Patent application number | Description | Published |
20120142109 | METHOD FOR PRODUCING T CELL POPULATION UNDER PRESENCE OF RETINOIC ACID - Disclosed is a method for producing a cell population containing memory-like T cells, said method being characterized by including a step for in vitro culturing of a cell population containing T cells or T cell precursor cells using a retinoic acid and a CD3 ligand. Further disclosed is a method for producing a cell population wherein the proportion of memory-like T cells is increased and wherein a desired gene is introduced with a high efficiency and is highly expressed. | 06-07-2012 |
20130109096 | METHOD FOR GENE TRANSFER | 05-02-2013 |
20130142766 | PRODUCTION METHOD FOR CELL POPULATIONS - The present invention addresses the problem of providing cell populations having a high proportion of CD4-positive naive T cells and/or CD4-positive central memory T cells, and a production method thereof. The present invention provides a production method for CD4-positive T cell populations which is characterized by using anti-CD3 antibodies, fibronectin fragments, and Interleukin-4. The method is characterized not only by the attainment of a cell group with a high proportion of CD4-positive naive T cells and/or CD4-positive central memory T cells, but also by a high bulk yield. | 06-06-2013 |
20140170709 | VECTOR FOR GENE THERAPY - The present invention provides a retroviral vector containing a transcription unit comprising a transcription regulatory sequence and a gene encoding a polypeptide having single-stranded RNA-specific endoribonuclease activity which is placed so that its expression can be controlled by the regulatory sequence, wherein the unit is placed so that the direction of the transcription of mRNA from the unit is opposite to the direction of transcription of the RNA genome of the retroviral vector. By using the vector constructed as described above, viral supernatant showing high gene transfer efficiency can be prepared. The retroviral vector of the present invention is useful for the treatment and/or prevention of cancers and virus infections. | 06-19-2014 |
20140349404 | METHOD FOR GENE TRANSFER - Disclosed is a simple and highly efficient method for introducing a gene into a target cell using a retrovirus vector. The method comprises the steps of (a) placing a liquor containing a retrovirus vector having a foreign gene carried thereon into a bag for cell culture on which a retrovirus-binding substance has been immobilized, and incubating the liquor at a temperature lower than 25° C. for 8-48 hours, thereby producing a culture bag having the retrovirus vector bound thereto, (b) adding a target cell to the culture bag that has been produced in step (a) and incubating the culture bag for 8 hours or less, and (c) flipping the culture bag upside down and incubating the culture bag. The gene introduction method is useful particularly in medicine, cell technology, gene technology, and embryologic technology. | 11-27-2014 |
20150037300 | NUCLEIC ACID FOR TREATMENT OR PREVENTION OF IMMUNODEFICIENCY VIRUS INFECTION - A nucleic acid comprising a transcription regulation sequence whose transcription is induced by a trans-acting factor of a human immunodeficiency virus and a gene encoding a polypeptide having an endoribonuclease activity specific to single-stranded RNA, wherein the gene is located in such a position that the expression of the gene can be regulated by the transcription regulation sequence; a method for production of a cell showing an inhibited replication of a human immunodeficiency virus therein, the method comprising the step of introducing the nucleic acid into a cell; and a method for treatment or prevention of a human immunodeficiency virus infection. | 02-05-2015 |
Patent application number | Description | Published |
20080293141 | Cell for Producing Retrovirus Vector - The N-acetylglucosaminyltransferase III activity is enhanced in a cell carrying retrovirus-origin gag-pol gene and env gene. By constructing a retrovirus vector with the use of the above cell, a retrovirus vector having a modified sugar chain structure can be obtained. The retrovirus vector constructed by this method shows a high infection efficiency particularly in the presence of a functional substance. | 11-27-2008 |
20090011485 | METHOD OF RETROVIRUS STORAGE - A method of retrovirus storage, characterized in that a retrovirus is sustained in the presence of a substance with retrovirus binding activity immobilized on a solid phase. Further, there is provided a retrovirus composition characterized in that a retrovirus in the form of binding to a substance with retrovirus binding activity is sealed in a container holding a solid phase having the substance with retrovirus binding activity immobilized thereon. | 01-08-2009 |
