Chun Zhang
Chun Zhang, Shanghai CN
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20110078327 | Content delivery utilizing multiple content delivery networks - Content delivery includes receiving a Domain Name Service (DNS) request, selecting from a plurality of Content Delivery Networks (CDNs) a CDN to provide content associated with the DNS request, processing the DNS request and generating a response, the response including a canonical name (CNAME) value that corresponds to the selected CDN, receiving an indication that the content is not presently available at the selected CDN, and returning an Internet Protocol (IP) address of a data source that is configured to provide the content to the selected CDN. | 03-31-2011 |
Chun Zhang, San Jose, CA US
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20080222087 | System and Method for Optimizing Query Access to a Database Comprising Hierarchically-Organized Data - An cost based optimizer optimizes access to at least a portion of hierarchically-organized documents, such as those formatted using eXtensible Markup Language (XML), by estimating a number of results produced by the access of the hierarchically-organized documents. Estimating the number of results comprises computing the cardinality of each operator executing query language expressions and further computing a sequence size of sequences of hierarchically-organized nodes produced by the query language expressions. Access to the hierarchically-organized documents is optimized using the structure of the query expression and/or path statistics involving the hierarchically-organized data. The cardinality and the sequence size are used to calculate a cost estimation for execution of alternate query execution plans. Based on the cost estimation, an optimal query execution plan is selected from among the alternate query execution plans. | 09-11-2008 |
20080263001 | SYSTEM AND METHOD FOR AUTOMATING DATA PARTITIONING IN A PARALLEL DATABASE - A system for automating data partitioning in a parallel database includes plural nodes connected in parallel. Each node includes a database server and two databases connected thereto. Each database server includes a query optimizer. Moreover, a partitioning advisor communicates with the database server and the query optimizer. The query optimizer and the partitioning advisor include a program for recommending and evaluating data table partitions that are useful for processing a workload of query statements. The data table partitions are recommended and evaluated without requiring the data tables to be physically repartitioned. | 10-23-2008 |
20100005077 | METHODS AND SYSTEMS FOR GENERATING QUERY PLANS THAT ARE COMPATIBLE FOR EXECUTION IN HARDWARE - Embodiments of the present invention generate and optimize query plans that are at least partially executable in hardware. Upon receiving a query, the query is rewritten and optimized with a bias for hardware execution of fragments of the query. A template-based algorithm may be employed for transforming a query into fragments and then into query tasks. The various query tasks can then be routed to either a hardware accelerator, a software module, or sent back to a database management system for execution. For those tasks routed to the hardware accelerator, the query tasks are compiled into machine code database instructions. In order to optimize query execution, query tasks may be broken into subtasks, rearranged based on available resources of the hardware, pipelined, or branched conditionally | 01-07-2010 |
20110060768 | Computer Software for Visualizing Genotyping Data - A computer system for visualizing recombination events in a group of individuals is provided. According to one aspect of the invention, high-density SNP genotype data is obtained from related individuals in a family. A pedigree is created, haplotypes are reconstructed and likely recombination breakpoints are identified with the use of publicly available computer programs. A software tool is then used facilitate the visualization of the recombination events in the family. | 03-10-2011 |
Chun Zhang, Ossining, NY US
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20080317217 | SYSTEM AND METHOD FOR DETERMINING AND OPTIMIZING RESOURCES OF A DATA PROCESSING SYSTEM UTILIZED BY A SERVICE REQUEST - A computer-implemented method for determining resources utilized by a service request in a data processing system. The method includes determining monitored relationship types from monitoring data, determining relationship domains, determining intra-domain relationships from relationships that are internal to the relationship domains and determining cross-domain relationships from the intra-domain relationships that are linked between pairs of the relationship domains, and determining resources utilized by the service request from the intra-domain and cross-domain relationships. The domains are derived from one of the relationship types that is monitored by a single monitoring application. | 12-25-2008 |
