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Coats
Andrew Coats, London GB
| Patent application number | Description | Published |
|---|---|---|
| 20090197851 | THERAPY AND USE OF COMPOUNDS IN THERAPY - A method of treating, preventing or ameliorating chronic heart failure or acute heart failure in a patient the method comprising administering to the patient an effective amount of: a compound that is able to bind to an endotoxin (lipopolysaccharide; LPS) molecule, for example LPS binding protein, BPI, lipoproteins, bile acids or an antibody capable of binding LPS, a compound that is able to bind to an endotoxin (lipopolysaccharide; LPS) molecule or bacterium in the gut, for example charcoal, a bile acid or Fuller's earth, an antibacterial agent that is substantially active in the gut, an agent that is able to inhibit the response by a cell to endotoxin (lipopolysaccharide; LPS), an agent that may form a barrier or that otherwise impedes translocation of bacteria or endotoxin (LPS) from the gut into the patient's circulation. A method of treating, preventing or ameliorating endotoxin-mediated immune activation in acute or chronic heart failure in a patient the method comprising administering to the patient an effective amount of: a compound that is able to bind to an endotoxin (lipopolysaccharide; LPS) molecule, for example LPS binding protein, BPI, lipoproteins, bile acids or an antibody capable of binding LPS, a compound that is able to bind to an endotoxin (lipopolysaccharide; LPS) molecule or bacterium in the gut, for example charcoal, a bile acid or Fuller's earth, an antibacterial agent that is substantially active in the gut, an agent that is able to inhibit the response by a cell to endotoxin (lipopolysaccharide; LPS), an agent that may form a barrier or that otherwise impedes translocation of bacteria or endotoxin (LPS) from the gut into the patient's circulation. | 08-06-2009 |
Andrew Coats, Norwich GB
| Patent application number | Description | Published |
|---|---|---|
| 20120095070 | PREVENTION AND TREATMENT OF SARCOPENIA - The present invention provides a means for prevention and treatment of sarcopenia by administration of a substance that both reduces the sensibility of beta-adrenergic receptors and of 5-HT1a receptors. (S)-pindolol, (S)-propanol, tertalol, or bopindolol are preferred for this purpose. | 04-19-2012 |
Andrew Justin Stewart Coats, London GB
| Patent application number | Description | Published |
|---|---|---|
| 20090023639 | Methods of Treatment - A method of treating weight loss due to underlying disease in a patient, the method comprising administering to the patient an effective amount of an agent which reduces sympathetic nervous system activity. A method of treating weight loss due to underlying disease in a patient the method comprising administering to the patient an effective amount of any one or more of the following: a compound which inhibits the effect of aldosterone such as an aldosterone antagonist; a chymase inhibitor; a cathepsin B inhibitor; a β receptor blocker; an imidazoline receptor antagonist; a centrally acting α receptor antagonist; a peripherally acting α receptor antagonist; a ganglion blocking agent; a drug that has an effect on cardiovascular reflexes and thereby reduces SNS activity such as an opiate; scopolamine; an endothelin receptor antagonist; and a xanthine oxidase inhibitor. The methods are particularly useful in treating cardiac cachexia. | 01-22-2009 |
Stephen Coats, Cambridgeshire GB
| Patent application number | Description | Published |
|---|---|---|
| 20110151612 | Method For Manufacturing An Oled Or A blank For Forming An Oled As Well As Such A Blank Or Oled - Method for manufacturing an organic light emitting device or a blank for forming therefrom an organic light emitting device as well as such a OLED or blank, the organic light emitting device having a light emitting area with two opposite first sides and two opposite second sides, the method comprising at least the following steps: providing a substrate; depositing and partly removing a layer of transparent conductive material on the substrate for forming parallel anode lines which extend between the first sides; depositing and partly removing at least one conductive layer for forming contacts which are connected anode lines; wherein a photoresist layer is deposited so that it fully extends over contacts adjacent the at least one second side except for at least one contact position per cathode line, via which an electric contact between a respective cathode line to be formed and a respective contact is established. | 06-23-2011 |
| 20110291084 | Display Device and Backplane - A display device comprises a plurality of electroluminescent display pixels and a plurality of semiconductor elements (“chiplets”), each pixel being electrically connected to the output of one or more of said semiconductor elements through a via hole in an electrically insulating layer for addressing the plurality of display pixels, and a plurality of colour filters and/or downconverters. The colour filters and/or downconverters and the semiconductor elements are provided on the same surface of the device. | 12-01-2011 |
| 20110291572 | Display Drivers - An active matrix display comprises a display area of the matrix comprising drive circuitry including a control circuit comprising chiplets outside the display area. The output of the control circuit is distributed among the plurality of chiplets. This arrangement is advantageous in that the chiplets allow for a much smaller fan-in and fan-out structure, thus allowing a much larger percentage of the substrate to be devoted to display area. | 12-01-2011 |
| 20110291992 | Optical Sensor Array - An optical sensor array comprises a photo-sensitive area formed by an array of chiplets having individual light-sensitive elements, each element configured to produce a signal or signals in response to incident light. The displacement of a chiplet from a predetermined position is derivable from the output signal or signals of the element or elements associated with the chiplet. The arrangement provides a method of measuring the displacement of at least one chiplet in an active display. | 12-01-2011 |