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Chen, Foster City

Chen-Hsieh Chen, Foster City, CA US

Patent application numberDescriptionPublished
20100224454Stepless pressure-varying shock absorber - A shock absorber includes a partitioning board fixed in a chamber of a cylinder to separate the chamber into first and second compartments receiving a damping fluid. The partitioning board includes a first through-hole in communication with the first and second compartments. A buffering disc is mounted in the chamber and forms a bottom end of the second compartment. A rod is slidably received in the chamber and slideably extends through the first through-hole. A damping valve is securely mounted around the rod and is slideably received in the first compartment. The rod has downwardly decreasing cross sections. A gap is formed between an inner periphery of the first through-hole and an outer periphery of the rod. When the rod moves downward, an area of the gap decreases gradually to gradually increase resistance to the damping fluid flowing from the first compartment into the second compartment via the first through-hole.09-09-2010

Jin-Long Chen, Foster City, CA US

Ke (kelly) Chen, Foster City, CA US

Patent application numberDescriptionPublished
20120123955CALCULATION ENGINE FOR COMPENSATION PLANNING - A method for managing compensation of users. The method includes identifying a first formula that is associated with a first compensation metric, where the first formula includes reference to a second compensation metric; computing a value for the second compensation metric based on evaluating a second formula associated with the second compensation metric; and computing a value for the first compensation metric for one or more users of the computer system based on the first formula and the value of the second compensation metric.05-17-2012

Ruihan Chen, Foster City, CA US

Patent application numberDescriptionPublished
20090324592Compositions and methods for the diagnosis and treatment of tumor - The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.12-31-2009

Ruihong Chen, Foster City, CA US

Patent application numberDescriptionPublished
20090118240LOCAL TREATMENT OF NEUROFIBROMAS - A method for treating a neurofibroma, e.g. dermal neurofibroma, a subdermal neurofibroma, or a superficial plexiform neurofibroma, in a subject in need of such treatment is disclosed. The method comprises locally applying a composition to a neurofibroma either topically or intralesionally. This method does not encompass systemic administration of the composition to the subject to have an effect on the neurofibromas. Compositions useful for such treatments and methods of preparing the compositions are disclosed.05-07-2009
20100292218Treatment Of Neurofibromatosis With Radicicol And Its Derivatives - The present invention provides compounds of formulae Ia, Ia′, IIa, IIa′, IIIa, IIIa′, IVa, or Va and the therapeutic use thereof. The present invention also includes methods of treating NF2-deficient or NF1-deficient cells or neurodegenerative diseases with radicicol or its derivatives, such as one or more compounds of formula I, II, III, IV, V, Ia, Ia′, IIa, IIa′, IIIa, IIIa′, IVa, or Va. Furthermore, the present invention is directed to methods of inhibiting the growth of NF2-deficient or NF1-deficient tumors. The methods comprise contacting NF2-deficient or NF1-deficient tumor cells with radicicol or its derivatives, such as one or more compounds of formula I, II, III, IV, V, Ia, Ia′, IIa, IIa′, IIIa, IIIa′, IVa, or Va. The present invention is also directed to the combinational use of radicicol or its derivatives, such as one or more compounds of formula I, II, III, IV, V, Ia, Ia′, IIa, IIa′, IIIa, IIIa′, IVa, or Va with at least one additional active agent, such as one or more HSP90 inhibitors.11-18-2010
20110190237Macrocyclic Prodrug Compounds Useful as Therapeutics - The present invention includes macrocyclic prodrug compounds, pharmaceutical compositions containing them. The present invention also includes use of these compounds in the treatment of various diseases including an autoimmune disease, an inflammatory disease, a neurological or neurodegenerative disease, cancer, a cardiovascular disease, allergy, asthma, a hormone-related disease, and tumors or symptoms resulting from neurofibromatosis.08-04-2011

