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Chen, Brookline
David M. Chen, Brookline, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090267699 | TIMING OSCILLATORS AND RELATED METHODS - Timing oscillators as well as related methods and devices are described. A timing oscillator may include a mechanical resonating structure with major elements and minor elements coupled to the major element. The timing oscillator can generate stable signals with low phase noise at very high frequencies which allows a timing oscillator to be used effectively in a number of devices including computers and mobile phones for time and data synchronization purposes. The signal generated by the timing oscillator can be tuned using a driver circuit and a compensation circuit. | 10-29-2009 |
| 20090267700 | TIMING OSCILLATORS AND RELATED METHODS - Timing oscillators as well as related methods and devices are described. A timing oscillator may include a mechanical resonating structure with major elements and minor elements coupled to the major element. The timing oscillator can generate stable signals with low phase noise at very high frequencies which allows a timing oscillator to be used effectively in a number of devices including computers and mobile phones for time and data synchronization purposes. The signal generated by the timing oscillator can be tuned using a driver circuit and a compensation circuit. | 10-29-2009 |
| 20100181868 | MULTI-PORT MECHANICAL RESONATING DEVICES AND RELATED METHODS - Multi-port devices having multiple electrical ports are described, as are related methods. Some of the multi-port devices may have two input ports and two output ports, and may be driven differentially, in a single-ended mode, in a single-ended to differential mode, or in a differential to single-ended mode. The multi-port devices may include one or more transducers coupled to the electrical ports. | 07-22-2010 |
| 20100182102 | MECHANICAL RESONATING STRUCTURES INCLUDING A TEMPERATURE COMPENSATION STRUCTURE - Mechanical resonating structures are described, as well as related devices and methods. The mechanical resonating structures may have a compensating structure for compensating temperature variations. | 07-22-2010 |
| 20100301703 | INTEGRATION OF PIEZOELECTRIC MATERIALS WITH SUBSTRATES - Devices having piezoelectric material structures integrated with substrates are described. Fabrication techniques for forming such devices are also described. The fabrication may include bonding a piezoelectric material wafer to a substrate of a differing material. A structure, such as a resonator, may then be formed from the piezoelectric material wafer. | 12-02-2010 |
| 20100314969 | MECHANICAL RESONATING STRUCTURES AND METHODS - Apparatus and methods of connecting mechanical resonating structures to a body are described. Multi-element anchors may include a flexible portion that flexes when the mechanical resonating structure vibrates. The flexible portion may have a length related to the resonance frequency of the mechanical resonating structures. Some of the multi-element anchors include elements that are oriented perpendicularly to each other. MEMS incorporating such structures are also described. | 12-16-2010 |
Jianzhu Chen, Brookline, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100040645 | IN VIVO CTL ELICITATION BY HEAT SHOCK PROTEIN FUSION PROTEINS MAPS TO A DISCRETE DOMAIN AND IS CD4+ T CELL-INDEPENDENT - The present invention relates to a method of inducing a CD8 | 02-18-2010 |
| 20100136072 | Polymeric Coatings that Inactivate Viruses and Bacteria - Hydrophobic polymeric coatings which can be non-covalently applied to solid surfaces such as metals, plastics, glass, polymers, textiles, and other substrates such as fabrics, gauze, bandages, tissues, and other fibers, in the same manner as paint, for example, by brushing, spraying, or dipping, to make the surfaces virucidal and bactericidal, have been developed. | 06-03-2010 |
| 20100204297 | INFLUENZA THERAPEUTIC - The present invention provides compositions comprising an RNAi-inducing entity targeted to an influenza virus transcript and any of a variety of delivery agents. The invention further includes methods of use of the compositions for inhibiting a biological activity of an influenza virus and/or for treatment or prevention of influenza. The invention provides target portion sequences that are favorably conserved for RNAi across a plurality of influenza virus A strains isolated from human hosts and/or avian hosts and RNAi-inducing entities, e.g., siRNAs and shRNAs, targeted to such favorably conserved target portions. The invention provides a variety of nucleic acids comprising sequences identical or complementary to at least a portion of one or more of these favorably conserved target portion sequences. The invention further provides methods and compositions for delivering RNAi-inducing agents to an organ or tissue of a mammalian subject, e.g., to the lung. Methods of diagnosing influenza and determining the susceptibility of an influenza virus to inhibition by an RNAi-inducing agent are also provided. Transgenic animals that express an RNAi-inducing agent targeted to an influenza gene are another aspect of the invention. | 08-12-2010 |
Yajie Chen, Brookline, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100173101 | METHOD OF MANUFACTURING THICK-FILM, LOW MICROWAVE LOSS, SELF-BIASED BARIUM-HEXAFERRITE HAVING PERPENDICULAR MAGNETIC ANISOTROPY - A method of producing a relatively-thick film of a magnetic material on a substrate for use in microwave and millimeter wave devices is disclosed. The method includes preparing a wet paste comprising a binder material, glass frit, and a finely-grained magnetic material; applying the wet paste over a stencil, template or mask disposed on the substrate, to form a film on a surface of the substrate; drying the wet paste within an applied magnetic field, to vaporize fluid and organic compounds in the binder material and to produce a desired magnetic orientation in the magnetic film; and sintering the magnetic film. Hot pressing the magnetic film during sintering by adding weight on the film improves density. | 07-08-2010 |