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Cole, NJ

Andrew Cole, Robbinsville, NJ US

Patent application numberDescriptionPublished
20080249100PTERIDINONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS - The present invention discloses pteridinone derivatives for use as inhibitors of stearoyl-CoA desaturase having the structure of Formula I:10-09-2008
200802551613-HYDROQUINAZOLIN-4-ONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS - The present invention discloses 3-hydroquinazolin-4-one derivatives for use as inhibitors of stearoyl-CoA desaturase. The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cancer, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.10-16-2008
20100113463PTERIDINONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS - The present invention discloses pteridinone derivatives for use as inhibitors of stearoyl-CoA desaturase having the structure of Formula I:05-06-2010

Andrew G. Cole, Robinsville, NJ US

Patent application numberDescriptionPublished
201100711302-AMINOBENZIMIDAZOLES FOR TREATING NEURODEGENERATIVE DISEASES - The invention relates to 2-aminobenzimidazoles useful in treating disorders that are mediated by A03-24-2011

Andrew G. Cole, Robbinsville, NJ US

Patent application numberDescriptionPublished
20080312215Substituted [1,4]-diazepanes as CXCR3 antagonists and their use in the treatment of inflammatory disorders - CXCR3 inhibitors of formula12-18-2008
20090005568Substituted 2-aminothiazoles for treating neurodegenerative diseases - The invention relates to substituted 2-aminothiazole derivatives useful in treating disorders that are mediated by A01-01-2009
20090023723Purinone derivatives for treating neurodegenerative diseases - The invention relates to purinone derivatives useful in treating disorders that are mediated by adenosine receptor function, including neurodegenerative diseases and inflammation. The compounds are of the general formula:01-22-2009
200901052833-HYDROQUINAZOLIN-4-ONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS - The present invention discloses 3-hydroquinazolin-4-one derivatives for use as inhibitors of stearoyl-CoA desaturase. The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cancer, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.04-23-2009
20090312320METHODS OF TREATMENT COMPRISING THE ADMINISTRATION OF HALOARYL SUBSTITUTED AMINOPURINES OR COMPOSITIONS THEREOF - Provided herein are Aminopurine Compounds having the following structure:12-17-2009
201102304808-HETEROARYLPURINE MNK2 INHIBITORS FOR TREATING METABOLIC DISORDERS - Compounds of the formula09-22-2011

Patent applications by Andrew G. Cole, Robbinsville, NJ US

Carole Cole, Budd Lake, NJ US

Patent application numberDescriptionPublished
20110253718TAMPER EVIDENT RESEALABLE CLOSURE - A container for a food product including a tamper-evident closure which forms an opening of a container. The closure comprises a sealing layer, adhesively sealed to the top of the container around the opening. The sealing layer is releasable from the container by pulling back on the sealing layer and resealable against the top layer to seal the opening when the sealing layer is moved back against the top. The tamper-evident feature comprises a portion of the top adjacent the opening and covered by the sealing layer, which extends from a position spaced from, and extends towards and terminates at the opening of the container. A portion of the tamper-evident feature falls into the container after the sealing layer has been pulled back for a first time to thereby indicate that the container has been previously opened.10-20-2011

Carole A. Cole, Budd Lake, NJ US

Patent application numberDescriptionPublished
20080240627PACKAGE INTEGRITY INDICATING CLOSURE - A resealable closure for a container in which package integrity is indicated by a structure which breaks and/or produces an audible sound when the resealable closure is opened for a first time. The package integrity feature, in one form includes at least one strip initially affixed to two portions which comprise the resealable closure so that upon opening the resealable closure for a first time, at least one of the strips breaks, thereby producing the audible sound. The strips may include a weakened portion such as a narrowing. Integrity of the package is indicated by an intact strip viewable upon opening the resealable closure and conversely, a broken or non-intact strip would indicate that the resealable closure has been previously opened. Package integrity may also be shown by a movable second panel or movable die cut tab portions.10-02-2008

Carole Anne Cole, Budd Lake, NJ US

Patent application numberDescriptionPublished
20100303391Package integrity indicator for container closure - A resealable closure for packages is provided which has a package integrity feature. The closure includes a two-ply material having an inner film layer and an outer film layer, forming a top of container. The outer film layer has a sealing panel completely covering a first panel and a second panel of the inner film layer. The sealing panel is permanently attached to the first panel and is releasably affixed a portion of the inner film layer around the perimeter of the first panel to form an opening in the top when the sealing panel with affixed first panel is peeled back from the top. The sealing panel is resealable against the top to seal the opening when the sealing panel is moved back against the top. The package integrity feature comprises the second panel of the inner layer which separates from the sealing panel to indicate that the container has been previously opened.12-02-2010

