Inventors list

Assignees list

Classification tree browser

Top 100 Inventors

Top 100 Assignees

Chen, NC

Benson K. Chen, Durham, NC US

Patent application number	Description	Published
20090063539	XCAP and SIP Filter Chain State Transforms Via Dynamic Helper Functions for Internet Multimedia Subsystems - The present invention extends a servlet filter chain model to include the ability to dynamically define helper functions. These dynamic helper functions modify the state of an XCAP or SIP request or response as it transitions through the filter chain. The dynamic helper functions are defined via descriptor files that are based on the document type. Each filter in the filter chain has the ability to reference and invoke the helper functions to modify the state of the request and/or response.	03-05-2009
20090265355	SYSTEMS, METHODS AND COMPUTER PROGRAM PRODUCTS FOR AUTOMATIC NETWORK-BASED PERSISTENT XML STORAGE AND MANAGEMENT - Systems, methods and computer program products for automatic network-based persistent XML storage and management. Exemplary embodiments include a method including loading an XDM widget having internal XML, sending an XCAP GET request via an XCAP URI parameter, retrieving an existing XML document at a location associated with the XCAP URI parameter, invoking an initializer callback function via the XDM widget to populate the internal XML with default values associated with an etag, wherein the etag is null, sending an XCAP PUT request via the XCAP URI to store the existing XML document, executing etag header scenarios, providing XML management functions to automatically publish changes to the server, and trigger a timer function to poll for updates from the server and display the resulting updates to the user's screen via a render callback function.	10-22-2009
20100153485	SHARING OF SUBSCRIPTIONS TO RESOURCE LIST CONTENT IN RESOURCE LIST SERVER - A method for sharing subscriptions to the content of a resource list includes creating a first subscription to the content of the resource list upon receipt of a first subscription request for the presence state of the list from a first user; receiving a second presence subscription request for the resource list from a second user; sending a one-time request with the identity of the second subscribing user to an XCAP server; receiving an authorization response related to the one-time request; and creating a super user subscription to the content of the resource list, the super user subscription used to provide presence state information about the list members to the first user and the second user.	06-17-2010
20110161798	MATCHING VARIOUS COMBINATIONS OF XPATH URIS TO THE SAME XML NODE - Embodiments of the present invention address deficiencies of the art in respect to subscribing and updating nodes within XML documents and provide a novel and non-obvious method, system and computer program product for matching various combinations of XML Path Language (XPATH) Uniform Resource Identifiers (URIs). In one embodiment of the invention, a method for matching various combinations of XML Path Language (XPATH) Uniform Resource Identifiers (URIs) that includes receiving a XPATH expression for a node in an XML document, retrieving the node identified by the XPATH expression, determining if a template exists for the identified node, where the template resides in a database of a document management system, comparing the template expression to the XPATH expression and determining if the expressions match. The method can further include modifying the XPATH expression to account for a dominant attribute required by the template when the XPATH expression does not match the template expression and returning the modified XPATH expression.	06-30-2011

Benson Kwuan-Yi Chen, Durham, NC US

Patent application number	Description	Published
20090100289	Method and System for Handling Failover in a Distributed Environment that Uses Session Affinity - In response to detecting a failed server, subscription message processing of a failover server is stopped. A subscription queue of the failed server is opened. A marker message is published to all subscribers of a particular messaging topic. The marker message includes an identification of the failover server managing the subscription queue of the failed server. Messages within the subscription queue of the failed server are processed. In response to determining that a message in the subscription queue of the failed server is the marker message, the subscription queue of the failed server is closed. Then, the failover server resumes processing of its original subscription queue looking for the marker message, while processing yet unseen messages from the queue. Once the marker message is found in the original subscription queue, normal operation is resumed.	04-16-2009
20100063995	Synchronizing Network Feeds in High-Frequency Network Events - A cache server receives a request from a client that includes a requesting entity tag. In turn, the cache server extracts a starting identifier and an ending identifier from the requesting entity tag. The starting identifier is associated with a starting entry and the ending identifier is associated with an ending entry. Next, the cache server determines whether a subsequent entity tag exists that includes a subsequent starting identifier that matches the requesting entity tag's ending identifier. When the cache server identifies a subsequent entity tag, the cache server sends the subsequent entity tag and one or more update entries corresponding to the subsequent entity tag to the client.	03-11-2010

Chang Chen, Huntersville, NC US

Patent application number	Description	Published
20100129949	INCREASING SOLAR CELL EFFICIENCY WITH SILVER NANOWIRES - A method for improving the performance and efficiency of a solar cell comprising the steps of: providing a plurality of silver nanowires and depositing a layer of the silver nanowires onto an emitter surface of the solar cell.	05-27-2010

Cheng-Chung Chen, Raleigh, NC US

Patent application number	Description	Published
20100193950	WAFER LEVEL, CHIP SCALE SEMICONDUCTOR DEVICE PACKAGING COMPOSITIONS, AND METHODS RELATING THERETO - The invention relates generally to wafer level, chip scale semiconductor device packaging compositions capable of providing high density, small scale circuitry lines without the use of photolithography. The wafer level package comprises a stress buffer layer containing a polymer binder and a spinel crystal filler in both a non-activated and a laser activated form. The stress buffer layer is patterned with a laser to thereby activate the filler, and the laser ablation path can then be selectively metalized.	08-05-2010

Chi-Chin Chen, Wilmington, NC US

Patent application number	Description	Published
20090162589	POLYESTER COMPOSITIONS HAVING REDUCED GAS PERMEATION AND METHODS FOR THEIR PRODUCTION - A polyethylene terephthalate and/or co-polyester composition containing one or more bisphenols. A method of making the composition, PET bottle preforms produced from the composition, a method of making a bottle by stretch-blow molding the composition and/or a preform thereof, bottles made from the composition, and a method of reducing the ingress and egress of gases through a film made from the composition.	06-25-2009

Chin Ho Chen, Chapel Hill, NC US

Patent application number	Description	Published
20110152229	BETULINIC ACID DERIVATIVES AS ANTI-HIV AGENTS - The present invention provides compounds of the general structure:	06-23-2011
20110275146	FUSION PROTEINS COMPRISING DP-178 AND OTHER VIRAL FUSION INHIBITOR PEPTIDES USEFUL FOR TREATING AIDS - The present invention relates to fusion peptides which exhibit potent anti-retroviral activity. The fusion peptides of the invention comprise a macromolecular carrier group fused to a gp41-derived DP178 (SEQ ID NO:1) peptide corresponding to amino acids 638 to 673 of the HIV-1	11-10-2011

