Patent application number | Description | Published |
20110124055 | Methods for High Fidelity Production of Long Nucleic Acid Molecules - In a method for synthesizing a long nucleic acid molecule, a first immobilized nucleic acid has a first 5′ region and a first 3′ region and a second immobilized nucleic acid has a second 5′ region and a second 3′ region, wherein the second 3′ region and the first 5′ region have identical nucleic acid sequences. The first immobilized nucleic acid is hybridized with an oligonucleotide under conditions promoting hybridization of the oligonucleotide to the first 3′ region, extending the hybridized oligonucleotide and producing a first extension product having a 3′ region that is complementary to the first 5′ region. The second immobilized nucleic acid is hybridized with the first extension product under conditions promoting hybridization of the 3′ region of the first extension product to the second 3′ region, extending the 3′ region of the first extension product and producing a second extension product having a 3′ region that is complementary to the second 5′ region, wherein the second extension product has a sequence complementary to the first and second 3′ and 5′ regions. | 05-26-2011 |
20110165681 | Light-Activated Proton Pumps and Applications Thereof - In a method for adjusting the voltage potential or pH of, or cause proton release from, cells, subcellular regions, or extracellular regions, a gene encoding for a light-driven proton pump is incorporated into at least one target cell or region, the proton pump operating in response to a specific wavelength of light. Expression of the gene is caused by exposing the target cell or region to the specific wavelength of light in a manner designed to cause the voltage potential adjustment, pH adjustment, or proton release. The proton pump may be a microbial rhodopsin, in particular derived from the | 07-07-2011 |
20110201057 | Methods for High Fidelity Production of Long Nucleic Acid Molecules with Error Control - A method for synthesizing a nucleic acid having a desired sequence and length comprises providing a solid support having an immobilized nucleic acid, performing a nucleic acid addition reaction to elongate the immobilized nucleic acid by adding a nucleotide or an oligonucleotide to the nucleic acid, determining whether the nucleotide or the oligonucleotide is added to the nucleic acid by detecting whether there is an increase in electrophoretic force applied to the solid support when an electric field and a magnetic field gradient are applied to the support, wherein the increase in electrophoretic force applied to the support is caused by adding the nucleotide or the oligonucleotide to the nucleic acid, repeating the addition reaction and determination steps if the nucleotide or the oligonucleotide is not added to the nucleic acid, and continuing until the immobilized nucleic acid has a desired sequence and length. | 08-18-2011 |
20120264653 | Methods for High Fidelity Production of Long Nucleic Acid Molecules - In a method for synthesizing a pool of nucleic acid molecules, a first nucleic acid has a first 5′ region and a first 3′ region and a second nucleic acid has a second 5′ region and a second 3′ region. The second 3′ region and the first 5′ region have identical nucleic acid sequences. The first 3′ region is hybridized with an oligonucleotide, extending the hybridized oligonucleotide and producing a first extension product having a 3′ region complementary to the first 5′ region. The second nucleic acid is hybridized with the first extension product to hybridize the 3′ region of the first extension product to the second 3′ region, extending the 3′ region of the first extension product and producing a second extension product having a 3′ region complementary to the second 5′ region. Error-containing molecules are separated from error-free molecules by a component that selects for a sequence error. | 10-18-2012 |
20130005612 | Methods for High Fidelity Production of Long Nucleic Acid Molecules with Error Control - A method for synthesizing a nucleic acid having a desired sequence and length comprises providing a solid support having an immobilized nucleic acid, performing a nucleic acid addition reaction to elongate the immobilized nucleic acid by adding a nucleotide or an oligonucleotide attached to a protecting group to the nucleic acid, determining whether the nucleotide or the oligonucleotide is added to the nucleic acid, removing the protecting group, and continuing until the immobilized nucleic acid has a desired sequence and length. | 01-03-2013 |
20130098771 | Photoelectrochemical Synthesis of High Density Combinatorial Polymer Arrays - In a method for creating polymer arrays through photoelectrochemically modulated acid/base/radical generation for combinatorial synthesis, electrochemical synthesis is guided by a spatially modulated light source striking a semiconductor in an electrolyte solution. A substrate having at its surface at least one photoelectrode that is proximate to at least one molecule bearing at least one chemical functional group is provided, along with a reagent-generating chemistry co-localized with the chemical functional group and capable of generating reagents when subjected to a potential above a threshold. An input potential is then applied to the photoelectrode that exceeds the threshold in the presence of light and that does not exceed the threshold in the absence of light, causing the transfer of electrons to or from the substrate, and creating a patterned substrate. The process is repeated until a polymer array of desired size is created. | 04-25-2013 |
20130323722 | Methods for High Fidelity Production of Long Nucleic Acid Molecules - In a method for generating a long nucleic acid molecule, nucleic acids immobilized on a surface and having overlapping complementary sequences is released into solution. The overlapping complementary sequences are hybridized to form hybridized nucleic acids, followed by extension or ligation of the hybridized nucleic acids to synthesize the long nucleic acid molecule. The nucleic acids may comprise first and second series of nucleic acids having redundant overlapping sequences, wherein nucleic acids from the first and second series are complementary to each other. The complementary nucleic acids are hybridized to form the hybridized nucleic acids. The generated long nucleic acid molecule may have a predetermined sequence element, and it may be introduced into a system wherein the predetermined sequence element is required for replication, such that replication of the synthesized long nucleic acid molecule is indicative of the presence of the predetermined sequence element in the long nucleic acid molecule. | 12-05-2013 |
Patent application number | Description | Published |
