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Coen
Donald Coen, Medfield, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100298164 | STRUCTURE-BASED APPROACH TO DESIGN OF INHIBITORS OF PROTEIN-PROCESSIVITY FACTOR INTERACTIONS - A method for the structure-based identification and selection of inhibitors of processivity factor binding to protein is disclosed herein. Characterization of the protein/processivity factor interface is given. Methods for the structure-based inhibition of processivity factor binding to protein are also given. One embodiment includes a class of peptidomimetics that mimic helical portions of proteins. In addition, methods of treatment of various diseases are given, using the inhibitors of the invention. | 11-25-2010 |
Donald M. Coen, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110118332 | VIRAL MICRORNA - The present invention relates, in general, to micro RN As and. in particular, to viral microRNAs expressed by Herpes Simplex Vims 1 (HSV-1) or Herpes Simplex Virus 2 (HSV-2), to agents that inhibit such microRNAs and to methods of treatment based on the use of such agents. | 05-19-2011 |
Gary A. Coen, Bellevue, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20110125484 | Efficient Text Discrimination - The different advantageous embodiments provide a system for text discrimination comprising a word recognizer and control logic. The word recognizer has language data compiled using a number of finite state automata. The control logic is configured to operate the word recognizer to accept or reject a number of characters as a word. | 05-26-2011 |
Günther Coen, Velbert DE
| Patent application number | Description | Published |
|---|---|---|
| 20090214123 | Method for Associating a Digital Image with a Class of a Classification System - Disclosed is a method for assigning the content of a digital image to a class of a classification system. Said method comprises the following steps: —a predetermined number of F numerical shape characteristics ψ | 08-27-2009 |
Günther Coen, Velbert DE
| Patent application number | Description | Published |
|---|---|---|
| 20090214123 | Method for Associating a Digital Image with a Class of a Classification System - Disclosed is a method for assigning the content of a digital image to a class of a classification system. Said method comprises the following steps: —a predetermined number of F numerical shape characteristics ψ | 08-27-2009 |
Kris Luc Rob Coen, Lede BE
| Patent application number | Description | Published |
|---|---|---|
| 20110002357 | SCREENING INSTALLATION - A screening installation is provided that detects a fire in a greenhouse. The screening installation has at least one screening fabric with an upper side and a rear side, and a first set of polymeric or metallic wires arranged proximate to the upper side of the at least one screening fabric so that a displacement of the fabric is restricted by the first set of polymeric or metallic wires. In addition, at least on of the polymeric or metallic wires in the first set of polymeric or metallic wires is replaced by a linear heat detection wire and/or the first set of polymeric or metallic wires is supplemented with at least one linear heat detection wire. | 01-06-2011 |
Laurent Coen, Montreuil FR
| Patent application number | Description | Published |
|---|---|---|
| 20090226468 | Hybrid tetanus toxoid proteins that migrate retrogradely and transynaptically into the CNS - The non-toxic proteolytic C fragment of tetanus toxin (TTC peptide) has the same ability to bind nerve cells and be retrogradely transported through a synapse as the native toxin. A hybrid protein encoded by the lacZ-TTC gene fusion retains the biological functions of both proteins in vivo, i.e. retrograde transynaptic transport of the TTC fragment and -gal enzymatic activity. After intramuscular injection, enzymatic activity could be detected in motoneurons and connected neurons of the brainstem areas. This strategy is useful for the delivery of a biological activity to neurons from the periphery to the central nervous system. Such a hybrid protein can also be used to map synaptic connections between neural cells. | 09-10-2009 |
| 20100239534 | Hybrid proteins that migrate retrogradely and transynaptically into the CNS - The non-toxic proteolytic C fragment of tetanus toxin (TTC peptide) has the same ability to bind nerve cells and be retrogradely transported through a synapse as the native toxin. A hybrid protein encoded by the IacZ-TTC gene fusion retains the biological functions of both proteins in vivo, i.e. retrograde transynaptic transport of the TTC fragment and β-gal enzymatic activity. After intramuscular injection, enzymatic activity could be detected in motoneurons and connected neurons of the brainstem areas. This strategy is useful for the delivery of a biological activity to neurons from the periphery to the central nervous system. Such a hybrid protein can also be used to map synaptic connections between neural cells. | 09-23-2010 |
| 20110002914 | HYBRID TETNUS TOXOID PROTEINS THAT MIGRATE RETROGRADELY AND TRANSYNAPTICALLY INTO THE CNS - The non-toxic proteolytic C fragment of tetanus toxin (TTC peptide) has the same ability to bind nerve cells and be retrogradely transported through a synapse as the native toxin. A hybrid protein encoded by the LacZ-TTC gene fusion retains the biological functions of both proteins in vivo, i.e. retrograde transynaptic transport of the TTC fragment and βgal enzymatic activity. After intramuscular injection, enzymatic activity can be detected in motoneurons and connected neurons of brainstem areas. This strategy is useful for the delivery of a biological activity to neurons from the periphery to the central nervous system. Such a hybrid protein can also be used to map synaptic connections between neural cells. | 01-06-2011 |
Maurice Coen, Orange Park, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20080272255 | Rail End Cover - A universal rail mounting bracket for attachment of a handrail or fence rail to a support structure. A rail end cover may be inserted over the rail end after the rail has been mounted to the support structure with the bracket. A rail end cover is provided to cover any unsightly gaps or uneven cuts which may have occurred during manufacture or installation of the rail. | 11-06-2008 |
| 20090065756 | Cantilevered Rail Support and Covering - A rail structure for use as a handrail or as part of a fence or guardrail construction. The rail has a rigid channel shaped support member and upper and lower rail caps to enclose the support member with a durable decorative appearance. The cantilever provided by flanges on the support member permit upper and lower rail caps to be snap fit to the support member. | 03-12-2009 |
| 20090183354 | Compression Post Mount - A fence post assembly for mounting to a substructure with a single point of attachment. The post assembly has an outer sleeve surrounding a support member and an attachment rod extending through the support member. The post assembly is mounted to the substructure by securing one end of the attachment rod in the substructure and securing the support member between a compression plate and the substructure by tensioning the upper end of the attachment rod. Attachment points for securing additional fence components to the post are provided by inserting an adapter into a receiving channel defined along a longitudinal length of the support member. | 07-23-2009 |
Maurice G. Coen, Orange Park, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20090078923 | Pocket Rail Construction - A rail structure for use as part of a fence construction. The rail has a rigid support member enclosed by a sleeve, the sleeve having a groove or channel extending along its longitudinal length and a hollow chamber for receiving the support member therein. The channel is dimensioned to receive a plurality of slats disposed in spaced relation to one another such that when received in the channels of opposed rails a fence section is formed. Various modifications to the basic rail structure permit construction of a privacy or containment fence section that may include a plurality of vertical segments, including for example lattice work. | 03-26-2009 |
Stephane Coen, Auckland NZ
| Patent application number | Description | Published |
|---|---|---|
| 20100238452 | Dual Fiber Stretchers for Dispersion Compensation - An optical system having at least two waveguides that are deformable to provide adjustments to dispersion and path length. | 09-23-2010 |
Tom Coen, Zemst BE
| Patent application number | Description | Published |
|---|---|---|
| 20090241499 | Apparatus and method for controlling the speed of a combine harvester - Apparatus for controlling the speed of a combine harvester ( | 10-01-2009 |