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Charles L.
Charles L. Barkley, Jr., Fort Worth, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20100108822 | Method for Suppressing Vibration in a Tiltrotor Aircraft - A method is disclosed for suppressing vibration in an aircraft having at least one pair of multiple-blade rotors. The first step of the method is to install in the aircraft at least one pair of vibration suppression devices to form a system, the devices of each system being mounted on opposing sides of the aircraft. Then, during operation of the aircraft, the next step is to rotate the at least one pair of rotors in a manner that causes the blades one of each pair of rotors to be out of phase from the other of each pair of rotors. The final step is to use the system to suppress vibrations caused by the out-of-phase rotation of the rotors. | 05-06-2010 |
Charles L. Biltz, Jr., San Antonio, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20090240216 | NEGATIVE PRESSURE TREATMENT SYSTEM WITH HEATING AND COOLING PROVISION - A method, and apparatus for the controlled acceleration, and/or retardation of the body's inflammatory response generally comprises a foam pad for insertion substantially into a wound site, a heating, a cooling pad for application over the wound site, a wound drape or sealing enclosure of the foam pad, the heating, and cooling pad at wound site. The foam pad is placed in fluid communication with a vacuum source for promotion of the controlled acceleration or retardation of the body's inflammatory response. The heating, and cooling provision controls the local metabolic function as part of the inflammatory response. | 09-24-2009 |
Charles L. Bisgaier, Ann Arbor, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20080213351 | Compositions and methods for dosing liposomes of certain sizes to treat or prevent disease - The present invention relates to pharmaceutical compositions comprising liposomes and methods of using such liposomes to prevent, treat, or manage a variety of diseases and/or bodily conditions. The liposomes may comprise large unilamellar vesicles (LUVs) alone or in combination with multilamellar vesicles (MLVs), small unilamellar vesicles (SUVs), or other therapeutics. The invention relates to liposomes having certain diameters administered to patients using specific doses and/or dosing regimens. | 09-04-2008 |
| 20080293633 | Pharmaceutical Formulations, Methods, and Dosing Regimens for the Treatment and Prevention of Acute Coronary Syndromes - The invention provides methods and formulations for treating and preventing acute coronary syndromes. The methods of the instant invention provide safe and effective doses of an Apolipoprotein A-I Milano: phospholipid complex to reduce and stabilize atherosclerotic plaque. Pharmaceutical formulations of the Apo A-I Milano:phospholipid complexes are also provided. | 11-27-2008 |
Charles L. Boatner, Jr., Belden, MS US
| Patent application number | Description | Published |
|---|---|---|
| 20110087313 | Thermal Compression Shirt - A thermal garment is tight fitting, often known as a compression shirt, and has a raw or composition rubber sleeve portion, which can be applied to either or both shoulder parts of the garment and/or to either or both elbow parts of the garment, with said rubber portion being covered in fabric and being attached to the garment and replacing that original portion of said garment. The garment with a composition sleeve portion is designed to avoid injury due to extreme playing conditions or improper muscle tension incurred by athletes, by insuring heat and compression to the shoulder joint or to the elbows. The garment also uses heat from the thermal portion of the garment to help in healing the area covered by way of thermotherapy (the use of heat on muscles, joints, tendons, and ligaments which increases blood flow to expedite the healing process). | 04-14-2011 |
Charles L. Brabenac, Portland, OR US
| Patent application number | Description | Published |
|---|---|---|
| 20100203836 | Reducing Interference From Closely Proximate Wireless Units - A wireless device may include two or more wireless interfaces capable of transmitting and/or receiving signals over separate wireless networks. To reduce the likelihood of interference, a processing unit may determine whether to permit a transmission under one wireless network when a reception under another wireless network is already in progress. | 08-12-2010 |
| 20110162061 | PORT-BASED PACKET FILTER - A method, apparatus, and program product for reducing unwanted host wake-up messages. A host computer finds a port in use by a host application, selects program information based on the port in use by the application, and sends the program information to a port filter. The port filter receives a packet that contains a port identifier. The port-filter uses the program information to decide whether there is a host application associated with the port identifier and sends a wake-up message to the host computer only when there is an associated host application. | 06-30-2011 |
Charles L. Bradenbaugh, Iv, York, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20080308592 | Contact Trip Mechanism For Nailer - A contact trip assembly for a power nailer, wherein a contact member includes a curved portion that loops rearwardly towards a handle of the nailer. Also provided is an adjustment assembly including an adjustment plate and a pinion gear, a trigger that is slidably engageable within a housing of the tool, a trigger lock including a ring element, an anti-discharge mechanism including a stop member, and a contact trip lock. | 12-18-2008 |