20110143464 | Methods and Apparatus for Control of Hydrothermal Nanowire Synthesis - In exemplary implementations of this invention, hydrothermal synthesis of zinc oxide nanowires is morphologically controlled. Metal complex ions are used to suppress growth in a face-selective manner, by electrostatic crystal growth inhibition. This permits the aspect ratio (height/diameter) of the nanowires to be dynamically tuned over a wide range, from needle-like nanowires that are efficient field emitters to flattened nanowires with a platelet-like shape. The nanowire synthesis is all inorganic and occurs at low temperatures (e.g., <=60° C.). The growth inhibition may be predictively modeled, using speciation plots and treating non-zinc complex ions as ligands. Microfluidic channels may be used for the synthesis, with different solutions flowing down different channels, permitting nanowires with different properties to be synthesized in parallel. This invention may be used to produce field emission devices and nanowire-embedded AC electroluminescent devices, and for in-situ fabrication of spatially complex integrated devices in a polymeric microfluidic system. | 06-16-2011 |
20120121542 | RED-SHIFTED OPSIN MOLECULES AND USES THEREOF - The invention, in some aspects relates to compositions and methods for altering cell activity and function and the use of light-activated ion pumps (LAIPs). | 05-17-2012 |
20120214188 | LIGHT-ACTIVATED ION CHANNEL MOLECULES AND USES THEREOF - The invention, in some aspects relates to compositions and methods for altering cell activity and function and the use of light-activated ion channels (LAICs). | 08-23-2012 |
20130225963 | Automated Cell Patch Clamping Method and Apparatus - In an automated methodology for carrying out in vivo cell patch clamping, a cell patch clamping device is automatically moved into position and targeted to a neuron. Neuron contact is determined by analyzing the temporal series of measured resistance levels at the cell patch clamping device as it is moved. The difference between successive resistance levels is computed and compared to a threshold, which must be exceeded for a minimum number of computations before neuron contact is assumed. Pneumatic control methods are used to achieve gigaseal formation and cell break-in, leading to whole-cell patch clamp formation. An automated robotic system capable of performing this methodology automatically performs patch clamping in vivo, automatically detecting cells by analyzing the temporal sequence of electrode impedance changes. By continuously monitoring the patching process and rapidly executing actions triggered by specific measurements, the robot can rapidly find neurons in the living brain and establish recordings. | 08-29-2013 |
20140324134 | CHANNELRHODOPSINS FOR OPTICAL CONTROL OF CELLS - The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of light-activated ion channels. | 10-30-2014 |
Patent application number | Description | Published |
20120306887 | MULTIPLE ELEMENT SELECTIONS IN GANTT CHARTS - Various arrangements for manipulating multiple elements of a Gantt chart are presented. The Gantt chart may be generated comprising a plurality of elements distributed across a plurality of groups. A selection of a subset of elements from the plurality of elements may be received, wherein the subset of elements of the Gantt chart comprises elements from at least a first group and a second group of the plurality of groups of the Gantt chart. An application programming interface may be executed to retrieve an element identifier for each element of the subset of elements of the Gantt chart, wherein each element identifier corresponds to only one element of the Gantt chart. | 12-06-2012 |
20130086501 | VISUALIZING RELATED EVENTS WITHIN A TIMELINE - A timeline visualization system displays one or more groups of related events over a specified period of time within a timeline, where each group of related events is represented within the timeline as an event group. When a user interacts with the timeline, the event group expands and displays all the related events within the event group in a layer on top of the timeline. When a user interacts with the timeline a second time, the event group collapses, and the timeline (including the one or more event groups), is once again displayed. | 04-04-2013 |
20130104021 | ADAPTIVE NAVIGATION FUNCTIONALITY IN A WEB-BASED DATA-ENTRY GRID - Techniques for facilitating navigation in a web-based data entry grid. In one set of embodiments, when a user navigates into a cell of the data entry grid, the user's web browser can wait for a predetermined time period before accessing an application server to retrieve input control information for the cell. If the user enters a command to navigate away from the cell before the predetermined time period has passed, the server access can be avoided, and thus the navigation event can be processed immediately. If no navigation command is received from the user before the predetermined time period has passed, the input control information can be retrieved from the application server and rendered. | 04-25-2013 |
20130227412 | TOOLTIP FEEDBACK FOR ZOOM USING SCROLL WHEEL - Tooltip generation for zoom feedback is described. In response to the initiation of a zoom operation, a tooltip is generated. The tooltip shows an established potential zoom level that will be used to execute the zoom operation if no other zoom level is established or selected. Multiple potential zoom levels may be shown within the tooltip before the zoom operation is executed. | 08-29-2013 |
Patent application number | Description | Published |
20120134225 | SENSE AMPLIFIER LATCH WITH INTEGRATED TEST DATA MULTIPLEXER - A sense amplifier latch may be provided to controllably latch the output of a sense amplifier. The latch may open in response to assertion of a latch enable signal to receive data, and close in response to deassertion of the latch enable signal to capture and store the received data. Additionally, a multiplexer may be provided to select from among multiple sources of test data, such as scan data and bypass data. The multiplexer may produce a test data input to the sense amplifier latch that encodes a data value and a control value that causes the data value to be selected. Depending on the state of the test data input, the sense amplifier latch may output either a value received from the sense amplifier or a value encoded in the test data input. | 05-31-2012 |
20120134226 | SENSE AMPLIFIER AND SENSE AMPLIFIER LATCH HAVING COMMON CONTROL - A sense amplifier of a memory array may be provided to amplify data presented from storage cells of the memory array. Additionally, a sense amplifier latch may be provided to store data received from the sense amplifier. The sense amplifier may be enabled for operation by a sense amplifier enable signal that is distinct from a clock signal. Moreover, the latch enable signal of the sense amplifier latch may be controlled by the sense amplifier enable signal, such that the sense amplifier latch opens in response to activation of the sense amplifier and closes in response to deactivation of the sense amplifier. | 05-31-2012 |
20130111130 | MEMORY INCLUDING A REDUCED LEAKAGE WORDLINE DRIVER | 05-02-2013 |
20130141988 | MEMORY WITH A SHARED I/O INCLUDING AN OUTPUT DATA LATCH HAVING AN INTEGRATED CLAMP - A memory includes a shared I/O unit that is shared between multiple storage arrays provides output data from the arrays. The shared I/O includes an output latch with an integrated output clamp. The I/O unit may be configured to provide output data from the storage arrays via data output signal paths. The I/O unit includes an output latch configured to force a valid logic level on the data output signal paths in response to a power down condition. | 06-06-2013 |
