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Che, US
Austin Che, Boston, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120040870 | Method For Assembly Of Polynucleic Acid Sequences - The present invention provides a method for the assembly of a polynucleic acid sequence from a plurality of nucleic acid sequences in which the polynucleic acid sequence is of a formula N | 02-16-2012 |
Austin J. Che, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100305197 | Conditionally Active Ribozymes And Uses Thereof - This invention relates, at least in part, to conditionally active ribozymes and uses of such ribozymes. Some aspects of this invention relate to the engineering of conditionally active ribozymes. In some embodiments, the splicing activity of such ribozymes is modulated by at least one regulatory element. Some aspects of this invention relate to uses of conditionally active ribozymes. RNA detection technology, conditional RNA expression technology, cell tagging technology, therapeutic approaches, and synthetic biology are examples of areas in which conditionally active ribozymes according to some aspects of the invention can be employed. RNA folding models useful in the design of conditionally active ribozymes with altered splicing efficiency and/or substrate specificity are provided. Compositions and methods to manufacture medicaments containing conditionally active ribozymes are also described. | 12-02-2010 |
Chih Chuan Che, Norwood, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090206887 | Differential current output driver with overvoltage protection - A differential current output driver and a method for overvoltage protection of a differential current output driver circuit are provided. The output driver includes a differential current output driver circuit operable by a power supply voltage and including first and second driver transistors in a differential current configuration and first and second output pads, and an overvoltage protection circuit configured to generate a protected voltage in response to a voltage on at least one of the first and second output pads and an absence of the power supply voltage, and to apply the protected voltage to at least one transistor of the differential current output driver circuit. | 08-20-2009 |
Li Che, Broadview Heights, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20110143452 | CRYOGENIC VIAL - Provided is a cryogenic vial for storing at least one sample, the vial including a pipette, a cap assembly, and a container having at least one opening in a body portion of the container to allow liquid and/or gas to enter and/or exit the vial to balance the pressure between the inside of vial and the outside environment. The cryogenic vial allows for reduced processing time and minimizes the chance a sample may be lost or damaged while being processed. | 06-16-2011 |
Michelle Y. Che, Richardson, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20100058039 | INSTRUCTION FETCH PIPELINE FOR SUPERSCALAR DIGITAL SIGNAL PROCESSORS AND METHOD OF OPERATION THEREOF - A next program counter (PC) value generator. The next PC value generator includes a discontinuity decoder that is provide to detect a discontinuity instruction among a plurality of instructions and a tight loop decoder that is provide to: a) detect a tight loop instruction, and b) provide a tight loop instruction target address. The next PC value generator further includes a next PC value logic having a plurality of inputs: a first input coupled to an output of the discontinuity decoder, and a second input coupled to an output of the tight loop decoder. The next PC value logic provides as an output, without a stall, a control signal that a next PC value is to be loaded with the tight loop instruction target address if: the discontinuity decoder detects a discontinuity instruction, and the tight loop decoder detects a tight loop instruction. | 03-04-2010 |
Pao-Lin Che, Baltimore, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20100331677 | MARKER DELIVERY SYSTEM - A marker delivery system including a surgical needle defining a lumen. The surgical needle is adapted to receive a marker. The surgical needle includes a side opening substantially adjacent to a first end of the surgical needle. The marker delivery system also includes a plunger insertable into the surgical needle at a second end of the surgical needle. Depression of the plunger inside the lumen of the surgical needle pushes the marker through the side opening of the surgical needle. | 12-30-2010 |
Qinglin Che, Foxboro, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100130510 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES - The invention relates to certain compounds, or pharmaceutically acceptable salts, solvates, clathrates, or prodrugs thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders. | 05-27-2010 |
| 20110052643 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES - The invention relates to certain fused ring compounds, or pharmaceutically acceptable salts thereof, that are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders. | 03-03-2011 |
Tan N. Che, Federal Way, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20110006918 | FILTERING AIRCRAFT TRAFFIC FOR DISPLAY TO A PILOT - A method for filtering and presenting relevant aircraft traffic to a pilot may include determining a location and altitude of aircraft within a predetermined airspace relative to the pilot's own aircraft. The method may also include presenting a representation of the pilot's own aircraft and a representation of the location of each of the aircraft within the predetermined airspace in relation to the pilot's own aircraft on a display to the pilot. The method may additionally include filtering relevant aircraft within a selected filtering airspace relative to the pilot's own aircraft. The method may further include presenting the representation of the relevant aircraft within the selected filtering airspace in a selected format to distinguish the relevant aircraft within the selected filtering airspace from any other aircraft that may be presented in the display. | 01-13-2011 |
Wenyi Che, Rochester, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090098057 | SILICA-CORED CARRIER PARTICLE - A nanoparticulate imaging probe with an oxide core, a biocompatible polymeric shell covalently attached to the oxide core, a dye, and a cleavable spacer that covalently binds the dye to the probe. When the spacer is cleaved, the dye is liberated from the probe. The emissions of the dye are quenched when the dye is bound to the probe and not quenched when the dye is liberated from the probe. The spacer can be, for example, a peptide. The oxide core can be, for example, a silicon oxide core. | 04-16-2009 |
| 20090169482 | SILICA-CORED CARRIER PARTICLE - A nanoparticulate imaging probe with an oxide core, a biocompatible polymeric shell covalently attached to the oxide core, a dye, and a cleavable spacer that covalently binds the dye to the probe. When the spacer is cleaved, the dye is liberated from the probe. The emissions of the dye are quenched when the dye is bound to the probe and not quenched when the dye is liberated from the probe. The spacer can be, for example, a peptide. The oxide core can be, for example, a silicon oxide core. | 07-02-2009 |
Yanke Che, Salt Lake City, UT US
| Patent application number | Description | Published |
|---|---|---|
| 20100144043 | MOLECULAR FLUORESCENCE SENSOR FOR HIGHLY SENSITIVE AND SELECTIVE DETECTION OF MERCURY - A fluorescent sensor compound based on a perylene core is described and disclosed. The fluorescent sensor compound for detecting mercury can have a structure I: | 06-10-2010 |
| 20100197039 | FLUORESCENT MATERIALS FOR HIGHLY SENSITIVE AND SELECTIVE SENSING OF AMINES AND NANOFIBRIL MATERIALS MADE THEREFROM - A fluorescence sensory material with high sensitivity, selectivity, and photostability has been developed for vapor probing of organic amines. The sensory material is a perylene-3,4,9,10-tetracarboxyl compound having amine binding groups and the following formula | 08-05-2010 |