Chi-Yu Roy Chen, Raleigh, NC US

Patent application number	Description	Published
20110033436	STABLE AQUEOUS SPORE-CONTAINING FORMULATION - Stable aqueous spore-containing chemical formulations having a low to medium viscosity profile are provided. The formulations comprise at least one spore in a mixture of water and at least one water miscible solvent, optionally at least one surfactant, optionally at least one stabilizer such as a metal salt, optionally at least one biocide, optionally at least one buffer, and optionally at least one chemical insecticide or fungicide or a mixture thereof. The formulations are particularly suitable as a seed coating and foliar spray. Methods of preparation as well as methods of treating a plant are also provided.	02-10-2011
20110110906	Combinations of biological control agents and insecticides or fungicides - Compositions are provided that improve overall plant vigor and yield by combining agriculturally effective amounts of at least one environmentally friendly biological control agent and at least one insect control agent and or fungicide. A composition of the present invention is particularly effective in the presence of plant parasitic nematode and fungal species. Along with a benefit of reducing insect pressure, the inventive composition enhances the root system of a plant and improves the establishment of the biological control agent within the rhizosphere, thereby enhancing the effectiveness thereof. Use of a composition of the present invention leads to an overall reduction in crop losses caused by either plant parasitic nematodes or fungi and this reduction is much greater than would have been expected from application of either component alone. Methods for utilizing compositions of the present invention are also provided. Further the compositions according to this invention display synergistic insecticidal, nematicidal, acaricidal or fungicidal activity.	05-12-2011

Chuan-Hua Chen, Cary, NC US

Patent application number	Description	Published
20120012804	THERMAL DIODE DEVICE AND METHODS - A thermal diode comprising a superlyophobic surface, and a lyophilic surface separated from the superlyophobic surface defining a chamber. A liquid is disposed in the chamber, the liquid capable of phase changing during operation of the thermal diode. Methods of cooling and insulating bodies and rectifying heat transfer using the thermal diode.	01-19-2012

Chuan-Hua Chen, Durham, NC US

Patent application number	Description	Published
20080210559	High energy density electro-osmotic pump and actuator - An electro-osmotic pump includes a pump chamber having a wall fabricated of an electric double layer material, the surface area of the electric double layer material being high relative to the volume of the chamber. An electric potential applied across the material causes a fluid in the chamber to be transported through the wall.	09-04-2008

Daitao Chen, Durham, NC US

Patent application number	Description	Published
20090291917	Boron-Containing Small Molecules as Anti-Inflammatory Agents - Compounds and methods of treating anti-inflammatory conditions are disclosed.	11-26-2009

Daitao Chen, Raleigh, NC US

Patent application number	Description	Published
20110190235	BORON-CONTAINING SMALL MOLECULES AS ANTIPROTOZOAL AGENTS - This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.	08-04-2011
20110207702	BORON-CONTAINING SMALL MOLECULES AS ANTI-PROTOZOAL AGENTS - This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.	08-25-2011

David D. Chen, Cary, NC US

Patent application number	Description	Published
20090187594	Method and System for Creation and Reuse of Concise Business Schemas Using a Canonical Library - An exemplary feature is a method for using XML Schema based standards. The method consists of constructing a reduced schema for a specific interaction from a collection of reusable artifacts. The method further consists of publishing the reduced schema in a repository thereby allowing the reduced schema to be reused.	07-23-2009
20100088326	Service oriented architecture aggregation - A method, system and computer program product for identifying one or more niche services to combine into a common service, wherein the niche service is a part of a service oriented architecture (SOA). The extensible markup language (XML) schema of the one or more niche services is aggregated into a combined XML schema, wherein the combined XML schema is the XML schema of the common service. A web services description language (WSDL) of the one or more niche services are aggregated to establish a combined WSDL, wherein the combined WSDL is the WSDL of the common service. The common service is generated from the combined XML schema and the combined WSDL. The combined WSDL, utilized to identify the combined service, comprises a service provider URL, one or more service operations, and combined XML schema. The combined XML schema is associated with a common service request and a common service response. When the XML schema of the niche service is not equal with the combined XML schema, mediation is invoked.	04-08-2010

David De-Hui Chen, Cary, NC US

Patent application number	Description	Published
20090172395	System and Method for Service Virtualization Using a MQ Proxy Network - A system, method, and computer program product for transmitting message traffic encapsulating a MQ network having a plurality of MQ clients coupled to a MQ queue via at least one MQ queue manager and at least one MQ proxy server coupled to the plurality of MQ clients. The at least one MQ proxy server retrieves a message from a first MQ client coupled thereto, evaluates the message content and forwards the message to the MQ queue via a designated MQ queue manager. If the destination MQ client is served by a second MQ proxy server the originating MQ proxy server notifies the second MQ proxy server coupled to the second MQ client. The second MQ proxy server retrieves the message from the MQ queue thru the designated MQ queue manager, evaluates the message content and forwards the message to the second MQ client. If the first MQ client and the second or destination MQ client are served by the same MQ proxy server, then the MQ proxy server will just retrieve the message from the MQ queue through the designated MQ queue manager and forward the message to the second MQ client.	07-02-2009

Dayong Chen, Cary, NC US

Patent application number	Description	Published
20080279182	Method and Apparatus for the Use of Network Coding in a Wireless Communication Network - According to a method and apparatus taught herein, a network node includes a receiver circuit that determines soft values for received packets corresponding to the information bit groups associated with network coding operations, where the soft values are determined for each information bit group based on joint probabilities of the information bits within the information bit group. For example, first soft values are determined for the information bit groups in a first (received) constituent packet and second soft values are likewise determined for the information bit groups in a network-coded (received) packet that depends on the first constituent packet and a second constituent packet. Third soft values are generated for the information bit groups of the second constituent packet based on jointly evaluating the first and second soft values.	11-13-2008
20080282125	Method and Apparatus for Combined Packet Retransmission and Soft Decoding of Combined Packets in a Wireless Communication Network - In a wireless communication network using point-to-point or point-to-multipoint communications, this disclosure teaches the use of combined packets for retransmission and corresponding soft value processing at a receiver, wherein combined packets are formed as the logical combination of two or more previously transmitted packets and allow the receiver to use a single combined packet to correct one or more failed packets. For example, with the combined packet retransmission and corresponding soft value receiver processing as taught herein, a given receiver can use a given combined packet to correct bit errors in all (failed) packets comprising the combined packet as long as the bit errors in a failed packet do not overlap (or align) with bit errors in the other failed packets comprising the combined packet.	11-13-2008
20100266071	METHOD AND APPARATUS FOR GENERATING SOFT BIT VALUES IN REDUCED-STATE EQUALIZERS - A demodulator is provided that functions as a reduced-state equalizer and produces reliable soft bit values. According to an embodiment, soft bit values are generated for a sequence of transmitted symbols using a demodulator by updating an M-state trellis managed by the demodulator responsive to a transition from symbol time n−1 to symbol time n, where M is a function of the number of bits per symbol in the sequence of transmitted symbols. Survivor metrics associated with the M states of the trellis are saved each symbol time so that the demodulator can calculate soft bit values with regard to transitions from symbol time n+D−1 to symbol time n+D. The survivor metrics indicate the probability that each respective state represents the transmitted symbol associated with symbol time n+D−1. The trellis is traced back through to calculate soft bit values for a symbol detected at symbol time n−D based on survivor metrics saved for the M states at symbol time n−D.	10-21-2010
20100279701	INTEGRATED POWER CONTROL AND LINK ADAPTATION - A method and apparatus in a base station for jointly controlling sub-channel transmission power and assigned codec modes for a first and second mobile station utilizing Voice services over Adaptive Multi-user channel on One Slot (VAMOS). The base station receives signal quality information reports from the mobile stations every 480 ms using the Slow Associated Control Channel (SACCH), and receives codec mode requests from the mobile stations every 40 ms using Adaptive Multi-Rate (AMR) in-band signaling. The base station associates the requested codec modes with estimated levels of speech quality currently being experienced by the first and second mobile stations. The base station then allocates sub-channel transmission power and assigns codec modes to the first and second mobile stations based on the estimated levels of speech quality associated with the requested codec modes and the signal quality reports.	11-04-2010
20110150154	HYBRID CORRELATION AND LEAST SQUARES CHANNEL ESTIMATION - A hybrid channel estimator for a wireless communication system receiver includes both correlation based and least squares based channel estimators. The correlation estimator is used when signal quality is low or noise is colored. The least squares estimator is used when signal quality is high or noise is white. An interference suppression filter improves signal quality by suppressing interference in a received signal. Generally, correlation channel estimation is performed initially, when signal quality is low and noise is colored, and interference suppression filtering is performed to increase signal quality by removing certain portion of interference and whitening the overall impairment spectrum. These may be done iteratively. When the signal quality improves, least squares channel estimation is performed, which may also be iterative. The training sequence and noise may be whitened prior to performing least squares channel estimation, which is the final operation before channel estimates are forwarded to a demodulator.	06-23-2011