Curtis Cole, Ringoes, NJ US

Patent application numberDescriptionPublished
20090149822APPARATUS HAVING A FIBROUS SKIN-CONTACTABLE ELEMENT CONTAINING AN AGENT - The invention features an apparatus for delivering mechanical energy to an expanse of skin, wherein the apparatus includes: (a) a skin-contactable element having a skin-contactable surface, wherein the skin-contactable element includes an agent selected from the group consisting of a benefit agent, an apparatus-enhancing agent, and combinations thereof; (b) a motor; and (c) a transfer member for transferring mechanical energy from the motor to the skin-contactable element in order to provide periodic motion to the skin-contactable surface; wherein the agent is configured to release from the skin contactable element to the expanse of skin upon contacting the skin-contactable surface with the expanse of skin.06-11-2009
20090324523COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER - Ultraviolet radiation-absorbing polymers having a first pendant group that comprises an ultraviolet radiation-absorbing moiety and a second pendant group that comprises at least one siloxane linkage and/or an intermediate length carbon chain are disclosed. Personal care compositions including the ultraviolet radiation-absorbing polymer are provided.12-31-2009
20090324524COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER - Ultraviolet radiation-absorbing polymers having a first pendant group that comprises an ultraviolet radiation-absorbing moiety and a second pendant group that comprises at least one siloxane linkage and/or an intermediate length carbon chain are disclosed. Personal care compositions including the ultraviolet radiation-absorbing polymer are provided.12-31-2009
20090326182COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER - Ultraviolet radiation-absorbing polymers having a first pendant group that comprises an ultraviolet radiation-absorbing moiety and a second pendant group that comprises at least one siloxane linkage and/or an intermediate length carbon chain are disclosed. Personal care compositions including the ultraviolet radiation-absorbing polymer are provided.12-31-2009
20110028993MATERIAL FOR MECHANICAL SKIN RESURFACING TECHNIQUES - An article useful for mechanical skin resurfacing techniques is suitable for transferring mechanical energy from a handheld device to skin placed in contact with the article. The article may be characterized by its Durable Abrasiveness, Compressibility, Displacement, and/or surface roughness. The article may be formed of a fibrous structure having a first major surface having associated therewith an adhesive system and a second major surface, generally opposite the first major surface. The second major surface is arranged and configured to reversibly engage a fastener of a motion-generating unit. The invention also relates to a coupling device for coupling a motorized apparatus to a disposable skin-contactable element. The coupling device includes a water-resistant first attachment and a second attachment for releasably affixing said article to a surface of the motion generation unit.02-03-2011
20110087158APPARATUS HAVING A FIBROUS SKIN-CONTACTABLE ELEMENT CONTAINING AN AGENT - The invention features an apparatus for delivering mechanical energy to an expanse of skin, wherein the apparatus includes: (a) a skin-contactable element having a skin-contactable surface, wherein the skin-contactable element includes an agent selected from the group consisting of a benefit agent, an apparatus-enhancing agent, and combinations thereof; (b) a motor; and (c) a transfer member for transferring mechanical energy from the motor to the skin-contactable element in order to provide periodic motion to the skin-contactable surface; wherein the agent is configured to release from the skin contactable element to the expanse of skin upon contacting the skin-contactable surface with the expanse of skin.04-14-2011
20110195036SUNSCREEN COMPOSITIONS COMPRISING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER - Aqueous compositions including a discontinuous oil phase containing an ultraviolet radiation-absorbing polymer stabilized in a continuous aqueous phase, an oil-gelling polymer, and which are substantially free of non-polymeric ultraviolet radiation-absorbers.08-11-2011

Patent applications by Curtis Cole, Ringoes, NJ US

Curtis A. Cole, Ringoes, NJ US

Patent application numberDescriptionPublished
20090220442SUNSCREEN COMPOSITION COMPRISING A DIBENZOYLMETHANE, AN AMINOHYDROXYBENZOPHENONE, A TRIAZINE AND A TRIAZOLE AS UV FILTERS - The present invention relates to a composition comprising: a) a dibenzoylmethane derivative UV-A absorbing agent, b) a hydroxybenzophenone, c) a triazine derivative, and d) a triazole derivative, and the topical use thereof in protecting mammalian skin or hair from UV radiation.09-03-2009
20100224795TOPICAL COMPOSITION DETECTION - Compositions, devices, methods, and kits are provided for determining the presence of topical compositions on surfaces, such as skin.09-09-2010
20100226861TOPICAL COMPOSITION DETECTION - Compositions, devices, methods, and kits are provided for determining the presence of topical compositions on surfaces, such as skin.09-09-2010

Patent applications by Curtis A. Cole, Ringoes, NJ US

David James Cole, Springfield, NJ US

Patent application numberDescriptionPublished
20110257156GAMMA SECRETASE MODULATORS - In its many embodiments, the present invention provides novel heterocyclic compounds as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the central nervous system using such compounds or pharmaceutical compositions.10-20-2011

Emily Cole, Princeton, NJ US

Patent application numberDescriptionPublished
20110114503ELECTROCHEMICAL PRODUCTION OF UREA FROM NOx AND CARBON DIOXIDE - Methods and systems for electrochemical production of urea are disclosed. A method may include, but is not limited to, steps (A) to (B). Step (A) may introduce carbon dioxide and NOx to a solution of an electrolyte and a heterocyclic catalyst in an electrochemical cell. The divided electrochemical cell may include an anode in a first cell compartment and a cathode in a second cell compartment. The cathode may reduce the carbon dioxide and the NOx into a first sub-product and a second sub-product, respectively. Step (B) may combine the first sub-product and the second sub-product to produce urea.05-19-2011

