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| 20090269396 | DUAL ACTION, INHALED FORMULATIONS PROVIDING BOTH AN IMMEDIATE AND SUSTAINED RELEASE PROFILE - Methods for formulating immediate and sustained release anti-infectives and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described. | 10-29-2009 |
| 20090274754 | DUAL ACTION, INHALED FORMULATIONS PROVIDING BOTH AN IMMEDIATE AND SUSTAINED RELEASE PROFILE - Methods for formulating immediate and sustained release anti-infectives and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described. | 11-05-2009 |
| 20100209538 | PH-MODULATED FORMULATIONS FOR PULMONARY DELIVERY - An aerosolizable formulation comprised of a drug, a carrier and pH affecting component is disclosed. The drug is dissolved in the formulation at a concentration above which it remains in solution at neutral pH. This increases the concentration of the drug in solution making it possible to administer larger amounts of drug with the same or a smaller volume of formulation. When the formulation is aerosolized to small particles and inhaled into human lungs in small volumes (e.g. 0.05 to 0.5 mL) the fluids in the lungs neutralize the formulation causing the drug to participate out of solution. This results in the drug being delivered at a controlled rate below the rate at which drug is administered from a formulation initially at a neutral pH. | 08-19-2010 |
| 20110064796 | CONCENTRATED, INHALABLE ANTIBIOTIC FORMULATION - A concentrated inhalable formulation of an antibiotic drug such as ciprofloxacin is disclosed. The antibiotic is formulated with sodium acetate and liposome which incorporate antibiotic. The formulation is aerosolized and inhaled for treatment of respiratory tract infections and other medical conditions. | 03-17-2011 |
| 20110104259 | PROCESSES FOR TASTE-MASKING OF INHALED FORMULATIONS - The present invention provides novel processes and methodologies to minimize the bitter or otherwise unpleasant taste, to minimize the tendency to stimulate the cough reflex, or to minimize oropharyngeal deposition of medically-active compounds administered by the pulmonary/inhalation route and to deliver hydroxychloroquine (HCQ) either singularly or in combination with an antimalarial and aminoquinolone by the pulmonary/inhalation route in a sustained release or other formulation that minimizes the bitter or otherwise unpleasant taste of HCQ or any potential to stimulate the cough reflex, and to deliver a dopaminergic compound or its prodrug, including ABT-431 by the pulmonary/inhalation route in a sustained release or other formulation that minimizes the unpleasant taste of the drug or any potential to stimulate the cough reflex, and to deliver a lantibiotic, including duramycin by the pulmonary/inhalation route in a sustained release or other formulation that minimizes the unpleasant taste of the drug or any potential to stimulate throat irritation. | 05-05-2011 |
| 20110150983 | CONCENTRATED, INHALABLE CIPROFLOXACIN FORMULATION - A concentrated inhalable formulation of an antibiotic drug such as ciprofloxacin is disclosed. The antibiotic is formulated with sodium acetate and liposomes which incorporate antibiotic. The formulation is aerosolized and inhaled for treatment of respiratory tract infections and other medical conditions. | 06-23-2011 |
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| 20090197001 | FLUID APPLICATOR ASSEMBLY - A low pressure fluid applicator assembly includes a frame having a first roller mounting location and a second roller mounting location spaced from the first roller mounting location such that first and second rollers can mount to the frame having their central axes spaced from one another. The frame includes first and second side rails selectively connected to one another by a strut that is not integrally formed with at least one of the first and second side rails. A fluid supply member is connected to the frame and spaced from the first roller mount. The fluid supply tube is adapted to communicate with an associated fluid source. | 08-06-2009 |
| 20100139033 | Dual Stage Cyclonic Dust Collector - A surface cleaning suction type appliance comprises a housing, an airstream suction source, a cyclone main body, and a dirt cup. The housing includes a main suction opening. The airstream suction source is mounted to the housing and includes a suction airstream inlet and a suction airstream outlet. The suction source selectively establishes and maintains a flow of air from the main suction opening, via the airstream inlet, to the airstream outlet. The cyclone main body is supported by the housing and is in communication with the main suction opening. The cyclone main body has a uniform outer circumference and includes a first stage separator, and a plurality of downstream second stage separators. The lengths of the second stage cyclonic separators are different for any number of adjacent pairs of separators from on pair up to all adjacent pairs of separators. The dirt cup is connected to the cyclone main body. The dirt cup includes a first particle collector and a second particle collector. The first particle collector communicates with the first stage separator for collecting dust particles from the first stage separator. The separate second particle collector communicates with the plurality of second stage separators for collecting dust particles from the second stage separators. | 06-10-2010 |
