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Cochran, CA
Andrea Cochran, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110256127 | ANTI-LRP6 ANTIBODIES - The invention provides anti-LRP6 antibodies and methods of using the same. A particular aspect of the invention provides for bispecific anti-LRP6 antibodies that inhibit signaling by multiple Wnt isoforms. | 10-20-2011 |
Andrea G. Cochran, San Francisco, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090011988 | METHOD FOR TREATING CARTILAGE DISORDERS - The present invention relates to a method for the treatment of a cartilage disorder, including cartilage damaged by injury or degenerative cartilagenous disorders. The method involves contacting the cartilage with an IGF-1 analog with altered affinity for IGF-binding proteins (IGFBPs) or an IGFBP displacer peptide that prevents the interaction of an IGF with an IGFBP and does not bind to a human IGF receptor. | 01-08-2009 |
| 20100130411 | METHOD FOR TREATING CARTILAGE DISORDERS - The present invention relates to a method for the treatment of a cartilage disorder, including cartilage damaged by injury or degenerative cartilagenous disorders. The method involves contacting the cartilage with an IGF-1 analog with altered affinity for IGF-binding proteins (IGFBPs) or an IGFBP displacer peptide that prevents the interaction of an IGF with an IGFBP and does not bind to a human IGF receptor. | 05-27-2010 |
Benjamin D. Cochran, Corte Madera, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100031196 | METHOD AND APPARATUS FOR SELECTING AND HIGHLIGHTING OBJECTS IN A CLIENT BROWSER - A computer implemented method, apparatus, article of manufacture and storage medium, provide the ability to select and highlight objects. A rendered image (containing one or more rendered objects) is displayed in a client browser on a client computer. A run length encoded (RLE) selection buffer is received, from a server across a network, into the client browser. The selection buffer provides a mapping of each pixel from the rendered image to rendered objects. User input is accepted that identifies a location of a cursor with respect to the rendered image. A determination is made, on the client computer, regarding which of the rendered objects has been selected based on the user input and the RLE selection buffer. The selected rendered object is then displayed in a visually distinguishable manner. | 02-04-2010 |
Benjamin David Cochran, Corte Madera, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090109217 | Pre-Computing Image Manipulations - The present disclosure includes, among other things, systems, methods and program products for pre-computing image manipulations. | 04-30-2009 |
Brooks B. Cochran, Northridge, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110152654 | ANALYTE SENSORS COMPRISING BLENDED MEMBRANE COMPOSITIONS AND METHODS FOR MAKING AND USING THEM - Embodiments of the invention provide analyte sensors having elements designed to modulate their chemical reactions as well as methods for making and using such sensors. In certain embodiments of the invention, the sensor includes an analyte modulating membrane that comprises a blended mixture of a linear polyurethane/polyurea polymer, and a branched acrylate polymer. | 06-23-2011 |
Diane Cochran, Mission Veijo, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090319879 | Double click inline edit / single click action - A system, method and prepaid payment card configured to enable web-browser behavior for double-click in-line edit and single click action fields. | 12-24-2009 |
Dustin Cochran, Boulder Creek, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110134645 | LED LAMP ASSEMBLY WITH THERMAL MANAGEMENT SYSTEM - A lighting system is described. The lighting system includes a lamp and a first container including a first phase change material thermally connected to the lamp. Heat generated by the lamp during operation is conducted to the first phase change material. The system also includes a second container including a second phase change material thermally connected to the lamp. Heat generated by the lamp during operation is also conducted to the second phase change material, and the second phase change material has a transition point temperature lower than the transition point temperature of the first phase change material of the first container to account for a temperature drop between the second container and the first container. The lighting system also includes a temperature sensor for reducing lamp power if the lamp becomes too hot, and a mounting bracket which may also conduct heat away from the lamp. | 06-09-2011 |
Gene Paul Cochran, Long Beach, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110127411 | System and Method for Using an Optical Isolator in Laser Testing - According to one embodiment, a method includes receiving a first optical signal at a pulse detector. An electronic pulse of the first optical signal is received at an optical module. A second optical signal is generated at the optical module based on the electronic pulse. At least a portion of the first optical signal is received in a reverse direction at an optical isolator and the second optical signal is received in a forward direction at the optical isolator. The optical isolator substantially transmits the second optical signal to a target in the forward direction. The optical isolator substantially attenuates at least a portion of the first optical signal in the reverse direction. | 06-02-2011 |
Jennifer R. Cochran, Stanford, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080249008 | Mutant epidermal growth factor polypeptides, nucleic acids, and uses therefor - The present invention is based, in part, on our discovery that EGF can be engineered to generate mutants that bind to the EGF receptor (EGFR) of a cell and that have a desirable effect on the activity of the cell. For example, the mutants can agonize the receptor (i.e., increase a biological activity of the receptor), or antagonize the receptor (i.e., decrease or inhibit a biological activity of the receptor). In turn, the rate at which the cell proliferates, for example, can be changed. Moreover, some of these mutants bind EGFR with a higher affinity than wild-type EGF exhibits. The affinity may increase by about, for example, 2-, 5-, 10-, 15-, 20-, 25-, 30-, 50-, or 100-fold relative to wild-type EGF. | 10-09-2008 |