20100113566 | NUCLEIC ACID FOR TREATMENT OR PREVENTION OF IMMUNODEFICIENCY VIRUS INFECTION - A nucleic acid comprising a transcription regulation sequence whose transcription is induced by a trans-acting factor of a human immunodeficiency virus and a gene encoding a polypeptide having an endoribonuclease activity specific to single-stranded RNA, wherein the gene is located in such a position that the expression of the gene can be regulated by the transcription regulation sequence; a method for production of a cell showing an inhibited replication of a human immunodeficiency virus therein, the method comprising the step of introducing the nucleic acid into a cell; and a method for treatment or prevention of a human immunodeficiency virus infection. | 05-06-2010 |
20100136680 | BAGLIKE CONTAINER FOR CENTRIFUGATION AND METHOD OF GENE TRANSFER USING THE SAME - Baglike container ( | 06-03-2010 |
20100137415 | VECTOR FOR GENE THERAPY - The present invention provides a retroviral vector containing a transcription unit comprising a transcription regulatory sequence and a gene encoding a polypeptide having single-stranded RNA-specific endoribonuclease activity which is placed so that its expression can be controlled by the regulatory sequence, wherein the unit is placed so that the direction of the transcription of mRNA from the unit is opposite to the direction of transcription of the RNA genome of the retroviral vector. By using the vector constructed as described above, viral supernatant showing high gene transfer efficiency can be prepared. The retroviral vector of the present invention is useful for the treatment and/or prevention of cancers and virus infections. | 06-03-2010 |
20130102048 | METHOD OF RETROVIRUS STORAGE - A method of retrovirus storage, characterized in that a retrovirus is sustained in the presence of a substance with retrovirus binding activity immobilized on a solid phase. Further, there is provided a retrovirus composition characterized in that a retrovirus in the form of binding to a substance with retrovirus binding activity is sealed in a container holding a solid phase having the substance with retrovirus binding activity immobilized thereon. | 04-25-2013 |
Patent application number | Description | Published |
20120307898 | VIDEO ENCODING DEVICE AND VIDEO DECODING DEVICE - To efficiently reduce contour and stair-step artifacts. | 12-06-2012 |
20130101037 | VIDEO ENCODING DEVICE, VIDEO DECODING DEVICE, VIDEO ENCODING METHOD, VIDEO DECODING METHOD, AND PROGRAM - A video encoding device includes: pixel bit length increasing means for increasing a pixel bit length of an input image based on pixel bit length increase information; transform means for transforming output data of the pixel bit length increasing means; entropy encoding means for entropy-encoding output data of the transform means; non-compression encoding means for non-compression-encoding input data; multiplexed data selection means for selecting output data of the entropy encoding means or output data of the non-compression encoding means; and multiplexing means for multiplexing the pixel bit length increase information in a bitstream, wherein a pixel bit length of an image corresponding to the output data of the entropy encoding means and a pixel bit length of an image corresponding to the output data of the non-compression encoding means are different from each other. | 04-25-2013 |
20130114690 | VIDEO ENCODING DEVICE AND VIDEO DECODING DEVICE - To efficiently reduce contour and stair-step artifacts. | 05-09-2013 |
20130121407 | VIDEO ENCODING DEVICE AND VIDEO DECODING DEVICE - A video encoding device and a video decoding device prevent an increase in the number of lines of a reference line buffer in a pseudo random noise injection process. The video encoding device includes: an inverse quantization unit for inverse-quantizing a quantization index to obtain a quantization representative value; an inverse frequency transform unit for inverse-transforming the quantization representative value obtained by the inverse quantization unit, to obtain a reconstructed image block; and an asymmetrical distortion removal filter unit for injecting pseudo random noise to an area asymmetrical about a boundary of the reconstructed image block. | 05-16-2013 |
20130223514 | VIDEO ENCODING DEVICE, VIDEO DECODING DEVICE, VIDEO ENCODING METHOD, VIDEO DECODING METHOD, AND PROGRAM - A video encoding device includes: transform means | 08-29-2013 |
20130259121 | VIDEO ENCODING DEVICE, VIDEO DECODING DEVICE, VIDEO ENCODING METHOD, VIDEO DECODING METHOD, AND PROGRAM - A video encoding device includes an intra prediction unit for performing intra prediction on an image, a frequency transform/quantization unit for frequency transform and quantizing a prediction error based on the intra prediction performed by the intra prediction unit, an entropy encoding unit for entropy-encoding a transform quantization value generated by the frequency transform/quantization unit, an edge detection unit for detecting edge information on an image block of the minimum frequency-transform block size of the image, and edge information storage unit for storing the edge information detected by the edge detection unit. | 10-03-2013 |