20130188435 | MEMORY HAVING ISOLATION UNITS FOR ISOLATING STORAGE ARRAYS FROM A SHARED I/O DURING RETENTION MODE OPERATION - A memory includes an I/O unit that is shared between multiple storage arrays. The shared I/O unit provides output data from the arrays. The memory includes an isolation unit connected between each storage array and the shared I/O unit. In addition, each of the storage arrays and the shared I/O unit may be connected to a separate switched voltage domain through for example, power gating circuits. If one or more of the storage arrays is placed in retention or low-voltage mode, the isolation units that are coupled to the affected storage arrays may be configured to isolate the bitlines of those storage arrays from the shared I/O data paths. | 07-25-2013 |
20140016392 | Memory Having Isolation Units For Isolating Storage Arrays From A Shared I/O During Retention Mode Operation - A memory includes an I/O unit that is shared between multiple storage arrays. The shared I/O unit provides output data from the arrays. The memory includes an isolation unit connected between each storage array and the shared I/O unit. In addition, each of the storage arrays and the shared I/O unit may be connected to a separate switched voltage domain through for example, power gating circuits. If one or more of the storage arrays is placed in retention or low-voltage mode, the isolation units that are coupled to the affected storage arrays may be configured to isolate the bitlines of those storage arrays from the shared I/O data paths. | 01-16-2014 |
20140219009 | LOW VOLTAGE BOOTSTRAPPING METHOD FOR WRITE ASSIST - Embodiments of a memory are disclosed that may allow for a negative boost of data lines during a write. The memory device may include a data input circuit, an address decode circuit and a plurality of sub-arrays. Each of the sub-arrays may include a plurality of columns, a write selection circuit, a first write driver circuit, a second write driver circuit, and a boost circuit. Each of the columns may include a plurality of data storage cells. The write selection circuit may select a column of the plurality of columns. Each of the write driver circuits may configured to discharge a data line of a selected column into a common node. The boost circuit may be configured to initialize the common node to the first voltage level and couple the common node to a second voltage level, where the second voltage level is lower than the first voltage level. | 08-07-2014 |
Patent application number | Description | Published |
20090306715 | INTERSPINOUS PROCESS SPACER - An interspinous process spacer is generally rectangular and may have an upper face that generally opposes a lower face, front and back sides that generally oppose each other, an end side, and a nose that generally opposes the end side. The spacer preferably has rounded edges between the upper face and the front, end, and back sides and between the lower face and the front, end, and back sides. The nose of the spacer is preferably asymmetrical and tapers integrally, distally, and inwardly from the first and second faces to form a generally pointed or rounded distal tip. A spacer may be inserted laterally into the interspinous space through a small, posterior midline incision, allowing the preservation of the supraspinous ligament. One or more spacers may be placed between spinous processes of adjacent vertebrae, and result in distraction of the spinous processes which may limit extension of the spine. Implantation of an interspinous process may inhibit or prevent the narrowing of the spinal canal and neural foramen at the level of treatment, thereby relieving pain symptoms. Preservation of the supraspinous ligament may provide additional stability, for example by keeping the implant from migrating posteriorly. | 12-10-2009 |
20100280620 | TRIAL IMPLANT ASSEMBLY - A trial implant assembly is provided that includes a threaded shaft having exterior threading adjacent a distal end and a trial implant that includes a trial base having an interiorly threaded through hole couplable to the distal end of the shaft and a trial head having a superior endplate and an inferior endplate and a support connecting the superior endplate to the inferior endplate. A variety of visualization windows are provided through the trial implant as well as a variety of mechanically adjustable stops to prevent over insertion of the trial head within the intervertebral disc space. | 11-04-2010 |
20110046679 | BONE FASTENERS AND METHOD FOR STABILIZING VERTEBRAL BONE FACETS USING THE BONE FASTENERS - A bone fastener for stabilizing bone fragments includes a single or multiple components coupleable with one another and displaceable to a locked position of the bone fastener. | 02-24-2011 |
20110082504 | INFLATABLE INTERSPINOUS SPACER - The present invention is directed to an inflated interspinous spacer. The interspinous spacer is inserted into the interspinous space between adjacent spinous process in a deflated or unexpanded state, and is inflated or expanded with an injectable filler material. Upon inflation, the spacer preferably distracts the spinous processes and assumes a shape that retains the spacer in position and preferably mechanically locks with the spinous processes. The spacer includes two separate balloons configured to have different compressive modulus so that one balloon is softer and more deformable than the other balloon. | 04-07-2011 |
20110160773 | BONE-DERIVED SPACER ASSEMBLY - An allograft interspinous spacer for implantation into an interspinous space located between spinous process of adjacent vertebrae. The spacer preferably includes a body, a core and a plurality of deployable retainers. The body may be operatively associated with the plurality of deployable retainers. In use, after the body has been inserted into the interspinous space, the plurality of retainers is deployed so that they prevent migration of the spacer. The core is preferably sized and configured to be inserted and/or moved into operatively engagement with the body to deploy the plurality of retainers. | 06-30-2011 |
20120010659 | FACET FUSION IMPLANT - Facet fusion implants with various body geometries are provided. The bodies of the facet fusion implants can be configured to minimize migration of the implants when the implants are inserted into facet joints. Surgical methods and accompanying surgical instrumentation for inserting the facet fusion implants into facet joints are provided. | 01-12-2012 |
20140277144 | SPINOUS PROCESS FIXATOR - The present invention is directed to an interspinous spacer assembly for implantation and/or affixation between spinous processes of adjacent superior and inferior vertebrae and associated tools and methods for stabilizing the human spine. The interspinous spacer assembly includes a spacer body, a first lateral plate, a second lateral plate and a locking mechanism extending through a channel provided in the spacer body and coupling the first and second lateral plates to the spacer body. | 09-18-2014 |
