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Chen, Pasadena
Jeannie Chen, Pasadena, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110020237 | Compositions and Methods for Inhibiting Drusen Formation and for Diagnosing or Treating Drusen-Related Disorders - Compositions of matter and methods for inhibiting drusen or drusen-like deposits and/or for treating diseases related to drusen or drusen-like deposits in human or animal subjects by administering to the subject a therapeutically effective amount of i) a conformational epitope of an aggregate that contributes to the formation or biosynthesis of drusen or drusen-like deposits and/or ii) an antibody that binds to a conformational epitope of an aggregate that contributes to the formation or biosynthesis of drusen or the drusen-like deposit. | 01-27-2011 |
Joey Chen, Pasadena, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090222066 | PRINTED CIRCUIT BOARD COMMUNICATION COIL FOR USE IN AN IMPLANTABLE MEDICAL DEVICE SYSTEM - Disclosed is an improved external controller useable in an implantable medical device system. The communication coil in the external controller is formed in a printed circuit board (PCB), i.e., by using the various tracing layers and vias of the PCB. As illustrated, the PCB coil is formed at a plurality of trace layers in the PCB, and comprises a plurality of turns at some or all of the layers. The communication coil may wrap around the other circuitry used in the external controller, which circuitry may be mounted to the front and/or back of the PCB. The geometry of the coil is specially tailored to maximize its inductance, and hence maximize its ability to communicate in the sub-4 MHz range which is not significantly attenuated by the human body. | 09-03-2009 |
Michael M. Chen, Pasadena, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090124515 | METHODS AND COMPOSITIONS FOR PREPARATION OF SELECTIVELY PROTECTED CARBOHYDRATES - The disclosure relates to engineered P450 polypeptides and use of such polypeptides in chemoenzymatic methods to construct selectively protected carbohydrates, which are useful as building blocks for preparation of carbohydrate derivatives and oligosaccharides | 05-14-2009 |
Po-Jui Chen, Pasadena, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100025613 | MICROFLUIDIC VALVE HAVING FREE-FLOATING MEMBER AND METHOD OF FABRICATION - Micro check valves having a free-floating member for controlling flow of fluid in microfluidic and biomedical applications and methods of fabrication. A micro check valve includes a valve seat, a valve cap that contacts the valve seat and an untethered floating member that can move between the valve seat and the valve cap. Certain micro check valves have zero cracking pressure and no reverse leakage. Certain other valves may be configured to permit flow of fluid within a pressure range. The floating member can be solid or define an orifice, and the valve seat can have one or two levels. Valves can be configured to allow fluid to flow when the floating member is pushed by fluid against the valve cap or against the valve seat. The valve seat may be silicon or another material that is compatible with micromachining processes, and the valve cap and the floating member may be a polymer such as Parylene. | 02-04-2010 |
| 20100294041 | MICROFABRICATED IMPLANTABLE WIRELESS PRESSURE SENSOR FOR USE IN BIOMEDICAL APPLICATIONS AND PRESSURE MEASUREMENT AND SENSOR IMPLANTATION METHODS - A variable capacitor, a microfabricated implantable pressure sensor including a variable capacitor and an inductor, and related pressure measurement and implantation methods. The inductor may have a fixed or variable inductance. A variable capacitor and pressure sensors include a flexible member that is disposed on a substrate and defines a chamber. Capacitor elements extend indirectly from the flexible member. Sufficient fluidic pressure applied to an exterior surface of the flexible member causes the flexible member to move or deform, thus causing the capacitance and/or inductance to change. Resulting changes in resonant frequency or impedance can be detected to determine pressure, e.g., intraocular pressure. | 11-25-2010 |
| 20100305550 | MEMS DEVICE AND METHOD FOR DELIVERY OF THERAPEUTIC AGENTS - Embodiments of an implantable device for delivering a therapeutic agent to a patient include a reservoir configured to contain a liquid comprising the therapeutic agent, and a cannula in fluid communication with the reservoir. The cannula is shaped to facilitate insertion thereof into a patient's eyeball. | 12-02-2010 |
| 20110144617 | MEMS DEVICE AND METHOD FOR DELIVERY OF THERAPEUTIC AGENTS - Embodiments of an implantable device for delivering a therapeutic agent to a patient include a reservoir configured to contain a liquid comprising the therapeutic agent, a cannula in fluid communication with the reservoir, and means for forcing fluid from the reservoir into the cannula. Circuitry for controlling the means for forcing fluid from the reservoir into the cannula may be included. | 06-16-2011 |
