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Choo, Singapore
Andre Choo, Singapore SG
| Patent application number | Description | Published |
|---|---|---|
| 20090214490 | HUMAN EMBRYONIC STEM CELL METHODS AND PODXL EXPRESSION - A method of identifying an undifferentiated human embryonic stem cell in a sample which may contain such cells, the method comprising identifying the cell or cells within the sample that express podocalyxin-like protein (PODXL) on their surface. A method of isolating an undifferentiated human embryonic stem cell from a sample containing such cells, the method comprising isolating the cell or cells within the sample that express PODXL on their surface. Typically, the methods use an antibody which binds to PODXL. Undifferentiated human embryonic stem cells isolated by the method may be useful in cell therapy. Also, in particular, compositions of cells differentiated from a human embryonic stem cell but which composition has been depleted of undifferentiated human embryonic stem cells are provided which are useful in cell therapy. | 08-27-2009 |
| 20100093053 | Microcarriers for Stem Cell Culture - We disclose a particle comprising a matrix coated thereon and having a positive charge, the particle being of a size to allow aggregation of primate or human stem cells attached thereto. The particle may comprise a substantially elongate, cylindrical or rod shaped particle having a longest dimension of between 50 μm and 400 μm, such as about 200 μm. It may have a cross sectional dimension of between 20 μm and 30 μm. The particle may comprise a substantially compact or spherical shaped particle having a size of between about 20 μm and about 120 μm, for example about 65 μm. We also disclose a method of propagating primate or human stem cells, the method comprising: providing first and second primate or human stem cells attached to first and second respective particles, allowing the first primate or human stem cell to contact the second primate or human stem cell to form an aggregate of cells and culturing the aggregate to propagate the primate or human stem cells for at least one passage. A method of propagating human embryonic stem cells (hESCs) in long term suspension culture using microcarriers coated in Matrigel or hyaluronic acid is also disclosed. We also disclose a method for differentiating stem cells. | 04-15-2010 |
| 20110014693 | Microcarriers For Stem Cell Culture - We disclose a particle comprising a matrix coated thereon and having a positive charge, the particle being of a size to allow aggregation of primate or human stem cells attached thereto. The particle may comprise a substantially elongate, cylindrical or rod shaped particle having a longest dimension of between 50 μm and 400 μm, such as about 200 μm. It may have a cross sectional dimension of between 20 μm and 30 μm. The particle may comprise a substantially compact or spherical shaped particle having a size of between about 20 μm and about 120 μm, for example about 65 μm. We also disclose a method of propagating primate or human stem cells, the method comprising: providing first and second primate or human stem cells attached to first and second respective particles, allowing the first primate or human stem cell to contact the second primate or human stem cell to form an aggregate of cells and culturing the aggregate to propagate the primate or human stem cells for at least one passage. A method of propagating human embryonic stem cells (hESCs) in long term suspension culture using microcarriers coated in Matrigel or hyaluronic acid is also disclosed. We also disclose a method for differentiating stem cells. | 01-20-2011 |
Andre Boon Hwa Choo, Singapore SG
| Patent application number | Description | Published |
|---|---|---|
| 20090029461 | Immortalised Feeder Cells - The invention relates to an immortalized feeder cell line. The immortalized feeder cell line may be derived from an embryonic fibroblast, which may be a mouse embryonic fibroblast. A culture of an immortalized feeder cell line according to the invention in a suitable culture medium is also provided, as is a composition including an immortalized feeder cell line according to the invention in a suitable carrier or diluent and conditioned medium produced from growth of an immortalized feeder cell line according to the invention. The invention further provides a method of culturing a stem cell including use of a cell line or conditioned medium according to the invention and cells so produced. | 01-29-2009 |
Boon Hwa Andre Choo, Singapore SG
| Patent application number | Description | Published |
|---|---|---|
| 20080199463 | METHOD FOR TREATING MULTIPLE MYELOMA - The present invention relates to methods for the treatment of multiple myeloma. More particularly, the present invention relates to a method for inducing apoptosis in myeloma cells by administration of a K121-like antibody. | 08-21-2008 |
| 20090263358 | METHOD FOR TREATING MULTIPLE MYELOMA - The present invention relates to methods for the treatment of multiple myeloma. More particularly, the present invention relates to a method for inducing apoptosis in myeloma cells by administration of a K121-like antibody. | 10-22-2009 |
| 20110171183 | Markers of Induced Pluripotent Stem Cells - The disclosure relates to the expression of podocalyxin-like protein (PODXL) on the surface of induced pluripotent stem cells and particularly, although not exclusively, to the use of PODXL as a marker of induced pluripotent stem cells. | 07-14-2011 |
Boon Siang Choo, Singapore SG
| Patent application number | Description | Published |
|---|---|---|