Charles L. Branch, Jr., Advance, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20100318132 | Spinal Implants and Methods With Extended Multi-Axial Anchor Assemblies - Systems and methods are provided that include a plate member engageable to the spinal column with an anchor assembly. The anchor assembly includes a coupling member having a post extending through at least one opening of the plate member and an anchor member pivotally captured in a receiver member of the coupling member below a lower surface of the plate member. A locking member secures the plate member to the coupling member. The coupling member includes an extended post with a proximal removable portion. The extended post facilitates placement of the plate member in position relative to the anchor assembly when engaged to the patient and be employed to reduce the plate member toward the anchor assembly when engaged to a vertebra. | 12-16-2010 |
| 20100319706 | Surgical Head Support Adapter - A planar support assembly for use with a patient body support, an extension support assembly, and a plurality of interchangeable head supports is provided. The extension support assembly is releasably mounted on a portion of the patient body support such that the extension support assembly extends outwardly from the patient body support. The planar support assembly includes a generally planar support configured to releasably attach to an end of the extension support assembly opposite the patient body support. The planar support is configured to receive and support one of a plurality of interchangeable head supports, and the planar support is adjustable with respect to the patient body support in two or more dimensions. | 12-23-2010 |
| 20110282263 | Subdural Drainage Catheter with Flow Restoration Mechanism - A subdural drainage system includes (a) a subdural drainage device having an opening formed therethrough, said subdural drainage device having an upper portion, a body portion, and a lower portion; (b) a housing having an upper portion and lower portion, with said housing connected to said subdural drainage device; said housing movable between (i) a first configuration and (ii) a second configuration; and (c) a stylet positioned inside said housing, said stylet having an upper portion and a lower portion and configured such that said stylet is moved between (i) a withdrawn position with said stylet withdrawn from a portion of said subdural evacuation port device, and (ii) an extended position with said stylet extending through said subdural drainage device such that blockages are disrupted in the subdural drainage device when said housing is moved between said first and second housing configurations; and (e) an external drain opening formed on either said subdural drainage device or said housing. | 11-17-2011 |
Charles L. Britton, Jr., Alcoa, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20090212226 | SPACE CHARGE DOSIMETERS FOR EXTREMELY LOW POWER MEASUREMENTS OF RADIATION IN SHIPPING CONTAINERS - Methods and apparatus are described for space charge dosimeters for extremely low power measurements of radiation in shipping containers. A method includes insitu polling a suite of passive integrating ionizing radiation sensors including reading-out dosimetric data from a first passive integrating ionizing radiation sensor and a second passive integrating ionizing radiation sensor, where the first passive integrating ionizing radiation sensor and the second passive integrating ionizing radiation sensor remain situated where the dosimetric data was integrated while reading-out. Another method includes arranging a plurality of ionizing radiation sensors in a spatially dispersed array; determining a relative position of each of the plurality of ionizing radiation sensors to define a volume of interest; collecting ionizing radiation data from at least a subset of the plurality of ionizing radiation sensors; and triggering an alarm condition when a dose level of an ionizing radiation source is calculated to exceed a threshold. | 08-27-2009 |
| 20100072380 | SPACE CHARGE DOSIMETERS FOR EXTREMELY LOW POWER MEASUREMENTS OF RADIATION IN SHIPPING CONTAINERS - Methods and apparatus are described for space charge dosimeters for extremely low power measurements of radiation in shipping containers. A method includes insitu polling a suite of passive integrating ionizing radiation sensors including reading-out dosimetric data from a first passive integrating ionizing radiation sensor and a second passive integrating ionizing radiation sensor, where the first passive integrating ionizing radiation sensor and the second passive integrating ionizing radiation sensor remain situated where the dosimetric data was integrated while reading-out. Another method includes arranging a plurality of ionizing radiation sensors in a spatially dispersed array; determining a relative position of each of the plurality of ionizing radiation sensors to define a volume of interest; collecting ionizing radiation data from at least a subset of the plurality of ionizing radiation sensors; and triggering an alarm condition when a dose level of an ionizing radiation source is calculated to exceed a threshold. | 03-25-2010 |
