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Clarke, AU

Adam W. Clarke, Five Dock Nsw AU

Patent application numberDescriptionPublished
20100297134HUMANISED ANTIBODIES WITH ANTI-TUMOUR ACTIVITY - The present invention provides humanised antibodies and binding domains thereof with anti-tumour activity. In particular the humanised antibodies have specific binding to and direct killing of human colon tumour cells and display potent immune-mediated cytotoxic activity against human colon cancer cells in vitro using antibody-dependent cell-mediated cytotoxicity (ADCC) and complement dependent cytotoxicity (CDC) assays and in vivo using mouse tumour models.11-25-2010

Adam W. Clarke, Russell Lea AU

Patent application numberDescriptionPublished
20080255343CHIMERIC ANTIBODIES - The present invention provides a chimeric antibody or an antigen-binding portion thereof. The antigen-binding portion comprises at least two complementarity determining regions (CDR) and at least three framework regions, wherein at least one CDR is a New World primate CDR10-16-2008

Adam William Clarke, Five Dock AU

Patent application numberDescriptionPublished
20110262445ANTI-IL-12/IL-23 ANTIBODIES - The present invention provides an antibody comprising an antigen binding domain which binds to human IL-12 and human IL-23. The antibody binds human IL-12p40 existing as a monomer (human IL-12p40) and as a homodimer (human IL-12p80) and the antibody inhibits the binding of human IL-12 to human IL-12R β2 and human IL-23 to human IL-23R but does not inhibit the binding of human IL-12 or human IL-23 or human IL-12p40 or human IL-12p80 to human IL-12Rβ1.10-27-2011

Adam William Clarke, New South Wales AU

Patent application numberDescriptionPublished
20110319597VARIANT DOMAIN ANTIBODIES - The present invention relates to domain antibodies which have modified framework regions such that the potency or level of binding of the domain antibody is improved. In particular the present invention relates to domain antibodies which bind TNFa in which changes have been made to framework sequences and to constructs including these domain antibodies.12-29-2011

Bryan Charles Clarke, Pearce AU

Patent application numberDescriptionPublished
20110281818HIGH FRUCTAN CEREAL PLANTS - The invention provides cereal plants having a high level of fructan useful for the production of a range of food, beverage, nutraceutical and pharmaceutical products. The invention provides methods of producing high-fructan products from plants modified to comprise a reduced level of an endogenous polypeptide with starch synthase activity, and products so produced. In some embodiments, plants are modified by introduction of an agent such as a nucleic acid molecule which down regulates endogenous starch synthase II gene expression.11-17-2011

David John Clarke, Chartwell AU

Patent application numberDescriptionPublished
20110232159Biodiesel Additive - The invention provides an additive for lowering the minimum usable temperature of a biodiesel fuel or a diesel/biodiesel blend. The additive comprises at least one saccharide ester and a polymer having a comb structure. In some instances there is only one saccharide ester present. In this case the saccharide ester comprises at least one saturated ester group and at least one unsaturated ester group. In other instances, there is more than one saccharide ester is present. In these cases the additive comprises a first saccharide ester comprising at least one saturated ester group and a second saccharide ester comprising at least one unsaturated ester group.09-29-2011

Gayle Clarke, South Australia AU

Patent application numberDescriptionPublished
20090009714Apparatus and Method For Assement and Rehabilitation After Acquired Brain Injury - The present invention relates to an apparatus and method for the assessment and rehabilitation of vision impairment. In particular, the invention is concerned with an apparatus displaying visual stimuli and the method of using this device for the purpose of assessment and rehabilitation of individuals with acquired brain injury and visual impairment resulting therefrom. The apparatus comprises a display means with a plurality of visual stimuli switched on and off in predetermined sequences. The sequences are adapted to be used to assess and rehabilitate a person's visual impairment.01-08-2009

Ian Wesley Robert Clarke, New South Wales AU

Patent application numberDescriptionPublished
20090025626Fluid Flow Indicator - A fluid flow indicator for observation of low flow rates in liquids includes a capillary tube (01-29-2009