| 20110013968 | FLUID APPLICATOR ASSEMBLY - A fluid applicator assembly includes an applicator device and a pumping device. In one embodiment, the applicator device includes a frame, a fluid supply passage connected with the frame, and a handle connected to the frame. The frame includes a first roller mount in a first roller axis and a second roller mount in a second roller axis that is spaced from the first roller axis. The fluid supply passage connects with the frame and includes a fluid outlet arranged for dispensing fluid onto an external surface of at least one of the first and second rollers. The handle connects to the frame and is rotatable with respect to the frame and a handle pivot axis that is offset from the first roller axis and the second roller axis. The pumping device, in a housing in a pump disposed in the housing and in communication with the fluid supply passage. | 01-20-2011 |
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| 20080289139 | DUAL STAGE CYCLONIC VACUUM CLEANER - A home cleaning appliance comprises a housing, an airstream suction source, a cyclone main body, and a dirt cup. The housing includes a main suction opening. The airstream suction source is mounted to the housing and includes a suction airstream inlet and a suction airstream outlet. The suction source selectively establishes and maintains a flow of air from the main suction opening, via the airstream inlet, to the airstream outlet. The cyclone main body is supported by the housing and is in communication with the main suction opening. The cyclone main body has a uniform outer circumference and includes a first stage separator, and a plurality of downstream second stage separators. The first stage separator has a longitudinal axis offset from a longitudinal axis of the cyclone main body in order to accommodate the second stage separators. The dirt cup is connected to the cyclone main body. The dirt cup includes a first particle collector and a second particle collector. The first particle collector communicates with the first stage separator for collecting dust particles from the first stage separator. The separate second particle collector communicates with the plurality of second stage separators for collecting dust particles from the second stage separators. | 11-27-2008 |
| 20110219578 | BAG RELEASE HANDLE FOR A FLOOR CLEANER - A floor cleaner including a nozzle and a handle assembly pivotably mounted to the nozzle. The handle assembly including a handle, a motor housing supporting a suction source in fluid communication with the nozzle, and a bag housing defining a filter cavity. A door is removably coupled to the handle assembly and includes a retainer configured to secure a filter bag including a bag aperture to the door such that the door and the retainer are removable from the handle assembly as an assembly. The retainer includes a retainer handle positioned above the bag aperture. | 09-15-2011 |
| 20110219582 | INTEGRATED BAG DOOR AND CARRY HANDLE FOR A FLOOR CLEANER - A floor cleaner including a nozzle and a handle assembly pivotably mounted to the nozzle. The handle assembly including a handle, a motor housing supporting a suction source in fluid communication with the nozzle, and a bag housing. A door is removably coupled to the bag housing and includes a door handle and a filter bag retaining structure. | 09-15-2011 |
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| 20090120950 | CENTER-PULL PAPER TOWEL DISPENSER - A center-pull dispenser for dispensing paper towels from a continuous roll, wherein each individual towel is separated from an adjoining towel by a plurality of perforations. The dispenser comprises a housing having a housing back and a detachable front cover hingedly connected thereto at the lower periphery of said housing back and front cover for opening and closing the housing, a paper support tray removably connected to a lower portion of the housing back and having a centrally located dispensing nozzle, an opening in the lower periphery of the housing through which the towels are dispensed, a detachable wall-mounting member for removably mounting the housing back to a wall, and a locking member for releasably locking the front cover to the housing back and the housing back to the wall-mounting member. In one embodiment, the housing cannot be removed from the wall-mounting member without first unlocking the locking member, and the housing and the housing back are removable from the wall without removing the wall-mounting member from the wall. In another embodiment, the paper support tray comprises locking arms for releasably locking first hinge elements on the lower periphery of said front cover against second hinge elements on the lower periphery of said housing back. | 05-14-2009 |