| 20090117166 | Sequential coupling of biomolecule layers to polymers - A bio-mimetic or bio-implantable material based on a sequential process of coupling biomolecule layers to a polymer layer is provided. In general, the material could be based on two or more biomolecule layers starting with one of the layers covalently linked to the polymer layer via cross-linkers and the other layers sequentially and covalently linked using cross-linkers to the previously added layer. The polymer layer could be a hydrogel or an interpenetrating polymer network hydrogel. The first layer of biomolecules could be a collagen type, fibronectin, laminin, extracellular matrix protein, or any combinations thereof. The second layer of biomolecules typically is a growth factor, protein or stimulant. The cross-linkers are either water soluble or insoluble bifunctional cross-linkers or azide-active-ester crosslinkers. The material and process as taught in this invention are useful in the field of tissue engineering and wound healing. | 05-07-2009 |
| 20090257952 | Engineered Integrin Binding Peptides - Engineered peptides that bind with high affinity (low equilibrium dissociation constant (Kd)) to the cell surface receptors of fibronectin (α | 10-15-2009 |
| 20090280182 | Devices for the treatment of wounds and methods and kits therefor - Interpenetrating network hydrogels are described that may be incorporated into wound dressings and/or in implants. The properties of the interpenetrating network hydrogel may be tuned to control an amount of moisture in a wound environment. The devices, methods, and kits described herein may be adapted to treat a variety of wound types at a variety of healing stages over a range of time scales. Some hydrogels may be configured to deliver one or more vulnerary agents to a wound. The interpenetrating network hydrogels may also be adapted to control a rate and/or amount of moisture uptake so that the hydrogels may be used as expandable implants to expand tissue. | 11-12-2009 |
| 20100113708 | Surface modification of interpenetrating polymer networks - Surface modification methods for an interpenetrating polymer network (IPN) hydrogel to provide a basis for cell or tissue attachment are provided. The method involves the activation of functional groups on the surface of the IPN hydrogel. The activated functional groups are then reacted with amine-containing molecules or hydroxyl-containing molecules. The methods (i) can be performed in an aqueous environment and do not require the use of any organic solvent, (ii) do not require UV treatment, thereby avoiding denaturation of the IPN hydrogel or proteins, and/or (iii) can be performed as a one pot reaction. | 05-06-2010 |
| 20110136740 | CYSTINE KNOT PEPTIDES BINDING TO ALPHA IIb BETA 3 INTEGRINS AND METHODS OF USE - Disclosed are peptides having a cystine knot structural motif and comprising a sequence engineered for specificity against α | 06-09-2011 |
Joseph R. Cochran, Grass Valley, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100117273 | PROCESS FOR HOT-FORGING SYNTHETIC CERAMIC - The embodiments of the invention are directed to a synthetic ceramic comprising pyroxene-containing crystalline phase, a clast, and a glass phase, wherein at least a portion of the synthetic ceramic is plastically deformable in a certain temperature range. Other embodiments of the invention relate to a method of making a synthetic ceramic, comprising heating a green ceramic material to 900-1400° C., to a temperature sufficient to initiate partial melting of at least a portion of the green ceramic material, transferring the heated green ceramic material to a press, pressing the heated green ceramic material in a die at 1,000 to 10,000 psi, and transferring the heated, pressed green ceramic material to a furnace for cooling to form the synthetic ceramic. | 05-13-2010 |
Michael Cochran, Aliso Viejo, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110043492 | INPUT DEVICE AND DISPLAY SYSTEM HAVING THE SAME - An input device capable of optically communicating with an electronic apparatus is provided. The input device includes a light source, a force sensor, and a controller. The force sensor is configured to sense a force applied to a tip of the input device and generate a first sensing signal corresponding to the sensed force. The controller is electrically connected to the light source and the force sensor, and configured to receive the first sensing signal and control the light source to generate light pulses in response to the first sensing signal according to a predefined protocol. | 02-24-2011 |
Robert A. Cochran, Sacramento, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080270692 | Enabling and disabling cache in storage systems - Embodiments include methods, apparatus, and systems for enabling and disabling cache in storage systems. One embodiment includes a method that changes a time period for delaying host requests received at a cache of a storage device and converts the storage device from a cache enabled state to a cache disabled state while the storage device is online. | 10-30-2008 |
| 20080270719 | Method and system for efficient snapshot operations in mass-storage arrays - Embodiments of the present invention are directed to efficient snapshot operations that produce multiple, useable snapshot logical units when successively directed to a logical unit, and to mass-storage arrays that support such efficient snapshot operations. In one embodiment of the present invention, allocate-on-write techniques are employed for handling WRITE access operations directed to storage-allocation units not yet overwritten following a snapshot operation. The allocate-on-WRITE technique is enhanced by a background process that continuously defragments the logical-storage-allocation-unit address space referenced by the original logical unit. | 10-30-2008 |
| 20090193195 | CACHE THAT STORES DATA ITEMS ASSOCIATED WITH STICKY INDICATORS - Data items are stored in a cache of the storage system, where the data items are for a snapshot volume. Sticky indicators are associated with the data items in the cache, where the sticky indicators delay removal of corresponding data items from the cache. Data items of the cache are sacrificed according to a replacement algorithm that takes into account the sticky indicators associated with the data items. | 07-30-2009 |
Scot Cochran, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100122781 | ACTUATOR FOR OPERATING A SLIDING CURTAIN - This electro-mechanical actuator is used to operate a curtain mounted to slide along an axis. It comprises a motor ( | 05-20-2010 |