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Coate
Heather Coate, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090163468 | Fused Bicyclic mTor Inhibitors - Compounds represented by Formula (I) | 06-25-2009 |
| 20090197862 | 2-AMINOPYRIDINE KINASE INHIBITORS - 2-Aminopyridine compounds having the structure of Formula I, and pharmaceutically acceptable salts of these compounds. Compounds of Formula I inhibit the activity of tyrosine kinase enzymes in animals, including humans, and are useful in the treatment and/or prevention of various diseases and conditions. In particular, compounds disclosed herein are inhibitors of kinases, in particular, but not limited to, KDR, Tie-2, Flt3, FGFR3, Ab1, Aurora A, c-Src, IGF-1R, ALK, c-MET, RON, PAK1, PAK2, and TAK1, and can be used in the treatment of proliferative diseases, such as, but not limited to, cancer. The present invention is also directed to a pharmaceutical composition comprising a therapeutically effective amount of a compound of Formula I, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. The present invention is further directed to a method of treating a patient having a condition which is mediated by protein kinase activity by administering to the patient a therapeutically effective amount of the above-mentioned pharmaceutical composition. | 08-06-2009 |
| 20090325928 | 6,6-Bicyclic Ring Substituted Heterobicyclic Protein Kinase Inhibitors - Compounds of the formula | 12-31-2009 |
| 20100099679 | FUSED BICYCLIC mTOR INHIBITORS - Compounds represented by Formula (I) | 04-22-2010 |
| 20110190496 | FUSED BICYCLIC mTOR INHIBITORS - Compounds represented by Formula (I) | 08-04-2011 |
| 20110218183 | Fused Bicyclic mTOR Inhibitors - Compounds represented by Formula (I) | 09-08-2011 |
Heather Coate, Farmingdale, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090118499 | 6,6-Bicyclic Ring Substituted Heterobicyclic Protein Kinase Inhibitors - Compounds of the formula | 05-07-2009 |
Heather Renee Coate, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110312974 | HETEROARYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS - Described herein are compounds that are antagonists of PGD | 12-22-2011 |
Jeremy E. Coate, Ithaca, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090099378 | GENERATION OF PLANTS WITH ALTERED OIL CONTENT - The present invention is directed to plants that display an altered oil content phenotype due to altered expression of ICL nucleic acid. The invention is further directed to methods of generating plants with an altered oil content phenotype. | 04-16-2009 |
Richard S. Coate, Fort Collins, CO US
| Patent application number | Description | Published |
|---|---|---|
| 20100065365 | AUTO-SENSING, AUTOMATIC ADJUSTING EXHAUST BAFFLE - An auto-sensing, automatic adjusting exhaust baffle; for reducing noise emissions produced by internal combustion engines, while improving overall engine performance, i.e., torque and horsepower. The design uses a spherical shape to evacuate spent exhaust gas, thus scavenging the surrounding exhaust gases to adjust the backpressure, while reducing the noise exiting the exhaust pipe at lower rpm's. The device uses a sphere with an internal bearing; sliding linearly on a shaft and said sphere and bearing being acted upon by exhaust gasses and a compression spring mounted axially over the diameter of the shaft. The purpose of this device is to reduce noise while improving tuning of the air/fuel intake system, by adjusting backpressure of the exhaust system. The lesser amount of exhaust pressure, the less the sphere moves, as in idle to just off of idle, this results in a quiet operational mode of the invention. As more exhaust pressure is presented, as in higher throttle positions, the more the sphere moves away from the discharge ports, the louder the sound will be from the exit end of the exhaust pipe, this results in the active mode of the invention, obtaining the desired sound and adjusted backpressure throughout the power band. | 03-18-2010 |