Charles Steven
Charles Steven Defina, Oakland, CA US
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20120258953 | Benzoxazepines as Inhibitors of PI3K/mTOR and Methods of Their Use and Manufacture - The invention is directed to Compounds of Formula (I): the invention provides compounds that inhibit, regulate, and/or modulate P13K and/or mTOR that are useful in the treatment of hyperproliferative diseases, such as cancer, in mammals. This invention also provides methods of making the compound methods of using such compounds in the treatment of hyperproliferative diseases in mammals, especially humans, and to pharmaceutical compositions containing such compounds. For example, cancer in which activity against PI3fC-alph mTOR, or both contributes to its pathology and/or symptomatology include breast cancer mantle cell lymphoma, renal cell carcinoma, acute myelogenous leukemia, chronic myelogenous leukemia, NPM/ALK-transformed anaplastic large cell lymphoma, diffu large B cell lymphoma, rhabdomyosarcoma, ovarian cancer, endometrial cancer, cervic cancer, non small cell lung carcinoma, small cell lung carcinoma, adenocarcinoma, col cancer, rectal cancer, gastric carcinoma, hepatocellular carcinoma, melanoma, pancreat cancer, prostate carcinoma, thyroid carcinoma, anaplastic large cell lymphoma, hemangiom glioblastoma, or head and neck cancer. | 10-11-2012 |
Charles Steven Johnson, Snohomish, WA US
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20140315516 | SELECTION OF WIRELESS DEVICES AND SERVICE PLANS - Disclosed are various embodiments for selection of wireless devices and service plans. A geographic location and a plurality of wireless preferences are associated with a user. Wireless service plans, offered by at least one wireless carrier that services the geographic location, that meet the wireless preferences associated with the user are determined. A user interface is generated that presents the wireless service plans in a ranked order that is determined utilizing at least the wireless preferences. | 10-23-2014 |
Charles Steven Lignafelt, Research Triangle Park, NC US
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20150142444 | AUDIO RENDERING ORDER FOR TEXT SOURCES - A method includes loading text content into at least one user device; applying at least one reading order to at least one text section of the text content to change a presentation order; converting the at least one text section to an audio output based upon the presentation order; and playing the audio output using the presentation order on the at least one user device. | 05-21-2015 |
Charles Steven Palardis, Tampa, FL US
Patent application number | Description | Published |
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20140235373 | Batting Ball On A Cable Having A Low Friction Surface To Provide Proper Swing Technique and Muscle Memory - A batting ball is slidably mounted on a line having a low friction surface to provide proper swing technique and muscle memory. A hook and eye turnbuckle is connected to an end of the cable by a thimble and clamp set. A swivel snap hook is connected to an end of the cable by a thimble and clamp set located opposite the hook and eye turn buckle. A bushing with a central opening is inserted and affixed into the ball opening. The bushing has a threaded end connected to an outer wall of the bushing. The central opening of the bushing will receive the cable. The balls are mounted onto the cable with a washer located at each end between the attaching elements and the balls. The washers act as a barrier to prevent the balls from being penetrated by the thimble and clamp set upon impact. | 08-21-2014 |