| 20090125752 | Systems And Methods For Managing A Redundant Management Module - Systems and methods for managing a redundant management module are provided. In this regard, a representative system, among others, includes first and second management modules that are configured to manage a computing device; and a programmable logic device that is configured to: instruct the first management module to manage the computing device responsive to detecting that the first management module is ready to manage the computing device, and instruct the second management module to manage the computing device responsive to detecting that the first management module failed to manage the computing device. | 05-14-2009 |
Guan Chuan Choo, Singapore SG
| Patent application number | Description | Published |
|---|---|---|
| 20080276158 | System for Downloading Digital Content Published in a Media Channel - There is provided a system for downloading digital content to a portable media player, the digital content being published in a media channel by a content creator. The system may reside on a server accessible via the Internet. The system may comprise: a data receiver module to receive the digital content from the media channel via a communication medium; a conversion module to convert the received digital content to at least one format for consumption by the player; and a download module to copy the at least one file to the portable media player. The system may further comprise a player detection module to detect file formats compatible with the portable media player. A corresponding method is also disclosed. | 11-06-2008 |
Poo Dee Choo, Singapore SG
| Patent application number | Description | Published |
|---|---|---|
| 20090142117 | KEYBOARD WITH EXTENDED CONNECTION - A keyboard for use with a host computer is disclosed. The keyboard has a main portion with a processor and a driver; and an auxiliary portion releasably connected to the main portion and being operatively connected to the processor by a cable. The processor and the driver of the main portion are used for the operation of the auxiliary portion. | 06-04-2009 |
Quek Leong Choo, Singapore SG
| Patent application number | Description | Published |
|---|---|---|
| 20090034380 | PARTIAL-BLOCK OFF-TRACK DATA RECOVERY - Techniques for data recovery from a data block wherein portions of the data block are written at different off-track positions are described. For example, portions of a data block can be read separately for each on-track and off-track position in the data block; then, the separately read portions can be recombined into a recovered data block. | 02-05-2009 |
Sung Woon Choo, Singapore SG
| Patent application number | Description | Published |
|---|---|---|
| 20090026568 | OPTICAL COLOR SENSOR SYSTEM - An optical color sensor system is provided including providing a substrate having an optical sensor therein and forming a passivation layer over the substrate. The passivation layer is planarized and color filters are formed over the passivation layer. A planar transparent layer is formed over the color filters and microlenses are formed on the planar transparent layer over the color filters. | 01-29-2009 |
Wee Boon Choo, Singapore SG
| Patent application number | Description | Published |
|---|---|---|
| 20090028240 | Encoder, Decoder, Method for Encoding/Decoding, Computer Readable Media and Computer Program Elements - An encoder for encoding a first digital signal representative for a first channel and a second digital signal representative for a second channel is described. The encoder comprises cascaded intra-channel prediction elements for compressing the first digital signal and the second digital signal based on intra-channel correlation and an inter-channel prediction element for compressing the first digital signal and the second digital signal based on inter-channel correlation. | 01-29-2009 |
| 20100023575 | PREDICTOR - A Predictor is described which is based on a modified RLS (recursive least squares) algorithm. The modifications prevent divergence and accuracy problems when fixed point implementation is used. | 01-28-2010 |
Wei Fern Choo, Singapore SG
| Patent application number | Description | Published |
|---|---|---|
| 20110268913 | Composite Board - A composite board ( | 11-03-2011 |
Wei Hsien Choo, Singapore SG
| Patent application number | Description | Published |
|---|---|---|
| 20100124766 | Apparatus and Method for Segmented Thermal Cycler - The present invention relates to a thermal cycler for the carrying out of chemical or biological reactions, such as PCR or other nucleic acid amplification reactions, that is segmented with a plurality of reaction vessel receiving elements. The reaction vessel receiving elements are thermally isolated from each other and provide an airtight seal to prevent liquids or moisture from penetrating below the reaction vessel receiving elements. The reaction vessel receiving elements have several recesses arranged in a pattern to receive the reaction vessels of a single standard microtiter plate and the segmented thermal cycler has a system for independently heating and cooling each of the reaction vessel receiving elements. | 05-20-2010 |
William Choo, Singapore SG
| Patent application number | Description | Published |
|---|---|---|
| 20110148981 | DETECTING AND REMOVING FIBERS - In one embodiment, a method to detect and remove fibers comprises identifying blocked nozzles in a grouping of nozzles within a printhead, and triggering a fiber removal event if it is determined that a plurality of adjacent nozzles are blocked. | 06-23-2011 |
Yoo Sang Choo, Singapore SG
| Patent application number | Description | Published |
|---|---|---|
| 20090217855 | PONTOON-TYPE FLOATING STRUCTURE - A pontoon-type floating structure comprising an upper deck that is to be maintained above water level and that is to receive and support a load by the load resting thereon; and a horizontal array of chambers disposed underneath the upper deck, with the chambers providing a first set of chambers that provide the structure with buoyancy, and a second set of chambers with water having access thereto so that the second set of chambers, under steady state conditions, do not provide buoyancy. | 09-03-2009 |