Enn-Ling Chen, Chapel Hill, NC US

Patent application number	Description	Published
20100219829	LONG T1 ARTIFACT SUPPRESSION TECHNIQUES FOR MAGNETIC RESONANCE IMAGING - A method of suppressing artifacts arising from tissue, fluids, or other long-T1 species when acquiring magnetic resonance data with a segmented pulse sequence that assumes that magnetization is at steady state, said method including suppressing artifacts by producing an artifact suppression module (ASM) before the segmented sequence, the artifact suppression module comprising at least one selective, non-selective, or volume-selective suppression pulse and a time delay.	09-02-2010

Eric Chen, Chapel Hill, NC US

Patent application number	Description	Published
20090265809	Modified Cry3A Toxins and Nucleic Acid Sequences Coding Therefor - Methods for making a modified Cry3A toxin are disclosed. Such methods include the insertion of a protease recognition site that is recognized by a gut protease of a target insect, such as corn rootworm, into at least one position of a Cry3A toxin so that a modified Cry3A toxin is thus designed. The coding sequence of the modified Cry3A toxin may be transformed into a host cell and the host cell grown under conditions that allow the host cell to produce the modified Cry3A toxin. The host cell may be a plant cell and the plant may be comprised in a transgenic plant. Thus, the transgenic plant may be used to produce the modified Cry3A toxin.	10-22-2009
20110288272	MODIFIED CRY3A TOXINS AND NUCLEIC ACID SEQUENCES CODING THEREFOR - Methods for making a modified Cry3A toxin are disclosed. Such methods include the insertion of a protease recognition site that is recognized by a gut protease of a target insect, such as corn rootworm, into at least one position of a Cry3A toxin so that a modified Cry3A toxin is thus designed. The coding sequence of the modified Cry3A toxin may be transformed into a host cell and the host cell grown under conditions that allow the host cell to produce the modified Cry3A toxin. The host cell may be a plant cell and the plant may be comprised in a transgenic plant. Thus, the transgenic plant may be used to produce the modified Cry3A toxin.	11-24-2011
20110289627	MODIFIED CRY3A TOXINS AND NUCLEIC ACID SEQUENCES CODING THEREFOR - Methods for making a modified Cry3A toxin are disclosed. Such methods include the insertion of a protease recognition site that is recognized by a gut protease of a target insect, such as corn rootworm, into at least one position of a Cry3A toxin so that a modified Cry3A toxin is thus designed. The coding sequence of the modified Cry3A toxin may be transformed into a host cell and the host cell grown under conditions that allow the host cell to produce the modified Cry3A toxin. The host cell may be a plant cell and the plant may be comprised in a transgenic plant. Thus, the transgenic plant may be used to produce the modified Cry3A toxin.	11-24-2011

Feng-Wei Chen, Research Triangle Park, NC US

Patent application number	Description	Published
20120005280	MESSAGE THREAD MANAGEMENT USING DYNAMIC POINTERS - Embodiments of the present invention provide a method, system and computer program product for message thread management using dynamic pointers. In an embodiment of the invention, a method for message thread management using dynamic pointers is provided. The method includes selecting a message thread in a message inbox of a messaging client, comparing characteristics of the message thread to a pre-established set of criteria, and removing the selected message thread to remote storage, generating a message thread pointer to the selected message thread and inserting the message thread pointer into the message inbox in place of the selected message thread in response to the characteristics of the message thread satisfying the criteria.	01-05-2012