Patent applications by Ruihong Chen, Foster City, CA US

Ruxin Chen, Foster City, CA US

Patent application numberDescriptionPublished
20110191107Structure for Grammar and Dictionary Representation in Voice Recognition and Method for Simplifying Link and Node-Generated Grammars - A speech recognition engine is provided with an acoustic model and a layered grammar and dictionary library. The layered grammar and dictionary library includes a language and non-grammar layer that supplies types of rules a grammar definition layer can use and defines non-grammar the speech recognition engine should ignore. The layered grammar and dictionary library also includes a dictionary layer that defines phonetic transcriptions for word groups the speech recognition engine is meant to recognize when voice input is received. The layered grammar and dictionary library further includes a grammar definition layer that applies rules from the language and non-grammar layer to define combinations of word groups the speech recognition system is meant to recognize. Voice input is received at a speech recognition engine and is processed using the acoustic model and the layered grammar and dictionary library.08-04-2011

Sei-Yu Chen, Foster City, CA US

Patent application numberDescriptionPublished
20080267863Method of Diagnosing, Monitoring, Staging, Imaging and Treating Colon Cancer - The present invention provides new methods for detecting, diagnosing, monitoring, staging, prognosticating, imaging and treating colon cancer.10-30-2008

Xiaocheng Chen, Foster City, CA US

Patent application numberDescriptionPublished
20120082666ANTIBODY COMPOSITIONS AND METHODS OF USE - The invention provides compositions comprising anti-gH antibodies and anti-Complex I antibodies as well as methods of using the same.04-05-2012

Xiaowu Chen, Foster City, CA US

Patent application numberDescriptionPublished
20110288053ANTIVIRAL PHOSPHONATE ANALOGS - The invention is related to phosphorus substituted compounds with antiviral activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.11-24-2011

Xiaoyi Chen, Foster City, CA US

Patent application numberDescriptionPublished
20090325387METHODS AND APPARATUS FOR IN-SITU CHAMBER DRY CLEAN DURING PHOTOMASK PLASMA ETCHING - Embodiments of the invention include method for in-situ chamber dry clean after photomask plasma etching. In one embodiment, the method includes placing a photomask upon a support pedestal, introducing a process gas into a process chamber, forming a plasma from the process gas, etching a chromium containing layer disposed on the photomask in the presence of the plasma, removing the photomask from the support pedestal, placing a dummy substrate on the pedestal and performing an in-situ dry cleaning process by flowing a cleaning gas containing O12-31-2009

Patent applications by Xiaoyi Chen, Foster City, CA US

Zhi-Ying Chen, Foster City, CA US

Patent application numberDescriptionPublished
20100075401MINICIRCLE DNA VECTOR PREPARATIONS AND METHODS OF MAKING AND USING THE SAME - The present invention provides minicircle nucleic acid vector formulations for use in administering to a subject, wherein the minicircle nucleic acid vectors include a polynucleotide of interest, a product hybrid sequence of a unidirectional site-specific recombinase, and are devoid of plasmid backbone bacterial DNA sequences. Also provided are methods of producing the subject formulations as well as methods for administering the minicircle nucleic acid vector formulations to a subject. The subject methods and compositions find use in a variety of different applications, including both research and therapeutic applications.03-25-2010
20110118333Use on Minicircle vectors for cardiac gene therapy - Compositions and methods are provided for the treatment of an ischemic cardiovascular condition by providing a patient with a novel non-viral minicircle DNA vector comprising polynucleotide sequences that potentiate HIF-1 activity, including RNAi or antisense agents selective for proteins involved in HIF1 inactivation.05-19-2011
20110126306Circular Nucleic Acid Vectors, and Methods for Making and Using the Same - Circular nucleic acid vectors that provide for persistently high levels of protein expression are provided. The circular vectors of the subject invention are to characterized by being devoid of expression-silencing bacterial sequences, where in many embodiments the subject vectors include a unidirectional site-specific recombination product hybrid sequence in addition to an expression cassette. Also provided are methods of using the subject vectors for introduction of a nucleic acid, e.g., an expression cassette, into a target cell, as well as preparations for use in practicing such methods. The subject methods and compositions find use in a variety of different applications, including both research and therapeutic applications. Also provided is a highly efficient and readily scalable method for producing the vectors employed in the subject methods, as well as reagents and kits/systems for practicing the same.05-26-2011

Patent applications by Zhi-Ying Chen, Foster City, CA US