Charles L. Bush, Jr., Fairfield, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20090076509 | Dynamic cervical plate - A dynamic subsidence plate is described having a first plate member and a second plate member in sliding engagement that may infinitely subside between a first and second assembled position. The plate includes a lock assembly associated with the first and second plate members. The lock assembly includes a ramp portion, an interference portion, and a bearing member situated between the ramp portion and the interference portion. The lock assembly of the plate is configured to allow movement of the first member with respect to the second member in a first direction in an infinite number of positions between a first assembled position and a second assembled position. Further, the lock assembly alternatively prevents movement of the first member with respect to the second member in an opposite second direction between the first and second assembled positions. | 03-19-2009 |
| 20090131988 | Cervical plate with a feedback device for selective association with bone screw blocking mechanism - A bone plate having at least one screw hole adapted to receive a bone screw, a blocker having a blocking end for blocking a bone screw from further backout of bone the blocker being predisposed in a blocking position wherein the blocking end at least partially overlaps a portion of the screw hole, the blocker being moveable from the blocking position by contact with the bone screw during insertion of the bone screw into the screw hole, and a blocker fixation element having an open orientation at which the blocker can move from the blocking position and a closed orientation preventing substantial movement of the blocker from the blocking position. The blocker fixation element cannot be moved to the closed orientation unless the screw head passes the blocker, thereby revealing that the blocker fixation element is in position to prevent substantial movement of the blocker. | 05-21-2009 |
Charles L. Caristan, Houston, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20100072182 | Fiber Laser Cutting Process with Multiple Foci - A process for laser cutting a workpiece comprising the steps of providing a fiber-type laser resonator; providing a workpiece to be cut having a thickness of at least 1 mm; generating a laser beam using the laser resonator; focusing the laser beam in several distinct focus points, at least one of said focus points being focused in the thickness of the workpiece to be cut; and cutting said workpiece at a speed of at least 20 m/min. | 03-25-2010 |
| 20100122970 | Support Table Frame For High Speed Laser Blanking - The present invention provides an apparatus for laser cutting that comprises a rigid support table frame having a X-axis and a Y-axis, and one or more bridge rail modules running across the Y-axis of the table frame, each bridge rail module comprising at least one hold-down device module. The present invention further provides a process for laser cutting a metal plate using this apparatus. | 05-20-2010 |
| 20100122971 | Process For Laser Cutting A Metal Plate - The present invention provides a process for laser cutting a metal plate that comprises a) providing at least a laser cutting device, b) providing a metal plate to be cut from a metal coil, c) providing at least a holding apparatus holding and maintaining the metal plate, d) cutting said metal plate by means of at least a laser beam delivered by said at least one laser cutting device In this process, during step d), the metal plate is first cut by a first line comprising at least a first cutting machine, into at least one peripheral blank, and at least one peripheral blank is subsequently fed to at least a second line comprising at least a second cutting machine, to be cut into several smaller individual final blanks. With regard to this process, the first line produces peripheral blanks faster than at least one second cutting machine of the second line can cut them into several smaller individual final blanks. During laser cutting in the second line, said peripheral blank is held and maintained in position by said at least one holding apparatus. | 05-20-2010 |
Charles L. Carrico, Jr., Burlington, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20110104742 | INTEGRATED SEQUENTIAL SAMPLE PREPARATION SYSTEM - The invention provides an integrated sequential sample preparation system using a sequential centrifuge for preparing samples for analysis. Methods of more efficiently preparing discrete samples sequentially for subsequent analysis are also provided. The apparatus and methods for sequentially preparing discrete samples provide improved operating efficiencies over conventional preparation processes that use batch centrifugation systems. Such advantages include reducing dwell time, increasing system throughput, reducing sample preparation system footprint, and improving precision of the analytical process. The integrated sequential preparation system with the integrated sequential centrifuge further provides the capability of handling critical or STAT samples without compromising the operating efficiencies achieved by preparing discrete samples in a sequential manner. | 05-05-2011 |
Charles L. Cattell, Jr., Jefferson, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20120032084 | DRIVE WITH CURVED LINEAR INDUCTION MOTOR - A curved linear induction motor direct drive is provided. The rotor of the motor drive is mechanically attached to a rotating frame which in turn holds other components. The rotor may comprise two layers, an aluminum ring to provide the principal magnetic interaction with the stator, and a steel ring to provide mechanical strength. Such a rotor ring may be manufactured with a compression fit. | 02-09-2012 |
