Patent application number | Description | Published |
20110039944 | VOLATILE ANESTHETIC COMPOSITIONS COMPRISING EXTRACTIVE SOLVENTS FOR REGIONAL ANESTHESIA AND/OR PAIN RELIEF - The present invention provides methods for reducing pain in a subject in need of such pain reduction by delivering, e.g., intrathecally or epidurally, a volatile anesthetic dissolved in a solution comprising an extractive solvent, e.g., DMSO or NMP, in an amount effective to reduce pain. Chronic or acute pain may be treated, or the anesthetic may be delivered as a regional anesthesia to a subject to anesthetize a portion the subject prior to a surgery, hi certain embodiments, isoflurane, halothane, enflurane, sevoflurane, desflurane, methoxyflurane, or mixtures thereof may be used. Dosing regimens including a one-time administration, continuous and/or periodic administration are contemplated. | 02-17-2011 |
20110060603 | Population Adjusted Indexes - Articles of manufacture including electronic machines including but not limited to computers, computer stations, computing devices, computer systems, software, computer readable memory and other electronic devices adapted to provide an index for a performance characteristic or measure for groups of people or institutions. The index values are risk adjusted to the varying population compositions for groups of people or institutions by comparison to a reference portfolio and are updated in real time to account for the changing constitution of the clusters in the portfolios. Methods of using the disclosed devices include the ability to provide a continuously updated benchmark for the comparison of medical, business or educational performance by providers or practitioners of such services that effect populations of individuals, and that is based on measurable outcomes. Additionally, the methods of using the disclosed devices include the ability to compare the effectiveness of different therapies. | 03-10-2011 |
20130018287 | APPARATUS FOR GENERATING THERAPEUTIC SHOCKWAVES AND APPLICATIONS OF SAME - Apparatuses and methods to generate high frequency shock waves in a controlled manner. The generated shock waves can be delivered to certain cellular structures of a patient for use in medical and/or aesthetic therapeutic applications. The shock waves can be configured to impose sufficient mechanical stress to the targeted cells of the tissue to rupture the targeted cells. Embodiments of the apparatuses and methods of the present invention provide targeted rupturing of specific cells without damaging side effects such as cavitation or thermal degradation of surrounding non-targeted cells. | 01-17-2013 |
20130046207 | APPARATUSES AND SYSTEMS FOR GENERATING HIGH-FREQUENCY SHOCKWAVES, AND METHODS OF USE - Apparatuses and methods for generating therapeutic shock waves. Some embodiments comprise: an acoustic-wave generator configured to emit acoustic waves having at least one frequency between 1 MHz and 1000 MHz; a shock wave housing coupled to the acoustic-wave generator; and a shock wave medium disposed in the shock wave housing; where the apparatus is configured such that if the acoustic-wave generator emits acoustic waves then at least some portion of the acoustic waves will travel through the shock wave medium and form one or more shock waves. | 02-21-2013 |
20130085467 | ROBOTIC INFUSION MIXER AND TRANSPORTABLE CARTRIDGE - The invention relates to a transportable therapeutic cartridge, a therapeutic agent robotic mixer and a method for providing therapeutic infusion services. The transportable therapeutic cartridge is configured to be used to manually mix therapeutic agents or to be coupled to a therapeutic agent robotic mixer, such that the robotic mixer can access therapeutic agents disposed in the cartridge. The cartridge, mixer, and method provide therapeutic infusions in a just-in-time fashion, so as to minimize risk to patients and facility staff while maximizing the use and safety of the therapeutics. | 04-04-2013 |
20130273141 | VOLATILE ANESTHETIC COMPOSITIONS AND METHODS OF USE - The present invention provides methods for reducing pain in a subject in need thereof by delivering a volatile anesthetic in a solution or an emulsion that can additionally include an extractive solvent in an amount effective to reduce pain without substantially interfering with motor function. Chronic or acute pain may be treated, or the volatile anesthetic may be delivered as a regional anesthetic to a subject to anesthetize a portion of the subject prior to surgery. Dosing regimes including a one-time administration, continuous and/or periodic administration are contemplated. | 10-17-2013 |
20140257144 | Rapid Pulse Electrohydraulic (EH) Shockwave Generator Apparatus and Methods for Medical and Cosmetic Treatments - Apparatuses and methods for electrohydraulic generation of shockwaves at a rate of between 10 Hz and 5 MHz, and/or that permit a user to view a region of a patient comprising target cells during application of generated shockwaves to the region. Methods of applying electro-hydraulically generated shockwaves to target tissues (e.g., for reducing the appearance of tattoos, treatment or reduction of certain conditions and/or maladies). | 09-11-2014 |
20150017220 | Rapid Preparation of Stem Cell Matrices for Use in Tissue and Organ Treatment and Repair - A rapid method for preparing stem cell and physiologically acceptable matrix compositions for use in tissue and organ repair is described. Compared with previous tissue engineering materials, the stem cell-matrix compositions of the present invention do not require long-term incubation or cultivation in vitro prior to use in in vivo applications. The stem cells can be from numerous sources and may be homogeneous, heterogeneous, autologous, and/or allogeneic in the matrix material. The stem cell-matrix compositions provide point of service utility for the practitioner, wherein the stem cells and matrix can be combined not long before use, thereby alleviating costly and lengthy manufacturing procedures. In addition, the stem cells offer unique structural properties to the matrix composition which improves outcome and healing after use. Use of stem cells obtained from muscle affords contractility to the matrix composition. | 01-15-2015 |
20150071887 | Soft Tissue and Bone Augmentation and Bulking Utilizing Muscle-Derived Progenitor Cells, Compositions and Treatments Thereof - The present invention provides muscle-derived progenitor cells that show long-term survival following transplantation into body tissues and which can augment soft tissue following introduction (e.g. via injection, transplantation, or implantation) into a site of soft tissue. Also provided are methods of isolating muscle-derived progenitor cells, and methods of genetically modifying the cells for gene transfer therapy. The invention further provides methods of using compositions comprising muscle-derived progenitor cells for the augmentation and bulking of mammalian, including human, soft tissues in the treatment of various cosmetic or functional conditions, including malformation, injury, weakness, disease, or dysfunction. In particular, the present invention provides treatments and amelioration for dermatological conditions, gastroesophageal reflux, vesico-ureteral reflux, urinary incontinence, fecal incontinence, heart failure, and myocardial infarction. | 03-12-2015 |