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Claudio

Anne Claudio, San Francisco, CA US

Patent application numberDescriptionPublished
20120004983SYSTEMS AND METHODS FOR DETERMINING THE EFFICACY OF ADVERTISING - A computer-implemented method for determining effectiveness of content includes receiving, by a computing device, a plurality of attributes relating to rendered content, the plurality of attributes including at least one attribute that characterizes a consumer response to the rendered content and at least one attribute that characterizes a creative strength of the rendered content, generating, by a computing device, an index score indicative of an effectiveness of the content using a statistical analysis of the collected attributes, and storing the index score in memory.01-05-2012

Christopher Claudio, Yarmouth, ME US

Patent application numberDescriptionPublished
20100305974MEDICATION REFILL ADVISOR SYSTEM AND METHOD - A system and method for automated medication refill are provided, wherein the system and method reduce the time spent on, and potential for error in, accommodating medication refill requests. In one embodiment, the system includes a computer device for executing a medication information input function, a patient information input function, a refill protocol determination function, a refill analysis function, and an automated refill advisory output function. In a preferred embodiment, the system also executes an automatic pharmacy refill authorization function. The system includes a database incorporated therein or in electronic communication therewith. The system and method of the present invention provide a mechanism for medication refill protocols that provides specific patient care guidance for prescribed medications.12-02-2010

Pier Paolo Claudio, Huntington, WV US

Patent application numberDescriptionPublished
20100062435Methods for Stem Cell Production and Therapy - The present invention relates to methods for rapidly expanding a stem cell population with or without culture supplements in simulated microgravity conditions. The present invention relates to methods for rapidly increasing the life span of stem cell populations without culture supplements in simulated microgravity conditions. The present invention also relates to methods for increasing the sensitivity of cancer stem cells to chemotherapeutic agents by culturing the cancer stem cells under microgravity conditions and in the presence of omega-3 fatty acids. The methods of the present invention can also be used to proliferate cancer cells by culturing them in the presence of omega-3 fatty acids. The present invention also relates to methods for testing the sensitivity of cancer cells and cancer stem cells to chemotherapeutic agents by culturing the cancer cells and cancer stem cells under microgravity conditions. The methods of the present invention can also be used to produce tissue for use in transplantation by culturing stem cells or cancer stem cells under microgravity conditions. The methods of the present invention can also be used to produce cellular factors and growth factors by culturing stem cells or cancer stem cells under microgravity conditions. The methods of the present invention can also be used to produce cellular factors and growth factors to promote differentiation of cancer stem cells under microgravity conditions.03-11-2010

Pier Paolo Claudio, Philadelphia, PA US

Patent application numberDescriptionPublished
20090061414Method for quantification of recombinant viruses - Titration is an important and critical step in dosing recombinant virus for gene therapy. A relatively fast, convenient and sensitive method that allows for precise quantification of recombinant retrovirus is presented. The method is based on PCR amplification of a foreign gene by the PRINS (primer in situ DNA synthesis) technique. The PRINS technique is based on the sequence-specific annealing of unlabeled oligonucleotide DNA it situ. This oligonucleotide operates as a primer for in situ chain elongation catalyzed by the Taq I polymerase. Using -labeled nucleotides as a substrate for chain elongation, the neo-synthetic DNA is labeled by an FITC-conjugated anti-antibody. To avoid the possibility of false positives, the puromycin resistance gene, which is associated with the transgene in the same viral vector and is not normally present in mammalian cells was amplified. The retroviral titer was evaluated by counting FITC-positive cells after PRINS labeling, while knowing the number of cells that were transduced with different amounts of viral supernatant. A comparable viral concentration of 1×1003-05-2009

Selva Claudio, Biella Pavignano IT

Patent application numberDescriptionPublished
20100321435METHOD FOR THE UNIVOCAL MARKING OF MATERIALS, AND INK FOR CARRYING OUT THE SAME - Described herein is a method for unique marking of various materials that can be obtained using an ink formulated with micronized microparticles and/or microencapsulated microdrops of various nature dispersed in a suitable vehicle; said ink, once applied to each individual product, forms an original and distinctive map.12-23-2010