Charles L. Caverly, Red Wing, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20110078924 | SLIP-ON FOOTWEAR WITH FIT FEATURES - The present disclosure provides a slip-on boot with fit features that enable snug fit while still allowing for convenient foot entry and exit. Related methods of using and manufacturing a slip-on boot are also provided. | 04-07-2011 |
Charles L. Chen, San Jose, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110154212 | CLOUD-BASED USER INTERFACE AUGMENTATION - Method for providing augmented user interface (AUI). AUI is provided in response to a request. AUI configuration information is received, stored in preference file, and sent to remote server. Remote server receives request from computer to login user. Remote server authenticates user, retrieves and sends preference file to computer. Preference file contains information that allows computer to implement and configure AUI by directing output to AUI component. Remote server sends computer web-based API to enable browser to interface with an AUI application. API can include target callable by event handler to respond to HTML document browsing event by invoking AUI application. Remote server can send computer web-based, native, or browser plug-in AUI application. Computer can provide content rich navigation via API, AUI application and content navigation rules that define plural navigation paths through HTML document. Navigation paths providing AUI functionality to particular type of special needs user or user task. | 06-23-2011 |
| 20110273379 | DIRECTIONAL PAD ON TOUCHSCREEN - A computer-implemented user interface method for managing directional user inputs is disclosed. The method includes receiving sliding motion by a user on a touchscreen of a computing device, identifying a direction for the sliding motion; associating the direction for the sliding motion with one of a plurality of directions for a directional pad, and providing information about the associated one of the plurality of directions to an application that is executing on the computing device. | 11-10-2011 |
| 20120019465 | Directional Pad Touchscreen - A computer-implemented user interface method for managing directional user inputs is disclosed. The method includes receiving sliding motion by a user on a touchscreen of a computing device, identifying a direction for the sliding motion; associating the direction for the sliding motion with one of a plurality of directions for a directional pad, and providing information about the associated one of the plurality of directions to an application that is executing on the computing device. | 01-26-2012 |
Charles L. Combs, Jr., Holly, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20100158630 | CONVENIENCE NET HAVING SUBSTANTIALLY RIGID END RODS - A convenience net for use in a vehicle includes first and second rods, each having a first and a second end. The first and second rods are substantially rigid. A first cord extends between the first ends of the first and second rods, and a second cord extends between the second ends of the first and second rods. A mesh extends between the first and second rods and between the first and second cords. First and second attachment members are operatively connected to the first and second rods, respectively, and disposed between the first and second ends thereof. The first cord may be formed from an elastic material, and the second cord may be formed from a substantially inelastic material. A third cord may extend between the rods, and the mesh may extend between the rods and between the second and third cords, forming an envelope. | 06-24-2010 |
Charles L. Corley, Ii, Santa Rosa, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20120027063 | CALIBRATION SYSTEM AND METHOD - Receiving a modulated carrier signal that is modulated using a reference signal, wherein an acquisition by a digitizer is synced to the reference signal such that the modulated carrier signal has known timing with respect to a start of an acquisition within the digitizer. Further including routing the modulated carrier signal through a receiver system to generate a processed signal, receiving the processed signal at the digitizer, digitizing the processed signal at the digitizer, and determining a delay of the modulated carrier signal routed through the receiver system based on the timing of the processed signal. | 02-02-2012 |
Charles L. Cywin, Bethel, CT US
| Patent application number | Description | Published |
|---|---|---|
| 20090171089 | 1,6 NAPHTHRIDINES USEFUL AS INHIBITORS OF SYK KINASE - Disclosed are compounds of formula (I): | 07-02-2009 |
Charles L. Depenning, Marshalltown, IA US
| Patent application number | Description | Published |
|---|---|---|
| 20100059131 | Noise Level Reduction of Sparger Assemblies - A method results in a system configuration wherein positioning a plurality of spargers reduces noise levels caused by fluid passing through the plurality of spargers. The method includes providing the plurality of spargers, each sparger having a center line access and an outer diameter measurement. Each of the plurality of spargers is positioned in a manner such that a ratio of the distance between the center line access of each sparger to the outer diameter measurement of each sparger is greater than a pre-determined ratio value. A greater ratio results in a reduction of noise emitted. | 03-11-2010 |
Charles L. Flask, Warren, OH US
| Patent application number | Description | Published |
|---|---|---|