Patent application number | Description | Published |
20080293796 | Parenteral and oral formulations of benzimidazoles - Provided herein are drug delivery systems comprising nanosuspension formulations suitable for parenteral delivery to a subject. The nanosuspension formulations may comprise a benzimidazole derivative, e.g., mebendazole, and surface stabilizers, such as block copolymer(s), e.g., Pluronic F108, and surfactant(s), e.g., Tween 80, and, optionally, water. Provided are methods for defining nanosuspensions of a benzimidazole derivative as having maximum therapeutic efficacy for a treatment regimen by adjusting and/or selecting particles size(s) based on pharmacokinetic parameters of the derivative in the tissue. Also provided are methods for improving the bioavailability of a benzimidazole derivative during treatment of a pathophysiological condition and for treating a cancer by using formulation(s) combining particle diameters whereby the retention of the benzimidazole derivative within the particles increases as the diameter increases such that, upon administration, release of the benzimidazole derivative from the particles into tissue is continuous over a range of time as determined by the particle diameters. | 11-27-2008 |
20090048322 | Parenteral and oral formulations of benzimidazoles - Provided herein are drug delivery systems, such as self-nanoemulsifying drug delivery systems, self-emulsifying drug delivery systems and parenteral microemulsion formulations, suitable for parenteral or oral delivery to a subject. The drug delivery systems may comprise a benzimidazole derivative, e.g., mebendazole, an oil, a surfactant, a cosurfactant and a dipolar aprotic solvent in a microemulsion formulation. Also provided are methods for improving the bioavailability of a benzimidazole derivative during treatment of a pathophysiological condition by using a formulation combining a particular emulsion droplet diameter and ratio of the surfactant:cosurfactant therein, for increasing concentration and retention of a benzimidazole derivative in the lung via a parenterally administerable microemulsion with droplet size of about 35 nm to less than 100 nm and for defining hemolytically safe microemulsions of a benzimidazole derivative during a therapeutic treatment via a parenterally administerable microemulsion with a surfactant:cosurfactant content by weight of about 6% to 48%. | 02-19-2009 |
20100310611 | Parenteral and oral formulations of benzimidazoles - Provided herein are drug delivery systems, such as self-nanoemulsifying drug delivery systems, self-emulsifying drug delivery systems and parenteral microemulsion formulations, suitable for parenteral or oral delivery to a subject. The drug delivery systems may comprise a benzimidazole derivative, e.g., mebendazole, an oil, a surfactant, a cosurfactant and a dipolar aprotic solvent in a microemulsion formulation. Also provided are methods for improving the bioavailability of a benzimidazole derivative during treatment of a pathophysiological condition by using a formulation combining a particular emulsion droplet diameter and ratio of the surfactant:cosurfactant therein, for increasing concentration and retention of a benzimidazole derivative in the lung via a parenterally administerable microemulsion with droplet size of about 35 nm to less than 100 nm and for defining hemolytically safe microemulsions of a benzimidazole derivative during a therapeutic treatment via a parenterally administerable microemulsion with a surfactant:cosurfactant content by weight of about 6% to 48%. | 12-09-2010 |
20110189288 | DIETHYLSTILBESTROL DOSAGE FORM AND METHODS OF TREATMENT - Oral dosage forms as a biodegradable, water soluble film for delivering pharmaceutically active agents, particularly diethylstilbestrol and pharmaceutically acceptable salts thereof to patients through insertion into the mouth of patient and methods for administering pharmaceutically active agents to patients by insertion into the mouth to provide selective uptake of said agents through the mucosa and thus avoiding the gastrointestinal tract. | 08-04-2011 |
Patent application number | Description | Published |
20120274271 | INDUCTIVELY RECHARGEABLE IMPLANTABLE DEVICE WITH REDUCED EDDY CURRENTS - A case for an implantable medical device includes a metal case portion, having an inside and an outside, configured to attach to at least one other case portion to define a biocompatible case for the implantable medical device. The metal case portion has a plurality of grooves disposed on at least one of the inside and the outside, the grooves being oriented substantially perpendicular to an expected direction of eddy currents produced by an inductive recharging coil in proximity thereto. | 11-01-2012 |
20120276854 | Slot Antenna For An Implantable Device - An implantable medical device may include a case which houses components of the implantable medical device. The implantable medical device may include an inductive coil coupled to a rechargeable battery. The inductive coil may be operative to inductively couple to an external coil and to transfer energy from the external coil to the rechargeable battery to recharge the rechargeable battery. The implantable medical device may include a cutout formed in the case of the implantable medical device and filled with a dielectric material. The cutout may be operative to reduce eddy currents in the case during recharge of the rechargeable battery. The implantable medical device may include a slot antenna disposed within the case. The slot antenna may be operative to communicate with an external device through the cutout in the case. | 11-01-2012 |
20120276856 | IMPLANTABLE MEDICAL DEVICE ANTENNA - An implantable medical device includes a case having a conductive housing defining an opening. A dielectric material is coupled to the conductive housing to hermetically seal the opening. An antenna is within the case under the dielectric material. A header block is coupled to the case over the dielectric material. | 11-01-2012 |
20120277829 | SYSTEM AND METHOD FOR CHARGING A POWER CELL IN AN IMPLANTABLE MEDICAL DEVICE - Apparatus and methods for charging a power cell in an implantable medical device (“IMD”) are disclosed herein. In one embodiment, a method includes providing an electrical pulse to an inductor external to the IMD. A frequency of an oscillation signal induced in the inductor by the current pulse is measured. The inductor is driven with an oscillating signal having a frequency based on the measured frequency of the oscillation signal. The power cell is charged using current induced in the IMD by the driving of the inductor. | 11-01-2012 |
20130018438 | FAR FIELD RADIATIVE POWERING OF IMPLANTABLE MEDICAL THERAPY DELIVERY DEVICES - A particular implantable device may include an antenna configured to receive a far field radiative signal. The implantable device may also include a voltage rectifier configured to rectify the far field radiative signal received by the antenna to provide a rectified voltage signal. The implantable device may further include a charge storage element operative to receive the rectified voltage signal and to store charge responsive to the rectified voltage signal. The implantable device may also include a therapy delivery unit powered by the charge storage element. The therapy delivery unit is operative to deliver a therapy to a patient. | 01-17-2013 |