20090287744 | APPARATUS, SYSTEM AND METHOD FOR HEALTHCHECK OF INFORMATION TECHNOLOGY INFRASTRUCTURE BASED ON LOG DATA - A method and system for checking health of information technology infrastructure based on log data, in one aspect, collect log data non-intrusively from a production system, said log data at least associated with transactions occurring in the production system and resource utilization of the production system, normalize said log data into a plurality of log data types, perform data regression analysis using said plurality of log data types to estimate resources consumed by each of said transactions and throughput of each of said transactions, and use a queuing model to predict performance of the information technology infrastructure under various workloads. | 11-19-2009 |
20100005468 | BLACK-BOX PERFORMANCE CONTROL FOR HIGH-VOLUME THROUGHPUT-CENTRIC SYSTEMS - Throughput of a high-volume throughput-centric computer system is controlled by dynamically adjusting a concurrency level of a plurality of events being processed in a computer system to meet a predetermined target for utilization of one or more resources of a computer system. The predetermined target is less than 100% utilization of said one or more resources. The adjusted concurrency level is validated using one or more queuing models to check that said predetermined target is being met. Parameters are configured for adjusting the concurrency level. The parameters are configured so that said one or more resources are shared with one or more external programs. A statistical algorithm is established that minimizes total number of samples collected. The samples may be used to measure performance used to further dynamically adjust the concurrency level. A dynamic thread sleeping method is designed to handle systems that need only a very small number of threads to saturate bottleneck resources and hence are sensitive to concurrency level changes. | 01-07-2010 |
20130205023 | SYSTEM AND METHOD FOR DETERMINING AND OPTIMIZING RESOURCES OF DATA PROCESSING SYSTEM UTILIZED BY A SERVICE REQUEST - A computer-implemented method for determining resources utilized by a service request in a data processing system. The method includes determining monitored relationship types from monitoring data, determining relationship domains, determining intra-domain relationships from relationships that are internal to the relationship domains and determining cross-domain relationships from the intra-domain relationships that are linked between pairs of the relationship domains, and determining resources utilized by the service request from the intra-domain and cross-domain relationships. The domains are derived from one of the relationship types that is monitored by a single monitoring application. | 08-08-2013 |
Chun Zhang, Waltham, MA US
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20120071512 | 5-PYRIDIN-3-YL-1, 3-DIHYDRO-INDOL-2-ON DERIVATIVES AND THEIR USE AS MODULATORS OF ALDOSTERONE SYNTHASE AND/OR CYP11B1 - The present invention provides a compound of formula I; | 03-22-2012 |
20130296377 | Complement pathway modulators and uses thereof - The present invention provides a compound of formula I: | 11-07-2013 |
20140275175 | ORGANIC COMPOUNDS - The present invention provides a compound of formula I; | 09-18-2014 |
20150250767 | Complement pathway modulators and uses thereof - The present invention provides a compound of formula I: | 09-10-2015 |
20160024079 | Complement Factor B inhibitors and uses there of - The present invention provides a compound of formula (I): wherein X is N or CH, Y is NH, O or S, methods for manufacturing these compounds, and their uses as Factor B inhibitors for the treatment of conditions and diseases associated with complement alternative pathway activation such as age-related macular degeneration, diabetic retinopathy and related ophthalmic diseases. The present invention further provides pharmaceutical compositions and combinations of pharmacologically active agents. | 01-28-2016 |
Chun Zhang, Chongqing CN
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20120238496 | FUSION PROTEIN REGULATING PLASMA GLUCOSE AND LIPID, ITS PREPARATION METHOD AND USE - Provided is a fusion protein, which comprises human fibroblast growth factor 21 and glucagon-like-peptide-1 or its analogs. Also provided is the medicament composition comprising the fusion protein, which can be used for treating or preventing obesity, diabetes, hyperglycemia and hyperlipidemia etc. | 09-20-2012 |
Chun Zhang, Hong Kong HK
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20120247203 | RAPID RESPONSE RELATIVE HUMIDITY SENSOR USING ANODIC ALUMINUM OXIDE FILM - A rapid response relative humidity sensor based on nano-structured aluminum oxide thin film is disclosed. The main body of the sensor is an anodic aluminum oxide thin film of about 2-20 μm thick formed from an Al substrate which serves as one electrode. A porous metal layer of about 20-200 nm thick is formed over the anodic aluminum oxide thin film and functions as a second electrode. The alumina thin film contains nano-sized channels of about 10-100 nm in diameter, serving as a capacitive relative humidity sensor having high sensitivity and short response time. Thermal annealing at elevated temperature improves the linearity of the capacitance versus humidity curve, giving a full range humidity sensing range. Hysteresis and degradation are negligible for the humidity sensors. | 10-04-2012 |
