Claas
Andreas Claas, Saffron Walden GB
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20130203047 | Increasing Confidence of Allele Calls with Molecular Counting - Aspects of the present invention include methods and compositions for determining the number of individual polynucleotide molecules originating from the same genomic region of the same original sample that have been sequenced in a particular sequence analysis configuration or process. In these aspects of the invention, a degenerate base region (DBR) is attached to the starting polynucleotide molecules that are subsequently sequenced (e.g., after certain process steps are performed, e.g., amplification and/or enrichment). The number of different DBR sequences present in a sequencing run can be used to determine/estimate the number of different starting polynucleotides that have been sequenced. DBRs can be used to enhance numerous different nucleic acid sequence analysis applications, including allowing higher confidence allele call determinations in genotyping applications. | 08-08-2013 |
20130267424 | Method of tagging using a split DBR - Aspects of the present invention include methods and compositions for determining the number of individual polynucleotide molecules originating from the same genomic region of the same original sample that have been sequenced in a particular sequence analysis configuration or process. In these aspects of the invention, a degenerate base region (DBR) is attached to the starting polynucleotide molecules that are subsequently sequenced (e.g., after certain process steps are performed, e.g., amplification and/or enrichment). The number of different DBR sequences present in a sequencing run can be used to determine/estimate the number of different starting polynucleotides that have been sequenced. DBRs can be used to enhance numerous different nucleic acid sequence analysis applications, including allowing higher confidence allele call determinations in genotyping applications. | 10-10-2013 |
20150031559 | Increased Confidence of Allele Calls with Molecular Counting - Aspects of the present invention include methods and compositions for determining the number of individual polynucleotide molecules originating from the same genomic region of the same original sample that have been sequenced in a particular sequence analysis configuration or process. In these aspects of the invention, a degenerate base region (DBR) is attached to the starting polynucleotide molecules that are subsequently sequenced (e.g., after certain process steps are performed, e.g., amplification and/or enrichment). The number of different DBR sequences present in a sequencing run can be used to determine/estimate the number of different starting polynucleotides that have been sequenced. DBRs can be used to enhance numerous different nucleic acid sequence analysis applications, including allowing higher confidence allele call determinations in genotyping applications. | 01-29-2015 |
Andreas Claas, Essex GB
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20130210643 | Method for preparing a counter-tagged population of nucleic acid molecules. - Aspects of the present invention include methods and compositions for determining the number of individual polynucleotide molecules originating from the same genomic region of the same original sample that have been sequenced in a particular sequence analysis configuration or process. In these aspects of the invention, a degenerate base region (DBR) is attached to the starting polynucleotide molecules that are subsequently sequenced (e.g., after certain process steps are performed, e.g., amplification and/or enrichment). The number of different DBR sequences present in a sequencing run can be used to determine/estimate the number of different starting polynucleotides that have been sequenced. DBRs can be used to enhance numerous different nucleic acid sequence analysis applications, including allowing higher confidence allele call determinations in genotyping applications. | 08-15-2013 |
20130224743 | Method for accurately counting starting molecules - Aspects of the present invention include methods and compositions for determining the number of individual polynucleotide molecules originating from the same genomic region of the same original sample that have been sequenced in a particular sequence analysis configuration or process. In these aspects of the invention, a degenerate base region (DBR) is attached to the starting polynucleotide molecules that are subsequently sequenced (e.g., after certain process steps are performed, e.g., amplification and/or enrichment). The number of different DBR sequences present in a sequencing run can be used to determine/estimate the number of different starting polynucleotides that have been sequenced. DBRs can be used to enhance numerous different nucleic acid sequence analysis applications, including allowing higher confidence allele call determinations in genotyping applications. | 08-29-2013 |