20130018439 | IMPLANTABLE NERVE WRAP FOR NERVE STIMULATION CONFIGURED FOR FAR FIELD RADIATIVE POWERING - A particular implantable device may include an antenna configured to receive a far field radiative signal. The implantable device may also include a voltage rectifier configured to rectify the far field radiative signal received by the antenna to provide a rectified voltage signal. The implantable device may further include a charge storage element operative to receive the rectified voltage signal and to store charge responsive to the rectified voltage signal. The implantable device may also include a stimulation module powered by the charge storage element. The stimulation module may be operative to generate an electrical stimulation signal to stimulate a target nerve of a patient. The implantable medical device may further include a nerve wrap configured to house the voltage rectifier, the charge storage element, and the stimulation module. The nerve wrap may include one or more electrodes operative to deliver the electrical stimulation signal to the target nerve. | 01-17-2013 |
20130018440 | POWERING OF AN IMPLANTABLE MEDICAL THERAPY DELIVERY DEVICE USING FAR FIELD RADIATIVE POWERING AT MULTIPLE FREQUENCIES - A particular implantable device may include one or more antennas configured to receive a first far field radiative signal and a second far field radiative signal. The one or more antennas may be configured to receive the first far field radiative signal in a first frequency band and to receive the second far field radiative signal in a second frequency band. The implantable device may include a voltage rectifier configured to rectify the received first far field radiative signal and the received second far field radiative signal to provide a rectified voltage signal. The implantable device may further include a charge storage element operative to receive the rectified voltage signal and to store charge responsive to the rectified voltage signal. The implantable device may also include a therapy delivery unit powered by the charge storage element. The therapy delivery unit may be operative to deliver a therapy to a patient. | 01-17-2013 |
20130253612 | CIRCUIT, SYSTEM AND METHOD FOR FAR-FIELD RADIATIVE POWERING OF AN IMPLANTABLE MEDICAL DEVICE - An isolated circuit including a RF input configured to receive a far field radiative powering signal and a rectified voltage output configured to provide a rectified voltage based on the received far field radiative powering signal. The isolated circuit also includes a first power assembly comprising a first impedance coupled to the RF input where the first impedance is provided, at least in part, by activating a first switch in response to the rectified voltage satisfying a first voltage threshold. The isolated circuit also includes a second power assembly comprising a second impedance coupled to the RF input where the second impedance is provided, at least in part, by activating the first switch and a second switch in response to the rectified voltage satisfying the first voltage threshold and a second voltage threshold, respectively. | 09-26-2013 |
20130261703 | POWERING MULTIPLE IMPLANTABLE MEDICAL THERAPY DELIVERY DEVICES USING FAR FIELD RADIATIVE POWERING AT MULTIPLE FREQUENCIES - A system includes a first implantable medical device configured to receive a first far field radiative signal at a first frequency from an external transmitter to charge a first charge storage device. The first implantable medical device includes a first therapy delivery unit powered by the first charge storage device. The first therapy delivery unit delivers a first therapy to a first target tissue of a patient. The system also includes a second implantable medical device configured to receive a second far field radiative signal at a second frequency from the external transmitter to charge a second charge storage device. The second implantable medical device includes a second therapy delivery unit powered by the second charge storage device. The second therapy delivery unit delivers a second therapy to a second target tissue of the patient. | 10-03-2013 |
Patent application number | Description | Published |
20090310502 | Device and associated method for crosstalk estimation - The present invention relates to a crosstalk estimation device for estimating crosstalk between communication lines in a precoding group. The crosstalk estimation device comprises transmission means for transmitting a pilot sequence and reception means for receiving error feedback on one or more communication lines in the precoding group. The crosstalk estimation device further comprises crosstalk estimation means for combining the pilot sequence with the error feedback in order to obtain a crosstalk estimation between the communication lines. The device further comprises selection means for selecting a subset of one or more communication lines from the precoding group. The transmission means are adapted to transmit the pilot sequence only on the subset. | 12-17-2009 |
20120057693 | Joint Signal Processing Across A Plurality Of Line Termination Cards - In one embodiment, the line termination card includes a data output terminal configured to output a data sequence. The card further includes a vectoring entity configured to parse and encode the data sequence into frequency samples according to a carrier loading parameter, configured to scale the frequency samples into scaled frequency samples according to a carrier scaling parameter, and, configured to process the scaled frequency samples for crosstalk compensation. A controller is configured to adjust the carrier loading parameter and the carrier scaling parameter, and a forwarder is coupled to the data output terminal and to the controller. The forwarder is configured to forward the data sequence, the carrier loading parameter and the carrier scaling parameter towards a further line termination card. | 03-08-2012 |
20120106315 | Efficient Generation of Compensated Signals for Crosstalk Control in a Communication System - An access node of a communication system is configured to control crosstalk between channels of the system. Vectoring circuitry in the access node estimates crosstalk between channels of the system, generates a compressed representation of the crosstalk estimates, and generates compensated signals based on the compressed representation of the crosstalk estimates. The compressed representation comprises a value array and an index array, with the value array comprising selected values from each of a plurality of rows of a matrix representation of the crosstalk estimates, and the index array identifying locations of the selected values in the matrix representation of the crosstalk estimates. The compensated signals may be pre-compensated signals or post-compensated signals. | 05-03-2012 |
