010 |
| 20100323424 | Targeted modification of chromatin structure - Methods and compositions for targeted modification of chromatin structure, within a region of interest in cellular chromatin, are provided. Such methods and compositions are useful for facilitating processes such as, for example, transcription and recombination, that require access of exogenous molecules to chromosomal DNA sequences. | 12-23-2010 |
| 20110159541 | Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression - Disclosed herein are methods and compositions for inactivating a FUT8 gene, using fusion proteins comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins. | 06-30-2011 |
Trevor Collingwood, San Pablo, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090023153 | Targeted modification of chromatin structure - Methods and compositions for targeted modification of chromatin structure, within a region of interest in cellular chromatin, are provided. Such methods and compositions are useful for facilitating processes such as, for example, transcription and recombination, that require access of exogenous molecules to chromosomal DNA sequences. | 01-22-2009 |
Trevor N. Collingwood, Novato, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110306559 | METHODS AND COMPOSITIONS FOR TREATING NEUROPATHIC PAIN - Compositions and methods for the treatment of neuropathic pain are provided. Compositions of the invention may comprise proteins with a zinc-finger domain fused to a regulatory domain that is capable of either activating or repressing the expression of a target gene involved in neuropathic pain. Alternatively, compositions of the invention may comprise a nucleic acid sequence encoding a protein of the invention, which nucleic acid sequence may optionally be provided as a plasmid or within a virus or other vector for delivery to a target cell or tissue. Methods of treating neuropathic pain involving treatment of subject with the compositions of the invention are also provided. Exemplary target genes for the treatment of neuropathic pain include VR1, NaV | 12-15-2011 |