| 20100093204 | Electrical connector assembly - An electrical connector assembly includes a male connector, a female connector, and a sleeve. The male connector has a shoulder. The female connector is constructed to receive the male connector and has a flex arm with a nib. The sleeve is constructed to receive the female connector and has an inner surface. When the male connector, the female connector, and the sleeve are telescoped together, the inner surface of the sleeve overlaps the flex arm and forces engagement between the shoulder and the nib to eliminate relative movement between the male and female connectors. | 04-15-2010 |
Charles L. Gawaroski, Midlothian, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20080216850 | Restrictor attachment for unfiltered smoking article - A smoking article having an unfiltered tobacco rod, a connector attach to the tobacco rod and a mouthpiece. The connector includes a cavity, a transverse partition within the cavity, the transverse partition having at least one orifice, and a plurality of ventilation passages positioned around an outer periphery of the connector. Each of the plurality of ventilation passages includes an inlet and an outlet to provide ventilation to the cavity. The mouthpiece is adapted to attach to a downstream end of the connector. | 09-11-2008 |
Charles L. Griffith, Iii, The Woodlands, TX US
| Patent application number | Description | Published |
|---|---|---|
| 20100150809 | ENHANCEMENTS FOR A CHLOROSILANE REDISTRIBUTION REACTOR - The present invention includes a process and means for using two isolated by-products from the reaction of at least one of metallurgical silicon and silicon tetrachloride with at least one of anhydrous hydrogen chloride and hydrogen to produce trichlorosilane. The two isolated by-products are dichlorosilane and silicon tetrachloride. The present process reduces chlorosilane waste and improves efficiency of overall process for production of trichlorosilane for use in chemical vapor deposition of polysilicon for electronic and solar applications. The present invention further includes a chemical reactor for the reacting dichlorosilane with silicon tetrachloride to produce additional trichlorosilane. | 06-17-2010 |
Charles L. Guffey, Sweetwater, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20080211914 | APPARATUS AND METHOD FOR CAPTURING AND DISPLAYING IMAGES OF THE UNDERCARRIAGE OF VEHICLES - A portable undercarriage vehicle inspection system (UVIS) ( | 09-04-2008 |
Charles L. Hawes, Iii, Cordova, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20110190187 | ORGANIC RESIDUE REMOVER COMPOSITION - Organic residue remover composition useful to remove from very oily type soils to very watery contaminants from various surfaces, obtained by mixing: component (a): at least one water insoluble hydrophobic compound, component (b): at least one water soluble glycol ether, component (c): at least one water insoluble glycol ether, component (d): at least one aromatic alcohol, component (e): at least one surfactant, optionally component (f): at least one hydrotrope, and component (g): water, wherein each component or an ingredient thereof is different from the other components or ingredients thereof in the organic residue remover composition. | 08-04-2011 |
Charles L. Hites, Fraser, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20110061991 | MECHANICAL PALLET LIFT INCORPORATED INTO AN ASSEMBLY LINE PROCESS - A mechanical pallet lift, such as incorporated into a conveyor driven process, having a base. A lower frame is displaceably supported upon the base and includes a first plurality of upwardly extending and spaced apart walls. An upper frame includes a second plurality of downwardly extending and spaced apart walls which nest in offsetting fashion with the first plurality of walls in an initial position. A rotary driven crank includes a first linkage elevating the upper frame so that the second walls are located above the first walls, a second linkage successively displacing the lower frame to cause the first walls to align with the second walls concurrent with the first linkage reverse lowering the upper frame to seat upon the lower frame. A limit stroke bracket surrounds the base includes column supports which, upon shifting in the elevated position, are engaged by horizontal exterior supports mounted to said upper frame upon reverse actuating of said crank at an intermediate elevated position. | 03-17-2011 |
Charles L. Jaffe, Yavne IL
| Patent application number | Description | Published |
|---|---|---|
| 20100190795 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIPROTOZOAL AGENTS - The invention relates to betulin derivatives, and to the use thereof as agents against protozoa of the genus | 07-29-2010 |
Charles L. Johnson, Ventura, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20090018496 | DUAL CHAMBER MIXING SYRINGE AND METHOD FOR USE - A mixing syringe and method for using the mixing syringe are provided. The mixing syringe comprises a housing having a first compartment for containing a first component, an outer plunger having a second compartment for containing a second component, and an inner plunger. Prior to use, a seal separates the first and second components. To prepare the mixture, the seal is pierced and the two components are mixed. The mixing syringe and its method of use are particularly suited to applications in which at least one of the mixture components is a relatively highly viscous material. | 01-15-2009 |
