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Clinch

Cheryl Julia Clinch, Bristol GB

Patent application numberDescriptionPublished
20100015234Pharmaceutical preparations and their manufacture - A method for making a composition comprising active particles comprising an active substance comprises the steps of a) providing an emulsion having a dispersed phase comprising a solution of the active substance in a solvent and b) inducing the formation, in the emulsion, of solid particles comprising the active substance. The particles may be isolated from the emulsion. Active particles having a normalized kurtosis of at least 5 and a mean diameter of less than 100 μm are provided.01-21-2010

Colin Clinch, Basingstoke GB

Patent application numberDescriptionPublished
20080199249METHOD FOR ANCHORING A JOINING ELEMENT IN AN OBJECT AND JOINING ELEMENT TO BE USED IN THE METHOD - A joining element to be anchored in an object (08-21-2008
20100313517METHOD FOR ANCHORING A JOINING ELEMENT IN AN OBJECT AND JOINING ELEMENT TO BE USED IN THE METHOD - A joining element to be anchored in an object with the aid of a thermoplastic material and mechanical vibration comprises a sealing portion and a wall anchoring portion. The sealing portion is substantially cylindrical and has a smooth circumferential surface. The wall anchoring portion has a circumferential surface which comprises the thermoplastic material and energy directors. A cross section of the sealing portion envelops the cross section (including energy directors) of the wall anchoring portion and is arranged adjoining to the latter on its proximal side. The joining element is anchored in an opening provided in the object wherein a cross section of the opening corresponds to the cross section of the sealing portion of the joining element such that the latter can be forced into a mouth of the opening resulting in a press fit. For anchoring the joining element in the opening, mechanical vibrations e.g. ultrasonic vibrations are coupled into the joining element and the latter is forced into the opening until at least a distal part of the sealing portion is positioned within the opening. Thereby, the thermoplastic material of the circumferential surface of the wall anchoring portion is liquefied and pressed into the opening wall, wherein the sealing portion prevents the liquefied material to penetrate through the mouth and therefore the mouth remains clear cut, i.e. does not get blurred by the liquefied material.12-16-2010

David Stewart Clinch, Wiltshire GB

Patent application numberDescriptionPublished
20090250920Security device for security substrates - The invention relates to a security device for security substrates, such as paper, used for making security documents, such as bank notes, having anti-counterfeitable features. The security device comprises a carrier of an at least partially light transmitting polymeric material, said carrier being provided with indicia. The indicia comprise a first component being at least one non-alphanumeric pattern which repeats along the length of the device and is formed from at least one fine line, and a second component being alphanumeric characters, the two components being registered to and interlinked with each other.10-08-2009

Keith Clinch, Lower Hutt NZ

Patent application numberDescriptionPublished
20090325986Deazapurine Analogs of 1'-Aza-L-Nucleosides - The invention relates to compounds of the formula (I), which are L-enantiomeric forms of nucleoside analogues, and to pharmaceutical compositions containing the compounds, methods of treating certain diseases, including cancer, bacterial infection, parasitic infection, and T-cell mediated diseases, using the compounds, processes for preparing the compounds, and intermediates useful in the preparation of the compounds.12-31-2009
20110046167ACYCLIC AMINE INHIBITORS OF 5-METHYTIOADENOSINE PHOSPHORYLASE AND NUCLEOSIDASE - The present invention relates to compounds of the general formula (I) which are inhibitors of 5′-methylthioadenosine phosphorylase or 5′-methylthioadenosine nucleosidase. The invention also relates to the use of these compounds in the treatment of diseases or conditions in which it is desirable to inhibit 5′-methylthioadenosine phosphorylase or 5′-methylthioadenosine nucleosidase including cancer, and to pharmaceutical compositions containing the compounds.02-24-2011
20110130412Acyclic amine inhibitors of nucleoside phosphorylases and hydrolases - The invention relates to compounds of the general formula (I) which are inhibitors of purine nucleoside phosphorylases (PNPs) and/or nucleoside hydrolases (NHs). The invention also relates to the use of these compounds in the treatment of diseases and infections including cancer, bacterial infections, protozoal infections, and T-cell mediated disease and to pharmaceutical compositions containing the compounds.06-02-2011

Keith Clinch, Wellington NZ

Patent application numberDescriptionPublished
20080280334Method for Preparing 3-Hydroxy-4-Hydroxymethyl-Pyrrolidine Compounds - A process is disclosed for preparing (3R,4R)-3-hydroxy-4-hydroxymethylpyrrolidine, the compound of formula (I), or (3S,4S)-3-hydroxy-4-hydroxymethylpyrrolidine, the compound of formula (Ia) involving, as a key step, the enzyme-catalysed enantioselective hydrolysis of a racemic 3,4-trans-disubstituted pyrrolidinone compound of formula (II).11-13-2008

Noah F. Clinch, Kent GB

Patent application numberDescriptionPublished
20080285795METHOD AND APPARATUS FOR ACQUIRING DIGITAL MICROSCOPE IMAGES - A method and apparatus for acquiring digital microscope images is disclosed, in which a plurality of magnified images of a specimen are captured for tiling together to provide an overall composite image of the specimen. In accordance with the described method, the specimen is moved relative to an imaging system comprising a microscope and camera in a predetermined path whilst the plurality of magnified images are captured. In a preferred embodiment, the specimen, contained on a slide, is mounted on a movable microscope stage, and is moved beneath the microscope in the predetermined path. The velocity of the movement of the stage and the shutter speed of the camera is computer controlled to capture overlapping, clear images.11-20-2008