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Clynes
Manfred Clynes, Sonoma, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080223199 | Instant Rehearseless Conducting - A method includes receiving digital inputs from a joystick linked to a computer causing affects to music generated from a first music file, and storing the affected generated music in a second music file. The digital inputs can include movements resulting positioning the joystick. | 09-18-2008 |
| 20090025542 | SHAPING AMPLITUDE CONTOURS OF MUSICAL NOTES - Methods and apparatus, including computer program products, for shaping amplitude contours of musical notes. A method for shaping amplitude contours of musical notes in time of particular pitch and duration includes processing musical notes to modify a contour of an amplitude shape curve of each note differently in accordance with its relationship to its succeeding note, the processing including calculating an initial amplitude shape curve, modifying a first portion of the calculated initial amplitude shape curve to be more convex or more concave, and independently modifying a second portion of the calculated initial amplitude shape curve to be more convex or more concave, the resulting modifications improving a timbre quality. | 01-29-2009 |
| 20100276937 | GENERATING ELECTRICITY USING WIND - Among other things, a wind catching surface is supported to face an oncoming wind and not to rotate continuously in one direction under the influence of the oncoming wind, and an energy converter converts motion, caused by the surface catching the oncoming wind, into electricity. | 11-04-2010 |
| 20100276939 | GENERATING ELECTRICITY USING WIND - Among other things, wind energy can be harnessed without using an outmoded rotational windmill model, which is inherently inefficient because much of the wind energy is bypassed; blade stresses are pronounced; and there is a danger to birds, animals, and in smaller models to people. Efficiency directs rotational devices to be quite large, unaesthetic, and a slur on the environment. Here, the quasi-random movements of hundreds of flexible flaps, called wixels, in an array generates electricity through neodymium magnets and wire coils which move relatively to one another in the wind. Each flap generates small amounts of electricity; the random-like contributions of the many flaps are added electronically using standard methods. The sum is fed negatively into the grid, as in solar panel arrays. Multiple arrays can be arranged as wind farms or can be used on rooftops or back yards without danger. Various colored wixels provide for mobile artistic design, an environmental plus, and in large installations for advertising. | 11-04-2010 |
Martin Clynes, Dublin IE
| Patent application number | Description | Published |
|---|---|---|
| 20100190258 | METHOD OF PRODUCING RECOMBINANT BIOLOGICAL PRODUCTS - A method of producing a recombinant biological product, which method employs a mammalian producer cell culture, comprises the steps of generating a biomass of mammalian producer during an initial phase of cell culture, and causing an increase in a level of one or more of the miRNA molecules of Table 1 within the mammalian producer cells once a desired concentration of mammalian producer cells has been achieved. The method may also comprise the step of increasing a level of an inhibitor of one or more of the miRNA molecules of Table 1 within the mammalian producer cells at the start of or during an initial phase of culture. | 07-29-2010 |
Martin Clynes, Clontarf IE
| Patent application number | Description | Published |
|---|---|---|
| 20090017460 | DIFFERENTIAL EXPRESSION PROFILING ANALYSIS OF CELL CULTURE PHENOTYPES AND USES THEREOF - The present invention provides, among other things, systems and methods for identifying genes and proteins that regulate and/or are indicative of cell phenotypes based on expression profiling analysis. The present invention further provides methods of manipulating identified genes and proteins to engineer improved cell lines. | 01-15-2009 |
| 20090186358 | Pathway Analysis of Cell Culture Phenotypes and Uses Thereof - The present invention provides methods for systematically identifying genes, proteins and/or related pathways that regulate or indicative of cell phenotypes. The present invention further provides methods for manipulating the identified genes, proteins and/or pathways to engineer improved cell lines and/or to evaluate or select cell lines with desirable phenotypes. | 07-23-2009 |
Raphael Clynes, West Nyack, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090214533 | METHODS FOR CONVERTING OR INDUCING PROTECTIVE IMMUNITY - The invention is based in part on the finding that suppressing regulatory T cell function is needed in order to convert passive immunity into active antigen-specific immunity. Generally, the methods of the invention comprise at least the combination of: (1) increasing the amount of immune complexes in the subject, wherein the immune complex comprises a target antigen and a immunoglobulin molecule comprising (i) a variable region specific to the target antigen and (ii) a Fc receptor binding region; and (2) inhibiting regulatory T cell function or decreasing/depleting the regulatory T cell population in the subject. | 08-27-2009 |
Walter J. Clynes, O'Fallon, MO US
| Patent application number | Description | Published |
|---|---|---|
| 20080223881 | Trigger Sprayer Having a Two-Piece Shroud with Top and Bottom Pieces - A trigger sprayer that is manually held and operated to pump liquid from an attached bottle and dispense the liquid in a selected discharge pattern from the trigger sprayer has an aesthetically appearing shroud that is comprised of only two pieces that snap together over the exterior of the trigger sprayer housing. | 09-18-2008 |