20130294510 | VIDEO ENCODING DEVICE, VIDEO DECODING DEVICE, VIDEO ENCODING METHOD, VIDEO DECODING METHOD, AND PROGRAM - A video encoding device includes a planar prediction unit using planar prediction, and a noise injecting unit for injecting pseudo-random noise into a prediction image of a planar prediction block when a reconstructed prediction error value for planar prediction is less than a threshold determined by the size of the planar prediction block. The video encoding device then uses the pseudo-random noise in linear interpolation for calculating the prediction image, based on the conditions under which a gradient distortion occurs, to suppress the gradient distortion. | 11-07-2013 |
20130322542 | VIDEO ENCODING DEVICE, VIDEO DECODING DEVICE, VIDEO ENCODING METHOD, VIDEO DECODING METHOD, AND PROGRAM - A video encoding device includes encoding control means | 12-05-2013 |
20130336397 | VIDEO ENCODING DEVICE, VIDEO DECODING DEVICE, VIDEO ENCODING METHOD, VIDEO DECODING METHOD, AND PROGRAM - A video encoding device for encoding video using inter prediction includes encoding control means | 12-19-2013 |
20140056349 | IMAGE ENCODING DEVICE AND IMAGE DECODING DEVICE - A video encoding device includes: a quantization step size encoding unit | 02-27-2014 |
20140105282 | METHOD FOR CODING VIDEO QUANTIZATION PARAMETER AND METHOD FOR DECODING VIDEO QUANTIZATION PARAMETER - A video quantization parameter encoder includes: a prediction unit | 04-17-2014 |
20140286398 | IMAGE QUANTIZATION PARAMETER ENCODING METHOD AND IMAGE QUANTIZATION PARAMETER DECODING METHOD - An image quantization parameter encoder includes: a prediction unit | 09-25-2014 |
Patent application number | Description | Published |
20090216124 | ULTRASONIC DIAGNOSTIC APPARATUS AND IMAGE PROCESSING METHOD THEREOF - An ultrasonic diagnostic apparatus includes means for transmitting/receiving ultrasonic waves to/from an object to be examined and capturing a dynamic image of the object. | 08-27-2009 |
20100022877 | ULTRASONOGRAPHIC DEVICE - An ultrasonographic device includes a template conversion unit ( | 01-28-2010 |
20110082371 | MEDICAL IMAGE PROCESSING DEVICE AND MEDICAL IMAGE PROCESSING METHOD - An ultrasonic diagnostic, apparatusi in accordance with the invention includes: an image information obtaining section configured to obtain multiple medical images in which a living tissue of a subject to be tested is imaged; and an image recognition calculation section configured to obtain motion information of the living tissue from pixel values of medical images at different time phases of the obtained multiple medical images and classify the medical images into predetermined types based on the motion information. | 04-07-2011 |
20110178405 | ULTRASONIC DIAGNOSTIC APPARATUS AND IMAGE PROCESSING APPARATUS FOR ULTRASONIC DIAGNOSIS - An ultrasonic diagnostic apparatus including means that acquires a three-dimensional ultrasonic signal of an internal organ of an examinee, means that sets a direction of a two-dimensional standard cross-section of the internal organ; means that adjusts display parameter of an image of a site which an examinee intends to observe, means that generates a two-dimensional standard cross-sectional image from the three-dimensional ultrasonic signal on the basis of the set direction of the two-dimensional standard cross-section of the internal organ, means that generates an observation cross-sectional image and a rendering image from the three-dimensional ultrasonic signal on the basis of the display parameters of the adjusted image, and display means that combines and displays the two-dimensional standard cross-sectional image, the observation cross-sectional image and the rendering image. | 07-21-2011 |
20110301454 | MEDICAL IMAGE DISPLAY METHOD, MEDICAL IMAGE DIAGNOSTIC APPARATUS, AND MEDICAL IMAGE DISPLAY DEVICE - Disclosed is a medical image display method for displaying a tomographic image obtained by scanning an image of a cross-section of an organ of an object and finding the volume of an inner cavity region surrounded by the inner wall surface of the inner cavity of the organ on the basis of the displayed tomographic image, comprising a step that segmentizes the inner cavity region into a first inner cavity region and a second inner cavity region, a step that calculates volume of the first inner cavity using the disk method, a step that calculates volume of the second inner cavity region using the pseudo disk method, a step that calculates the entire inner cavity volume by summing the calculated volumes of the first and the second inner cavity, and a step that displays the first and the second inner cavity volumes and/or the entire inner cavity volume. | 12-08-2011 |
