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Chen, Edison

Alex M. Chen, Edison, NJ US

Patent application numberDescriptionPublished
20090131465Synthesis and crystalline forms of melanocortin-4 receptor agonist - The present invention relates to a process for producing crystalline N-[1-((3R)-1′-{[(3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-yl]carbonyl}-6-chloro-5-methyl-2,3-dihydrospiro[indene-1,4′-piperidine]-3-yl)-1-methylethyl]acetamide, and novel salts, solvates, hydrates and polymorphs thereof.05-21-2009
20090270477POLYMORPHS OF A HYDROISOINDOLINE TACHYKININ RECEPTOR ANTAGONIST - This application is directed to a novel polymorph of a hydroisoindoline tachykinin receptor antagonist having the following structural formula A.10-29-2009

Chao C. Chen, Edison, NJ US

Patent application numberDescriptionPublished
20110046740SPINAL IMPLANTS, SURGICAL INSTRUMENT SETS AND METHODS OF USING THE SAME - The present invention provides a spinal implant for stabilizing adjacent vertebrae of a patient, comprising (i) two or more cages; and (ii) a support which is returnable from a constrained linear shape to an expanded shape and affixed to each of the two or more cages, said implant having a first configuration to arrange the cages in order when the support is in the constrained linear shape, and a second configuration that gives a transformed arrangement of the cages to define a plane by the cages and the support when the support is in the expanded shape. Also provided are a surgical instrument set and a method for implanting a spinal implant to a disc space of a patient.02-24-2011

Chao-Chin Chen, Edison, NJ US

Patent application numberDescriptionPublished
20080215086SINGLE DISC INTRALUMINAL FIXATION PATENT FORAMEN OVALE CLOSURE DEVICE - A device and method for deploying a mechanical closure device for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart. The single disc mechanical closure device is comprise of a distal and proximal anchor constrained by a closure line to facilitate mechanical closure by bringing the distal and proximal anchors into close proximity along the closure line.09-04-2008
20090171388VASCULAR CLOSURE DEVICE - A biocompatible material may be configured into any number of implantable medical devices including a vascular closure device. The vascular closure device includes a fibrous structure formed from at least one randomly oriented fiber, the randomly oriented fiber comprising at least one polymer, and at least one agent, in therapeutic dosage, incorporated into at least one of the fibrous structure and the at least one randomly oriented fiber.07-02-2009
20090318955VASCULAR CLOSURE DEVICE - The present invention provides a porous structure that works very effectively to seal a puncture site with optimum porosity, absorbent capacity and perfect anatomical fit. The plug density and other fiber properties/geometry (total denier; number of filaments; etc) have provided an efficient structure that allows instantaneous absorption of blood during deployment. The final size of the plug with absorbed fluids provides an anatomical fit and seals the puncture site within few minutes after deployment.12-24-2009
20110022080SINGLE DISC INTRALUMINAL FIXATION PATENT FORAMEN OVALE CLOSURE DEVICE - A device and method for deploying a mechanical closure device for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart. The single disc mechanical closure device is comprise of a distal and proximal anchor constrained by a closure line to facilitate mechanical closure by bringing the distal and proximal anchors into close proximity along the closure line.01-27-2011

Patent applications by Chao-Chin Chen, Edison, NJ US

Cheo-Chin Chen, Edison, NJ US

Dandan Chen, Edison, NJ US

Patent application numberDescriptionPublished
20110065144METHOD OF MEASURING EFFECTS OF COMPONENTS ON CELL REACTIVE OXYGEN SPECIES PRODUCTION - A method of determining the effects of a test component on intracellular ROS levels. The method can be used in marketing or in screening for useful components in reducing ROS levels in cells adversely affected by increased ROS generation.03-17-2011