Kenneth Paul Clarke, Victoria AU

Patent application numberDescriptionPublished
20090028554METHOD AND APPARATUS FOR SAMPLED OPTICAL SIGNAL MONITORING - Monitoring an optical signal comprises sampling the optical signal from two or more distinct tap points to retrieve a sample set. Multiple such sample sets are obtained over time. A joint probability distribution or phase portrait of the sample sets is assessed for indications of optical signal quality. The tap distinction can be polarisation, for example to determine OSNR, or frequency. The tap distinction can be a time delay, which can enable diagnostic differentiation between multiple impairments, such as OSNR, dispersion, PMD, jitter, Q, and the like. Machine learning algorithms are particularly suitable for such diagnosis, particularly when provided a two dimensional histogram of sample density in the phase portrait.01-29-2009
20100042559METHOD AND APPARATUS FOR AUTOMATED IDENTIFICATION OF SIGNAL CHARACTERISTICS - A method of assessing a signal to identify particular signal characteristics comprises application of machine learning to multi-dimensional histograms derived from multi-tap sampling of the signal. The signal is sampled from at least two tap points to retrieve a sample set, and the at least two tap points are adapted to retrieve distinct samples from the signal, such as time spaced samples or spectrally distinct samples. Multiple sample sets are retrieved from the signal over time. The at least two dimensional histogram is built from the joint probability distribution of the plurality of sample sets. A machine learning algorithm then processes the multi-dimensional histogram, and is trained to predict a value of at least one characteristic of the signal.02-18-2010

Michael P. Clarke, Ellenbrook AU

Patent application numberDescriptionPublished
20090150348MANAGING DATA PRODUCED FROM DISCOVERIES CONDUCTED AGAINST SYSTEMS - Method, system, and computer program product for managing output reports produced from discoveries conducted against systems are provided. A discovery is conducted against a system to produce one or more output reports relating to configuration of the system. A signature is calculated for each output report. A determination is made as to whether each output report has a corresponding saved output report in a collection of saved output reports produced from one or more previously conducted discoveries against the system. For each output report having a corresponding saved output report, the signature for the output report is compared to a signature for the corresponding saved output report. In response to the signature for the output report being different from the signature for the corresponding saved output report, the corresponding saved output report in the collection of saved output reports is replaced with the output report.06-11-2009

Michael Paul Clarke, Ellenbrook AU

Patent application numberDescriptionPublished
20090094608METHOD AND APPARATUS FOR MOVING A SOFTWARE APPLICATION IN A SYSTEM CLUSTER - In one aspect, the invention is directed to a method for shutting down a first instance of an application and starting up a second instance of the application. The first instance of the application has associated therewith at least one first-instance support resource. The second instance of the application has associated therewith at least one second-instance support resource. The method includes: 04-09-2009
20090158016USE OF MODES FOR COMPUTER CLUSTER MANAGEMENT - A system, method and computer program product for managing a plurality of applications in a computer cluster. Each application is able to run on a particular node in the cluster. In one embodiment, associations are maintained among a plurality of modes and the plurality of applications, with each application being associated with at least one mode. Responsive to designation of at least one mode as active for the cluster, each application that is associated with an active mode is flagged as eligible for activation, each inactive application that is not associated with any active mode is flagged as ineligible for activation, and each active application that is not associated with any active mode is flagged as ineligible for activation and inactivated. Flagging as eligible, flagging as ineligible and flagging as ineligible and inactivating may be performed in any order, and inactivating is sequenced according to dependencies among the applications.06-18-2009
20110225103EFFICIENCY OF COMPUTER MODELING AND ANALYSIS OF COMPLEX PROCESSES - A system and method for constructing and analyzing a graphical representation of a complex process comprises steps and means for receiving input of content related to the complex process; processing said input to identify entities and actions instrumental in the execution of the complex process; constructing a graphical representation of the process as a network comprising first nodes, representing decision points, second nodes representing primary stakeholders and actions providing direct input to decision making points, and leaves representing secondary stakeholders providing indirect input to decision making points; and applying at least one analytic approach for evaluating the decision points of the graphical representation of the process.09-15-2011

Murray Clarke, Drummoyne AU

Patent application numberDescriptionPublished
20100163506STORAGE RACK BEAM - A storage rack beam includes top and bottom flanges and at least one web that interconnects the flanges. The web includes at least one stiffening formation arranged to stiffen an intermediate region of the web along at least a substantial portion of its length so as to resist lateral loading applied to the beam. The racking beam may take various forms, including first and second U-shaped sections in opposed abutting relationship, or formed as a closed S-shaped profile. Also disclosed is a storage rack beam that has a vertical loading capacity and a horizontal loading capacity, wherein at least part of the horizontal loading capacity is independent of the vertical loading capacity applied to the beam.07-01-2010

Nicholas Edward Clarke, Penrith AU

Patent application numberDescriptionPublished
20090255838SYRINGE DISPOSAL DEVICE - The present invention discloses a syringe disposal device (10-15-2009
20100276319SYRINGE DISPOSAL DEVICE - The present invention discloses a syringe disposal device (11-04-2010