20130273816 | AUTOMATIC POLISHING DEVICE FOR SURFACE FINISHING OF COMPLEX-CURVED-PROFILE PARTS - The present invention discloses an automatic polishing device and the method of using the device for the surface finishing of a workpiece such as complex-curved-profile parts. Automatic polishing is performed by mounting the workpiece on an apparatus which enables different orientations along multiple axes and immerging the workpiece in a controlled flow of abrasive slurry. The device of the present invention provides a uniform finish on free form surface. It is also precise, low cost, non-destructive, and non-polluting. | 10-17-2013 |
20150208957 | Transmission-Reflectance Swappable Raman Probe for Physiological Detections - A transmission-reflectance swappable Raman device and a method thereof are disclosed. The excitation light is selectively directed to the sample in one direction for generating the transmission Raman signal in transmission mode or in another direction for generating the reflectance Raman signal in reflectance mode. The content of an analyte in a sample can be determined by analyzing transmission and reflectance Raman signal. | 07-30-2015 |
Chun Zhang, Jiulongpo Chongqing CN
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20120269795 | HUMANIZED RECOMBINANT URICASE AND MUTANTS THEREOF - The present invention provides a humanized recombinant uricase and mutants thereof, wherein the humanized recombinant uricase is a chimeric protein which comprises amino acids of non-human mammal uricase and amino acids of human uricase. The humanized recombinant unease and mutants thereof have reduced immunogenicity in human, and can be used for the treatment of hyperuricemia and gout. | 10-25-2012 |
20120277154 | HOMODIMER OF INSULINOTROPIC PEPTIDE ANALOGUES AND METHOD FOR PREPARATION THEREOF AND USE THEREOF - Provided is a homodimer of insulinotropic peptide analogues and method for preparation thereof and use thereof, wherein the insulinotropic peptide analogue comprises GLP-1 and Exendin-4. The homodimer of insulinotropic peptide analogues of the invention is made by conjugating two identical insulinotropic peptide analogue molecules at the C-terminal Cys residues via disulfide bond or PEG molecule. The homodimer of insulinotropic peptide analogues of the invention has superior stability and biological activity in vivo, and prolonged half-life in the circulation, and can be used for the preparation of hypoglycemic drugs. | 11-01-2012 |
Chun Zhang, Hong Kong Sar CN
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20120316448 | BLOOD PRESSURE MEASURING DEVICE AND METHOD OF CALIBRATING THEREOF - The present invention is a blood pressure measuring device comprising an optical sensing unit adapted for detecting optical pulses at a plurality of locations on an external surface of a user. The device also comprises a processing unit coupled to the optical sensing unit for determining an optimal location from the plurality of locations based on the detected optical pulses and a pressure sensing unit adapted for detecting a pressure pulse of the user at a location of measurement. The present invention also discloses a method of measuring a blood pressure of a user using a blood pressure measurement device. The advantage of the present invention is that by using an optical sensing unit to locate the artery of the user, or to compensate the misalignment from the artery, the blood pressure is more accurately determined. With the calibration method, the deficient cuff calibration can be waived in certain circumstances. | 12-13-2012 |
20130303921 | System and Method for Measurement of Physiological Data with Light Modulation - The present invention discloses a device for measuring physiological data of a subject. It comprises a light modulation unit, an optical detection unit and a signal processing unit. The present invention can operate in an active mode or a passive mode to measure a subject's heart rate, respiratory information, haemoglobin level, cardiac output or oxygen saturation of the blood, etc. Fourier Transform based lock-in technique is used to detect the physiological signals reliably even when the signal is weak. In addition, ambient light can be used as the light source to complete the measurement. | 11-14-2013 |
Chun Zhang, Cary, NC US
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20130170340 | Dynamically Adjusting Active Members in Multichassis Link Bundle - In one embodiment, active links are added to, and removed from, a multichassis link bundle with one side of the multichassis link bundle terminated on multiple devices of a multichassis device. In one embodiment, adding active links includes selecting which particular device to which to add an active link to the multichassis link bundle based on a device priority of each of the multiple devices, with a device priority of a given device being based on a current number of active links associated with the given device. | 07-04-2013 |
Chun Zhang, Chongqip CN