20130237458 | Method of adding a DBR by primer extension - Aspects of the present invention include methods and compositions for determining the number of individual polynucleotide molecules originating from the same genomic region of the same original sample that have been sequenced in a particular sequence analysis configuration or process. In these aspects of the invention, a degenerate base region (DBR) is attached to the starting polynucleotide molecules that are subsequently sequenced (e.g., after certain process steps are performed, e.g., amplification and/or enrichment). The number of different DBR sequences present in a sequencing run can be used to determine/estimate the number of different starting polynucleotides that have been sequenced. DBRs can be used to enhance numerous different nucleic acid sequence analysis applications, including allowing higher confidence allele call determinations in genotyping applications. | 09-12-2013 |
David Claas, San Diego, CA US
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20120065314 | COMPOSITION AND MANUFACTURING METHODS FOR GRIPS - A composition for use in grips is disclosed. The composition may be used, for example, in making a golf club grip. The disclosed grip provides for improved shock absorption and other beneficial properties. In one embodiment the comprises a cross-linked composition of from about 40% by weight to about 80% by weight of one or a combination of a first material selected from the group consisting of butyl rubber, nitrile rubber, ethylene propylene rubber and chloroprene rubber, and from about 10% by weight to about 50% by weight of one or a combination of a second material selected from the group consisting of ethylene-propylene-diene copolymer (EPDM), polyurethane, ethylene-vinyl acetate copolymer, polypropylene and cork. | 03-15-2012 |
20130035436 | COMPOSITION AND MANUFACTURING METHODS FOR GRIPS - A composition for use in grips is disclosed. The composition may be used, for example, in making a golf club grip. The disclosed grip provides for improved shock absorption and other beneficial properties. In one embodiment the comprises a cross-linked composition of from about 40% by weight to about 80% by weight of one or a combination of a first material selected from the group consisting of butyl rubber, nitrile rubber, ethylene propylene rubber and chloroprene rubber, and from about 10% by weight to about 50% by weight of one or a combination of a second material selected from the group consisting of ethylene-propylene-diene copolymer (EPDM), polyurethane, ethylene-vinyl acetate copolymer, polypropylene and cork. | 02-07-2013 |
Han Claas, Taipei City TW
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20110280113 | Optical Storage System and Method for Writing Data to an Optical Disc - The invention relates to an optical data system comprising an optical disc drive and a host. The optical disc drive is arranged to receive an optical disc and perform read and write actions with respect to the optical disc. The host is arranged to instruct the optical disc drive to perform a read or write action with respect to the optical disc. The optical disc drive may be arranged to | 11-17-2011 |
James Claas, Watertown, WI US
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20090289126 | Fluid activated nozzle - A nozzle assembly for use in spraying a fluid. The nozzle assembly includes a nozzle portion, a base portion, and a plurality of elastic bellows disposed between the nozzle portion and the base portion. The bellows are coupled to both the nozzle portion and the base portion. Movement of the nozzle is achieved by activation of the bellows. | 11-26-2009 |
Johannes Francicus Petrus Claas, Taipei City TW
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20100067348 | Record Carrier as well as an Apparatus and Method for Applying Image Data as a Visually Detectable Pattern at an Optical Record Carrer - A method of applying image data as a visually detectable pattern with at least one embedded data element at an optical record carrier is disclosed, comprising the step of physically mapping at least one channel symbol onto the record carrier, the channel symbol being selected from a set of mutually different channel symbols, the channel symbols each comprising an area of size s | 03-18-2010 |
20100067349 | Optical Record Carrier as well as an Apparatus and Method for Reading/Writing Image Data from/at a Visually Detectable Pattern at an Optical Record Carrier - A method is disclosed of reading an image data from an optical record carrier with a visually detectable pattern comprising a visually detectable pattern of pixels comprising at least one pattern element comprising an area of size s | 03-18-2010 |
Johannes Franciscus Claas, Eindhoven NL
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20090252010 | OPTICAL DISK DRIVE WITH DISK TYPE DETERMINATION AND METHOD OF DETERMINING A DISK TYPE OF AN OPTICAL DISK WITH AN OPTICAL DISK DRIVE - An optical disk drive and a method for determining a disk type are described. The optical disk drive may be arranged to receive a radial error signal while an incident beam is focused onto the optical disk and before tracking the track, to analyze the radial error signal for detecting whether a wobble signal is present, indicating whether the track is wobbled, and to derive a disk type from the wobble signal, if present. The optical disk drive may additionally or alternatively be arranged to receive a central aperture signal while the incident beam is focused onto the optical disk and before tracking a track including a sequence of embossed pits, to analyze the signal amplitude of the central aperture signal, and to determine the disk type from at least a first variation of the signal amplitude of the central aperture signal as a function of time. | 10-08-2009 |