Charles L. Magness, Seattle, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20090123472 | DETECTION OF MUTATIONS IN A GENE ASSOCIATED WITH RESISTANCE TO VIRAL INFECTION, OAS1 - A method for detecting a mutation related to the gene encoding OAS1. This and other disclosed mutations correlate with resistance of humans to viral infection including hepatitis C. Also provided is a therapeutic agent consisting of a protein or polypeptide encoded by the mutated gene, or a polynucleotide encoding the protein or polypeptide. Inhibitors of human OAS1, including antisense oligonucleotides, methods, and compositions specific for human OAS1, are also provided. | 05-14-2009 |
| 20090155234 | DETECTION OF MUTATIONS IN A GENE ASSOCIATED WITH RESISTANCE TO VIRAL INFECTION, MX1 - A method for detecting a mutation related to the gene encoding MxA. This and other disclosed mutations correlate with resistance of humans to viral infection including hepatitis C. Also provided is a therapeutic agent consisting of a protein or polypeptide encoded by the wild-type and mutated genes, or a polynucleotide encoding the protein or polypeptide. Inhibitors of human MxA, including antisense oligonucleotides, methods, and compositions specific for human MxA, are also provided. | 06-18-2009 |
| 20090186028 | Detection of mutations in a gene associated with resistance to viral infection - A method for detecting a mutation related to the gene encoding LDLR. This and other disclosed mutations correlate with resistance of humans to viral infection including hepatitis C. Also provided is a therapeutic agent consisting of a protein or polypeptide encoded by the wild-type and mutated genes, or a polynucleotide encoding the protein or polypeptide. Inhibitors of human LDLR, including antisense oligonucleotides, methods, and compositions specific for human LDLR, are also provided. | 07-23-2009 |
| 20090291074 | MUTATIONS IN OAS1 GENES - Modified amino acid sequences of OAS1 proteins in non-human primates, and genes related thereto, are provided. | 11-26-2009 |
| 20110071073 | Detection of mutations in a gene associated with resistance to viral infection, OAS1 - A method for detecting a mutation related to the gene encoding OAS1. This and other disclosed mutations correlate with resistance of humans to viral infection including hepatitis C. Also provided is a therapeutic agent consisting of a protein or polypeptide encoded by the mutated gene, or a polynucleotide encoding the protein or polypeptide. Inhibitors of human OAS1, including antisense oligonucleotides, methods, and compositions specific for human OAS1, are also provided. | 03-24-2011 |
| 20110237501 | Detection of Mutations in a Gene Associated with Resistance to Viral Infection, OAS1 - A method for detecting a mutation related to the gene encoding OAS1. This and other disclosed mutations correlate with resistance of humans to viral infection including hepatitis C. Also provided is a therapeutic agent consisting of a protein or polypeptide encoded by the mutated gene, or a polynucleotide encoding the protein or polypeptide. Inhibitors of human OAS1, including antisense oligonucleotides, methods, and compositions specific for human OAS1, are also provided. | 09-29-2011 |
Charles L. Mccormick, Iii, Hattiesburg, MS US
| Patent application number | Description | Published |
|---|---|---|
| 20090305045 | Preparation of Transition Metal Nanoparticles and Surfaces Modified with (CO)Polymers Synthesized by RAFT - A new, facile, general one-phase method of generating thiol-functionalized transition metal nanoparticles and surfaces modified by (co)polymers synthesized by the RAFT method is described. The method includes the steps of forming a (co)polymer in aqueous solution using the RAFT methodology, forming a colloidal transition metal precursor solution from an appropriate transition metal; adding the metal precursor solution or surface to the (co)polymer solution, adding a reducing agent into the solution to reduce the metal colloid in situ to produce the stabilized nanoparticles or surface, and isolating the stabilized nanoparticles or surface in a manner such that aggregation is minimized. The functionalized surfaces generated using these methods can further undergo planar surface modifications, such as functionalization with a variety of different chemical groups, expanding their utility and application. | 12-10-2009 |
Charles L. Nelson US
| Patent application number | Description | Published |
|---|---|---|
| 20110087227 | BONE FIXATION DEVICE, TOOLS AND METHODS - A bone fixation device is provided with an elongate body having a longitudinal axis and having a first state in which at least a portion of the body is flexible and a second state in which the body is generally rigid, an actuateable gripper disposed at one or more locations on the elongated body, a hub located on a proximal end of the elongated body, and an actuator operably connected to the gripper(s) to deploy the gripper(s) from a retracted configuration to an expanded configuration. Methods of repairing a fracture of a bone are also disclosed. One such method comprises inserting a bone fixation device into an intramedullary space of the bone to place at least a portion of an elongate body of the fixation device in a flexible state on one side of the fracture and at least a portion of a hub on another side of the fracture, and operating an actuator to deploy at least one gripper of the fixation device to engage an inner surface of the intramedullary space to anchor the fixation device to the bone. Various hub designs are disclosed that may be used in combination with other fixation device components. | 04-14-2011 |