Robert John Clarke, Heathpool AU

Patent application numberDescriptionPublished
20110204148DEVICE HAVING DATA STORAGE - The present invention relates to the field of devices which store data for a period of time. In one form, the invention relates to devices which store data in which the data store is subject to periodic and/or relatively short power outages. In one example, the invention relates to a radio frequency identification (“RFID”) transponder, and more particularly to a RFID transponder that is used in orientation independent applications. Other applications of the present invention are to devices used where supply power is intermittent. In a first aspect of embodiments described herein there is provided a.method of and/or device comprising a memory adapted to store data, a supply of power adapted to provide supply power to the memory, a path of leakage, the leakage path serving, over time, to diminish the integrity of data stored in the memory, and a leakage attenuator adapted to selectively attenuate the rate of leakage.08-25-2011

Robin Edward Clarke, Elwood AU

Patent application numberDescriptionPublished
20080199739Electrochemical cell stack and a method of forming a bipolar interconnect for an electrochemical cell stack - A method of forming a bipolar interconnect for a polymer electrolyte membrane fuel cell or electrolyser stack. The method includes providing a planar electrically-conductive blank, and deforming a portion of the conductive blank to provide a raised part on the blank defining an electrical contact and a fluid flow channel.08-21-2008
20080199752Electrochemical stack with pressed bipolar plate - An electrochemical cell having a central active area and a perimeter area, the electrochemical cell including: a membrane electrode assembly (MEA) having a first electrode, a proton exchange membrane, and a second electrode of opposite electrical polarity to the first electrode; a pressed metal interconnect having on a first side a raised portion in electrical contact with the first electrode; the interconnect and the first electrode defining at least one fluid channel between the interconnect and the first electrode in the central active area, such that a fluid conveyed in the fluid channel is in fluid communication with the first electrode; a gasket interposed between the membrane and the interconnect in the perimeter area, such that the fluid is sealed within the fluid channel; and a fluid opening in the gasket allowing fluid communication between the fluid channel and a manifold in the perimeter area.08-21-2008

Rodney Clarke, Victoria AU

Patent application numberDescriptionPublished
20100281601CONVERTIBLE GARMENTS - A convertible garment with legs (11-11-2010

Stephen Clarke, Morphett Vale AU

Patent application numberDescriptionPublished
20110232159Biodiesel Additive - The invention provides an additive for lowering the minimum usable temperature of a biodiesel fuel or a diesel/biodiesel blend. The additive comprises at least one saccharide ester and a polymer having a comb structure. In some instances there is only one saccharide ester present. In this case the saccharide ester comprises at least one saturated ester group and at least one unsaturated ester group. In other instances, there is more than one saccharide ester is present. In these cases the additive comprises a first saccharide ester comprising at least one saturated ester group and a second saccharide ester comprising at least one unsaturated ester group.09-29-2011

Terence Andrew Clarke, Queensland AU

Patent application numberDescriptionPublished
20100126188EXCHANGEABLE AIR-CONDITIONING UNIT - An exchangeable air-conditioning unit (05-27-2010

Terrence Peter Clarke, North Beach AU

Patent application numberDescriptionPublished
20100295359Collapsible Cushion - A method of mining a valuable metal or material in an ore body is described. The method comprises the steps of: a) placing a cushion in a stope whereby the cushion creates a void into which fragmented rock can expand during subsequent blasting operations for a second or subsequent panel; and, b) maintaining the void until blasting operations occur whereupon the void is caused to collapse to accommodate fragmented ore generated during blasting operations.11-25-2010

William Severn Clarke, Mt Macedon AU

Patent application numberDescriptionPublished
20110092726System for cultivation and processing of microorganisms, processing of products therefrom, and processing in drillhole reactors - Described are methods of cultivating autotrophic microorganisms, particularly microalgae or diatoms, in a bioreactor by entraining a culture of the microorganisms in a tenuous, gelated, thixotrophic carrier medium having nutrients therefor and moving the medium along a passage at a sufficiently slow speed to enable laminar flow which in cross section is closed and which has transparent walls through which the culture is irradiated to enable photosynthesis. The method includes effecting convective turnover of the culture and medium as they flow along the passage by differentially heating the medium laterally relative to the flow direction so as to produce a generally helical flow of the culture and medium. Also described are processing methods, both physical and chemical, performed underground e.g. in drillholes, to utilise decavitation energy under ambient elevated pressures, including processes to implement lysis of the micro-organisms, producing methanol, syngas synthesis, Haber ammonia synthesis, Fischer-Tropsch reactions, supercritical reactions, dimethyl ether synthesis, and nitric acid synthesis.04-21-2011