20110313291 | MEDICAL IMAGE PROCESSING DEVICE, MEDICAL IMAGE PROCESSING METHOD, MEDICAL IMAGE DIAGNOSTIC APPARATUS, OPERATION METHOD OF MEDICAL IMAGE DIAGNOSTIC APPARATUS, AND MEDICAL IMAGE DISPLAY METHOD - A medical image processing device of the invention includes: an image acquisition unit that acquires three-dimensional image data including a moving organ; an image display unit that displays the three-dimensional image data as a three-dimensional image; an object-to-be-measured setting unit that sets a desired object to be measured on the three-dimensional image displayed on the image display unit; a diagnostic index calculating unit that calculates the amount of displacement of the three-dimensional image data in each time phase for the desired object to be measured and calculates a diagnostic index on the basis of the amount of displacement calculated in each time phase; and a control unit that performs control to display the diagnostic index on the image display unit. | 12-22-2011 |
20120014588 | MEDICAL IMAGE DIANOSTIC DEVICE, REGION-OF-INTERST SETTING METHOD, AND MEDICAL IMAGE PROCESSING DEVICE - The medical image diagnosis device of the invention includes image generating means configured to obtain image data of a tissue of an object and generate an image of the tissue of the object based on the image data, calculation means configured to calculate at least one of brightness and motion vectors of plural measurement points of the generated image, input means configured to specify an observation region of the image, a database in which a characteristic amount of at least one of the brightness and the motion vectors of the measurement points in respective images of plural different observation regions is set and stored in advance, checking means configured to read the characteristic amount of the observation region that is specified through the input means from the database and check the characteristic amount with results of calculation performed on the generated image by the calculation means, and ROI setting means configured to set a region of interest in the generated image based on checked results of the checking means. | 01-19-2012 |
20120027276 | MEDICAL IMAGE DIAGNOSTIC APPARATUS AND VOLUME CALCULATING METHOD - A medical image diagnostic apparatus provided with an image acquisition unit configured to acquire in-vivo information about an object to be examined as a medical image, a display unit configured to display the medical image, a setting unit configured to set a target region of volume measurement in the medial image displayed on the display unit, a calculation unit configured to perform calculation to split the target region into a plurality of volume elements, calculate the moving distance of the vertices of the volume elements when the target region of the acquired medical image moves, calculate the volumes of the volume elements after the movement using the calculated moving distance of the vertices, totalizing the calculated volumes of the volume elements after the movement and using the total volume as the volume of the target region, and a control unit configured to display the volume of the target region on the display unit. | 02-02-2012 |
20120065499 | MEDICAL IMAGE DIAGNOSIS DEVICE AND REGION-OF-INTEREST SETTING METHOD THEREFORE - A medical image diagnosis device according to the present invention has a medical image acquiring unit that acquires a medical image, a three-dimensional image constructing unit that constructs a three-dimensional image containing a motional internal organ region in the medical image, a sectional image generator that generates a two-dimensional sectional image serving as a reference image from the three-dimensional image, a region dividing unit that divides the reference image into plural regions on the basis of a criterion for region division, and a region-of-interest setting unit that calculates motion states of the plural regions, specifies at least one region of the plural regions on the basis of the calculated motion states, and sets as a region of interest a region of the medical image in which the specified region is contained. | 03-15-2012 |
20120083698 | ULTRASONIC DIAGNOSTIC APPARATUS AND INTIMA-MEDIA THICKNESS MEASURING METHOD THEREFOR - Disclosed is an ultrasonic diagnostic apparatus provided with an imaging unit configured to obtain an ultrasonic image of a carotid artery portion of an object to be examined, a parting line calculation unit configured to set at least one threshold value and calculate a parting line for segmenting the ultrasonic image into multiple regions, an intima-media thickness calculation unit configured to specify a direction for searching the multiple regions, search an intima-media region in the specified direction based on the brightness, draw multiple curves based on the position acquired by the search and positional information on the carotid artery portion in the ultrasonic image, and calculate the intima-media thickness from the distance between the multiple curves. | 04-05-2012 |