Charles L. Pamplin, Iii, Chapel Hill, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20110033399 | THERAPEUTIC VITAMIN D SUN-PROTECTING FORMULATIONS AND METHODS FOR THEIR USE - The present invention concerns topical sun-protecting formulations including therapeutically effective amounts of Vitamin D, including formulations that provide Vitamin D in bioavailable amounts that correspond to decreased natural Vitamin D production resulting from the sun-blocking effects of the formulations and formulations for the prevention and treatment of disorders and disease states associated with vitamin D deficiency and vitamin D insufficiency. | 02-10-2011 |
Charles L. Pedersen, Virum DK
| Patent application number | Description | Published |
|---|---|---|
| 20080260198 | HEADSET - Communication unit comprising a housing ( | 10-23-2008 |
| 20080279403 | Headset and a Headphone - A headset ( | 11-13-2008 |
Charles L. Pizzano, Norwood, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090090166 | SHOCK SIMULATION GENERATOR - This is directed to systems, methods, computer programs and other means for shock testing a piece of equipment, i.e., the target. The target can be mounted to a shock generation machine, which is then slammed into a sturdy foundation. The impact can result in multi-axis loads, depending on how the machine is configured, while also simulating the modal frequency response of an object, such as a naval ship's deck. | 04-09-2009 |
Charles L. Spyres, Newark, DE US
| Patent application number | Description | Published |
|---|---|---|
| 20090273796 | PEELING IMAGED MEDIA FROM A SUBSTRATE - A method for imaging a media is provided which includes supporting a substrate and the media in a layered configuration. An imaging head is operated to image the media by directing radiation beams towards a surface of the imaged media while effecting relative movement between the imaging head and the support. A roller is brought into contact with the imaged media. The roller can be brought into contact with an un-imaged region of the surface of the imaged media, the un-imaged region corresponding to a region of the surface of the imaged media that is not impinged by the radiation beams. The un-imaged region could be an edge portion of the media. Relative movement is effected between an axis of rotation of the roller and the support to cause the roller to roll on the regions of the surface of the imaged media impinged by the radiation beams. | 11-05-2009 |
Charles L. Tazzia, Grosse Pointe Farms, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20080272005 | SOLID PIGMENTED RESIN-CROSSLINKER MIXTURE FOR USE IN AQUEOUS COATINGS - A pigmented granular pigmented coating feedstock is prepared by melting a resin, which can be a solid resin based on polymerizable ethylenically unsaturated monomer or epoxy based resin, and a solid or viscous curing agent, blending the molten mass, and cooling to form a solid. The solid blend of resin and curing agent is ground to produce a granular feedstock. The feedstock is readily storable or shippable to a location for coating preparation. Alternatively a solid coating can be ground after shipping. An aqueous coating is made by dispersing the feedstock in water and mixing to form a dispersion. A salting agent and at least one additive can be added to form an aqueous coating composition. An article can be coated with the dispersion, for example, by electrodeposition. | 11-06-2008 |
| 20080289539 | COATING COMPOSITIONS HAVING HYPERBRANCHED POLYMERS AND METHODS OF PRODUCING SAME - Coating compositions include a crosslinker and a hyperbranched polymer and methods of producing coating compositions include combining a crosslinker and a hyperbranched polymer. Branching portions of the hyperbranched polymer include a linkage via a carbonyl group and at least two linkages via methylene groups. Branching compounds used in a process to form a hyperbranched polymer include at least one hydroxyl group and at least two oxirane groups. Resulting hyperbranched polymers can include dendrimers. Coating compositions having hyperbranched polymers and crosslinkers can be applied to a substrate and cured to form a crosslinked film. | 11-27-2008 |
| 20090317645 | ELECTROCOAT COMPOSITION AND PROCESS - An electrodeposition coating composition comprises an unhydrolyzed or at least partially hydrolyzed polyvinyl formamide polymer for improved edge coverage of the coating when plated onto a conductive substrate. The plated coating can be cured. | 12-24-2009 |
| 20090326099 | PROCESS FOR CONTINUOUS PRODUCTION OF EPOXY RESINS - An epoxy resin with amine functionality is manufactured continuously through a first reaction zone in which an epoxide-functional resin is made by ring-opening addition, a second reaction zone in which the resin is reacted with amine to make an epoxide-functional product, and a third reaction zone in which the epoxide functional product is reacted with amine to make the epoxy resin with amine functionality. In other embodiments, some amine may be added in the first reaction zone to produce an epoxide functional product, with elimination of the second reaction zone, or all of the amine reactant may be added in the first reaction zone to produce an amine functional product, with elimination of both the second and third reaction zones. Optionally, solvent may be removed in an evaporation zone and recycled into the continuous process and further zones may be included to incorporate crosslinker, additives, and to emulsify the resin. | 12-31-2009 |