Feng-Wei Chen, Cary, NC US

Patent application number	Description	Published
20090327189	DYNAMIC ONTOLOGY-DRIVEN TEMPLATE SELECTION - One aspect of the present invention includes dynamically selecting templates through the use of an ontology. In one embodiment, an ontology is defined to structure information system content, and an ontology classification is then assigned when content is provided to the information system. Based on this classification, the most appropriate template classified in the ontology is applied to the content. If a template exists at the content item's ontology level, this template is applied to the content. If no template exists, then the ontology tree is navigated upward to locate a template at the nearest ancestor ontology level. If a template was found by navigating the ontology tree, then this template is applied to the content item.	12-31-2009
20090327337	DYNAMIC ONTOLOGY-DRIVEN TEMPLATE SELECTION - One aspect of the present invention includes dynamically selecting templates through the use of an ontology. In one embodiment, an ontology is defined to structure information system content, and an ontology classification is then assigned when content is provided to the information system. Based on this classification, the most appropriate template classified in the ontology is applied to the content. If a template exists at the content item's ontology level, this template is applied to the content. If no template exists, then the ontology tree is navigated upward to locate a template at the nearest ancestor ontology level. If a template was found by navigating the ontology tree, then this template is applied to the content item.	12-31-2009
20100030552	DERIVING ONTOLOGY BASED ON LINGUISTICS AND COMMUNITY TAG CLOUDS - In some embodiments, a method comprises receiving a tag cloud including tags that hyperlink to web content. The method can also comprise separating the tags into different linguistic categories, assigning a weight to each tag, and grouping the tags into clusters, wherein tags in a cluster are associated with a context. The method can also include determining one or more domains for the tag clusters, wherein a domain is a broadest class that defines one or more of the tags in a linguistic category, determining a hierarchy for the tags based on the weights of the tags, and identifying linguistic relationships between the tags. The method can also comprise determining properties associated with one or more of the tags and one or more of the domains, wherein the tag's properties are determined using linguistic analysis and storing the tags, the hierarchies, the linguistic relationships, and the properties.	02-04-2010
20100114886	RELEVANCE CONTENT SEARCHING FOR KNOWLEDGE BASES - Embodiments of the present invention provide a novel and non-obvious method, server and computer program product for finding relevant content in a knowledge base. A method for finding items that are related to a user selected item in a knowledge base is provided. The method can include generating a first list of knowledge base items with a defined relationship to the user selected item and generating a second list of knowledge base items that belong to the same category as a category of the user selected item. The method can further include generating a third list of knowledge base items having one or more tags identical to one or more tags of the user selected item and selecting a first set of knowledge base items that are present in the first, second or third lists. The method can further include displaying the first set of knowledge base items as most relevant.	05-06-2010
20110010341	SYSTEM, METHOD, AND APPARATUS FOR REPLICATING A PORTION OF A CONTENT REPOSITORY - A computer-implemented method for selecting a portion of a content repository for replication including receiving an input describing one or more desired relationship patterns for replication, generating a query for the desired relationship patterns, identifying content items of a content repository matching the desired relationship patterns, and selecting the identified content items of the content repository. The input is received at a graphical user interface (GUI). The GUI operates on a computer. The relationship patterns are associated with an ontology describing relationships between content items in a content repository. The content repository includes a plurality of content items.	01-13-2011
20110010342	SYSTEM, METHOD, AND APPARATUS FOR REPLICATING A PORTION OF A CONTENT REPOSITORY USING BEHAVIORAL PATTERNS - A computer-implemented method for selecting a portion of a content repository for replication including monitoring a usage pattern of a content repository, determining one or more preferred relationship patterns for replication in response to the usage pattern, identifying content items of the content repository matching the preferred relationship patterns, and selecting the identified content items of the content repository. Monitoring the usage pattern is performed by a pattern recognition engine operating on a computer. The content repository includes two or more content items. The relationship patterns are associated with an ontology describing relationships between content items in the content repository.	01-13-2011
20110161070	PRE-HIGHLIGHTING TEXT IN A SEMANTIC HIGHLIGHTING SYSTEM - A method, computer system and/or computer program product pre-highlight text that is located in a search. A text highlight and a triple statement semantic annotation based on the text highlight of a first document are received. The triple statement semantic annotation comprises a subject, a relationship and an object. A natural language processing (NLP) pattern based on the triple statement semantic annotation is generated. The NLP pattern is representative of a linguistic pattern between the text highlight and the triple statement semantic annotation. A multi-dimensional linguistic profile is generated based on the text highlight, the triple statement semantic annotation and the NLP pattern, wherein the multi-dimensional linguistic profile defines entities, relationships and attributes associated with document text. Text in a second document is compared with the multi-dimensional linguistic profile, and text in the second document is highlighted based on the comparison.	06-30-2011
20110307562	RECOMMENDATION ENGINE FOR EVENT ANALYZER WITH INTEGRATED INFORMATION - A computer implemented method manages responses to electronic messages. A computer detects a receipt of an electronic message by a recipient. The computer generates a summary of a content of the electronic message. The summary describes a need for a meeting between the recipient and an other party. The computer generates a recommendation for a communication channel for the meeting between the recipient and the other party.	12-15-2011
20120002798	MANAGING PARTICIPATION IN A TELECONFERENCE - A computer implemented method manages participation in a teleconference. Teleconference inputs from participants of a teleconference are monitored for use of an unrelated term, which is a term that has been deemed unrelated to a topic of the teleconference. Upon determining that an errant participant is using the unrelated term in at least one of the teleconference inputs, an alert is generated to prompt the errant participant to limit future teleconference inputs to the topic of the teleconference.	01-05-2012
20120005195	CREATING AN ONTOLOGY USING AN ONLINE ENCYCLOPEDIA AND TAG CLOUD - A method for generating an ontology may include selecting, by a processing device, a tag in a tag cloud. The method may also include searching, by the processing device, an online encyclopedia for content corresponding to the selected tag and determining, by the processing device, at least one category to which the content belongs in the online encyclopedia in response to finding the content corresponding to the selected tag in the online encyclopedia. The method may additionally include adding, by the processing device, a class to the ontology corresponding to the at least one category of the content in the online encyclopedia.	01-05-2012

Frank Chen, Greensboro, NC US

Patent application number	Description	Published
20110117292	METHODS FOR CONTROLLING COATING GLOSS - A method including applying a coating composition on a substrate to form a coating, wherein the coating has a first surface roughness; transferring a pattern to the coating to form a patterned coating, wherein the patterned coating has a second surface roughness different from the first surface roughness; and curing the patterned coating to form a cured coating with a desired level of gloss.	05-19-2011
20110139359	IN-PRESS PROCESS FOR COATING COMPOSITE SUBSTRATES - An improved process for manufacture of polymer coated composite substrates is described. a coated composite substrate is prepared in the press by applying a layer of a primer coating composition to the surface of a compressible mat comprising fibers and/or particles and a resin binder. The primer coating composition is formulated preferably as a fast setting polymer latex capable of forming a chemically crosslinked polymer matrix when applied to the surface of a compressible mat. a thermosetting top coat composition can be applied directly over the wet primer coating composition before heat-processing the mat to improve surface quality and release characteristics. Compressing and heating the coated mat produces a primed composite substrate directly out of the press.	06-16-2011

Frank B. Chen, Greensboro, NC US

Patent application number	Description	Published
20080245395	Antimicrobial compositions and methods - Antimicrobial compositions and methods eradicate and remove fungi and bacteria from indoor and outdoor structures and materials including porous substrates. The antimicrobial compositions can be made from gel precursors, utilized in gel states and adjusted to reduce the viscosity for applications where low viscosity is advantageous. The antimicrobial compositions applied to a surface can be wiped and rinsed to remove the antimicrobial composition and organic residue.	10-09-2008

Frank Bor-Her Chen, Greensboro, NC US

Patent application number	Description	Published
20090004479	CHECK-RESISTANT COATED VENEERED ARTICLE - A coated veneered article has at least one visible wood veneer layer coated with a multilayer finishing system comprising a coating layer nearest the veneer layer comprising a cationically polymerized moiety or moiety polymerized via cationic and free radical cure mechanisms, and an outermost coating layer comprising a free radically polymerized moiety. The article exhibits less veneer checking than a veneered article coated only with free radically polymerized coating layers.	01-01-2009

