Patent application number | Description | Published |
20080286238 | Recombinant Adenovirus Expressing A Gene Encoding Streptolysin O Proetin and Anti-Cancer Composition Comprising Same - A recombinant adenovirus expressing a streptolysin O (SLO) protein comprising a SLO gene; a promoter operably linked to the SLO gene; a polyadenylation signal sequence; and an adenovirus genome lacking E1 gene effectively kills a cancer cell by expressing a pore-forming toxin, SLO protein, and, therefore, is useful for the suicide cancer gene therapy. | 11-20-2008 |
20090189652 | Frequency Multiplier - A frequency multiplier is disclosed. A plurality of voltage regulators each regulate levels of voltages at first and second common nodes in response to a corresponding one of input signals from a voltage-controlled delay line. An input buffer charges the first node or discharges the second node in response to a feedback signal. An output buffer regulates a level of a voltage at an output node and outputs a frequency-multiplied clock signal and the feedback signal corresponding to the voltage level of the output node. A discharge circuit discharges the first node before a rising edge of each of the input signals from the voltage-controlled delay line is inputted. A charge circuit charges the second node before the rising edge of each of the input signals from the voltage-controlled delay line is inputted. | 07-30-2009 |
20090202623 | GENE THERAPY FOR CANCER USING SMALL INTERFERING RNA SPECIFIC TO ANT2 AND A METHOD TO OVERCOME TOLERANCE TO ANTITUMOR AGENT - The present invention relates to a small interfering RNA (siRNA) suppressing the expression of adenine nucleotide trnaslocator 2 (ANT2) gene and an anticancer agent containing the same. Particularly, the invention relates to ANT2 siRNA comprising a sense sequence selected from the nucleotide sequences of ANT2 mRNA, a hairpin loop sequence and an antisense sequence binding complementarily to the said sense sequence and an anticancer agent containing the same. ANT2 siRNA of the present invention inhibits the expression of ANT2 gene, suggesting that it inhibits the growth of cancer cells exhibiting high level of ANT2. Therefore, ANT2 siRNA of the invention can be effectively used for gene therapy for cancer treatment and further prevents the anticancer effect from decreasing by anticancer drug resistance of cancer cells. | 08-13-2009 |
20100222263 | ATAP PEPTIDES, NUCLEIC ACIDS ENCODING THE SAME AND ASSOCIATED METHODS OF USE - Disclosed herein are nucleic acid sequences that encode pro-apoptotic polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of proliferative disorders and bacterial infections using the nucleic acids and proteins of the invention. | 09-02-2010 |
20100244914 | CLOCK GENERATOR TO REDUCE LONG TERM JITTER - A clock generator includes a controller, a digital phase locked loop (PLL) circuit, a charge pump phase locked loop (PLL) circuit and a divider. The controller generates a division factor and a first internal clock signal in response to a low-frequency reference clock signal and a multiplication factor. The digital PLL circuit generates a second internal clock signal in response to the reference clock signal, the division factor and the first internal clock signal. The charge pump PLL circuit generates a plurality of third internal clock signals by using the second internal clock signal. The divider generates a high-frequency clock signal in response to a phase selection signal, the division factor and the third internal clock signals. | 09-30-2010 |
20110102219 | SUCCESSIVE APPROXIMATION ANALOG/DIGITAL CONVERTER AND TIME-INTERLEAVED SUCCESSIVE APPROXIMATION ANALOG/DIGITAL CONVERTER - A successive approximation analog/digital converter includes a sample & hold part sampling and holding an intensity of an analog input signal using a single clock cycle of a clock signal; a first comparator comparing the intensity of the analog input signal with comparison voltages determined according to estimated digital values per clock cycle following an operating clock cycle of the sample & hold part; a second comparator comparing the intensity of the analog input signal with a value equal to ½ of a preset reference voltage in the latter half of the operating clock cycle of the sample & hold part; a successive approximation register determining a value of an MSB of a digital value to be converted according to the comparison result of the second comparator and values of bits successive to the MSB according to the comparison result of the first comparator, and generating the estimated digital values by applying estimated values to undetermined bits; and a digital/analog converter generating the comparison voltages using the estimated digital values and the reference voltage. | 05-05-2011 |
20110207798 | METHOD FOR TREATING BREAST CANCER USING ADENINE NUCLEOTIDE TRANSLOCATOR 2 (ANT2) SIRNA OR ANT2 SHRNA - The present invention relates to adenine nucleotide translocator 2 (ANT2) siRNA (small interfering RNA) or ANT2 shRNA (short hairpin RNA) suppressing the expression of ANT2 gene expression and anticancer agent containing the same. Furthermore, the present invention relates to methods for treating breast cancers or stem cells of a breast cancer by treating the same with ANT2 siRNA or ANT2 shRNA. In addition, the invention provides a method for inhibiting metastasis of breast cancer cells with ANT2 siRNA or ANT2 shRNA. | 08-25-2011 |
20110216864 | VARIABLE DELAY CIRCUIT AND DELAY-LOCKED LOOP INCLUDING THE SAME - The present disclosure provides a variable delay circuit comprising a delay circuit that includes a first delay unit and a second delay unit and delays an input signal to generate an output signal; a selection signal generation unit that detects a delay value of the delay circuit and generates a selection signal to select a delay unit for delaying the input signal from the first delay unit and the second delay unit; a first control unit that controls a delay value of the delay unit selected by the selection signal in response to a delay increase/decrease signal; and a second control unit that controls a delay value of the delay unit which is not selected by the selection signal. | 09-08-2011 |