20120130245 | ULTRASONIC DIAGNOSTIC APPARATUS AND REGION-OF-INTEREST - Disclose is an ultrasonic diagnostic apparatus which transmits/receives an ultrasonic wave to/from a region including a carotid artery of an object, images an ultrasonic image, and comprises a thickness measurement unit configured to measure the thickness of an intima-media complex from the ultrasonic image, the ultrasonic diagnostic apparatus being provided with a region-of-interest setting unit configured to scan the ultrasonic image and set a region of interest including the intima-media complex on the ultrasonic image on the basis of the degree of concentration of contour slate points of the carotid artery, wherein the thickness measurement unit measures the thickness of the intima-media complex on the basis of boundaries within the set region of interest. | 05-24-2012 |
20120281895 | MEDICAL IMAGE DIAGNOSTIC APPARATUS AND MEDICAL IMAGE CONTOUR EXTRACTION PROCESSING METHOD - A medical image diagnostic apparatus of the present invention includes: an image display unit that displays a medical image including a target part of an object; an input unit that inputs feature points of the target part; a contour position estimation unit that estimates a contour position of the target part to generate an initial contour; a contour extraction unit that extracts a contour along the shape of the target part using the feature points and the initial contour; and a control unit that displays a composite image, which is obtained by combining the extracted contour and the medical image, on the image display unit. | 11-08-2012 |
20120283567 | ULTRASONIC DIAGNOSTIC APPARATUS AND MEASUREMENT-POINT TRACKING METHOD - An ultrasonic diagnostic apparatus provided with a measurement position setting unit configured to set a region of interest in the cardiac muscle in the ultrasonic image displayed on the display unit, a tracking calculation unit configured to track the movement of the cardiac muscle at a plurality of measurement points in the region of interest, and a physical quantity calculating unit configured to calculate a specific physical quantity on the basis of the results of the tracking. The calculated specific physical quantity is displayed on the display unit. The tracking calculation unit tracks the measurement points using a plurality of first segmenting lines along the epicardium and the endocardium of the cardiac muscle and a plurality of second segmenting lines that are orthogonal to the second segmenting lines. | 11-08-2012 |
20130012835 | ULTRASONIC DIAGNOSTIC APPARATUS AND METHOD FOR RE-INPUTTING MEASUREMENT VALUE OF MEDICAL IMAGE - Disclosed is a medical image diagnostic apparatus which is provided with: a measurement calculation unit configured to calculate measured values by used of multi-dimensional information relating to a target region in the medical image of an object to be examined; an image display unit configured to display the measured values and the medical image; a re-input unit for re-inputting one of the multi-dimensional information and the measured values in the medical image displayed on the image display unit; and a measurement recalculation unit configured to recalculate the other of the multi-dimensional information and the measured values, on the basis of the re-input one of the multi-dimensional information and the measured values. | 01-10-2013 |
20130158399 | ULTRASONIC DIAGNOSTIC APPARATUS AND METHOD OF RETRIEVING AND DISPLAYING HEART FUNCTION TEST PERIOD - The present invention provides an ultrasonic diagnostic apparatus including a bio-signal analyzing section sequentially acquiring a bio-signal from a bio-signal acquiring section over a plurality of cycles to evaluate stability of a heart function in one cycle between particular signal waveforms of the bio-signal and one cycle between particular signal waveforms adjacent to the one cycle between the particular signal waveforms, selecting the one cycle between the particular signal waveforms and one cycle between the particular signal waveforms adjacent to the one cycle between the particular signal waveforms as a test period for the heart function based on the content of the evaluation, and associating the selected test period with a time phase of the bio-signal. | 06-20-2013 |
20140309530 | ULTRASONIC DIAGNOSIS APPARATUS AND METHOD FOR PRESENTING ITEMS FOR INSPECTION - An ultrasonic diagnosis apparatus according to the present invention includes: a storing section storing a plurality of items for inspection including ultrasonic imaging or measurement of an imaged ultrasonogram and an order thereof; a controlling section calculating, regarding an item set for inspection constituted of a next item for inspection which is an item for inspection subsequent to a current item for inspection which is currently being implemented out of the plurality of items for inspection, an implementation frequency at which the item set for inspection is implemented, for each next item for inspection; a displaying section displaying a candidate for the next item for inspection on the basis of the implementation frequency; and an inputting section inputting the next item for inspection from the candidate for the next item for inspection. | 10-16-2014 |