Gong Chen, Clemmons, NC US

Patent application number	Description	Published
20120037175	MELTABLE SMOKELESS TOBACCO COMPOSITION - A meltable smokeless tobacco composition configured for insertion into the mouth of a user is provided. The smokeless tobacco composition includes a particulate tobacco material and a lipid having a melting point of about 36° C. to about 45° C. An associated process is also provided. The process includes melting a lipid having a melting point of about 36° C. to about 45° C. to form a molten lipid composition, mixing a particulate tobacco material with the molten lipid composition to form a molten smokeless tobacco composition slurry, and cooling the molten smokeless tobacco composition slurry to form a solidified smokeless tobacco composition.	02-16-2012
20120060854	THERMAL TREATMENT PROCESS FOR TOBACCO MATERIALS - A method of thermally processing a tobacco material is provided, the method including the steps of (i) mixing a tobacco material, water, and an additive selected from the group consisting of lysine, glycine, histidine, alanine, methionine, glutamic acid, aspartic acid, proline, phenylalanine, valine, arginine, di- and trivalent cations, asparaginase, saccharides, phenolic compounds, reducing agents, compounds having a free thiol group, oxidizing agents, oxidation catalysts, plant extracts, and combinations thereof, to form a moist tobacco mixture; (ii) heating the moist tobacco mixture at a temperature of at least about 60° C. to form a heat-treated tobacco mixture; and (iii) incorporating the heat-treated tobacco mixture into a tobacco product. Heat-treated tobacco composition prepared according to the method are also provided, such as heat-treated smokeless tobacco composition comprising a tobacco material, water, flavorant, binder, and filler, the heat-treated smokeless tobacco composition having an acrylamide content of less than about 2000 ppb.	03-15-2012

Gong Chen, Winston-Salem, NC US

Patent application number	Description	Published
20100300463	THERMAL TREATMENT PROCESS FOR TOBACCO MATERIALS - A method of thermally processing a tobacco material is provided, the method including the steps of (i) mixing a tobacco material, water, and an additive selected from the group consisting of lysine, glycine, histidine, alanine, methionine, glutamic acid, aspartic acid, proline, phenylalanine, valine, arginine, di- and trivalent cations, asparaginase, saccharides, phenolic compounds, reducing agents, compounds having a free thiol group, oxidizing agents, oxidation catalysts, plant extracts, and combinations thereof, to form a moist tobacco mixture; (ii) heating the moist tobacco mixture at a temperature of at least about 60° C. to form a heat-treated tobacco mixture; and (iii) incorporating the heat-treated tobacco mixture into a tobacco product. Heat-treated tobacco composition prepared according to the method are also provided, such as heat-treated smokeless tobacco composition comprising a tobacco material, water, flavorant, binder, and filler, the heat-treated smokeless tobacco composition having an acrylamide content of less than about 2000 ppb.	12-02-2010
20110048434	THERMAL TREATMENT PROCESS FOR TOBACCO MATERIALS - A method of preparing a tobacco material for use in a smoking article is provided, including (i) mixing a tobacco material, water, and an additive selected from the group consisting of lysine, glycine, histidine, alanine, methionine, glutamic acid, aspartic acid, proline, phenylalanine, valine, arginine, di- and trivalent cations, asparaginase, saccharides, phenolic compounds, reducing agents, compounds having a free thiol group, oxidizing agents, oxidation catalysts, plant extracts, and combinations thereof; (ii) heating the mixture; and (iii) incorporating the heat-treated mixture into a smoking article as a smokable material. A smoking article in the form of a cigarette is also provided that includes a tobacco material pre-treated to inhibit reaction of asparagine to form acrylamide in mainstream smoke. Upon smoking, the smoking article is characterized by an acrylamide content of mainstream smoke that is reduced relative to an untreated control smoking article.	03-03-2011

Jeng S. Chen, Chapel Hill, NC US

Patent application number	Description	Published
20100017914	INSECTICIDAL PROTEINS - Compositions and methods for controlling plant pests are disclosed. In particular, novel engineered hybrid insecticidal proteins (eHIPs) having toxicity to at least corn rootworm are provided. By fusing unique combinations of complete or partial variable regions and conserved blocks of at least two different	01-21-2010

Jeng Shong Chen, Chapel Hill, NC US

Patent application number	Description	Published
20110023194	ENGINEERING ZYMOGEN FOR CONDITIONAL TOXICITY - The ADP-ribosyltransferase, Vip2, exerts its intracellular toxicity in insects by modifying actin and preventing actin polymerization. Due to the nature of this toxin, expression of Vip2 in planta is lethal to the plant. Described herein are methods of making zymogens of toxic proteins that are benign in a non-target organism and are activated in a target organism. Disclosed herein are methods of engineering a random propeptide library at a terminus of a toxic protein and selecting for malfunctional variants in yeast. Using this method a selected proenzyme possesses reduced enzymatic activity as compared to the wild-type Vip2 protein, but remains a potent toxin towards corn rootworm larvae. The Vip2 zymogen can be proteolytically activated by corn rootworm digestive proteases.	01-27-2011

Jianfu Chen, Chapel Hill, NC US

Patent application number	Description	Published
20100292297	Micrornas That Regulate Muscle Cell Proliferation and Differentiation - The presently disclosed subject matter provides methods and compositions for modulating gene expression in myocytes. Also provided are cells comprising the compositions of the presently disclosed subject matter.	11-18-2010

Jyh-Shing Chen, Cary, NC US

Patent application number	Description	Published
20110271062	INTEGRATED STORAGE CONTROLLER AND APPLIANCE METHOD AND SYSTEM - An integrated data center method and system combines a storage controller and one or more appliances onto a computer platform. Storage controller component executes on the hardware of a computer platform and has exclusive access to a first storage controller host bus adapter coupled to a storage shelf having one or more storage devices. The method and system provisions a virtualized instance of the hardware from the computer platform to deliver application services from an appliance component. The appliance component may share the processing resources from the computer platform through multiple different virtual machines. With respect to storage, aspects of the present invention exclusively associates an appliance host bus adapter from the computer platform to the appliance component. In addition, aspects of the present invention also provide control of the appliance host bus adapter to the appliance component passing through the virtualized instance of the hardware. To access the storage devices, the appliance host bus adapter and corresponding appliance component are coupled with a second storage controller host bus adapter associated with the storage controller component. Aspects of the present invention enable the access to the storage controller component and storage devices from each appliance host bus adapter. This enables applications associated with the appliance component to perform storage operations on the storage devices at a high throughput even though the applications are executing within a virtualized instance of the hardware.	11-03-2011

Ke Chen, Cary, NC US

Patent application number	Description	Published
20080242709	2-AMIDO-4-ISOXAZOLYL THIAZOLE COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF - 2-Amido-4-isoxazolyl thiazole compounds exhibiting ATP-utilizing enzyme inhibitory activity, methods of using compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions comprising compounds exhibiting ATP-utilizing enzyme inhibitory activity, are disclosed.	10-02-2008