20130322885 | DOWN-SAMPLING CLOCK AND DATA RECOVERY CIRCUIT HAVING SELECTABLE RATE AND PHASE OUTPUT AND METHOD OF OPERATION THEREOF - A clock and data recovery (CDR) circuit, a method of recovering a clock and data from a received raw data stream and a BI-PON optical network transceiver (ONT) receiver front-end incorporating the CDR circuit. In one embodiment, the CDR circuit includes: (1) a line rate CDR circuit having a voltage controlled oscillator, the line rate CDR circuit configured to recover a raw data stream at a receiving line rate, (2) a fixed-rate down-sampler coupled to the line rate CDR circuit and configured to down-sample the raw data stream based on a fixed-rate and (3) a variable-rate down-sampler coupled to the fixed-rate down-sampler and configured further to down-sample the raw data sample based on a variable-rate. | 12-05-2013 |
Patent application number | Description | Published |
20090293055 | Central Office Based Virtual Personal Computer - A virtual personal computer is implemented in a communication system comprising a plurality of central offices each of which communicates with a plurality of client devices over a corresponding access network. A given one of the central offices comprises at least one compute server and at least one storage server. The virtual personal computer is configured by allocating physical processing resources of the compute server and physical storage resources of the storage server to that virtual personal computer. User access is provided to the virtual personal computer via one of the client devices. The virtual personal computer can be dynamically reconfigured by altering the allocation of at least one of the physical processing resources and the physical storage resources to the given virtual personal computer responsive to particular applications selected by the user to run on the given virtual personal computer. | 11-26-2009 |
20090296865 | METHODS AND APPARATUS FOR PROVIDING SYNCHRONIZATION IN A MULTI-CHANNEL COMMUNICATION SYSTEM - A multi-channel processing module is arranged in series with multiple channels of a communication system. The processing module synchronizes downstream symbols among the channels, and synchronizes downstream symbols for at least a given one of the channels with upstream symbols for that channel. The synchronization of downstream symbols among the channels and the synchronization of downstream symbols for at least the given channel with upstream symbols for that channel are collectively achieved by adjusting downstream and upstream adjustable delay elements associated with respective downlink and uplink signal paths in the multi-channel processing module. The channels may comprise respective subscriber lines of a DSL communication system. | 12-03-2009 |
20130089330 | Method And Apparatus For Efficient Operation Of A Passive Optical Communications Access Network - A method and apparatus for providing an efficient optical access network. In a preferred embodiment, a single light source is used to generate light in a network node, such as an OLT (optical line terminal). The generated light is then distributed using an optical splitter to a plurality of outputs, each associated with an ONU. The distributed light intended for a particular ONU (optical network unit) is modulated, for example by an EOM (electro-optical modulator), with a signal carrying communications for the intended ONU. The OLT includes a bank of EOMs or other kind of optical modulators, such as EAMs for serving a plurality of ONUs. The OLT may also include a second light source for generating light that is propagated to one or more of the ONUs for their use in forming upstream transmissions. | 04-11-2013 |
20140126919 | Method And Apparatus For Processing Bit-Interleaved Data Traffic In A Communication Network - A manner of processing bit-interleaved data traffic in a communication network. In the increasingly-common scenario where data traffic is bit interleaved and scrambled using a PRBS (pseudo-random binary sequence) before it is transmitted from a sender to a receiver, the receiver is configured to receive the transmitted bit stream and decimate it, that is, remove the bits of the bit stream that are allocated for the receiver, prior to descrambling. To accomplish this, the receiver employs an LFSR (linear feedback shift register) similar or identical to the one used by the sender to scramble the data. The LFSR is initialized by employing helper bits inserted by the sender or an initialization unit, and may employ other techniques for phase adjustment or state skipping depending on the nature of the transmitted bit stream. | 05-08-2014 |
Patent application number | Description | Published |
20120171165 | HUMAN MILK OLIGOSACCHARIDES TO PROMOTE GROWTH OF BENEFICIAL BACTERIA - Disclosed are nutritional compositions including human milk oligosaccharides that can be administered to individuals including preterm infants, infants, toddlers, and children for improving gastrointestinal function and tolerance, as well as the growth of beneficial bacteria. Additional suitable methods of using the nutritional compositions including the human milk oligosaccharides are also disclosed. | 07-05-2012 |
20120171166 | SYNBIOTIC COMBINATION OF PROBIOTIC AND HUMAN MILK OLIGOSACCHARIDES TO PROMOTE GROWTH OF BENEFICIAL MICROBIOTA - Disclosed are nutritional compositions including human milk oligosaccharides that can be administered to individuals including preterm infants, infants, toddlers, and children for improving gastrointestinal function and tolerance, as well as the growth of beneficial microbiota. Suitable additional methods of using the nutritional compositions including the human milk oligosaccharides are also disclosed. | 07-05-2012 |
20120172319 | METHODS FOR DECREASING THE INCIDENCE OF NECROTIZING ENTEROCOLITIS IN INFANTS, TODDLERS, OR CHILDREN USING HUMAN MILK OLIGOSACCHARIDES - Disclosed are methods of reducing the incidence of necrotizing enterocolitis in an infant, toddler, or child using nutritional compositions including human milk oligosaccharides. The nutritional compositions including the human milk oligosaccharides are effective in reducing inflammation and the incidence of inflammatory diseases. | 07-05-2012 |
20140249103 | HUMAN MILK OLIGOSACCHARIDES TO PROMOTE GROWTH OF BENEFICIAL BACTERIA - Disclosed are nutritional compositions including human milk oligosaccharides that can be administered to individuals including preterm infants, infants, toddlers, and children for improving gastrointestinal function and tolerance, as well as the growth of beneficial bacteria. Additional suitable methods of using the nutritional compositions including the human milk oligosaccharides are also disclosed. | 09-04-2014 |
20140294789 | GALACTOOLIGOSACCHARIDES FOR PREVENTING INJURY AND/OR PROMOTING HEALING OF THE GASTROINTESTINAL TRACT - Disclosed are nutritional compositions including galactooligosaccharides that can be administered to individuals including preterm infants, infants, toddlers, children, and adults for preventing injury and/or improving the healing of the gastrointestinal tract. Additional suitable methods of using the nutritional compositions including the galactooligosaccharides are also disclosed. | 10-02-2014 |
Patent application number | Description | Published |