| 20110144619 | MEMS DEVICE AND METHOD FOR DELIVERY OF THERAPEUTIC AGENTS - Embodiments of an implantable device for delivering a therapeutic agent to a patient include a reservoir configured to contain a liquid comprising the therapeutic agent, and a cannula in fluid communication with the reservoir. A valve for maintaining a constant flow rate through the cannula independent of the pressure applied to the device may be included. | 06-16-2011 |
Si-Yi Chen, Pasadena, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100255023 | DENDRITIC CELL VACCINE COMPOSITIONS AND USES OF SAME - The present invention provides adjuvants, vaccines and therapies in which antigen presentation is enhanced through inhibition of negative immune regulators. The compositions and methods are useful for generating immune responses against antigens, including microbial pathogens and tumor-associated antigens, by way of inhibiting a negative immune regulator in a cell and providing a proinflammatory stimulus. In particular, nucleotides encoding inhibitors of negative immune regulators, antigens, and co-stimulatory molecules are contacted with immune cells in order to elicit a therapeutic or prophylactic response. | 10-07-2010 |
Thomas Y. Chen, Pasadena, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090204885 | AUTOMATED MANAGEMENT AND PUBLICATION OF ELECTRONIC CONTENT FROM MOBILE NODES - A content collection and distribution system operates to collect digital data from a client node, and automatically distributes the collected data to predetermined destinations according to parameters designated in advance by authorized clients and/or other users. A mobile application is configured to operate on mobile handsets of a wireless telephone network, which comprise client nodes. A host curator application is configured to automatically classify incoming data from client nodes, re-formats the data as needed into the least common denominator format and pushes each data portion to a destination configured in advance for that data. A distribution host for data reception applets may be provided; the applets are configured to receive data from the curator application and manage the data for user access in a defined environment. | 08-13-2009 |
Yandong Chen, Pasadena, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090302359 | Anti-blooming protection of pixels in a pixel array for multiple scaling modes - Circuits and methods of generating control signals for transistors in a pixel row of a pixel array are disclosed. The circuits include a transfer transistor control signal row driver that includes a plurality of output branches and a reset transistor control signal row driver that includes a plurality of output branches. The row drivers output positive boosted control signals to selected pixel rows during a photosensor-to-floating diffusion region charge transfer phase and during a floating diffusion region reset phase and to unselected pixel rows during an initial part of an integration phase. The row drivers output positive non-boosted control signals to unselected non-integrating pixel rows. | 12-10-2009 |
| 20100110254 | VLN BIASING SCHEME TO ACHIEVE LOW VERTICAL SHADING FOR HIGH-SPEED AND LARGE-FORMAT CMOS IMAGE SENSORS WITH TOP/BOTTOM READOUT SCHEME - A VLN biasing scheme implemented in an image sensor with top/bottom readout. A first and second current sink coupled to the top of a first column of pixels and a second column of pixels respectively. A third and fourth current sink coupled to the bottom of a first column of pixels and a second column of pixels respectively. During column readout, each current sink sinks an equal amount of current. | 05-06-2010 |
| 20100225243 | METHOD AND SYSTEM FOR CONTROLLING POWER TO PIXELS IN AN IMAGER - A system for controlling power applied to pixels in an imager. A first switch coupling the internal power node of the pixels to the power supply of the imager. A second switch coupling the internal power node of the pixels to a ground potential or low potential. The first and second switches are controlled complimentary to each other during integration and readout of the pixels. A third switch providing a high impedance mode where the internal power node and n+ guard ring are isolated from the operating and ground potentials. | 09-09-2010 |
Yvonne Y. Chen, Pasadena, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100226901 | GENETIC CONTROL OF MAMMALIAN CELLS WITH SYNTHETIC RNA REGULATORY SYSTEMS - The present application relates to nucleic acids that encode a RNA switch responsive to a ligand that can control the expression of a gene product that affects the cell fate determination of a mammalian cell are provided. In some embodiments, the system can be used to control the proliferation or activation of mammalian cells in response to a ligand that can be provided exogenously to the mammalian cell or can be produced by the mammalian cell. The system can be used to promote the growth or proliferation of human T cells in response to an exogenous ligand applied to the cells. In one embodiment, the system detects the ligand through a RNA aptamer that modulates expression of a gene product through activation or inactivation of a ribozyme that modulates expression of the gene product. | 09-09-2010 |