Ke Chen, Chapel Hill, NC US

Patent application number	Description	Published
20090048313	2-AMIDO-THIAZOLE-BASED COMPOUNDS EXHIBITING ATP-UTILIZING ENZYME INHIBITORY ACTIVITY, AND COMPOSITIONS, AND USES THEREOF - 2-Amido-4-substituted-aryl-thiazole-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, methods of using compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions comprising compounds exhibiting ATP-utilizing enzyme inhibitory activity, are disclosed.	02-19-2009

Kui Chen, Raleigh, NC US

Patent application number	Description	Published
20090081798	Protein S Functional Assay - The invention relates generally to a new functional protein S assay and kit that is based on the ability of endogenous protein S to prolong clotting time. In the assay procedure, a test plasma sample is diluted with protein S deficient plasma, followed by the addition of purified or recombinant tissue factor (pTF or rTF), purified natural or synthetic phospholipid (pPL or sPL) and activated protein C (APC) or protein C activator (PCA). The clotting time is then measured and compared to a standard curve or a normal control.	03-26-2009

Lianzhou Chen, Raleigh, NC US

Patent application number	Description	Published
20110275761	Methods for Making Molding Resins - Methods of making unsaturated polyester compositions are provided and include reacting: (i) plant and animal oil triglycerides, an alkyl ester of a saturated or unsaturated fatty acid or mixtures thereof; (ii) a difunctional, or polyfunctional glycol or mixtures thereof; (iii) a difunctional or polyfunctional acid, their anhydrides or alkyl esters and mixtures thereof; (iv) a strained cycloolefin; (v) a component(s) that function as a compound capable of initiating polymerization at high temperature and which is stable at room temperature; and (vi) low profile additives, fillers and reinforcements.	11-10-2011

Minhan Chen, Cary, NC US

Patent application number	Description	Published
20090146722	Systems and Arrangements to Provide Input Offset Voltage Compensation - In one embodiment a method is disclosed that includes applying a series of voltages to an input of an offset evaluation latch, detecting an offset voltage from the offset evaluation latch in response to the application of the series of voltages, and applying an offset compensation voltage to the input of a plurality of sampling latch in response to the detected offset voltage. In some embodiments a digital value can be assigned to the applied offset voltage. When the offset voltage is determined, it can be applied to a plurality sampling latches and a data stream can be received and clock and data recovery can be performed.	06-11-2009
20120001691	VARIABLE GAIN AMPLIFIER WITH REDUCED POWER CONSUMPTION - A variable gain amplifier includes a first common mode (CM) node configured to receive a first differential signal of a pair of differential signals. A first regulator couples to the first CM node, the first regulator being configured to generate a first CM offset. A second CM node is configured to receive a second differential signal of the pair of differential signals. A second regulator couples to the second CM node, the second regulator being configured to generate a second CM offset. In one embodiment, the first CM offset and the second CM offset together comprise a net CM offset, the net CM offset being configured to replace a current source net offset.	01-05-2012

Pingyun Chen, Durham, NC US

Patent application number	Description	Published
20110152237	Chemical Compounds - Disclosed are compounds of Formula III. Also disclosed are salts of the compounds, pharmaceutical composition comprising the compounds or salts, and methods for treating HCV infection by administration of the compounds or salts.	06-23-2011

Pingyun Chen, Chapel Hill, NC US

Patent application number	Description	Published
20100056795	NOVEL INTERMEDIATE AND PROCESS USEFUL IN THE PREPARATION OF -(2-CHLOROPHENYL)-METHANONE - The present invention relates to novel compounds, (2-chlorophenyl)-[2-(2-hydroxy-2-pyridin-4-yl-vinyl)pyridin-3-yl]methanone benzoate, and (2-chlorophenyl)-[2-(2-hydroxy-2-pyridin-4-yl-vinyl)pyridin-3-yl]methanone toluate, which are useful intermediates for the preparation of the compound of Formula I: (I) The present invention further relates to novel processes for preparing a crystalline compound, which is {2-[1-(3,5-bis-trifluoromethyl-benzyl)-5-pyridin-4-yl-1H-[1,2,3]triazol-4-yl]-pyridin-3-yl}-(2-chlorophenyl)-methanone, Form IV	03-04-2010

Pingyun Y. Chen, Durham, NC US

Patent application number	Description	Published
20100197754	CRYSTALLINE N--5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide hydrochloride - An improved AKT inhibiting compound, crystalline N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide hydrochloride.	08-05-2010
20110288142	CRYSTALLINE N--5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide hydrochloride - An improved AKT inhibiting compound, crystalline N-{(1S)-2-amino-1-[(3-fluorophenyl)methyl]ethyl}-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxamide hydrochloride.	11-24-2011

Qingqi Chen, Chapel Hill, NC US

Patent application number	Description	Published
20090306070	TETRA-O-SUBSTITUTED BUTANE-BRIDGE MODIFIED NDGA DERIVATIVES, THEIR SYNTHESIS AND PHARMACEUTICAL USE - The present invention relates to nordihydroguaiaretic acid derivative compounds, namely, butane bridge modified nordihydroguaiaretic acid (NDGA) compounds and butane bridge modified tetra-O-substituted NDGA compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them and kits including them for the treatment of diseases and disorders, in particular, diseases resulting from or associated with a virus infection, such as HIV infection, HPV infection, or HSV infection, an inflammatory disease, such as various types of arthritis and inflammatory bowel diseases, metabolic diseases, such as diabetes and hypertension, or a proliferative disease, such as diverse types of cancers.	12-10-2009
20100022528	TETRA-SUBSTITUTED NDGA DERIVATIVES VIA ETHER BONDS AND CARBAMATE BONDS AND THEIR SYNTHESIS AND PHARMACEUTICAL USE - Disclosed are nordihydroguaiaretic acid derivative compounds including various end groups bonded by a carbon atom or heteroatom though a side chain bonded to the respective hydroxy residue O groups by an ether bond or a carbamate bond, pharmaceutical compositions, methods of making them, and methods of using them and kits including them for the treatment of diseases and disorders, in particular, diseases resulting from or associated with a virus infection, such as HIV infection, HPV infection, or HSV infection, an inflammatory disease, such as various types of arthritis and inflammatory bowel diseases, a metabolic disease, such as diabetes, a vascular disease, such as hypertension and macular degeneration, or a proliferative disease, such as diverse types of cancers.	01-28-2010
20120029216	SCALABLE SYNTHETIC PROCESS FOR MAKING TERAMEPROCOL - A manufacturing process for making terameprocol (1) which includes the following reaction scheme, wherein a first general reaction is the formation of a furan intermediate (39) and a second general reaction is the ring-reduction and ring-opening of the furan intermediate (39) to form the terameprocol (1):	02-02-2012