Kevin X. Chen, Edison, NJ US

Patent application numberDescriptionPublished
201000986614,5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS - The present invention relates to 4,5-ring annulated indole derivatives, compositions comprising at least one 4,5-ring annulated indole derivatives, and methods of using the 4,5-ring annulated indole derivatives for treating or preventing a viral infection or a virus-related disorder in a patient. Wherein ring Z, of formula (I), is a cyclopentyl, cyclopentenyl, 5-membered heterocycloalkyl, 5-membered heterocycloalkenyl or 5-membered heteroaryl ring.04-22-2010
201002607113-AMINOSULFONYL SUBSTITUTED INDOLE DERIVATIVES AND METHODS OF USE THEREOF - The present invention relates to 3-Aminosulfonyl Substituted Indole Derivatives, compositions comprising at least one 3-Aminosulfonyl Substituted Indole Derivative, and methods of using the 3-Aminosulfonyl Substituted Indole Derivatives for treating or preventing a viral infection or a virus-related disorder in a patient.10-14-2010
201003229015, 6-RING ANNULATED INDOLE DERIVATIVES AND USE THEREOF - The present invention relates to 5,6-ring annulated indole derivatives of the formula (I), compositions comprising at least one 5,6-ring annulated indole derivatives, and methods of using the 5,6-ring annulated indole derivatives for treating or preventing a viral infection or a virus-related disorder in a patient.12-23-2010
201100334172,3-SUBSTITUTED INDOLE DERIVATIVES FOR TREATING VIRAL INFECTIONS - The present invention relates to 2,3-Substituted Indole Derivatives, compositions comprising at least one 2,3-Substituted Indole Derivative, and methods of using the 2,3-Substituted Indole Derivatives for treating or preventing a viral infection or a virus-related disorder in a patient.02-10-2011
20110104109TETRACYCLIC INDOLE DERIVATIVES AND THEIR USE FOR TREATING OR PREVENTING VIRAL INFECTIONS - The present invention relates to Tetracyclic Indole Derivatives, compositions comprising at least one Tetracyclic Indole Derivative, and methods of using the Tetracyclic Indole Derivatives for treating or preventing a viral infection or a virus-related disorder in a patient.05-05-2011
20110104110SUBSTITUTED INDOLE DERIVATIVES AND METHODS OF USE THEREOF - The present invention relates to Substituted Indole Derivatives, compositions comprising at least one Substituted Indole Derivative, and methods of using these Substituted Indole Derivatives for treating or preventing a viral infection or a virus-related disorder in a patient.05-05-2011

Patent applications by Kevin X. Chen, Edison, NJ US

Michell Chen, Edison, NJ US

Patent application numberDescriptionPublished
20090092567OIL-CONTAINING COMPOSITIONS EXHIBITING REDUCED FEATHERING - The invention relates to compositions containing at least one oil, at least one silicone elastomer, at least one wax, at least one filler, and at least one coloring agent as well as to methods of making and using such compositions.04-09-2009
20090246159Composition and Process for Treating Keratinous Substrates With At Least Two Immiscible Cosmetic Compositions - A process for treating a keratinous substrate involving: (a) providing at least a first composition having a continuous phase whose major ingredient has a solubility parameter corresponding to δ; (b) providing at least a second composition having a continuous phase whose major ingredient has a solubility parameter corresponding to δ′; and (c) combining (a) and (b) prior to, or during, their application onto the keratinous substrate, and wherein the difference between δ and δ′ is greater than 12, and wherein the major ingredient is chosen from a hydrophilic polar material, an organic non-polar material and an inorganic non-polar material.10-01-2009
20110020255COMPOSITION CONTAINING A POLAR MODIFIED POLYMER - The invention relates to a physiologically acceptable composition, especially a cosmetic composition, comprising at least one polar modified polymer, as well as to methods of using such compositions.01-27-2011
20110129431COMPOSITION CONTAINING A POLYORGANOSILOXANE POLYMER, A THICKENING AGENT AND AT LEAST ONE VOLATILE ALCOHOL - The invention relates to a physiologically acceptable composition, especially a cosmetic composition, comprising (a) at least one polyorganosiloxane containing polymer comprising at least one moiety which comprises at least one polyorganosiloxane group consisting of 1 to about 1000 organosiloxane units in the chain of the moiety or in the form of graft, and at least two groups capable of establishing hydrogen interactions; (b) at least one volatile alcohol; and (c) at least one thickening agent, as well as to methods of using such compositions and kits containing such compositions.06-02-2011

Patent applications by Michell Chen, Edison, NJ US

Qinghao Chen, Edison, NJ US

Patent application numberDescriptionPublished
20100228036PROCESS FOR MAKING GLUCOCORTICOID RECEPTOR LIGANDS - The invention encompasses a process for making 2-[1-phenyl-5-hydroxy-4alpha-methyl-hexahydrocyclopenta[f]indazol-5-yl]ethyl phenyl derivatives, which are glucocorticoid receptor ligands, useful for the treatment of inflammatory and immunological diseases.09-09-2010

Roger S.c. Chen, Edison, NJ US

Patent application numberDescriptionPublished
20090298882THIOXOISOINDOLINE COMPOUNDS AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME - Provided are thioxo isoindoline compounds, and pharmaceutically acceptable salts, solvates, and stereoisomers, thereof. Methods of use, and pharmaceutical compositions of these compounds are disclosed.12-03-2009

Xiao Chen, Edison, NJ US

Patent application numberDescriptionPublished
20100227873NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF - The present invention provides compounds of Formula (I):09-09-2010

Patent applications by Xiao Chen, Edison, NJ US