20120198374 | DRAG AND DROP INTERACTION BETWEEN COMPONENTS OF A WEB APPLICATION - A user of a web application can perform a drag and drop operation from a first component of the web application to a second component of the web application. The drag and drop operation can include three actions. The first action can be initializing a drag of an object within a first component of a web application. The second action can be dragging the object from within the first component over a drop target located within a second component of the web application. The third action can be dropping the object onto the drop target located within the second component of the web application. One of the first and second components can be a web component, and the other component can be a visualization component. The first and second components of the web application can communicate with each other using a communication component of the web application. | 08-02-2012 |
20120293516 | KEYBOARD NAVIGATION AMONG VISUAL ELEMENTS IN A USER INTERFACE - A system navigates among visual elements of a user interface. The system receives a keystroke indicating navigating from a current visual element in a first direction, determines a next visual element that is substantially near the current visual element and in the first direction, and navigates to the next visual element. | 11-22-2012 |
20120297327 | INTERACTIVE CUSTOM REGIONS - One embodiment is directed to a computer program, embodied on a computer readable medium. The computer program is configured to control a processor to execute instructions. The instructions include receiving a selection of built-in interactive regions provided by a visualization component, aggregating the selected set of regions, and creating one or more custom regions from the aggregation of the selected set of regions. | 11-22-2012 |
20130083056 | INTERACTIVE DISPLAY ELEMENTS IN A VISUALIZATION COMPONENT - One embodiment is directed to a computer program, embodied on a computer readable medium. The computer program is configured to control a processor to execute instructions. The instructions include receiving one or more files as input. The files may each include descriptions of different shapes. The instructions may further include interpreting each of the files as a layer of shapes, converting each of the shapes into an interactive element, layering the converted shapes onto one another to create a custom interactive display, and displaying the custom interactive display. | 04-04-2013 |
Patent application number | Description | Published |
20090035378 | NANOSTRUCTURED BIOACTIVE MATERIALS PREPARED BY DUAL NOZZLE SPRAY DRYING TECHNIQUES - Nano-particles of calcium and phosphorous compounds are made in a highly pure generally amorphous state by spray drying a weak acid solution of said compound and evaporating the liquid from the atomized spray in a heated column followed by collection of the precipitated particles. Hydroxyapatite (HA) particles formed by such apparatus and methods are examples of particle manufacture useful in bone and dental therapies. Dual nozzle spraying techniques are utilized for generally insoluble compounds. | 02-05-2009 |
20090093566 | Dental releasing materials - Combining nanosized particles of a source of desired dental restorative, repair or therapeutic materials with strengthening agents in various generally nanosized form such as whiskers, fibers, particles and the like in a resin matrix provides a highly strain resistant composite which more effectively releases the therapeutic agents. The utilization of nano sized particles of the therapeutic agent in the combination enables observation of significantly improved therapeutic results. | 04-09-2009 |
20100269736 | Dual-Phase Calcium Phosphate Cement Composition - Disclosed are dual-phase cement precursor systems and associated methods and kits. The cement precursor systems comprises at least first and second phases each containing a calcium phosphate compound. When mixed, the first and second cement precursor phases form a biocompatible cement. The disclosed systems include an organic acid in an amount effective to enhance the working time of the cement precursor composition, and also include a setting accelerator. In some embodiments, one or more of the calcium phosphate compounds is provided in the form of particles with a nonmonomial particle sized distribution. | 10-28-2010 |
20120217665 | Method for Preparation of Well-Dispersed, Discrete Nanoparticles by Spray Drying Techniques - A method for preparing uniquely sized nanoparticles of CaF | 08-30-2012 |
Patent application number | Description | Published |
20110016221 | Brokerage Transaction Server and Method Using Encapsulated Messages - Brokerage transactions servers and related methods are provided having low latency. In a first embodiment of the invention there is provided a method of processing exchange transaction information for exchange brokerage purposes in an inbound digital message stream in a first protocol dialect. One embodiment utilizes canonical FIX messages for processing purposes. A related embodiment includes, for each message in the stream, storing in memory each successive change made to the message and any metadata created by the foregoing processes; and in an encapsulation process, accessing memory and creating an encapsulated version of the message that includes: (i) the message in original form prior to the receiver process, (ii) the metadata, and (iii) each successive change made to the message by any of the foregoing processes. | 01-20-2011 |
20110178915 | Trading Order Validation System and Method and High-Performance Trading Data Interface - A post-trade monitor receives feedback in the form of drop copy messages from an exchange server and validates orders placed with the exchange server by a sponsored access trading platform shortly after the orders have been placed. If a recently placed order is found to violate a rule or regulation, the monitor instructs the trading platform to change to a more restrictive trading mode, such as to cease placing all orders or certain types of orders, at least until certain parameters are met. A library provides an interface in a sponsored access trading platform between a client application program that generates proposed orders and an exchange server. The library provides pre-trade validation of the orders and sends only validated orders to the exchange server. A network enables monitors, trading platforms and libraries to share information about customers' trading activities and locally recalculate customer trading limits resulting from these trading activities. A low-latency interface between a customer server, such as a server that employs algorithmic trading methods to generate buy and sell orders for securities, and a brokerage server that validates such securities trading orders is optimized for handling the securities trading orders. The interface supports a trading command set specifically designed for orders from customer trading application programs, and the interface formats received trading commands into compact messages that are sent over a high-speed communication link to the brokerage server. The interface receives order acknowledgement messages and the like from the brokerage server and invokes callback routines in the customer trading application program to report status information. | 07-21-2011 |