20110228887 | LINEAR PHASE DETECTOR AND CLOCK/DATA RECOVERY CIRCUIT THEREOF - A linear phase detector includes an up/down pulse generator operating in response to received data signals and a recovered clock signal. The phase detector generates up and down pulses that have pulse widths proportional to the phase differences between transitions of the received data signals and edges of the recovered clock signal. By generating up and down pulses using a linear phase detector in proportion to a phase error, data signals are effectively recovered, even data signals with significant jitter. | 09-22-2011 |
20120001658 | MODULATION PROFILE GENERATOR AND SPREAD SPECTRUM CLOCK GENERATOR INCLUDING THE SAME - There is provided a modulation profile generator and spread spectrum clock generator including the modulation profile generator. The modulation profile generator includes an input signal generator that generates an input signal; a function calculator that outputs a function calculation result in the form of a square root graph by using the input signal as an input of a function; and a profile generator that generates a non-linear modulation profile based on the function calculation result. As a result, it is possible to effectively reduce electromagnetic interference. | 01-05-2012 |
20130135038 | SEMICONDUCTOR APPARATUS - A semiconductor apparatus includes a power supply changing unit. The power supply changing unit is configured to receive an enable signal and power supply voltage, generate first voltage or second voltage according to the enable signal, change a voltage level of the second voltage according to a level signal, and supply the first voltage or the second voltage as a driving voltage of an internal circuit, wherein the internal circuit receives a first input signal to output a second input signal. | 05-30-2013 |
20130147457 | SINGLE INDUCTOR MULTIPLE OUTPUT (SIMO) DIRECT CURRENT-TO-DIRECT CURRENT (DC/DC) CONVERTER AND CONTROL METHOD THEREOF - Provided is a single inductor multiple output (SIMO) direct current-to-direct current (DC/DC) converter that may perform DC/DC conversion by transferring, to output nodes, input current that is input and thereby stored in a single inductor. An output selection unit of the SIMO DC/DC converter may select, from output nodes, a first output node to be supplied with current from a driving unit, and provide output voltage of the first output node and reference voltage of the first output node to a hysteresis comparison unit. The hysteresis comparison unit may control on-time and/or inductor peak current by determining whether the output voltage of the first output node is higher than the reference voltage of the first output node by at least a first threshold, and whether the output voltage of the first output voltage is lower than the reference voltage of the first output voltage by at least a second threshold. | 06-13-2013 |
20130162335 | CHARGE PUMPING APPARATUS USING OPTIMUM POWER POINT TRACKING AND METHOD THEREOF - A charge pumping apparatus includes a voltage pumping unit for pumping an input voltage, a voltage pumping control unit for controlling the voltage pumping unit according to a comparison result between the input voltage and an input criterion voltage and a comparison result between an output voltage output from the voltage pumping unit and an output criterion voltage, and an optimum power point tracking unit for tracking an optimum power point in the case of detecting that the output voltage decreases lower than the output criterion voltage, and adjusting an input impedance to change the input criterion voltage to a voltage corresponding to the optimum power point, wherein the optimum power point is a power point where an input power according to the input voltage becomes a maximum. Since the optimum power point is tracked by measuring only a voltage without a current sensor, a power loss is small. | 06-27-2013 |
20130332395 | SYSTEM AND METHOD FOR MANAGING CONTENTS PRICE - A contents price managing method includes providing contents information including a contents price to a first device; if contents corresponding to the provided contents information is output using the first device, calculating a contents usage fee for the first device based on the contents price and an output length of the contents that is output through the first device. The method may further include updating the contents price based on the output length of the contents; and providing contents information including the updated contents price to a second device. | 12-12-2013 |
Patent application number | Description | Published |
20110095603 | EMERGENCY CONTROL APPARATUS AND METHOD FOR USE - The present invention provides an emergency control apparatus, and method which maintains the power flow between a battery and an inverter and the operation state of an electric vehicle in the event of failure of a bidirectional DC-DC converter connected between the battery as a power source and the inverter for operating a drive motor. | 04-28-2011 |
20110106469 | CIRCUIT AND METHOD FOR DETECTING SHORT AND DISCONNECTION OF RESOLVER FOR HYBRID ELECTRIC VEHICLE - The present invention relates to a circuit and method for detecting a short and a disconnection of a resolver for a Hybrid Electric Vehicle (HEV), which can accurately analyze and detect the fault code of the resolver which detects the speed of a drive motor for an HEV and the angle of a rotator for an HEV. | 05-05-2011 |
20110134959 | METHOD FOR MEASURING TEMPERATURE OF MOTOR FOR HYBRID ELECTRIC VEHICLE - The present invention provides a method for measuring the temperature of a motor for a hybrid electric vehicle. In preferred embodiments, the method of the present invention can preferably ensure the stability and reliability of motor control by extending the linearity of a temperature sensor attached to the motor within a required measurement range. | 06-09-2011 |
20130278126 | REFRIGERATOR - A refrigerator having an improved structure of a storage box and a shelf thereof so as to achieve increased space utilization of a storage compartment. The storage box may have slide protrusions respectively formed on both of outer side-faces of the storage box at a lower portion thereof to allow the storage box to be slidably retracted in or extended from the storage compartment. The shelf may have a support structure to support food thereon and slide grooves respectively formed above both sides of the support structure, each groove receiving the corresponding slide protrusion of the storage box. When the storage box is mounted on the shelf, food may be put in the inner space of the storage box, whereas when the storage box is dismounted from the shelf, a food storage space may be present on the support structure of the shelf. | 10-24-2013 |