| 20090326173 | PROCESS FOR CONTINUOUS PRODUCTION OF EPOXY RESINS - An epoxy resin with amine functionality is manufactured continuously through a first reaction zone in which an epoxide-functional resin is made by ring-opening addition, a second reaction zone in which the resin is reacted with amine to make an epoxide-functional product, and a third reaction zone in which the epoxide functional product is reacted with amine to make the epoxy resin with amine functionality. In other embodiments, some amine may be added in the first reaction zone to produce an epoxide functional product, with elimination of the second reaction zone, or all of the amine reactant may be added in the first reaction zone to produce an amine functional product, with elimination of both the second and third reaction zones. Optionally, solvent may be removed in an evaporation zone and recycled into the continuous process and further zones may be included to incorporate crosslinker, additives, and to emulsify the resin. | 12-31-2009 |
| 20090326189 | PROCESS FOR CONTINUOUS PRODUCTION OF EPOXY RESINS - An epoxy resin with amine functionality is manufactured continuously through a first reaction zone in which an epoxide-functional resin is made by ring-opening addition, a second reaction zone in which the resin is reacted with amine to make an epoxide-functional product, and a third reaction zone in which the epoxide functional product is reacted with amine to make the epoxy resin with amine functionality. In other embodiments, some amine may be added in the first reaction zone to produce an epoxide functional product, with elimination of the second reaction zone, or all of the amine reactant may be added in the first reaction zone to produce an amine functional product, with elimination of both the second and third reaction zones. Optionally, solvent may be removed in an evaporation zone and recycled into the continuous process and further zones may be included to incorporate crosslinker, additives, and to emulsify the resin. | 12-31-2009 |
| 20100167070 | ACRYLIC ELECTROCOAT COMPOSITION AND PROCESS REPLACING PHOSPHATE PRETREATMENT - A coating composition, such as an electrodepositable electrocoat primer coating composition, comprises a phosphorylated acrylic polymer, The coating provides excellent corrosion protection even without a conventional phosphate pretreatment. | 07-01-2010 |
Charles L. Thomeczek, Jr., Batesville, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20120043865 | VERTICAL CABINET DOOR WITH FLUSH FRONT FACE - A headwall for a patient's room includes a panel having a vertically-extending front surface, an opening defined in the front surface of the headwall, and a door sized to be received in the opening. The door is vertically movable from a first position where an outer face of the door is flush with the front surface of the panel to a second position where the outer face extends parallel to the front surface and the door is positioned behind the front surface. | 02-23-2012 |
Charles L. Thomeczek, Jr., Fishera, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20100047736 | Handpiece for Detection of Dental Demineralization - A dental implement including a housing, a light source, and an air supply. | 02-25-2010 |
Charles L. Truwit, Wayzata, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20110022058 | Device for Immobilizing a Primary Instrument and Method Therefor - Devices and methods provide accurate targeting, placement, and/or stabilization of an electrode or other instrument(s) into the brain or other body organ, such as to treat severe tremor or other neurological disorders. Targeting is performed using any form of image-guidance, including real-time MRI, CT, or frameless surgical navigation systems. | 01-27-2011 |
| 20110022059 | Device for Immobilizing a Primary Instrument and Method Therefor - Devices and methods provide accurate targeting, placement, and/or stabilization of an electrode or other instrument(s) into the brain or other body organ, such as to treat severe tremor or other neurological disorders. Targeting is performed using any form of image-guidance, including real-time MRI, CT, or frameless surgical navigation systems. | 01-27-2011 |
Charles L. Van Sant, Grayslake, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20100184026 | Companion Diagnostic Assays For Endothelin Receptor Antagonists - Methods for identifying cancer patients eligible to receive endothelin receptor antagonist therapy and for monitoring patient response to endothelin receptor antagonist therapy comprise assessment of the expression levels of at least one of PAI-1, uPA, TGFbeta2, IL-6, IL-8 and OPG in a patient tissue sample. The methods of the invention allow more effective identification of patients to receive endothelin receptor antagonist therapy and of determination of patient response to the therapy. | 07-22-2010 |
Charles L. Zitnick, Iii, Seattle, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20110109755 | HARDWARE ASSISTED IMAGE DEBLURRING - The described implementations relate to deblurring images. One system includes an imaging device configured to capture an image, a linear motion detector and a rotational motion detector. This system also includes a controller configured to receive a signal from the imaging device relating to capture of the image and to responsively cause the linear motion detector and the rotational motion detector to detect motion-related information. Finally, this particular system includes a motion calculator configured to recover camera motion associated with the image based upon the detected motion-related information and to infer imaging device motion induced blur of the image and an image deblurring component configured to reduce imaging device induced blur from the image utilizing the inferred camera motion induced blur. | 05-12-2011 |