Rouying Chen, Apex, NC US

Patent application number	Description	Published
20080263725	PHOSPHATASE STRESS-RELATED PROTEINS AND METHODS OF USE IN PLANTS - A transgenic plant transformed by a phosphatase stress-related protein (PHSRP) coding nucleic acid, wherein expression of the nucleic acid sequence in the plant results in increased tolerance to environmental stress as compared to a wild type variety of the plant. Also provided are agricultural products, including seeds, produced by the transgenic plants. Also provided are isolated PHSRPs, and isolated nucleic acid coding PHSRPs, and vectors and host cells containing the latter.	10-23-2008

Roy C.y. Chen, Raleigh, NC US

Patent application number	Description	Published
20080274890	Method of Producing Suspended Agricultural Chemical Composition - A method of producing a suspended agricultural chemical composition, includes the steps of: grinding an agricultural chemical active ingredient; mixing at least water, a polyalcohol, a mineral salt, and a surfactant to produce a solution; adding to the solution the ground agricultural chemical active ingredient and a suspension stabilizer, to produce a mixture; heating the mixture to 40 to 70° C. while stirring; cooling the heated mixture to 10 to 25° C.; and wet-milling the cooled mixture at 30° C. or below. Alternatively the method includes the steps of: grinding an agricultural chemical active ingredient; mixing at least water, a polyalcohol, a mineral salt, and a surfactant to produce a solution; adding to the solution the ground agricultural chemical active ingredient and a suspension stabilizer to produce a mixture; wet-milling the mixture; heating the wet-milled mixture to 40 to 70° C. while stirring; and cooling the heated mixture.	11-06-2008

Shen-En Chen, Charlotte, NC US

Patent application number	Description	Published
20120033851	SPATIALLY INTEGRATED AERIAL PHOTOGRAPHY FOR BRIDGE, STRUCTURE, AND ENVIRONMENTAL MONITORING - Spatially Integrated Small-Format Aerial Photography (SFAP is one aspect of the present invention. It is a low-cost solution for bridge surface imaging and is proposed as a remote bridge inspection technique to supplement current bridge visual inspection. Providing top-down views, the airplanes flying at about 1000 ft, can allow visualization of sub-inch (large) cracks and joint openings on bridge decks or highway pavements. On board Global Positioning System is used to help geo-reference images collected and allow automated damage detection. A deck condition rating technique based on large crack detection is used to quantify the condition of the existing bridge decks.	02-09-2012

Shih-Fong Chen, Apex, NC US

Patent application number	Description	Published
20090203719	ENHANCING TREATMENT OF MDR CANCER WITH ADENOSINE A3 ANTAGONISTS - The present invention discloses the use of high affinity adenosine A	08-13-2009

Shuang Chen, Greensboro, NC US

Patent application number	Description	Published
20080306878	METHOD AND SYSTEM FOR ADMINISTERING INDEX-LINKED ANNUITY - A method for administering an annuity product comprises the steps of establishing an annuity account, storing data relating to the account, determining an amount of an income payment and paying the income payment to the account owner. The amount of the income payment is subtracted from an account value. The amount of the account value is adjusted by a first process which includes adjusting the account value by a first index. The amount of the income payment is periodically redetermined by a second process which includes adjusting the amount of the income payment by a second index. The first and second processes are separate processes designed to cause the account value and a present value of the income payments to diverge, such that the value of the income payments becomes increasingly greater relative to the account value during a payout phase of the annuity account. One embodiment comprises a computer system for administering the annuity product in accordance with the subject method.	12-11-2008

Ta-Ming Chen, Cary, NC US

Patent application number	Description	Published
20120076002	INTEGRATING MULTIMEDIA CAPABILITIES WITH CIRCUIT-SWITCHED CALLS - The present invention monitors call signaling events stemming from a circuit-switched call between a caller and a called party and controls a packet-session between user agents on respective endpoints associated with the caller and called party. The endpoints may include any type of computational device capable of facilitating the packet-session over a packet-switched network. Control of the user agents may be provided via a proxy for the user agents and may use the session initiation protocol (SIP), or like session control protocol for communications.	03-29-2012

Xing Chen, Lissadell, NC US

Patent application number	Description	Published
20110212664	Inflatable Recreational Device - An inflatable recreational device includes a first member and a plurality of second members, wherein the first member be a cylinder with an inner side and an outer side, and wherein the second members may be attached to the outer side thereof. The second members may form closed air chambers. A user may place him or herself within the first member for protection during use of the device. In another embodiment, a plurality of second members may form a cavity, without needing a first member, to protect the user.	09-01-2011

Xing Chen, Charlotte, NC US

Patent application number	Description	Published
20080282621	Maze Device - Disclosed is a multi-modular maze device comprising a plurality of maze modules interconnected using a plurality of adaptors to configure a plurality of interconnected pathways. The maze modules and the adaptors are removably engaged to each other using hook and loop fastening arrangements. The maze device is capable of being removably installed on a supporting surface (for example, floor), either outdoor or indoor.	11-20-2008
20120042578	Inflatable Enclosure and Inflatable Enclosure System - An inflatable enclosure comprises a plurality of modular inflatable wall structures connected to one other, the inflatable wall structures comprising inflatable walls and supporting structures. An inflatable enclosure system comprises a plurality of modular inflatable wall structures, at least one entrance module, and fans connected to the inflatable wall structure of the inflatable enclosure.	02-23-2012

Yan-Hua Chen, Greenville, NC US

Patent application number	Description	Published
20090136943	METHOD OF DETECTING CANCER USING DELTA-CATENIN - The present invention provides a method for detecting or screening for the presence of cancer in a subject. The method comprises obtaining, providing or collecting a tissue or fluid sample (such as a urine sample) from said subject, and then determining the presence or absence of delta-catenin in said sample, or increased levels of delta-catenin in said sample as compared to a normal or control subject. The presence of delta-catenin in said sample, or increased levels of delta-catenin in said sample, indicating said subject is afflicted with or at least at risk of developing cancer.	05-28-2009
20110236890	METHOD OF SCREENING FOR CANCER BY DETECTING MUTATIONS IN THE DELTA-CATENIN GENE PROMOTER AND 5'-UNTRANSLATED REGION - A method for screening for risk of cancer in a subject is carried out by detecting the presence or absence of at least one mutation in the delta-catenin gene promoter or 5′ untranslated region in a biological sample from said subject, the presence of such mutation or an increased frequency of mutation indicating said subject is afflicted with or at least at risk of developing cancer.	09-29-2011

Y. T. Chen, Chapel Hill, NC US

Patent application number	Description	Published
20090053713	Isolated nucleic acids and polypeptides associated with glucose homeostasis disorders and method of detecting the same - An isolated and substantially pure nucleic acid sequence located between D20S119 and D20S178 on human chromosome 20q13, the nucleic acid sequence including: a nucleic acid sequence coding for a glucose transporting protein and having the sequence shown in SEQ ID NO: 1; or a nucleic acid sequence having at least 70% sequence identity with the nucleic acid sequence shown in SEQ ID NO: 1. The disclosed nucleic acid sequences map to a locus associated with human Type II diabetes mellitus and, therefore, therapeutic and diagnostic screening methods, which accommodate naturally and artificially occurring polymorphisms, are also disclosed.	02-26-2009