| 20090120951 | CENTER-PULL PAPER TOWEL DISPENSER - A center-pull dispenser for dispensing paper towels from a continuous roll, wherein each individual towel is separated from an adjoining towel by a plurality of perforations. The dispenser comprises a housing having a housing back and a detachable front cover hingedly connected thereto at the lower periphery of said housing back and front cover for opening and closing the housing, a paper support tray removably connected to a lower portion of the housing back, the tray having a centrally located dispensing nozzle and at least one locking element for releasably locking at least one first hinge element on the lower periphery of the front cover to at least one second hinge element on the lower periphery of the housing back, an opening in the lower periphery of said housing through which the towels are dispensed, and a wall-mounting member for removably mounting the housing back to a wall. In one embodiment, the paper support tray comprises locking arms for releasably locking first hinge elements on the lower periphery of said front cover against second hinge elements on the lower periphery of said housing back. In another embodiment, the dispenser comprises a locking member for releasably locking the front cover to the housing back and the housing back to the wall-mounting member. | 05-14-2009 |
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| 20090006808 | ULTRASCALABLE PETAFLOP PARALLEL SUPERCOMPUTER - A novel massively parallel supercomputer of petaOPS-scale includes node architectures based upon System-On-a-Chip technology, where each processing node comprises a single Application Specific Integrated Circuit (ASIC) having up to four processing elements. The ASIC nodes are interconnected by multiple independent networks that optimally maximize the throughput of packet communications between nodes with minimal latency. The multiple networks may include three high-speed networks for parallel algorithm message passing including a Torus, collective network, and a Global Asynchronous network that provides global barrier and notification functions. These multiple independent networks may be collaboratively or independently utilized according to the needs or phases of an algorithm for optimizing algorithm processing performance. Novel use of a DMA engine is provided to facilitate message passing among the nodes without the expenditure of processing resources at the node. | 01-01-2009 |
| 20090277616 | METHOD AND APPARATUS OF WATER COOLING SEVERAL PARALLEL CIRCUIT CARDS EACH CONTAINING SEVERAL CHIP PACKAGES - A cooling or heat transfer apparatus and method is disclosed for cooling an electronic device. The apparatus includes a heat producing electronic device which may include an electronic circuit card with many heat sources. A heat transfer device is connected to the heat producing electronic device which is thermally communicating with the heat producing device for transferring heat from the heat producing device to the heat transfer device. A heat conduit is connected to the heat transfer device and thermally communicating with the heat transfer device for transferring heat to the heat conduit from the heat transfer device. A cooling housing is connected to the heat conduit and the cooling housing thermally communicating with the heat conduit for transferring heat to the cooling housing from the heat conduit. The apparatus enables the replacement of circuit cards in the field because it eliminates the need to apply thermal-interface materials. | 11-12-2009 |
| 20090303681 | COINED-SHEET-METAL HEATSINKS FOR CLOSELY PACKAGED HEAT-PRODUCING DEVICES SUCH AS DUAL IN-LINE MEMORY MODULES (DIMMs) - A heatsink structure and method for the cooling of closely spaced packaged heat-producing devices, such as dual-in-line memory modules (DIMMs). A folded sheet metal heatsink structure is provided which is constituted of a coined metallic material and which has a large plurality of waffle-shaped ridges extending therefrom constituting additional surface areas which are adapted to enable heat generated by hub chips to pass upwardly and then outwardly through waffle-like ridges and, thus, dissipated to the exterior, thereby imparting an improved degree of cooling to heat-producing components or devices. | 12-10-2009 |
| 20100025010 | APPARATUS AND METHOD OF DIRECT WATER COOLING SEVERAL PARALLEL CIRCUIT CARDS EACH CONTAINING SEVERAL CHIP PACKAGES - A cooling apparatus, system and like method for an electronic device includes a plurality of heat producing electronic devices affixed to a wiring substrate. A plurality of heat transfer assemblies each include heat spreaders and thermally communicate with the heat producing electronic devices for transferring heat from the heat producing electronic devices to the heat transfer assemblies The plurality of heat producing electronic devices and respective heat transfer assemblies are positioned on the wiring substrate having the regions overlapping. A heat conduit thermally communicates with the heat transfer assemblies. The heat conduit circulates thermally conductive fluid therethrough in a closed loop for transferring heat to the fluid from the heat transfer assemblies via the heat spreader. A thermally conductive support structure supports the heat conduit and thermally communicates with the heat transfer assemblies via the heat spreader transferring heat to the fluid of the heat conduit from the support structure. | 02-04-2010 |