Johannes Franciscus Peterus Claas, Hsinchu TW
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20100315925 | METHOD FOR DISCRIMINATING DISC - A disc discriminating method for use in an optical disc drive includes the following steps. Firstly, an optical pickup head of the optical disc drive is controlled to move in a first direction when the optical pickup head is in a track-unlocked state. Then, a tracking error signal and a radio frequency signal are generated. According to the tracking error signal, a tracking error zero crossing signal is obtained. According to the radio frequency signal, a radio frequency zero crossing signal is obtained. According to a phase relation between the tracking error zero crossing signal and the radio frequency zero crossing signal, the disc is discriminated as an on-groove recording disc or an in-groove recording disc. | 12-16-2010 |
Johannes Franciscus Petrus Claas, Hsinchu TW
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20110155002 | LABELING METHOD FOR BLU-RAY DISC - The present invention provides a labeling method for a blu-ray disc, which includes following steps: an initial radius is selected on a blank area of the blu-ray disc, and a pattern is determined; an initial physical sector number is calculated using the initial radius, and the pattern is transformed into a description data; according to the initial physical sector number and a size of the description data, a sequential recorded region of the blu-ray disc is divided into at least two sequential recorded regions, and information of the at least two sequential recorded regions are updated in a table of content, wherein an initial position of one of the sequential recorded regions is the initial physical sector number, and a length of the one of the sequential recorded regions is the size of the description data; the description data is written from the initial physical sector number. | 06-30-2011 |
Johannes Franciscus Petrus Claas, Valkenswaard NL
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20090059739 | METHOD OF WRITTING DATA TO A DISC, DISC DRIVE - The invention relates to a method of writing data to a disc (OD). The method comprised: a) performing a plurality of writing actions in which a plurality of data portions are written to the disc, b) performing a plurality of verification actions in which written data portions are at least partly verified and at least part of the data portions are replaced if needed. The method further comprises a2) performing a decision action for each writing action in which a decision whether or not to perform the verification action for a specific written data portion is taken. | 03-05-2009 |
20090059750 | METHOD OF WRITING DATA TO A DISC, DISC DRIVE - The invention relates to a method of writing data to a disc (OD). The method comprising a) performing a writing action in which a first data portion is written to the disc; a2) deciding to perform b) or not and b) verifying at least part of the first data portion that is written to the disc and deciding to replace the first data portion that is written to the disc or not. Finally the method comprises c) performing a further writing action in which a second data portion is written to the disc. | 03-05-2009 |
20120087223 | METHOD OF WRITING DATA TO A DISC, DISC DRIVE - The invention relates to a method of writing data to a disc (OD). The method comprised: a) performing a plurality of writing actions in which a plurality of data portions are written to the disc, b) performing a plurality of verification actions in which written data portions are at least partly verified and at least part of the data portions are replaced if needed. The method further comprises a2) performing a decision action for each writing action in which a decision whether or not to perform the verification action for a specific written data portion is taken. | 04-12-2012 |
Robert C. Claas, Saukville, WI US
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20100101446 | RAILWAY ANCHOR APPLICATOR - A railway anchor applicator for applying an anchor to a rail includes a frame configured for movement along a track, an anchor input for sequentially delivering an anchor to a workhead assembly, where the workhead assembly is movably mounted on the frame for movement toward and away from the rail. An anchor receiving arm is configured for movement between a first position receiving an anchor from an anchor input and a second position placing the anchor away from the anchor input. A main pivot arm is configured for movement between a first position generally away from the rail and a second position generally adjacent the rail. A bar clamp arm is operatively linked to the main pivot arm and is configured for movement underneath the rail, then upwards and towards the rail. An operator station is located on the gage side of the rail which the anchor is being applied. | 04-29-2010 |