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20140065123 | PEGYLATED ANALOGUE PROTEIN OR CANINE URATE OXIDASE, PREPARATION METHOD AND USE THEREOF - Provided are a PEGylated analogue protein of canine urate oxidase, preparation method and use thereof. The analogue protein of canine urate oxidase is a canine urate oxidase, or a chimeric protein comprising part of the amino acid sequence of a canine urate oxidase and part of the amino acid sequence of a human urate oxidase, or a mutant protein thereof. The PEGylated analogue protein of canine urate oxidase and pharmaceutical compositions thereof according to the present invention can be used for the prevention and/or treatment of hyperuricemia and chronic gout. | 03-06-2014 |
Chun Zhang, Zhengzhou CN
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20140038123 | DENTAL DRILL HEAD - A dental drill head, constituted of a head housing, a wind wheel, and bearings, the head housing being constituted of a head housing cover and a head housing cavity, and the wind wheel being constituted of a wind wheel shaft and wind wheel blades. An anti-suck-back device is configured between the head housing cover and a wind wheel shaft end part to which the wind wheel shaft corresponds. The present invention, which adopts the aforementioned technical scheme, firstly makes it possible to reduce the intake in of contaminants when suck-back is taking place as the impeller is braked; and secondly, while there is still a positive pressure inside the head, the rubber head covering uses elastic force to brake the impeller and completely prevents the intake of contaminants. Moreover, the structure is simple and costs are low. | 02-06-2014 |
Chun Zhang, Lexington, MA US
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20140004097 | METHOD OF PRODUCING RECOMBINANT IDURONATE-2-SULFATASE | 01-02-2014 |
Chun Zhang, Marietta, GA US
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20130264521 | Composite Materials and Method for Making High-Performance Carbon Nanotube Reinforced Polymer Composites - Nanocomposite materials and methods of making composite materials reinforced with carbon nanotubes are disclosed. The composite material includes an array of functionalized and aligned carbon nanotubes having a degree of functionalization of about 1% to about 10%; and a polymeric matrix material bonded to the array of functionalized and aligned carbon nanotubes. | 10-10-2013 |
20130274896 | PROSTHETIC SOCKET APPARATUS AND SYSTEMS - A prosthetic sock for a patient to wear over a residual limb is provided. The prosthetic sock includes an inner layer configured to fit over at least a portion of the residual limb of the patient. A foam layer is disposed on an outer surface of the inner layer. The foam layer compensates for changes in shape or volume of the residual limb within the prosthetic sock by changing shape in a manner effective to maintain a secure fit between the residual limb and a prosthetic socket of a prosthetic limb. | 10-17-2013 |
Chun Zhang, New Territories HK
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20140293279 | Raman Signal Detection and Analysing System and a Method Thereof - A Raman signal detection and analyzing system and a method thereof are disclosed. The Raman signal is generated by emitting an excitation light to a sample. The Raman signal is then modulated by passing through a plurality of optical filter and modulator. The resulting modulated Raman signal comprises two orthogonal components, which intensities are to be computed based on the first harmonic of said modulated Raman signal. The content of a specific analyte within the sample can then be determined based on the ratio of the intensities of the two components. | 10-02-2014 |
Chun Zhang, Beijing CN
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20150107982 | APPARATUS AND METHOD FOR PYROLYZING COAL WITH WIDE PARTICLE SIZE DISTRIBUTION - A carbonization apparatus for coal with wide particle size distribution, a carbonization apparatus unit, and a carbonization method based on the apparatus. The apparatus comprises a char discharge outlet ( | 04-23-2015 |
Chun Zhang, Palo Alto, CA US
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20160030561 | Methods of Treating Pancreatic Cancer - Novel methods of treating pancreatic cancer are provided. In one embodiment, the method comprises determining NOTCH mRNA expression levels in pancreatic cancer cells. In another embodiment, the method further comprises administering to a subject in need thereof a therapeutically effective dose of a NOTCH antagonist. | 02-04-2016 |
Chun Zhang, Nanjing, Jiangsu CN
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20160137557 | Method for Preparing Multichannel Ceramic Hollow Fiber Membrane - The Invention relates to a method for preparing a multichannel hollow fiber membrane. According to a certain ratio, ceramic powder, a macromolecular polymer, an organic solvent, and a dispersant are mixed evenly to prepare a membrane casting solution; and after bubble removing processing is performed on the membrane casting solution, a membrane green body is formed with the cooperation of a multichannel hollow fiber die and phase inversion. After the membrane green body is roasted at a high temperature, a multichannel ceramic hollow fiber membrane is formed. The multichannel ceramic hollow fiber membrane has an asymmetric structure and a skeleton structure in an inner cavity and can meet the strength and flux requirements of a ceramic hollow fiber membrane. | 05-19-2016 |