Emily Barton Cole, Princeton, NJ US

Patent application numberDescriptionPublished
20100187123CONVERSION OF CARBON DIOXIDE TO ORGANIC PRODUCTS - The invention relates to various embodiments of an environmentally beneficial method for reducing carbon dioxide. The methods in accordance with the invention include electrochemically or photoelectrochemically reducing the carbon dioxide in a divided electrochemical cell that includes an anode, e.g., an inert metal counterelectrode, in one cell compartment and a metal or p-type semiconductor cathode electrode in another cell compartment that also contains an aqueous solution of an electrolyte and a catalyst of one or more substituted or unsubstituted aromatic amines to produce therein a reduced organic product.07-29-2010
20110114501PURIFICATION OF CARBON DIOXIDE FROM A MIXTURE OF GASES - A method for purification of carbon dioxide from a mixture of gases is disclosed. The method generally includes steps (A) and (B). Step (A) may bubble the gases into a solution of an electrolyte and a catalyst in an electrochemical cell. The electrochemical cell may include an anode in a first cell compartment and a cathode in a second cell compartment. The cathode generally reduces the carbon dioxide into one or more compounds. The anode may oxidize at least one of the compounds into the carbon dioxide. Step (B) may separate the carbon dioxide from the solution.05-19-2011
20110114502REDUCING CARBON DIOXIDE TO PRODUCTS - A method for reducing carbon dioxide to one or more products is disclosed. The method may include steps (A) to (C). Step (A) may bubble the carbon dioxide into a solution of an electrolyte and a catalyst in a divided electrochemical cell. The divided electrochemical cell may include an anode in a first cell compartment and a cathode in a second cell compartment. The cathode generally reduces the carbon dioxide into the products. Step (B) may vary at least one of (i) which of the products is produced and (ii) a faradaic yield of the products by adjusting one or more of (a) a cathode material and (b) a surface morphology of the cathode. Step (C) may separate the products from the solution.05-19-2011
20110114504ELECTROCHEMICAL PRODUCTION OF SYNTHESIS GAS FROM CARBON DIOXIDE - A method for electrochemical production of synthesis gas from carbon dioxide is disclosed. The method generally includes steps (A) to (C). Step (A) may bubble the carbon dioxide into a solution of an electrolyte and a catalyst in a divided electrochemical cell. The divided electrochemical cell may include an anode in a first cell compartment and a cathode in a second cell compartment. The cathode generally reduces the carbon dioxide into a plurality of components. Step (B) may establish a molar ratio of the components in the synthesis gas by adjusting at least one of (i) a cathode material and (ii) a surface morphology of the cathode. Step (C) may separate the synthesis gas from the solution.05-19-2011
20110226632HETEROCYCLE CATALYZED ELECTROCHEMICAL PROCESS - A method for heterocycle catalyzed electrochemical reduction of a carbonyl compound is disclosed. The method generally includes steps (A) to (C). Step (A) may introduce the carbonyl compound into a solution of an electrolyte and a heterocycle catalyst in a divided electrochemical cell. The divided electrochemical cell may include an anode in a first cell compartment and a cathode in a second cell compartment. The cathode generally reduces the carbonyl compound to at least one aldehyde compound. Step (B) may vary which of the aldehyde compounds is produced by adjusting one or more of (i) a cathode material, (ii) the electrolyte, (iii) the heterocycle catalyst, (iv) a pH level and (v) an electrical potential. Step (C) may separate the aldehyde compounds from the solution.09-22-2011

James Cole, Oxford, NJ US

Patent application numberDescriptionPublished
20110256746ELECTRICAL CONNECTOR HAVING ALIGNMENT MECHANISM - An electrical connector assembly may include a connector body having a conductor receiving end and first and second connector ends formed substantially perpendicularly to an axial direction of the conductor receiving end. The connector body includes a first axial bore that communicates with each of a second axial bore and a third axial bore in the first and second connector ends, respectively. The electrical connector assembly may include a conductor spade assembly received in the first axial bore, wherein the conductor spade assembly includes a spade portion extending between the second axial bore and the third axial bore. A removeable contact may be received within the second axial bore to conductively engage the spade portion of the conductor spade assembly.10-20-2011

Vincent Cole, Rockaway, NJ US

Patent application numberDescriptionPublished
20100276615PROPORTIONAL PILOT ACTING VALVE - A valve assembly comprising a pilot valve; a solenoid; and a main valve, the main valve having an actuator in communication with a pressure control; the pilot valve may facilitate opening the main valve in proportion to an energized level of the solenoid. The solenoid may move the first disc to isolate the inlet port from the pressure control and/or move the second disc to communicate the outlet port with the pressure control. The actuator may move the second disc to isolate the outlet port from the pressure control and/or move the first disc to communicate the inlet port with the pressure control. The pilot valve may isolate both the inlet port and the outlet port from the pressure control when the pilot valve experiences forces in equilibrium from the solenoid and the actuator.11-04-2010