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Clarke, WI

Gerald P. Clarke, Menasha, WI US

Patent application numberDescriptionPublished
20120035724Accommodating intraocular lens and methods of use - An accommodating intraocular lens, for use in an eye, is made from flexible, optionally elastic, bio-compatible lens body material surrounding a s closed and sealed lens cavity which is filled with bio-compatible optical liquid, optionally a gel. The optical liquid has a refractive index sufficiently high to, in cooperation with the ciliary muscle, focus light, incident on the eye, on the retina, and to provide accommodation. The curvature of the front surface of the lens is deformable, by the pressure expressed by the ciliary body during the to accommodative effort, thus to change the radius of curvature of the anterior body member and/or the posterior body member, thus providing smooth focusing, including from far distance in the relaxed state to near distance of less than 50 centimeters in the accommodative state.02-09-2012

Keisha Clarke, Appleton, WI US

Patent application numberDescriptionPublished
20090220616MOISTURIZING AND LUBRICATING COMPOSITIONS - The present invention is generally directed to moisturizing and lubricating compositions for use on the bodyfacing surface of an absorbent product or on one or both faces of a tissue product. The moisturizing and lubricating compositions comprise an emollient, a humectant, and immobilizing agent and a compatibilizing agent. Optionally, the moisturizing and lubricating compositions can comprise a dispersing agent.09-03-2009

Patent applications by Keisha Clarke, Appleton, WI US

William R. Clarke, Colgate, WI US

Patent application numberDescriptionPublished
20100284929FLUORESCENT IMAGING OF TUMORS USING PHOSPHOLIPID ETHER COMPOUNDS - The invention generally relates to the use of novel fluorescent phospholipid ether compounds and compositions comprising these compounds in fluorescence imaging of tumors. A preferred compound of the present invention has the following structural formula:11-11-2010
20100284930FLUORESCENT IMAGING OF SKIN CANCERS USING PHOSPHOLIPID ETHER COMPOUNDS - The invention generally relates to novel fluorescent phospholipid compounds, compositions comprising these compounds, and their use in a variety of diagnostic applications, including fluorescence imaging of tumors. A preferred compound of the present invention has the following structural formula:11-11-2010
20100284931FLUORESCENT PHOSPHOLIPID ETHER COMPOUNDS, COMPOSITIONS, AND METHODS OF USE - The invention generally relates to novel fluorescent phospholipid compounds, compositions comprising these compounds, and their use in a variety of diagnostic applications, including fluorescence imaging of tumors. A preferred compound of the present invention has the following structural formula:11-11-2010
20100286510USE OF FLUORESCENT PHOSPHOLIPID ETHER COMPOUNDS IN BIOPSIES - The invention generally relates to the use of novel fluorescent phospholipid compounds and compositions comprising these compounds in biopsy applications. A preferred compound of the present invention has the following structural formula:11-11-2010
20100316567ETHER AND ALKYL PHOSPHOLIPID COMPOUNDS FOR TREATING CANCER AND IMAGING AND DETECTION OF CANCER STEM CELLS - Methods and compositions utilizing ether and alkyl phospholipid ether analog compounds for treating cancer and imaging, monitoring, and detecting cancer stem cells in humans.12-16-2010
20110064660DEUTERATED ALKYL PHOSPHOLIPID COMPOUNDS, COMPOSITIONS, AND METHODS OF USE - The invention generally relates to novel deuterated phospholipid compounds, compositions comprising these compounds, and their use in a variety of cancer therapy and diagnostic applications.03-17-2011
20110064661NON-RADIOACTIVE PHOSPHOLIPID COMPOUNDS, COMPOSITIONS, AND METHODS OF USE - The present invention provides phospholipid ether and alkyl phospholipid compounds and their combinations with other cancer therapy agents. More specifically, the invention relates to the use of phospholipid ether compounds comprising a “cold” isotope of iodine, e.g. 03-17-2011
20110216957APPARATUS AND METHOD FOR RECONSTRUCTING AN IMAGE WITH REDUCED MOTION ARTIFACTS - A computer readable storage medium having a computer program stored thereon and representing a set of instructions that when executed by a computer causes the computer to calculate a mapping function that provides a location of each sub-volume of an imaging volume as a function of time from ultrasound data and determine a respective acquisition window for each sub-volume of the imaging volume from the mapping function. The instructions also cause the computer to reconstruct an image of the imaging volume substantially free of motion artifacts from imaging data acquired from the imaging volume.09-08-2011
20110218423WEARABLE ULTRASOUND PROBE ASSEMBLY AND METHOD OF MANUFACTURING SAME - A wearable ultrasound probe apparatus includes a wearable membrane. An ultrasound transducer is also included that is integrated into the wearable membrane and configured to maintain a substantially consistent contact with a surface of an object to be imaged when the object has the wearable membrane disposed thereon.09-08-2011
20110218438ULTRASOUND APPARATUS AND METHOD OF MANUFACTURING SAME - An ultrasound apparatus includes an ultrasound probe and a probe positioning device operably connected to the ultrasound probe. The probe positioning device is configured to provide one of an orientation and a position of the ultrasound probe during ultrasound imaging.09-08-2011