20110196778 | High Performance Trading Data Interface and Trading Data Distribution Protocol - A network enables monitors, trading platforms and libraries to share information about customers' trading activities and locally recalculate customer trading limits resulting from these trading activities. A low-latency interface between a customer server, such as a server that employs algorithmic trading methods to generate buy and sell orders for securities, and a brokerage server that validates such securities trading orders is optimized for handling the securities trading orders. The interface supports a trading command set specifically designed for orders from customer trading application programs, and the interface formats received trading commands into compact messages that are sent over a high-speed communication link to the brokerage server. The interface receives order acknowledgement messages and the like from the brokerage server and invokes callback routines in the customer trading application program to report status information. | 08-11-2011 |
20140025558 | Trading Control System that Shares Customer Trading Activity Data Among Plural Servers - A network enables a plurality of servers to share information about customers' trading activities and locally recalculate customer trading limits resulting from these trading activities. If a trading limit is exceeded, a server may automatically change to a less permissive trading mode, prevent an order being placed with the at least one exchange server and/or enter a trading mode in which orders that decrease account exposure are allowed and orders that increase account exposure are prevented. | 01-23-2014 |
20140108228 | Trading Order Validation System and Method and High-Performance Trading Data Interface - A post-trade monitor receives feedback in the form of drop copy messages from an exchange server and validates orders placed with the exchange server by a sponsored access trading platform shortly after the orders have been placed. If a recently placed order is found to violate a rule or regulation, the monitor instructs the trading platform to change to a more restrictive trading mode, such as to cease placing all orders or certain types of orders, at least until certain parameters are met. | 04-17-2014 |
Patent application number | Description | Published |
20130042302 | COGNITIVE PATTERN RECOGNITION FOR COMPUTER-BASED SECURITY ACCESS - Implementing security access includes receiving a request to perform an activity over a network and administering a cognitive test responsive to the request that includes a set of images and an instruction to identify a cognitive pattern in the set of images. Implementing the security access also includes processing results of the cognitive test, and executing the activity when it is determined from the processing that the cognitive test has been successfully completed. | 02-14-2013 |
20130042303 | COGNITIVE PATTERN RECOGNITION FOR SECURITY ACCESS IN A FLOW OF TASKS - Implementing security access includes receiving a request to perform an activity over a network and administering a cognitive test responsive to the request. The administering includes randomly selecting a set of related images from a database of images, randomly selecting one image that is unrelated to the set of related images, displaying the set of related images along with the image that is unrelated to the set of related images, and prompting a user to identify the image that is unrelated to the set of related images. Implementing the security access also includes processing results of the cognitive test, and executing the activity when it is determined from the processing that the cognitive test has been successfully completed. | 02-14-2013 |
20130212662 | SECURITY ACCESS IN A COMPUTER-BASED FLOW OF TASKS - Implementing security access includes creating a coordinate system that includes a first axis and a second axis. Points on the first axis and the second axis specify corresponding coordinates. The security access also includes randomly selecting values from a database and populating the coordinate system with the values and selecting a set of the coordinates from the coordinate system. The set of coordinates is indicative of an instruction. The security access further includes generating an image from the coordinate system and the values, the image including labels for the coordinates along respective first axis and second axis, and identifying values corresponding to the set of coordinates. The values correspond to the set of coordinates indicative of an answer to the instruction. The security access also includes transmitting the image and the instruction to a user device, and using the image, the instruction, and the answer as a security access mechanism. | 08-15-2013 |
20130311641 | TRAFFIC EVENT DATA SOURCE IDENTIFICATION, DATA COLLECTION AND DATA STORAGE - Traffic event data source identification embodiments comprise a first monitoring system that detects a traffic event, a communication device that broadcasts a discovery signal and receives back response signals from any second monitoring systems within the vicinity of the traffic event, and a memory that stores a list of responding second monitoring systems. Traffic event data collection embodiments incorporate the identification embodiments and additional features. In this case, the first monitoring system captures data recorded at the time of the traffic event and a second communication device transmits this data and, optionally, the list to a traffic event database in a traffic event data storage system. The first communication device also transmits a data capture request signal to the second monitoring system(s) requesting capture of any data recorded at the time of the traffic event and, optionally, requesting that such data be transmitted to the database. | 11-21-2013 |
Patent application number | Description | Published |
20110172175 | PROCESS AND COMPOSITION FOR COATING PROPAGATION MATERIAL - The present invention provides a process for coating a plant propagation material, including a seed, comprising: a.) providing a propagation material, such as seed, to be coated; b.) applying to the propagation material a composition comprising at least one reactant having reactive functionality and, optionally, at least one active ingredient; and c.) polymerising, crosslinking, curing or otherwise reacting the reactant having reactive functionality on the surface of the plant propagation material to form a coating thereon which may encompass an a.i., when present. The present invention further provides a method for enhancing the safety, quality and/or viability of a plant propagation material, including a seed, comprising providing a coated material having less dust-off. | 07-14-2011 |
20140162880 | Controlled Release Granules - The present invention relates to a controlled release granule technology, methods of preparing such a granule and methods for using the granule in the control of pests. | 06-12-2014 |