Yuan-Tsong Chen, Chapel Hill, NC US

Patent application number	Description	Published
20100254966	TREATMENT OF GLYCOGEN STORAGE DISEASE TYPE II - Methods of treating glycogen storage disease type II, by administering acid α-glucosidase, are described, as are compositions for use in treatment of glycogen storage disease type II.	10-07-2010
20120058132	Treatment of glycogen storage disease type II - Methods of treating glycogen storage disease type II, by administering acid α-glucosidase, are described, as are compositions for use in treatment of glycogen storage disease type II.	03-08-2012

Yuan-Tsong Chen, Durham, NC US

Patent application number	Description	Published
20110104187	METHOD OF TREATING GLYGOGEN STORAGE DISEASE - The present invention relates, in general, to Glycogen Storage Disease and, in particular, to a method of treating Glycogen Storage Disease-type-III and to compounds and compositions suitable for use in such a method.	05-05-2011

Yuchen Chen, Chapel Hill, NC US

Patent application number	Description	Published
20090098175	METHODS AND COMPOSITIONS FOR DELIVERY OF GROWTH FACTOR TO FIBROUS CONNECTIVE TISSUE - The presently disclosed subject matter relates to a peptide composition for non-covalently localizing fibrous connective tissue-inducing growth factor to a surface of an implant, the composition comprising a peptide having binding affinity for a surface material of an implant coupled to a peptide having binding affinity for a fibrous connective tissue-inducing growth factor. Methods are provided for delivering fibrous connective tissue-inducing growth factor GDF-7 in an amount effective to promote fibrous connective tissue repair and fibrous connective tissue formation. Also provided are methods of applying the peptide composition to an implant by contacting the composition with a surface of the implant; and kits comprising the compositions.	04-16-2009
20110117165	IMPLANTABLE BONE GRAFT MATERIALS - Compositions and methods are provided for promoting bone growth. An implantable bone graft material is provided comprising a resorbable ceramic and a resorbable polymer, wherein the polymer comprises a covalently attached BMP binding peptide. In addition, an implantable bone graft material is provided consisting essentially of a resorbable β-TCP and a resorbable polymer, wherein the β-TCP has a total porosity of about 50% or greater and wherein the β-TCP has a particle size ranging from about 100 micron to about 300 micron. The implantable bone graft materials are useful for promoting bone growth in a subject.	05-19-2011
20110117167	METHODS AND COMPOSITIONS FOR SOFT TISSUE REPAIR - Compositions and methods for tissue repair are provided including cell binding peptides and growth factor binding peptides. The cell binding peptides bind to one or more of stem cells, fibroblasts, or endothelial cells. The growth factor binding peptides include platelet derived growth factor (PDGF) binding peptides and growth differentiation factor (GDF) binding peptides. The tissue for repair includes tendon, muscle, connective tissue, ligament, cardiac tissue, vascular tissue, or dermis. Implantable devices for tissue repair are provided to which the cell and growth factor binding peptides are attached, such as acellular extracellular matrix having attached binding peptide.	05-19-2011
20110223142	METHODS AND COMPOSITIONS FOR SOFT TISSUE REPAIR - Compositions and methods for tissue repair are provided including cell binding peptides and growth factor binding peptides. The cell binding peptides bind to one or more of stem cells, fibroblasts, or endothelial cells. The growth factor binding peptides include platelet derived growth factor (PDGF) binding peptides and growth differentiation factor (GDF) binding peptides. The tissue for repair includes tendon, muscle, connective tissue, ligament, cardiac tissue, vascular tissue, or dermis. Implantable devices for tissue repair are provided to which the cell and growth factor binding peptides are attached, such as acellular extracellular matrix having attached binding peptide.	09-15-2011

Yuming Chen, Cary, NC US

Patent application number	Description	Published
20080231201	LED LIGHTING FIXTURE - A light-emitting diode (LED) lighting fixture is provided as a potential solid state lighting (SSL) replacement fixture for a conventional HID lamp fixture. The LED lighting fixture includes a main housing having a bottom surface supporting an array of LEDs, a top surface and sides, and at least one driver provided in a side housing attached to a side of the main housing to drive the LED array. The thickness of the side housing is equal to or greater than the thickness of the main housing. A plurality of heat spreading fins is arranged on the top surface of the main housing.	09-25-2008
20100296289	LED LIGHTING FIXTURE - A light emitting diode (LED) lighting fixture for achieving a desired illumination pattern includes a panel and one or more LEDs attached to a surface of the panel. One or more of the LEDs may be mounted at an angle to the surface.	11-25-2010
20110069488	LED LIGHTING FIXTURE - A light-emitting diode (LED) lighting fixture is provided as a potential solid state lighting (SSL) replacement fixture for a conventional HID lamp fixture. The LED lighting fixture includes a main housing having a bottom surface supporting an array of LEDs, a top surface and sides, and at least one driver provided in a side housing attached to a side of the main housing to drive the LED array. The thickness of the side housing is equal to or greater than the thickness of the main housing. A plurality of heat spreading fins is arranged on the top surface of the main housing.	03-24-2011

Yunching Chen, Chapel Hill, NC US

Patent application number	Description	Published
20110117141	METHODS AND COMPOSITIONS COMPRISING NOVEL CATIONIC LIPIDS - Provided herein are novel cationic lipids, compositions comprising the cationic lipids, and methods of using the cationic lipids. In some claims, the cationic lipids have cytotoxic activity and can be used alone or in combination with a cytotoxic bioactive compound to kill a cell. In some of these claims, the cationic lipid enhances the cytotoxic activity of the cytotoxic bioactive compound. Methods for treating a subject afflicted with a disease or unwanted condition are provided, wherein the method comprises administering a delivery system comprising a novel cationic lipid to the subject. The invention further provides methods for making delivery systems comprising the novel cationic lipids of the invention.	05-19-2011

Zibin Chen, Durham, NC US

Patent application number	Description	Published
20090069302	CHEMICAL COMPOUNDS - The present invention relates generally to novel therapeutic compounds and AXOR 109 agonists, and processes for the manufacture and use of the same.	03-12-2009

Zuofeng Chen, Chapel Hill, NC US

Patent application number	Description	Published
20110042227	Ruthenium or Osmium Complexes and Their Uses as Catalysts for Water Oxidation - The present invention provides ruthenium or osmium complexes and their uses as a catalyst for catalytic water oxidation. Another aspect of the invention provides an electrode and photo-electrochemical cells for electrolysis of water molecules.	02-24-2011